A mandatory single blastocyst transfer policy with educational campaign in a United States IVF program reduces multiple gestation rates without sacrificing pregnancy rates

Fertility and Sterility

Volumn 88, Issue 2, 2007, Pages 354-360

  Ryan, Ginny L ^a   Sparks, Amy E T ^a   Sipe, Christopher S ^a   Syrop, Craig H ^a   Dokras, Anuja ^a   Van Voorhis, Bradley J ^a  

^a UNIVERSITY OF IOWA   (United States)

Author keywords

blastocyst; blastocyst transfer; education; Infertility; IVF; multiple gestations; premature birth; twins

Indexed keywords

ADULT; ARTICLE; BLASTOCYST; EMBRYO TRANSFER; FEMALE; FERTILIZATION IN VITRO; HEALTH EDUCATION; HEALTH PROGRAM; HUMAN; INFERTILITY; MAJOR CLINICAL STUDY; MALE; MULTIPLE PREGNANCY; OUTCOMES RESEARCH; PATIENT EDUCATION; PREGNANCY RATE; PRIORITY JOURNAL; PROSPECTIVE STUDY; RETROSPECTIVE STUDY; TWIN PREGNANCY; UNITED STATES;

ADULT; CELL COUNT; EMBRYO TRANSFER; FEMALE; FERTILIZATION IN VITRO; HEALTH KNOWLEDGE, ATTITUDES, PRACTICE; HUMANS; MALE; PATIENT EDUCATION; PATIENT SATISFACTION; PREGNANCY; PREGNANCY RATE; PREGNANCY, MULTIPLE; TWINS; UNITED STATES;

EID: 34547692722     PISSN: 00150282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fertnstert.2007.03.001     Document Type: Article

References (30)

1. ESHRE Campus Course Report. Prevention of twin pregnancies after IVF/ICSI by single embryo transfer. Hum Reprod 16 (2001) 790-800
2. Practice Committee of the Society for Assisted Reproductive Technology and the American Society for Reproductive Medicine. Guidelines on the number of embryos transferred. Fertil Steril 82 (2004) 773-774
3. ESHRE Task Force on Ethics and Law. 6. Ethical issues related to multiple pregnancies in medically assisted procreation. Hum Reprod 18 (2003) 1976-1979
4. Kissin D.M., Schieve L.A., and Reynolds M.A. Multiple-birth risk associated with IVF and extended embryo culture: USA, 2001. Hum Reprod 20 (2006) 2215-2223
5. Jain T., Missmer S.A., and Hornstein M.D. Trends in embryo-transfer practice and in outcomes of the use of assisted reproductive technology in the United States. N Engl J Med 350 (2004) 1639-1645
6. Pinborg A. IVF/ICSI twin pregnancies: risks and prevention. Hum Reprod Update 11 (2005) 575-593
7. ASRM Practice Committee Report. Multiple pregnancy associated with infertility therapy (2000), American Society for Reproductive Medicine, Birmingham, AL
8. Schieve L.A., Peterson H.B., Meikle S.F., Jeng G., Danel I., Burnett N.M., et al. Live-birth rates and multiple-birth risk using in vitro fertilization. JAMA 282 (1999) 1832-1838
9. Ryan G.L., Zhang S.H., Dokras A., Syrop C.H., and Van Voorhis B.J. The desire of infertile patients for multiple births. Fertil Steril 81 (2004) 500-504
10. Child T.J., Henderson A.M., and Tan S.L. The desire for multiple pregnancy in male and female infertility patients. Hum Reprod 19 (2004) 558-561
11. Pinborg A., Loft A., Schmidt L., and Andersen A.N. Attitudes of IVF/ICSI-twin mothers towards twins and single embryo transfer. Hum Reprod 18 (2003) 621-627
12. Murray S., Shetty A., Rattray A., Taylor V., and Bhattacharya S. A randomized comparison of alternative methods of information provision on the acceptability of elective single embryo transfer. Hum Reprod 19 (2004) 911-916
13. Pinborg A., Loft A., Schmidt L., and Andersen A.N. Morbidity in a Danish national cohort of 472 IVF/ICSI twins, 1132 nonIVF/ICSI twins and 634 IVF/ICSI singletons: health-related and social implications for the children and their families. Hum Reprod 18 (2003) 1234-1243
14. Glazebrook C., Sheard C., Cox S., Oates M., and Ndukwe G. Parenting stress in first-time mothers of twins and triplets conceived after in vitro fertilization. Fertil Steril 81 (2004) 505-511
15. Scher A.I., Petterson B., Blair E., Ellenberg J.H., Grether J.K., Haan E., et al. The risk of mortality or cerebral palsy in twins: a collaborative population-based study. Pediatr Res 52 (2002) 671-681
16. Pharoah P.O. Neurological outcome in twins. Semin Neonatol 7 (2002) 223-230
17. ESHRE Capri Workshop Group. Multiple gestation pregnancy. Hum Reprod 5 (2000) 1856-1864
18. Rutter M., Thorpe K., Greenwood R., Northstone K., and Golding J. Twins as a natural experiment to study the causes of mild language delay: I: design; twin-singleton differences in language, and obstetric risks. J Child Psychol Psychiatry 44 (2003) 326-341
19. Olivennes F., Golombok S., Ramogida C., Rust J., and Follow-Up Team. Behavioral and cognitive development as well as family functioning of twins conceived by assisted reproduction: findings from a large population study. Fertil Steril 84 (2005) 725-733
20. Ellison M.A., Hotamisligil S., Lee H., Rich-Edwards J.W., Pang S.C., and Hall J.E. Psychosocial risks associated with multiple births resulting from assisted reproduction. Fertil Steril 83 (2005) 1422-1428
21. Dokras A., Baredziak L., Blaine J., Syrop C., Van Voorhis B.J., and Sparks A. Obstetric outcomes after in vitro fertilization in obese and morbidly obese women. Obstet Gynecol 108 (2006) 61-69
22. Gardner D.K., and Schoolcraft W.B. In-vitro culture of human blastocysts. In: Jansen R., and Mortimer D. (Eds). Towards reproductive certainty: fertility and genetics beyond 1999 (1999), Parthenon Press, Carnforth 378-388
23. Criniti A., Thyer A., Chow G., Lin P., Klein N., and Soules M. Elective single blastocyst transfer reduces twin rates without compromising pregnancy rates. Fertil Steril 84 (2005) 1613-1619
24. Gardner D.K., Surrey E., Minjarez D., Leitz A., Stevens J., and Schoolcraft W.B. Single blastocyst transfer: a prospective randomized trial. Fertil Steril 81 (2004) 551-555
25. Pennings G. Multiple pregnancies: a test case for the moral quality of medically assisted reproduction. Hum Reprod 15 (2000) 2466-2469
26. Kassirer J.P. Incorporating patients' preferences into medical decisions. N Engl J Med 330 (1994) 1895-1896
27. Montgomery A.A., and Fahey T. How do patients' treatment preferences compare with those of clinicians?. Qual Health Care 10 (2001) i39-i43
28. Secker B. The appearance of Kant's deontology in contemporary Kantianism: concepts of patient autonomy in bioethics. J Med Philos 24 (1999) 43-66
29. Schieve L.A. The promise of single-embryo transfer. N Engl J Med 354 (2006) 1190-1193
30. Jain T. Socioeconomic and racial disparities among infertility patients seeking care. Fertil Steril 85 (2006) 876-881