Plasma morphine and metabolite concentrations are associated with clinical effects of morphine in cancer patients

Journal of Pain and Symptom Management

Volumn 45, Issue 4, 2013, Pages 670-680

  Gretton, Sophy K ^a,b   Ross, Joy R ^a,b   Rutter, Dag ^c   Sato, Hiroe ^b   Droney, Joanne M ^a,b   Welsh, Kenneth I ^b   Joel, Simon ^d   Riley, Julia ^a  

^a ROYAL MARSDEN HOSPITAL   (United Kingdom)

^b IMPERIAL COLLEGE LONDON   (United Kingdom)

^c MAIDSTONE AND TUNBRIDGE WELLS NHS TRUST   (United Kingdom)

^d ST BARTHOLOMEW S HOSPITAL   (United Kingdom)

Author keywords

Cancer; metabolite; morphine; opioid; pain; responder; switcher

Indexed keywords

MORPHINE; MORPHINE 3 GLUCURONIDE; MORPHINE 6 GLUCURONIDE;

ADULT; ALCOHOL CONSUMPTION; ARTICLE; BLOOD SAMPLING; BRIEF PAIN INVENTORY; CANCER PAIN; CANCER PALLIATIVE THERAPY; CANCER PATIENT; CONFUSION; CONSTIPATION; CREATININE CLEARANCE; DIARRHEA; DROWSINESS; DRUG BLOOD LEVEL; FEMALE; HALLUCINATION; HUMAN; HUMAN TISSUE; LIMIT OF QUANTITATION; MAJOR CLINICAL STUDY; MALE; MYOCLONUS; NAUSEA; NIGHTMARE; PAIN ASSESSMENT; PHENOTYPE; PROSPECTIVE STUDY; PRURITUS; TREATMENT RESPONSE; VOMITING;

ANALGESICS, OPIOID; BIOLOGICAL MARKERS; CAUSALITY; COMORBIDITY; FEMALE; GREAT BRITAIN; HUMANS; MALE; MIDDLE AGED; MORPHINE; NEOPLASMS; OPIOID-RELATED DISORDERS; PAIN; PAIN MEASUREMENT; PREVALENCE; RISK FACTORS; STATISTICS AS TOPIC; TREATMENT OUTCOME;

EID: 84875730611     PISSN: 08853924     EISSN: 18736513     Source Type: Journal    
DOI: 10.1016/j.jpainsymman.2012.03.015     Document Type: Article

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