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Volumn 41, Issue 2, 2013, Pages 374-386

The toxicity and pathology of selected dietary herbal medicines

Author keywords

Aloe vera whole leaf nondecolorized extract; ginkgo; ginseng; goldenseal; kava kava; milk thistle; turmeric oleoresin

Indexed keywords

ALOE BARBADENSIS EXTRACT; CURCUMA LONGA EXTRACT; GINKGO BILOBA EXTRACT; GINSENG EXTRACT; HYDRASTIS CANADENSIS EXTRACT; KAVA EXTRACT; PLANT EXTRACT; SILYBUM MARIANUM EXTRACT; UNCLASSIFIED DRUG;

EID: 84875728723     PISSN: 01926233     EISSN: 15331601     Source Type: Journal    
DOI: 10.1177/0192623312466451     Document Type: Article
Times cited : (51)

References (60)
  • 2
    • 3242884003 scopus 로고    scopus 로고
    • Prediction of rodent carcinogenesis: An evaluation of prechronic liver lesions as forecasters of liver tumors in NTP carcinogenicity studies
    • Allen D. G., Pearse G., Haseman J. K., Maronpot R. R.. Prediction of rodent carcinogenesis: An evaluation of prechronic liver lesions as forecasters of liver tumors in NTP carcinogenicity studies. Toxicol Pathol. 2004 ; 32: 393-401
    • (2004) Toxicol Pathol , vol.32 , pp. 393-401
    • Allen, D.G.1    Pearse, G.2    Haseman, J.K.3    Maronpot, R.R.4
  • 4
    • 0023677290 scopus 로고
    • Effects of treatment-induced mortality and tumor-induced mortality on tests for carcinogenicity in small samples
    • Bailer A. J., Portier C. J.. Effects of treatment-induced mortality and tumor-induced mortality on tests for carcinogenicity in small samples. Biometrics. 1988 ; 44: 417-31
    • (1988) Biometrics , vol.44 , pp. 417-431
    • Bailer, A.J.1    Portier, C.J.2
  • 7
    • 0031039049 scopus 로고    scopus 로고
    • Assessment of the genotoxic risk from laxative senna products
    • Brusick D., Mengs U.. Assessment of the genotoxic risk from laxative senna products. Envirn Mol Mutagen. 1997 ; 29: 1-9
    • (1997) Envirn Mol Mutagen , vol.29 , pp. 1-9
    • Brusick, D.1    Mengs, U.2
  • 8
    • 70350437252 scopus 로고    scopus 로고
    • American roulette - Contaminated dietary supplements
    • Cohen P. A.. American roulette - Contaminated dietary supplements. N Engl J Med. 2009 ; 361: 1523-25
    • (2009) N Engl J Med , vol.361 , pp. 1523-1525
    • Cohen, P.A.1
  • 11
    • 0028947780 scopus 로고
    • Further evidence for promoter-dependent development of hepatoblastoma in the mouse
    • Diwan B. A., Henneman J. R., Rice J. M.. Further evidence for promoter-dependent development of hepatoblastoma in the mouse. Cancer Lett. 1995 ; 89: 29-35
    • (1995) Cancer Lett , vol.89 , pp. 29-35
    • Diwan, B.A.1    Henneman, J.R.2    Rice, J.M.3
  • 14
    • 78651401023 scopus 로고    scopus 로고
    • Autoxidative and cyclooxygenase-2 catalyzed transformation of the dietary chemopreventive agent curcumin
    • Griesser M., Pistis V., Suzuki T., Tejera N., Pratt D. A., Schneider C.. Autoxidative and cyclooxygenase-2 catalyzed transformation of the dietary chemopreventive agent curcumin. J Biol Chem. 2011 ; 286: 1114-24
    • (2011) J Biol Chem , vol.286 , pp. 1114-1124
    • Griesser, M.1    Pistis, V.2    Suzuki, T.3    Tejera, N.4    Pratt, D.A.5    Schneider, C.6
  • 15
    • 84863115185 scopus 로고    scopus 로고
    • Discovery of curcumin, a component of golden spice, and its miraculous biological activities
    • Gupta S. C., Patchva S., Koh W., Aggarwal B. B.. Discovery of curcumin, a component of golden spice, and its miraculous biological activities. Clin Exp Pharmacol Physiol. 2012 ; 39: 283-99
    • (2012) Clin Exp Pharmacol Physiol , vol.39 , pp. 283-299
    • Gupta, S.C.1    Patchva, S.2    Koh, W.3    Aggarwal, B.B.4
  • 24
    • 84861176603 scopus 로고    scopus 로고
    • Ginsenoside Rg3 attenuates tumor angiogenesis via inhibiting bioactivities of endothelial progenitor cells
    • Kim J. W., Jung S. Y., Kwon Y. H., Lee J. H., Lee Y. M., Lee B. Y., Kwon S. M.. Ginsenoside Rg3 attenuates tumor angiogenesis via inhibiting bioactivities of endothelial progenitor cells. Cancer Biol Ther. 2012 ; 13 :
    • (2012) Cancer Biol Ther , vol.13
    • Kim, J.W.1    Jung, S.Y.2    Kwon, Y.H.3    Lee, J.H.4    Lee, Y.M.5    Lee, B.Y.6    Kwon, S.M.7
  • 28
    • 0002073011 scopus 로고
    • Protoberberine alkaloids and related compounds as dual inhibitors of mammalian topisomerase i and II
    • Makhey D., Gatto B., Yu C., Liu A., Liu L. F., LaVoie E. J.. Protoberberine alkaloids and related compounds as dual inhibitors of mammalian topisomerase I and II. Med Chem Res. 1994 ; 5: 1-12
    • (1994) Med Chem Res , vol.5 , pp. 1-12
    • Makhey, D.1    Gatto, B.2    Yu, C.3    Liu, A.4    Liu, L.F.5    Lavoie, E.J.6
  • 30
    • 54349084283 scopus 로고    scopus 로고
    • Hepatic metabolism and biliary excretion of silymarin flavonolignans in isolated perfused rat livers: Role of multidrug resistance-associated protein 2 (Abcc2)
    • Miranda S. R., Lee J. K., Brouwer K. L., Wen Z., Smith P. C., Hawke R. L.. Hepatic metabolism and biliary excretion of silymarin flavonolignans in isolated perfused rat livers: Role of multidrug resistance-associated protein 2 (Abcc2). Drug Metab Dispos. 2008 ; 36: 2219-26
    • (2008) Drug Metab Dispos , vol.36 , pp. 2219-2226
    • Miranda, S.R.1    Lee, J.K.2    Brouwer, K.L.3    Wen, Z.4    Smith, P.C.5    Hawke, R.L.6
  • 31
    • 79952441656 scopus 로고    scopus 로고
    • Is senna laxative use associated to cathartic colon, genotoxicity, or carcinogenicity?
    • Morales M. A., Hernandez D., Bustamante S., Bachiller I., Rojas A.. Is senna laxative use associated to cathartic colon, genotoxicity, or carcinogenicity?. J Toxicol. 2009 ; 2009: 287247
    • (2009) J Toxicol , vol.2009 , pp. 287247
    • Morales, M.A.1    Hernandez, D.2    Bustamante, S.3    Bachiller, I.4    Rojas, A.5
  • 32
    • 0022355798 scopus 로고
    • Induction of intestinal tumours in rats by chrysazin
    • Mori H., Sugie K., Niwa M., Takahashi M., Kawai K.. Induction of intestinal tumours in rats by chrysazin. Br J Cancer. 1985 ; 52: 781-83
    • (1985) Br J Cancer , vol.52 , pp. 781-783
    • Mori, H.1    Sugie, K.2    Niwa, M.3    Takahashi, M.4    Kawai, K.5
  • 34
    • 0025361213 scopus 로고
    • Carcinogenicity of naturally occurring 1-hydroxyanthraquinone in rats: Induction of large bowel, liver and stomach neoplasms
    • Mori H., Yoshimi N., Iwata H., Mori Y., Hara A., Tanaka T., Kawai K.. Carcinogenicity of naturally occurring 1-hydroxyanthraquinone in rats: Induction of large bowel, liver and stomach neoplasms. Carcinogenesis. 1990 ; 11: 799-802
    • (1990) Carcinogenesis , vol.11 , pp. 799-802
    • Mori, H.1    Yoshimi, N.2    Iwata, H.3    Mori, Y.4    Hara, A.5    Tanaka, T.6    Kawai, K.7
  • 35
    • 84865039191 scopus 로고    scopus 로고
    • Ginsenosides as anticancer agents: In vitro and in vivo activities, structure-activity relationships, and molecular mechanisms of action
    • Nag S. A., Qin J. J., Wang W., Wang M. H., Wang H., Zhang R.. Ginsenosides as anticancer agents: In vitro and in vivo activities, structure-activity relationships, and molecular mechanisms of action. Front Pharmacol. 2012 ; 3: 25
    • (2012) Front Pharmacol , vol.3 , pp. 25
    • Nag, S.A.1    Qin, J.J.2    Wang, W.3    Wang, M.H.4    Wang, H.5    Zhang, R.6
  • 36
    • 77954960842 scopus 로고    scopus 로고
    • Health need and the use of alternative medicine among adults who do not use conventional medicine
    • Nahin R. L., Dahlhamer J. M., Stussman B. J.. Health need and the use of alternative medicine among adults who do not use conventional medicine. BMC Health Serv Res. 2010 ; 10: 220
    • (2010) BMC Health Serv Res , vol.10 , pp. 220
    • Nahin, R.L.1    Dahlhamer, J.M.2    Stussman, B.J.3
  • 37
    • 37249013214 scopus 로고    scopus 로고
    • NIH (National Institutes of Health) Accessed December 2011
    • NIH (National Institutes of Health) (2011). ClinicalTrials.gov. http://www.clinicaltrials.gov/. Accessed December 2011.
    • (2011) ClinicalTrials.gov
  • 38
    • 84875721450 scopus 로고    scopus 로고
    • NIH Office of Dietary Supplements Accessed December 2011
    • NIH Office of Dietary Supplements (2011). Kava. http://ods.od.nih.gov/ Health-Information/kava.aspx. Accessed December 2011.
    • (2011) Kava
  • 39
    • 20844434618 scopus 로고
    • NTP toxicology and carcinogenesis studies of turmeric oleoresin (CAS No. 8024-37-1) (major component 79%-85% curcumin, CAS No. 458-37-7) in F344/N rats and B6C3F1 mice (feed studies)
    • NTP toxicology and carcinogenesis studies of turmeric oleoresin (CAS No. 8024-37-1) (major component 79%-85% curcumin, CAS No. 458-37-7) in F344/N rats and B6C3F1 mice (feed studies). Natl Toxicol Progr Tech Rep Ser. 1993 ; 427: 1-275
    • (1993) Natl Toxicol Progr Tech Rep ser , vol.427 , pp. 1-275
  • 40
    • 34548042952 scopus 로고    scopus 로고
    • Toxicology and carcinogenesis studies of Emodin (Cas.No. 518-82-1) feed studies in F344/N rats and B6C3F1 mice
    • Toxicology and carcinogenesis studies of Emodin (Cas.No. 518-82-1) feed studies in F344/N rats and B6C3F1 mice. Technical Report. 2001 ; 493 :
    • (2001) Technical Report , vol.493
  • 41
    • 84996503842 scopus 로고    scopus 로고
    • Toxicology and carcinogenesis studies of Goldenseal root powder (Hydrastis canadensis) in F344/N rats and B6C3F1 mice (feed studies)
    • Toxicology and carcinogenesis studies of Goldenseal root powder (Hydrastis canadensis) in F344/N rats and B6C3F1 mice (feed studies). Natl Toxicol Progr Tech Rep Ser. 2010 ; 562: 1-188
    • (2010) Natl Toxicol Progr Tech Rep ser , vol.562 , pp. 1-188
  • 42
    • 84887263029 scopus 로고    scopus 로고
    • NTP toxicology and carcinogenesis studies of whole leaf extract of aloe barbadensis miller (Aloe vera) in F344/N rats and B6C3F1 mice (Feed Studies)
    • NTP toxicology and carcinogenesis studies of whole leaf extract of aloe barbadensis miller (Aloe vera) in F344/N rats and B6C3F1 mice (Feed Studies). Natl Toxicol Progr Tech Rep Ser. 2011a ; 577: 1-293
    • (2011) Natl Toxicol Progr Tech Rep ser , vol.577 , pp. 1-293
  • 43
    • 84887262731 scopus 로고    scopus 로고
    • NTP toxicology and carcinogenesis studies of ginseng(CAS No. 50647-08-0) in F344/N rats and B6C3F1 mice (feed studies)
    • NTP toxicology and carcinogenesis studies of ginseng(CAS No. 50647-08-0) in F344/N rats and B6C3F1 mice (feed studies). Natl Toxicol Progr Tech Rep Ser. 2011b ; 567: 1-150
    • (2011) Natl Toxicol Progr Tech Rep ser , vol.567 , pp. 1-150
  • 44
    • 84863617682 scopus 로고    scopus 로고
    • NTP toxicology and carcinogenesis studies of if kava kava extract (CAS No. 9000-38-8) in F344/N rats and B6C3F1 mice (gavage studies)
    • NTP toxicology and carcinogenesis studies of if kava kava extract (CAS No. 9000-38-8) in F344/N rats and B6C3F1 mice (gavage studies). Natl Toxicol Progr Tech Rep Ser. 2011c ; 571: 1-186
    • (2011) Natl Toxicol Progr Tech Rep ser , vol.571 , pp. 1-186
  • 45
    • 84887262656 scopus 로고    scopus 로고
    • Toxicology and carcinogenesis studies of milk thstle extract (CAS No. 84604-20-6) in F344/N rats and B6c3f1 mice (Gavage Studies)
    • Toxicology and carcinogenesis studies of milk thstle extract (CAS No. 84604-20-6) in F344/N rats and B6c3f1 mice (Gavage Studies). Natl Toxicol Progr Tech Rep Ser. 2011d ; 564: 1-178
    • (2011) Natl Toxicol Progr Tech Rep ser , vol.564 , pp. 1-178
  • 46
    • 84887262094 scopus 로고    scopus 로고
    • NTP toxicology and carcinogenesis studies of Ginkgo biloba extract CAS No. 90045-35-6) in F344/N rats and B6C3F1 mice (Feed Studies
    • NTP toxicology and carcinogenesis studies of Ginkgo biloba extract CAS No. 90045-35-6) in F344/N rats and B6C3F1 mice (Feed Studies. Natl Toxicol Progr Tech Rep Ser. 2012 ; 578: 1-224
    • (2012) Natl Toxicol Progr Tech Rep ser , vol.578 , pp. 1-224
  • 48
    • 84875710139 scopus 로고    scopus 로고
    • Hall C. A., ed. London: Chapman and Hall;
    • Piegorsch W. W., Bailer A. J. Hall C. A., ed. London: Chapman and Hall ; 1997 :
    • (1997)
    • Piegorsch, W.W.1    Bailer, A.J.2
  • 49
    • 77957177350 scopus 로고
    • Testing for increased carcinogenicity using a survival-adjusted quantal response test
    • Portier C. J., Bailer A. J.. Testing for increased carcinogenicity using a survival-adjusted quantal response test. Fundam Appl Toxicol. 1989 ; 12: 731-37
    • (1989) Fundam Appl Toxicol , vol.12 , pp. 731-737
    • Portier, C.J.1    Bailer, A.J.2
  • 50
    • 0027502038 scopus 로고
    • Drug metabolism in the nasal cavity: Relevance to toxicology
    • Reed C. J.. Drug metabolism in the nasal cavity: Relevance to toxicology. Drug Metab Rev. 1993 ; 25: 173-205
    • (1993) Drug Metab Rev , vol.25 , pp. 173-205
    • Reed, C.J.1
  • 52
    • 50049099550 scopus 로고    scopus 로고
    • The pharmacokinetics of silymarin is altered in patients with hepatitis C virus and nonalcoholic fatty liver disease and correlates with plasma caspase-3/7 activity
    • Schrieber S. J., Wen Z., Vourvahis M., Smith P. C., Fried M. W., Kashuba A. D., Hawke R. L.. The pharmacokinetics of silymarin is altered in patients with hepatitis C virus and nonalcoholic fatty liver disease and correlates with plasma caspase-3/7 activity. Drug Metab Dispos. 2008 ; 36: 1909-16
    • (2008) Drug Metab Dispos , vol.36 , pp. 1909-1916
    • Schrieber, S.J.1    Wen, Z.2    Vourvahis, M.3    Smith, P.C.4    Fried, M.W.5    Kashuba, A.D.6    Hawke, R.L.7
  • 54
    • 84858072552 scopus 로고    scopus 로고
    • The pharmacology of curcumin: Is it the degradation products?
    • Shen L., Ji H. F.. The pharmacology of curcumin: Is it the degradation products?. Trends Mol Med. 2012 ; 18: 138-44
    • (2012) Trends Mol Med , vol.18 , pp. 138-144
    • Shen, L.1    Ji, H.F.2
  • 55
    • 84862248921 scopus 로고    scopus 로고
    • Cancer cell signaling pathways targeted by spice-derived nutraceuticals
    • Sung B., Prasad S., Yadav V. R., Aggarwal B. B.. Cancer cell signaling pathways targeted by spice-derived nutraceuticals. Nutr Cancer. 2012 ; 64: 173-97
    • (2012) Nutr Cancer , vol.64 , pp. 173-197
    • Sung, B.1    Prasad, S.2    Yadav, V.R.3    Aggarwal, B.B.4
  • 58
    • 84875732375 scopus 로고    scopus 로고
    • U.S. Food and Drug Administration Accessed June 2012
    • U.S. Food and Drug Administration (2011). Regulatory Framework of DSHEA of 1994. http://www.fda.gov/NewsEvents/Testimony/ucm115163.htm. Accessed June 2012.
    • (2011) Regulatory Framework of DSHEA of 1994
  • 59
    • 0004086066 scopus 로고    scopus 로고
    • U.S. Food and Drug Administration Accessed June 2012
    • U.S. Food and Drug Administration (2012). Dietary Supplement Health and Education Act of 1994. http://www.fda.gov/RegulatoryInformation/Legislation/ FederalFoodDrugandCosmeticActFDCAct/SignificantAmendmentstotheFDCAct/ucm148003. htm. Accessed June 2012.
    • (2012) Dietary Supplement Health and Education Act of 1994
  • 60
    • 36849036878 scopus 로고    scopus 로고
    • Evaluation of commercial kava extracts and kavalactone standards for mutagenicity and toxicity using the mammalian cell gene mutation assay in L5178Y mouse lymphoma cells
    • Whittaker P., Clarke J. J., San R. H., Betz J. M., Seifried H. E., de Jager L. S., Dunkel V. C.. Evaluation of commercial kava extracts and kavalactone standards for mutagenicity and toxicity using the mammalian cell gene mutation assay in L5178Y mouse lymphoma cells. Food Chem Toxicol. 2008 ; 46: 168-74
    • (2008) Food Chem Toxicol , vol.46 , pp. 168-174
    • Whittaker, P.1    Clarke, J.J.2    San, R.H.3    Betz, J.M.4    Seifried, H.E.5    De Jager, L.S.6    Dunkel, V.C.7


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