Aloe vera non-decolorized whole leaf extract-induced large intestinal tumors in F344 rats share similar molecular pathways with human sporadic colorectal tumors

Toxicologic Pathology

Volumn 39, Issue 7, 2011, Pages 1065-1074

  Pandiri, Arun R ^a,b   Sills, Robert C ^a   Hoenerhoff, Mark J ^a   Peddada, Shyamal D ^a   Ton, Thai Vu T ^a   Hong, Hue Hua L ^a   Flake, Gordon P ^a   Malarkey, David E ^a   Olson, Greg R ^c   Pogribny, Igor P ^d   Walker, Nigel J ^a   Boudreau, Mary D ^d  

^a NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^b EXPERIMENTAL PATHOLOGY LABORATORIES INC   (United States)

^c Toxicologic Pathology Associates   (United States)

^d NATIONAL CENTER FOR TOXICOLOGICAL RESEARCH   (United States)

Author keywords

Aloe vera; colon; colorectal tumors; F344 rat; human

Indexed keywords

ALOE BARBADENSIS EXTRACT; ALOE VERA EXTRACT; DRINKING WATER; MITOGEN ACTIVATED PROTEIN KINASE; TRANSFORMING GROWTH FACTOR BETA; WNT PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COLORECTAL TUMOR; CONTROLLED STUDY; CTNNB1 GENE; FISCHER 344 RAT; HUMAN; INTESTINE CARCINOMA; LARGE INTESTINE TUMOR; NONHUMAN; ONCOGENE K RAS; POINT MUTATION; PRIORITY JOURNAL; RAT; TUMOR SUPPRESSOR GENE;

ADENOMA; ALOE; ANIMALS; COLORECTAL NEOPLASMS; DISEASE MODELS, ANIMAL; HISTOCYTOCHEMISTRY; HUMANS; INTESTINAL NEOPLASMS; INTESTINE, LARGE; PLANT EXTRACTS; PLANT LEAVES; PRINCIPAL COMPONENT ANALYSIS; RATS; RATS, INBRED F344; SIGNAL TRANSDUCTION; TUMOR MARKERS, BIOLOGICAL;

EID: 82355175360     PISSN: 01926233     EISSN: 15331601     Source Type: Journal    
DOI: 10.1177/0192623311422081     Document Type: Article

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