Inhibition of CaMKII phosphorylation of RyR2 prevents inducible ventricular arrhythmias in mice with Duchenne muscular dystrophy

Heart Rhythm

Volumn 10, Issue 4, 2013, Pages 592-599

  Ather, Sameer ^a   Wang, Wei ^a   Wang, Qiongling ^a   Li, Na ^a   Anderson, Mark E ^b   Wehrens, Xander H T ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF IOWA   (United States)

Author keywords

Ca2+ calmodulin dependent protein kinase II; Cardiac arrhythmias; Duchenne muscular dystrophy; Mouse model; Ryanodine receptor; Ventricular tachycardia

Indexed keywords

CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; CALCIUM ION; CYCLIC AMP DEPENDENT PROTEIN KINASE; RYANODINE RECEPTOR 2;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARRHYTHMOGENESIS; ARTICLE; CALCIUM TRANSPORT; CONTROLLED STUDY; DUCHENNE MUSCULAR DYSTROPHY; ELECTRODE; ELECTROSTIMULATION; HEART MUSCLE CELL; HEART VENTRICLE ARRHYTHMIA; INHIBITION KINETICS; MALE; MOLECULAR IMAGING; MOUSE; MUTATIONAL ANALYSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; STEADY STATE; WESTERN BLOTTING; WILD TYPE;

ANIMALS; BLOTTING, WESTERN; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 2; CELLS, CULTURED; DISEASE MODELS, ANIMAL; ELECTRIC STIMULATION; GENE EXPRESSION REGULATION; MICE; MICE, INBRED MDX; MUSCLE CELLS; MUSCULAR DYSTROPHY, DUCHENNE; MUTATION; PHOSPHORYLATION; RANDOM ALLOCATION; RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL; SENSITIVITY AND SPECIFICITY; TACHYCARDIA, VENTRICULAR;

EID: 84875707515     PISSN: 15475271     EISSN: 15563871     Source Type: Journal    
DOI: 10.1016/j.hrthm.2012.12.016     Document Type: Article

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