Roles of Wnt/β-catenin signaling in retinal neuron-like differentiation of bone marrow mesenchymal stem cells from nonobese diabetic mice

Journal of Molecular Neuroscience

Volumn 49, Issue 2, 2013, Pages 250-261

  Xu, Yue ^a   Gu, Zhifeng ^a   Shen, Biyu ^a   Xu, Guofeng ^b   Zhou, Tianqiu ^a   Jiang, Jinxia ^a   Xing, Jing ^a   Liu, Suzhe ^a   Li, Man ^a   Tan, Wei ^a   Feng, Guijuan ^a   Sang, Aimin ^a   Li, Liren ^a  

^a NANTONG UNIVERSITY   (China)

^b NANJING MEDICAL UNIVERSITY   (China)

Author keywords

BM MSCs; Diabetic retinopathy; Differentiation; NOD mice; Wnt catenin signaling

Indexed keywords

BETA CATENIN; BRAIN DERIVED NEUROTROPHIC FACTOR; FIBROBLAST GROWTH FACTOR 2; GLIAL FIBRILLARY ACIDIC PROTEIN; GLUTAMATE AMMONIA LIGASE; NERVE GROWTH FACTOR; NEURON SPECIFIC NUCLEAR PROTEIN; RHODOPSIN; THY 1 ANTIGEN; TYROSINE 3 MONOOXYGENASE; WNT PROTEIN; WNT1 PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; DIABETIC RETINOPATHY; FEMALE; HEMATOPOIETIC STEM CELL; IMMUNOFLUORESCENCE; MESENCHYMAL STEM CELL; MOUSE; NONHUMAN; NONOBESE DIABETIC MOUSE; PROTEIN EXPRESSION; RETINA NERVE CELL; SIGNAL TRANSDUCTION; UPREGULATION; WESTERN BLOTTING;

ANIMALS; BETA CATENIN; BIOLOGICAL MARKERS; BRAIN-DERIVED NEUROTROPHIC FACTOR; CELL DIFFERENTIATION; FEMALE; FIBROBLAST GROWTH FACTORS; GENE EXPRESSION REGULATION; MESENCHYMAL STROMAL CELLS; MICE; MICE, INBRED NOD; NERVE GROWTH FACTOR; RETINAL NEURONS; WNT PROTEINS; WNT SIGNALING PATHWAY;

MUS;

EID: 84875702818     PISSN: 08958696     EISSN: 15591166     Source Type: Journal    
DOI: 10.1007/s12031-012-9917-z     Document Type: Article

References (40)

1. Barber AJ (2003) A new view of diabetic retinopathy: a neurodegenerative disease of the eye. Prog Neuropsychopharmacol Biol Psychiatry 27:283-290 (Pubitemid 36351495)
2. Caldwell RB, Bartoli M, Behzadian MA, El-Remessy AE, Al-Shabrawey M, Platt DH, Liou GI, Caldwell RW (2005) Vascular endothelial growth factor and diabetic retinopathy: role of oxidative stress. Curr Drug Targets 6:511-524 (Pubitemid 40916276)
3. Cao Y, Sun Z, Liao L, Meng Y, Han Q, Zhao RC (2005) Human adipose tissue-derived stem cells differentiate into endothelial cells in vitro and improve postnatal neovascularization in vivo. Biochem Biophys Res Commun 332:370-379 (Pubitemid 40724988)
4. Chamberlain G, Fox J, Ashton B, Middleton J (2007) Concise review: mesenchymal stem cells: their phenotype, differentiation capacity, immunological features, and potential for homing. Stem Cells 25:2739-2749 (Pubitemid 350127858)
5. Clevers H (2006) Wnt/beta-catenin signaling in development and disease. Cell 127:469-480 (Pubitemid 44647433)
6. Fiorina P, Jurewicz M, Augello A, Vergani A, Dada S, La Rosa S, Selig M, Godwin J, Law K, Placidi C, Smith RN, Capella C, Rodig S, Adra CN, Atkinson M, Sayegh MH, Abdi R (2009) Immunomodulatory function of bone marrow-derived mesenchymal stem cells in experimental autoimmune type 1 diabetes. J Immunol 183:993-1004
7. Fong DS, Aiello L, Gardner TW, King GL, Blankenship G, Cavallerano JD, Ferris FL 3rd, Klein R (2004) Retinopathy in diabetes. Diab Care 27(Suppl 1):S84-S87
8. Gardner TW, Antonetti DA, Barber AJ, LaNoue KF, Levison SW (2002) Diabetic retinopathy: more than meets the eye. Surv Ophthalmol 47(Suppl 2):S253-S262 (Pubitemid 36351245)
9. Grigoryan T, Wend P, Klaus A, Birchmeier W (2008) Deciphering the function of canonical Wnt signals in development and disease: conditional loss- and gain-of-function mutations of beta-catenin in mice. Genes Dev 22:2308-2341
10. Hari L, Brault V, Kleber M, Lee HY, Ille F, Leimeroth R, Paratore C, Suter U, Kemler R, Sommer L (2002) Lineage-specific requirements of beta-catenin in neural crest development. J Cell Biol 159:867-880 (Pubitemid 36008368)
11. Ho JH, Tseng TC, Ma WH, Ong WK, Chen YF, Chen MH, Lin MW, Hong CY, Lee OK (2012) Multiple intravenous transplantations of mesenchymal stem cells effectively restore long-term blood glucose homeostasis by hepatic engraftment and β-cell differentiation in streptozocin-induced diabetic mice. Cell Transplant 21:997-1009
12. Joksimovic M, Patel M, Taketo MM, Johnson R, Awatramani R (2012) Ectopic Wnt/beta-catenin signaling induces neurogenesis in the spinal cord and hindbrain floor plate. PLoS One 7:e30266
13. Kempen JH, O'Colmain BJ, Leske MC, Haffner SM, Klein R, Moss SE, Taylor HR, Hamman RF (2004) The prevalence of diabetic retinopathy among adults in the United States. Arch Ophthalmol 122:552-563 (Pubitemid 38456292)
14. Kondo T, Matsuoka AJ, Shimomura A, Koehler KR, Chan RJ, Miller JM, Srour EF, Hashino E (2011) Wnt signaling promotes neuronal differentiation from mesenchymal stem cells through activation of Tlx3. Stem Cells 29:836-846
15. Kuwabara T, Hsieh J, Muotri A, Yeo G, Warashina M, Lie DC, Moore L, Nakashima K, Asashima M, Gage FH (2009) Wnt-mediated activation of NeuroD1 and retro-elements during adult neurogenesis. Nat Neurosci 12:1097-1105
16. Lee HY, Kléber M, Hari L, Brault V, Suter U, Taketo MM, Kemler R, Sommer L (2004a) Instructive role of Wnt/beta-catenin in sensory fate specification in neural crest stem cells. Science 303:1020-1023 (Pubitemid 38209707)
17. Lee OK, Kuo TK, Chen WM, Lee KD, Hsieh SL, Chen TH (2004b) Isolation of multipotent mesenchymal stem cells from umbilical cord blood. Blood 103:1669-1675 (Pubitemid 38268958)
18. Li C, Xu Y, Jiang D, Hong W, Guo X, Wang P, Li W (2006) The expression of HIF-1 in the early diabetic NOD mice. Yan Ke Xue Bao 22:107-111
19. Li L, Xia Y, Wang Z, Cao X, Da Z, Guo G, Qian J, Liu X, Fan Y, Sun L, Sang A, Gu Z (2011) Suppression of the PI3K-Akt pathway is involved in the decreased adhesion and migration of bone marrow-derived mesenchymal stem cells from non-obese diabetic mice. Cell Biol Int 35:961-966
20. Ling L, Nurcombe V, Cool SM (2009) Wnt signaling controls the fate of mesenchymal stem cells. Gene 433:1-7
21. Logan CY, Nusse R (2004) The Wnt signaling pathway in development and disease. Annu Rev Cell Dev Biol 20:781-810 (Pubitemid 39488658)
22. Mori T, Kiyono T, Imabayashi H, Takeda Y, Tsuchiya K, Miyoshi S, Makino H, Matsumoto K, Saito H, Ogawa S, Sakamoto M, Hata J, Umezawa A (2005) Combination of hTERT and bmi-1, E6, or E7 induces prolongation of the life span of bone marrow stromal cells from an elderly donor without affecting their neurogenic potential. Mol Cell Biol 25:5183-5195 (Pubitemid 40781116)
23. Otero JJ, Fu W, Kan L, Cuadra AE, Kessler JA (2004) Beta-catenin signaling is required for neural differentiation of embryonic stem cells. Development 131:3545-3557 (Pubitemid 39199366)
24. Perin L, Giuliani S, Jin D, Sedrakyan S, Carraro G, Habibian R, Warburton D, Atala A, De Filippo RE (2007) Renal differentiation of amniotic fluid stem cells. Cell Prolif 40:936-948 (Pubitemid 350139201)
25. Pinto D, Clevers H (2005) Wnt control of stem cells and differentiation in the intestinal epithelium. Exp Cell Res 306:357-363 (Pubitemid 40732761)
26. Porada CD, Zanjani ED, Almeida-Porad G (2006) Adult mesenchymal stem cells: a pluripotent population with multiple applications. Curr Stem Cell Res Ther 1:365-369
27. Rada T, Reis RL, Gomes ME (2011) Distinct stem cells subpopulations isolated from human adipose tissue exhibit different chondrogenic and osteogenic differentiation potential. Stem Cell Rev Rep 7:64-76
28. Reya T, Clevers H (2005) Wnt signalling in stem cells and cancer. Nature 434:843-850 (Pubitemid 40558990)
29. Safford KM, Hicok KC, Safford SD, Halvorsen YD, Wilkison WO, Gimble JM, Rice HE (2002) Neurogenic differentiation of murine and human adipose-derived stromal cells. Biochem Biophys Res Commun 294:371-379 (Pubitemid 34694105)
30. Salero E, Hatten ME (2007) Differentiation of ES cells into cerebellar neurons. Proc Natl Acad Sci USA 104:2997-3002 (Pubitemid 46327992)
31. Sánchez-Sánchez AV, Camp E, Leal-Tassias A, Mullor JL (2010) Wnt signaling has different temporal roles during retinal development. Dev Dyn 239:297-310
32. Szanya V, Ermann J, Taylor C, Holness C, Fathman CG (2002) The subpopulation of CD4+ CD25+ splenocytes that delays adoptive transfer of diabetes expresses l-selectin and high levels of CCR7. J Immunol 169:2461-2465 (Pubitemid 34920990)
33. Toledo EM, Colombres M, Inestrosa NC (2008) Wnt signaling in neuroprotection and stem cell differentiation. Prog Neurobiol 86:281-296
34. Tomita M, Mori T, Maruyama K, Zahir T, Ward M, Umezawa A, Young MJ (2006) A comparison of neural differentiation and retinal transplantation with bone marrow-derived cells and retinal progenitor cells. Stem Cells 24:2270-2278 (Pubitemid 44527480)
35. Tsai PJ, Wang HS, Shyr YM, Weng ZC, Tai LC, Shyu JF, Chen TH (2012) Transplantation of insulin-producing cells from umbilical cord mesenchymal stem cells for the treatment of streptozotocin-induced diabetic rats. J Biomed Sci 30:19-47
36. Van Raay TJ, Moore KB, Iordanova I, Steele M, Jamrich M, Harris WA, Vetter ML (2005) Frizzled 5 signaling governs the neural potential of progenitors in the developing Xenopus retina. Neuron 46:23-36 (Pubitemid 40488309)
37. Volarevic V, Arsenijevic N, Lukic ML, Stojkovic M (2011) Concise review: mesenchymal stem cell treatment of the complications of diabetes mellitus. Stem Cells 29:5-10
38. Wang JF, Wang LJ, Wu YF, Xiang Y, Xie CG, Jia BB, Harrington J, McNiece IK (2004) Mesenchymal stem/progenitor cells in human umbilical cord blood as support for ex vivo expansion of CD34(+) hematopoietic stem cells and for chondrogenic differentiation. Haematologica 89:837-844 (Pubitemid 38981344)
39. Wei LC, Ding YX, Liu YH, Duan L, Bai Y, Shi M, Chen LW (2012) Low-dose radiation stimulates Wnt/beta-catenin signaling, neural stem cell proliferation and neurogenesis of the mouse hippocampus in vitro and in vivo. Curr Alzheimer Res 9:278-289
40. Yang Z, Li K, Yan X, Dong F, Zhao C (2010) Amelioration of diabetic retinopathy by engrafted human adipose-derived mesenchymal stem cells in streptozotocin diabetic rats. Graefes Arch Clin Exp Ophthalmol 248:1415-1422