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Volumn 27, Issue 4, 2013, Pages 337-342

A review of anti-inflammatory agents for symptoms of schizophrenia

Author keywords

aspirin; cytokines; Inflammation; minocycline; omega 3 fatty acids; schizophrenia

Indexed keywords

3ALPHA HYDROXY 5ALPHA PREGNAN 20 ONE; ACETYLSALICYLIC ACID; AMISULPRIDE; ANTIINFLAMMATORY AGENT; CELECOXIB; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITOR; DEXTROMETHORPHAN; DOCOSAHEXAENOIC ACID; DOPAMINE; GAMMA INTERFERON; ICOSAPENTAENOIC ACID; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MINOCYCLINE; NEUROSTEROID; NITRIC OXIDE SYNTHASE; OMEGA 3 FATTY ACID; PLACEBO; PRAVASTATIN; PREGNENOLONE; PROTEIN KINASE C ALPHA; PROTEIN KINASE C BETA; RISPERIDONE; SALSALATE; TUMOR NECROSIS FACTOR ALPHA;

EID: 84875701075     PISSN: 02698811     EISSN: 14617285     Source Type: Journal    
DOI: 10.1177/0269881112467089     Document Type: Review
Times cited : (88)

References (51)
  • 1
    • 78650510200 scopus 로고    scopus 로고
    • Targeting cyclooxygenases-1 and -2 in neuroinflammation: Therapeutic implications
    • Aid S, Bosetti F. Targeting cyclooxygenases-1 and -2 in neuroinflammation: Therapeutic implications. Biochimie. 2011 ; 93: 46-51
    • (2011) Biochimie , vol.93 , pp. 46-51
    • Aid, S.1    Bosetti, F.2
  • 2
    • 33846620518 scopus 로고    scopus 로고
    • Celecoxib as adjunctive therapy in schizophrenia: A double-blind, randomized and placebo-controlled trial
    • Akhondzadeh S, Tabatabaee M, Amini H, et al. Celecoxib as adjunctive therapy in schizophrenia: A double-blind, randomized and placebo-controlled trial. Schizophr Res. 2007 ; 90: 179-185
    • (2007) Schizophr Res , vol.90 , pp. 179-185
    • Akhondzadeh, S.1    Tabatabaee, M.2    Amini, H.3
  • 3
    • 76149102249 scopus 로고    scopus 로고
    • Long-chain omega-3 fatty acids for indicated prevention of psychotic disorders: A randomized, placebo-controlled trial
    • Amminger GP, Schafer MR, Papageorgiou K, et al. Long-chain omega-3 fatty acids for indicated prevention of psychotic disorders: A randomized, placebo-controlled trial. Arch Gen Psychiatry. 2010 ; 67: 146-154
    • (2010) Arch Gen Psychiatry , vol.67 , pp. 146-154
    • Amminger, G.P.1    Schafer, M.R.2    Papageorgiou, K.3
  • 4
    • 84857094629 scopus 로고    scopus 로고
    • Autoimmune diseases and severe infections as risk factors for schizophrenia: A 30-year population-based register study
    • Benros ME, Nielsen PRi, Nordentoft M, et al. Autoimmune diseases and severe infections as risk factors for schizophrenia: A 30-year population-based register study. Am J Psychiatry. 2011 ; 168: 1303-1310
    • (2011) Am J Psychiatry , vol.168 , pp. 1303-1310
    • Benros, M.E.1    Pri, N.2    Nordentoft, M.3
  • 5
    • 77649167678 scopus 로고    scopus 로고
    • Prenatal infection and schizophrenia: A review of epidemiologic and translational studies
    • Brown AS, Derkits EJ. Prenatal infection and schizophrenia: A review of epidemiologic and translational studies. Am J Psychiatry. 2010 ; 167: 261-280
    • (2010) Am J Psychiatry , vol.167 , pp. 261-280
    • Brown, A.S.1    Derkits, E.J.2
  • 6
    • 2442593823 scopus 로고    scopus 로고
    • Elevated maternal interleukin-8 levels and risk of schizophrenia in adult offspring
    • Brown AS, Hooton J, Schaefer CA, et al. Elevated maternal interleukin-8 levels and risk of schizophrenia in adult offspring. Am J Psychiatry. 2004 ; 161: 889-895
    • (2004) Am J Psychiatry , vol.161 , pp. 889-895
    • Brown, A.S.1    Hooton, J.2    Schaefer, C.A.3
  • 7
    • 2542553473 scopus 로고    scopus 로고
    • Dehydroepiandrosterone and allopregnanolone protect sympathoadrenal medulla cells against apoptosis via antiapoptotic Bcl-2 proteins
    • Charalampopoulos I, Tsatsanis C, Dermitzaki E, et al. Dehydroepiandrosterone and allopregnanolone protect sympathoadrenal medulla cells against apoptosis via antiapoptotic Bcl-2 proteins. Proc Natl Acad Sci U S A. 2004 ; 101: 8209-8214
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 8209-8214
    • Charalampopoulos, I.1    Tsatsanis, C.2    Dermitzaki, E.3
  • 8
    • 84864999825 scopus 로고    scopus 로고
    • Minocycline benefits negative symptoms in early schizophrenia; A randomised double-blind placebo-controlled clinical trial in patients on standard treatment
    • Chaudhry IB, Hallak J, Husain N, et al. Minocycline benefits negative symptoms in early schizophrenia; a randomised double-blind placebo-controlled clinical trial in patients on standard treatment. J Psychopharmacol. 2012 ; 26: 1185-1193
    • (2012) J Psychopharmacol , vol.26 , pp. 1185-1193
    • Chaudhry, I.B.1    Hallak, J.2    Husain, N.3
  • 9
    • 0036712807 scopus 로고    scopus 로고
    • Randomized, placebo-controlled study of ethyl-eicosapentaenoic acid as supplemental treatment in schizophrenia
    • Emsley R, Myburgh C, Oosthuizen P, et al. Randomized, placebo-controlled study of ethyl-eicosapentaenoic acid as supplemental treatment in schizophrenia. Am J Psychiatry. 2002 ; 159: 1596-1598
    • (2002) Am J Psychiatry , vol.159 , pp. 1596-1598
    • Emsley, R.1    Myburgh, C.2    Oosthuizen, P.3
  • 11
    • 0035190361 scopus 로고    scopus 로고
    • A placebo-controlled trial of omega-3 fatty acid (ethyl eicosapentaenoic acid) supplementation for residual symptoms and cognitive impairment in schizophrenia
    • Fenton WS, Dickerson F, Boronow J, et al. A placebo-controlled trial of omega-3 fatty acid (ethyl eicosapentaenoic acid) supplementation for residual symptoms and cognitive impairment in schizophrenia. Am J Psychiatry. 2001 ; 158: 2071-2074
    • (2001) Am J Psychiatry , vol.158 , pp. 2071-2074
    • Fenton, W.S.1    Dickerson, F.2    Boronow, J.3
  • 12
    • 22144454595 scopus 로고    scopus 로고
    • Minocycline attenuates T cell and microglia activity to impair cytokine production in T cell-microglia interaction
    • Giuliani F, Hader W, Yong VW. Minocycline attenuates T cell and microglia activity to impair cytokine production in T cell-microglia interaction. J Leukoc Biol. 2005 ; 78: 135-143
    • (2005) J Leukoc Biol , vol.78 , pp. 135-143
    • Giuliani, F.1    Hader, W.2    Yong, V.W.3
  • 13
    • 64149121817 scopus 로고    scopus 로고
    • Use of salsalate to target inflammation in the treatment of insulin resistance and type 2 diabetes
    • Goldfine AB, Silver R, Aldhahi W, et al. Use of salsalate to target inflammation in the treatment of insulin resistance and type 2 diabetes. Clin Transl Sci. 2008 ; 1: 36-43
    • (2008) Clin Transl Sci , vol.1 , pp. 36-43
    • Goldfine, A.B.1    Silver, R.2    Aldhahi, W.3
  • 14
    • 26444506864 scopus 로고    scopus 로고
    • Theories of schizophrenia: A genetic-inflammatory-vascular synthesis
    • Hanson DR, Gottesman II. Theories of schizophrenia: A genetic-inflammatory-vascular synthesis. BMC Med Genet. 2005 ; 6: 7
    • (2005) BMC Med Genet , vol.6 , pp. 7
    • Hanson, D.R.1    Gottesman, I.I.2
  • 15
    • 4544282704 scopus 로고    scopus 로고
    • Progesterone and allopregnanolone reduce inflammatory cytokines after traumatic brain injury
    • He J, Evans CO, Hoffman SW, et al. Progesterone and allopregnanolone reduce inflammatory cytokines after traumatic brain injury. Exp Neurol. 2004 ; 189: 404-412
    • (2004) Exp Neurol , vol.189 , pp. 404-412
    • He, J.1    Evans, C.O.2    Hoffman, S.W.3
  • 16
    • 84856513745 scopus 로고    scopus 로고
    • From the prodrome to chronic schizophrenia: The neurobiology underlying psychotic symptoms and cognitive impairments
    • Howes OD, Fusar-Poli P, Bloomfield M, et al. From the prodrome to chronic schizophrenia: The neurobiology underlying psychotic symptoms and cognitive impairments. Curr Pharm Des. 2012 ; 18: 459-465
    • (2012) Curr Pharm des , vol.18 , pp. 459-465
    • Howes, O.D.1    Fusar-Poli, P.2    Bloomfield, M.3
  • 17
    • 8744278883 scopus 로고    scopus 로고
    • Glutamate as a therapeutic target in psychiatric disorders
    • Javitt DC. Glutamate as a therapeutic target in psychiatric disorders. Mol Psychiatry. 2004 ; 9: 984-997
    • (2004) Mol Psychiatry , vol.9 , pp. 984-997
    • Javitt, D.C.1
  • 19
    • 81955168013 scopus 로고    scopus 로고
    • Adjunct minocycline to clozapine treated patients with persistent schizophrenia symptoms
    • Kelly DL, Vyas G, Richardson CM, et al. Adjunct minocycline to clozapine treated patients with persistent schizophrenia symptoms. Schizophr Res. 2011 ; 133: 257-258
    • (2011) Schizophr Res , vol.133 , pp. 257-258
    • Kelly, D.L.1    Vyas, G.2    Richardson, C.M.3
  • 21
    • 0029052144 scopus 로고
    • Progesterone synthesis and myelin formation by Schwann cells
    • Koenig HL, Schumacher M, Ferzaz B, et al. Progesterone synthesis and myelin formation by Schwann cells. Science. 1995 ; 268: 1500-1503
    • (1995) Science , vol.268 , pp. 1500-1503
    • Koenig, H.L.1    Schumacher, M.2    Ferzaz, B.3
  • 22
    • 77952641170 scopus 로고    scopus 로고
    • Adjuvant aspirin therapy reduces symptoms of schizophrenia spectrum disorders: Results from a randomized, double-blind, placebo-controlled trial
    • Laan W, Grobbee DE, Selten JP, et al. Adjuvant aspirin therapy reduces symptoms of schizophrenia spectrum disorders: Results from a randomized, double-blind, placebo-controlled trial. J Clin Psychiatry. 2010 ; 71: 520-527
    • (2010) J Clin Psychiatry , vol.71 , pp. 520-527
    • Laan, W.1    Grobbee, D.E.2    Selten, J.P.3
  • 23
    • 33646517061 scopus 로고    scopus 로고
    • Hypoxia-activated microglial mediators of neuronal survival are differentially regulated by tetracyclines
    • Lai AY, Todd KG. Hypoxia-activated microglial mediators of neuronal survival are differentially regulated by tetracyclines. Glia. 2006 ; 53: 809-816
    • (2006) Glia , vol.53 , pp. 809-816
    • Lai, A.Y.1    Todd, K.G.2
  • 24
    • 77649112679 scopus 로고    scopus 로고
    • A double-blind, randomized study of minocycline for the treatment of negative and cognitive symptoms in early-phase schizophrenia
    • Levkovitz Y, Mendlovich S, Riwkes S, et al. A double-blind, randomized study of minocycline for the treatment of negative and cognitive symptoms in early-phase schizophrenia. J Clin Psychiatry. 2010 ; 71: 138-149
    • (2010) J Clin Psychiatry , vol.71 , pp. 138-149
    • Levkovitz, Y.1    Mendlovich, S.2    Riwkes, S.3
  • 25
    • 16344374513 scopus 로고    scopus 로고
    • Femtomolar concentrations of dextromethorphan protect mesencephalic dopaminergic neurons from inflammatory damage
    • Li G, Cui G, Tzeng NS, et al. Femtomolar concentrations of dextromethorphan protect mesencephalic dopaminergic neurons from inflammatory damage. FASEB J. 2005 ; 19: 489-496
    • (2005) FASEB J , vol.19 , pp. 489-496
    • Li, G.1    Cui, G.2    Tzeng, N.S.3
  • 26
    • 0003495102 scopus 로고    scopus 로고
    • 2011) Protein synthesis inhibitors and miscellaneous antibacterial agents. In: ChabnerBABruntonLLKnollmanBC (eds) Goodman & Gilman's The Pharmacological Basis of Therapeutics. 12th ed. New York: McGraw-Hill. Chabner BA Brunton LL Knollman BC, ed. New York: McGraw-Hill;
    • MacDougall C Goodman & Gilman's The Pharmacological Basis of Therapeutics. 2011 ) Protein synthesis inhibitors and miscellaneous antibacterial agents. In: ChabnerBABruntonLLKnollmanBC (eds) Goodman & Gilman's The Pharmacological Basis of Therapeutics. 12th ed. New York: McGraw-Hill. Chabner BA Brunton LL Knollman BC, ed. New York: McGraw-Hill ; 2011 :
    • (2011) Goodman & Gilman's the Pharmacological Basis of Therapeutics
    • MacDougall, C.1
  • 27
    • 80052258839 scopus 로고    scopus 로고
    • Pregnenolone as a novel therapeutic candidate in schizophrenia: Emerging preclinical and clinical evidence
    • Marx CE, Bradford DW, Hamer RM, et al. Pregnenolone as a novel therapeutic candidate in schizophrenia: Emerging preclinical and clinical evidence. Neuroscience. 2011 ; 191: 78-90
    • (2011) Neuroscience , vol.191 , pp. 78-90
    • Marx, C.E.1    Bradford, D.W.2    Hamer, R.M.3
  • 28
    • 67449123074 scopus 로고    scopus 로고
    • Proof-of-concept trial with the neurosteroid pregnenolone targeting cognitive and negative symptoms in schizophrenia
    • Marx CE, Keefe RS, Buchanan RW, et al. Proof-of-concept trial with the neurosteroid pregnenolone targeting cognitive and negative symptoms in schizophrenia. Neuropsychopharmacology. 2009 ; 34: 1885-1903
    • (2009) Neuropsychopharmacology , vol.34 , pp. 1885-1903
    • Marx, C.E.1    Keefe, R.S.2    Buchanan, R.W.3
  • 29
    • 35848966767 scopus 로고    scopus 로고
    • Clozapine markedly elevates pregnenolone in rat hippocampus, cerebral cortex, and serum: Candidate mechanism for superior efficacy?
    • Marx CE, Shampine LJ, Duncan GE, et al. Clozapine markedly elevates pregnenolone in rat hippocampus, cerebral cortex, and serum: Candidate mechanism for superior efficacy?. Pharmacol Biochem Behav. 2006 ; 84: 598-608
    • (2006) Pharmacol Biochem Behav , vol.84 , pp. 598-608
    • Marx, C.E.1    Shampine, L.J.2    Duncan, G.E.3
  • 30
    • 80052853015 scopus 로고    scopus 로고
    • Meta-analysis of cytokine alterations in schizophrenia: Clinical status and antipsychotic effects
    • Miller BJ, Buckley P, Seabolt W, et al. Meta-analysis of cytokine alterations in schizophrenia: Clinical status and antipsychotic effects. Biol Psychiatry. 2011 ; 70: 663-671
    • (2011) Biol Psychiatry , vol.70 , pp. 663-671
    • Miller, B.J.1    Buckley, P.2    Seabolt, W.3
  • 31
    • 60549086674 scopus 로고    scopus 로고
    • Clinical potential of minocycline for schizophrenia
    • Miyaoka T. Clinical potential of minocycline for schizophrenia. CNS Neurol Disord Drug Targets. 2008 ; 7: 376-381
    • (2008) CNS Neurol Disord Drug Targets , vol.7 , pp. 376-381
    • Miyaoka, T.1
  • 32
    • 65649134782 scopus 로고    scopus 로고
    • Cytokines and schizophrenia: Microglia hypothesis of schizophrenia
    • Monji A, Kato T, Kanba S. Cytokines and schizophrenia: Microglia hypothesis of schizophrenia. Psychiatry Clin Neurosci. 2009 ; 63: 257-265
    • (2009) Psychiatry Clin Neurosci , vol.63 , pp. 257-265
    • Monji, A.1    Kato, T.2    Kanba, S.3
  • 33
    • 77955050321 scopus 로고    scopus 로고
    • Celecoxib treatment in an early stage of schizophrenia: Results of a randomized, double-blind, placebo-controlled trial of celecoxib augmentation of amisulpride treatment
    • Muller N, Krause D, Dehning S, et al. Celecoxib treatment in an early stage of schizophrenia: Results of a randomized, double-blind, placebo-controlled trial of celecoxib augmentation of amisulpride treatment. Schizophr Res. 2010 ; 121: 118-124
    • (2010) Schizophr Res , vol.121 , pp. 118-124
    • Muller, N.1    Krause, D.2    Dehning, S.3
  • 34
    • 0036272768 scopus 로고    scopus 로고
    • Beneficial antipsychotic effects of celecoxib add-on therapy compared to risperidone alone in schizophrenia
    • Muller N, Riedel M, Scheppach C, et al. Beneficial antipsychotic effects of celecoxib add-on therapy compared to risperidone alone in schizophrenia. Am J Psychiatry. 2002 ; 159: 1029-1034
    • (2002) Am J Psychiatry , vol.159 , pp. 1029-1034
    • Muller, N.1    Riedel, M.2    Scheppach, C.3
  • 35
    • 4344703065 scopus 로고    scopus 로고
    • COX-2 inhibition as a treatment approach in schizophrenia: Immunological considerations and clinical effects of celecoxib add-on therapy
    • Muller N, Ulmschneider M, Scheppach C, et al. COX-2 inhibition as a treatment approach in schizophrenia: Immunological considerations and clinical effects of celecoxib add-on therapy. Eur Arch Psychiatry Clin Neurosci. 2004 ; 254: 14-22
    • (2004) Eur Arch Psychiatry Clin Neurosci , vol.254 , pp. 14-22
    • Muller, N.1    Ulmschneider, M.2    Scheppach, C.3
  • 36
    • 34447540331 scopus 로고    scopus 로고
    • Minocycline down-regulates MHC II expression in microglia and macrophages through inhibition of IRF-1 and protein kinase C (PKC)alpha/betaII
    • Nikodemova M, Watters JJ, Jackson SJ, et al. Minocycline down-regulates MHC II expression in microglia and macrophages through inhibition of IRF-1 and protein kinase C (PKC)alpha/betaII. J Biol Chem. 2007 ; 282: 15208-15216
    • (2007) J Biol Chem , vol.282 , pp. 15208-15216
    • Nikodemova, M.1    Watters, J.J.2    Jackson, S.J.3
  • 37
    • 20544434987 scopus 로고    scopus 로고
    • Omega-3 fatty acids in the treatment of psychiatric disorders
    • Peet M, Stokes C.. Omega-3 fatty acids in the treatment of psychiatric disorders. Drugs. 2005 ; 65: 1051-1059
    • (2005) Drugs , vol.65 , pp. 1051-1059
    • Peet, M.1    Stokes, C.2
  • 38
    • 0035971559 scopus 로고    scopus 로고
    • Two double-blind placebo-controlled pilot studies of eicosapentaenoic acid in the treatment of schizophrenia
    • Peet M, Brind J, Ramchand CN, et al. Two double-blind placebo-controlled pilot studies of eicosapentaenoic acid in the treatment of schizophrenia. Schizophr Res. 2001 ; 49: 243-251
    • (2001) Schizophr Res , vol.49 , pp. 243-251
    • Peet, M.1    Brind, J.2    Ramchand, C.N.3
  • 39
    • 40949107708 scopus 로고    scopus 로고
    • Inflammatory cytokine alterations in schizophrenia: A systematic quantitative review
    • Potvin S, Stip E, Sepehry AA, et al. Inflammatory cytokine alterations in schizophrenia: A systematic quantitative review. Biol Psychiatry. 2008 ; 63: 801-808
    • (2008) Biol Psychiatry , vol.63 , pp. 801-808
    • Potvin, S.1    Stip, E.2    Sepehry, A.A.3
  • 40
    • 79960889350 scopus 로고    scopus 로고
    • Decreased glutathione levels and impaired antioxidant enzyme activities in drug-naive first-episode schizophrenic patients
    • Raffa M, Atig F, Mhalla A, et al. Decreased glutathione levels and impaired antioxidant enzyme activities in drug-naive first-episode schizophrenic patients. BMC Psychiatry. 2011 ; 11: 124
    • (2011) BMC Psychiatry , vol.11 , pp. 124
    • Raffa, M.1    Atig, F.2    Mhalla, A.3
  • 41
    • 20444405296 scopus 로고    scopus 로고
    • Celecoxib augmentation of continuously ill patients with schizophrenia
    • Rapaport MH, Delrahim KK, Bresee CJ, et al. Celecoxib augmentation of continuously ill patients with schizophrenia. Biol Psychiatry. 2005 ; 57: 1594-1596
    • (2005) Biol Psychiatry , vol.57 , pp. 1594-1596
    • Rapaport, M.H.1    Delrahim, K.K.2    Bresee, C.J.3
  • 42
    • 74549188501 scopus 로고    scopus 로고
    • Pregnenolone and dehydroepiandrosterone as an adjunctive treatment in schizophrenia and schizoaffective disorder: An 8-week, double-blind, randomized, controlled, 2-center, parallel-group trial
    • Ritsner MS, Gibel A, Shleifer T, et al. Pregnenolone and dehydroepiandrosterone as an adjunctive treatment in schizophrenia and schizoaffective disorder: An 8-week, double-blind, randomized, controlled, 2-center, parallel-group trial. J Clin Psychiatry. 2010 ; 71: 1351-1362
    • (2010) J Clin Psychiatry , vol.71 , pp. 1351-1362
    • Ritsner, M.S.1    Gibel, A.2    Shleifer, T.3
  • 43
    • 0035042767 scopus 로고    scopus 로고
    • The Th2-hypothesis of schizophrenia: A strategy to identify a subgroup of schizophrenia caused by immune mechanisms
    • Schwarz MJ, Muller N, Riedel M, et al. The Th2-hypothesis of schizophrenia: A strategy to identify a subgroup of schizophrenia caused by immune mechanisms. Med Hypotheses. 2001 ; 56: 483-486
    • (2001) Med Hypotheses , vol.56 , pp. 483-486
    • Schwarz, M.J.1    Muller, N.2    Riedel, M.3
  • 44
    • 56749173382 scopus 로고    scopus 로고
    • Systems approach with inflammatory exudates uncovers novel anti-inflammatory and pro-resolving mediators
    • Serhan CN. Systems approach with inflammatory exudates uncovers novel anti-inflammatory and pro-resolving mediators. Prostaglandins Leukot Essent Fatty Acids. 2008 ; 79: 157-163
    • (2008) Prostaglandins Leukot Essent Fatty Acids , vol.79 , pp. 157-163
    • Serhan, C.N.1
  • 45
    • 68449096727 scopus 로고    scopus 로고
    • Common variants on chromosome 6p22.1 are associated with schizophrenia
    • Shi J, Levinson DF, Duan J, et al. Common variants on chromosome 6p22.1 are associated with schizophrenia. Nature. 2009 ; 460: 753-757
    • (2009) Nature , vol.460 , pp. 753-757
    • Shi, J.1    Levinson, D.F.2    Duan, J.3
  • 46
    • 34247857663 scopus 로고    scopus 로고
    • Obesity, inflammation, and insulin resistance
    • Shoelson SE, Herrero L, Naaz A. Obesity, inflammation, and insulin resistance. Gastroenterology. 2007 ; 132: 2169-2180
    • (2007) Gastroenterology , vol.132 , pp. 2169-2180
    • Shoelson, S.E.1    Herrero, L.2    Naaz, A.3
  • 47
    • 0036931477 scopus 로고    scopus 로고
    • Omega-3 fatty acids in inflammation and autoimmune diseases
    • Simopoulos AP. Omega-3 fatty acids in inflammation and autoimmune diseases. J Am Coll Nutr. 2002 ; 21: 495-505
    • (2002) J Am Coll Nutr , vol.21 , pp. 495-505
    • Simopoulos, A.P.1
  • 48
    • 49949085933 scopus 로고    scopus 로고
    • Large recurrent microdeletions associated with schizophrenia
    • Stefansson H, Rujescu D, Cichon S, et al. Large recurrent microdeletions associated with schizophrenia. Nature. 2008 ; 455: 232-236
    • (2008) Nature , vol.455 , pp. 232-236
    • Stefansson, H.1    Rujescu, D.2    Cichon, S.3
  • 49
    • 0025995802 scopus 로고
    • Pregnenolone sulfate: A positive allosteric modulator at the N-methyl-D-aspartate receptor
    • Wu FS, Gibbs TT, Farb DH. Pregnenolone sulfate: A positive allosteric modulator at the N-methyl-D-aspartate receptor. Mol Pharmacol. 1991 ; 40: 333-336
    • (1991) Mol Pharmacol , vol.40 , pp. 333-336
    • Wu, F.S.1    Gibbs, T.T.2    Farb, D.H.3
  • 50
    • 3142636598 scopus 로고    scopus 로고
    • Effects of omega-3 fatty acid on platelet serotonin responsivity in patients with schizophrenia
    • Yao JK, Magan S, Sonel AF, et al. Effects of omega-3 fatty acid on platelet serotonin responsivity in patients with schizophrenia. Prostaglandins Leukot Essent Fatty Acids. 2004 ; 71: 171-176
    • (2004) Prostaglandins Leukot Essent Fatty Acids , vol.71 , pp. 171-176
    • Yao, J.K.1    Magan, S.2    Sonel, A.F.3
  • 51
    • 0032442475 scopus 로고    scopus 로고
    • Tetracyclines inhibit microglial activation and are neuroprotective in global brain ischemia
    • Yrjanheikki J, Keinanen R, Pellikka M, et al. Tetracyclines inhibit microglial activation and are neuroprotective in global brain ischemia. Proc Natl Acad Sci U S A. 1998 ; 95: 15769-15774
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 15769-15774
    • Yrjanheikki, J.1    Keinanen, R.2    Pellikka, M.3


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