-
1
-
-
33645666453
-
Homocysteine metabolism, hyperhomocysteinaemia and vascular disease: An overview
-
Castro R, Rivera I, Blom HJ, Jakobs C, Tavares de Almeida I. Homocysteine metabolism, hyperhomocysteinaemia and vascular disease: an overview. J Inherit Metab Dis. 2006;29:3-20.
-
(2006)
J Inherit Metab Dis.
, vol.29
, pp. 3-20
-
-
Castro, R.1
Rivera, I.2
Blom, H.J.3
Jakobs, C.4
Tavares de Almeida, I.5
-
3
-
-
0027392610
-
Vitamin B-12, vitamin B-6, and folate nutritional status in men with hyperhomocysteinemia
-
Ubbink JB, Vermaak WJ, van der Merwe A, Becker PJ. Vitamin B-12, vitamin B-6, and folate nutritional status in men with hyperhomocysteinemia. Am J Clin Nutr. 1993;57:47-53.
-
(1993)
Am J Clin Nutr.
, vol.57
, pp. 47-53
-
-
Ubbink, J.B.1
Vermaak, W.J.2
van der Merwe, A.3
Becker, P.J.4
-
4
-
-
0034706418
-
Hyperhomocysteinemia is associated with the presence of retinopathy in type 2 diabetes mellitus: The Hoorn study
-
Hoogeveen EK, Kostense PJ, Eysink PE, et al. Hyperhomocysteinemia is associated with the presence of retinopathy in type 2 diabetes mellitus: the Hoorn study. Arch Intern Med. 2000; 160:2984-2990.
-
(2000)
Arch Intern Med.
, vol.160
, pp. 2984-2990
-
-
Hoogeveen, E.K.1
Kostense, P.J.2
Eysink, P.E.3
-
5
-
-
0036156387
-
Homocysteine: A risk factor for retinal venous occlusive disease
-
Brown BA, Marx JL, Ward TP, et al. Homocysteine: a risk factor for retinal venous occlusive disease. Ophthalmology. 2002; 109:287-290.
-
(2002)
Ophthalmology.
, vol.109
, pp. 287-290
-
-
Brown, B.A.1
Marx, J.L.2
Ward, T.P.3
-
6
-
-
80053301456
-
The role of N-methyl-Daspartate receptor activation in homocysteine-induced death of retinal ganglion cells
-
Ganapathy PS, White RE, Ha Y, et al. The role of N-methyl-Daspartate receptor activation in homocysteine-induced death of retinal ganglion cells. Invest Ophthalmol Vis Sci. 2011;52: 5515-5524.
-
(2011)
Invest Ophthalmol Vis Sci.
, vol.52
, pp. 5515-5524
-
-
Ganapathy, P.S.1
White, R.E.2
Ha, Y.3
-
7
-
-
0036926376
-
Homocysteine and risk of open-angle glaucoma
-
Bleich S, Junemann A, von Ahsen N, et al. Homocysteine and risk of open-angle glaucoma. J Neural Transm. 2002;109: 1499-1504.
-
(2002)
J Neural Transm.
, vol.109
, pp. 1499-1504
-
-
Bleich, S.1
Junemann, A.2
von Ahsen, N.3
-
8
-
-
29544443447
-
Evaluation of plasma homocysteine and risk of age-related macular degeneration
-
Seddon JM, Gensler G, Klein ML, Milton RC. Evaluation of plasma homocysteine and risk of age-related macular degeneration. Am J Ophthalmol. 2006;141:201-203.
-
(2006)
Am J Ophthalmol.
, vol.141
, pp. 201-203
-
-
Seddon, J.M.1
Gensler, G.2
Klein, M.L.3
Milton, R.C.4
-
9
-
-
28244492862
-
Mechanisms of homocysteine-induced oxidative stress
-
Tyagi N, Sedoris KC, Steed M, Ovechkin AV, Moshal KS, Tyagi SC. Mechanisms of homocysteine-induced oxidative stress. Am J Physiol Heart Circ Physiol. 2005;289:H2649-2656.
-
(2005)
Am J Physiol Heart Circ Physiol.
, vol.289
-
-
Tyagi, N.1
Sedoris, K.C.2
Steed, M.3
Ovechkin, A.V.4
Moshal, K.S.5
Tyagi, S.C.6
-
10
-
-
0032480790
-
Hyperhomocysteinemia after an oral methionine load acutely impairs endothelial function in healthy adults
-
Bellamy MF, McDowell IF, Ramsey MW, et al. Hyperhomocysteinemia after an oral methionine load acutely impairs endothelial function in healthy adults. Circulation. 1998;98: 1848-1852.
-
(1998)
Circulation.
, vol.98
, pp. 1848-1852
-
-
Bellamy, M.F.1
McDowell, I.F.2
Ramsey, M.W.3
-
11
-
-
33745511931
-
Peroxisome proliferator-activated receptors in vascular biology-molecular mechanisms and clinical implications
-
Touyz RM, Schiffrin EL. Peroxisome proliferator-activated receptors in vascular biology-molecular mechanisms and clinical implications. Vascul Pharmacol. 2006;45:19-28.
-
(2006)
Vascul Pharmacol.
, vol.45
, pp. 19-28
-
-
Touyz, R.M.1
Schiffrin, E.L.2
-
12
-
-
70350433697
-
Disruption of endothelial peroxisome proliferator-activated receptor-gamma reduces vascular nitric oxide production
-
Kleinhenz JM, Kleinhenz DJ, You S, et al. Disruption of endothelial peroxisome proliferator-activated receptor-gamma reduces vascular nitric oxide production. Am J Physiol Heart Circ Physiol. 2009;297:H1647-1654.
-
(2009)
Am J Physiol Heart Circ Physiol.
, vol.297
-
-
Kleinhenz, J.M.1
Kleinhenz, D.J.2
You, S.3
-
13
-
-
77956467451
-
Synergism in hyperhomocysteinemia and diabetes: Role of PPAR gamma and tempol
-
Mishra PK, Tyagi N, Sen U, Joshua IG, Tyagi SC. Synergism in hyperhomocysteinemia and diabetes: role of PPAR gamma and tempol. Cardiovasc Diabetol. 2010;9:49.
-
(2010)
Cardiovasc Diabetol.
, vol.9
, pp. 49
-
-
Mishra, P.K.1
Tyagi, N.2
Sen, U.3
Joshua, I.G.4
Tyagi, S.C.5
-
14
-
-
0036783728
-
Peroxisome proliferators compete and ameliorate Hcy-mediated endocardial endothelial cell activation
-
Hunt MJ, Tyagi SC. Peroxisome proliferators compete and ameliorate Hcy-mediated endocardial endothelial cell activation. Am J Physiol Cell Physiol. 2002;283:C1073-1079.
-
(2002)
Am J Physiol Cell Physiol.
, vol.283
-
-
Hunt, M.J.1
Tyagi, S.C.2
-
15
-
-
80054789683
-
Pioglitazone, a peroxisome proliferator-activated receptor-{gamma} agonist, induces dilation of isolated porcine retinal arterioles: Role of nitric oxide and potassium channels
-
Omae T, Nagaoka T, Tanano I, Yoshida A. Pioglitazone, a peroxisome proliferator-activated receptor-{gamma} agonist, induces dilation of isolated porcine retinal arterioles: role of nitric oxide and potassium channels. Invest Ophthalmol Vis Sci. 2011;52:6749-6756.
-
(2011)
Invest Ophthalmol Vis Sci.
, vol.52
, pp. 6749-6756
-
-
Omae, T.1
Nagaoka, T.2
Tanano, I.3
Yoshida, A.4
-
16
-
-
45149096016
-
Rosiglitazone and delayed onset of proliferative diabetic retinopathy
-
Shen LQ, Child A, Weber GM, Folkman J, Aiello LP. Rosiglitazone and delayed onset of proliferative diabetic retinopathy. Arch Ophthalmol. 2008;126:793-799.
-
(2008)
Arch Ophthalmol.
, vol.126
, pp. 793-799
-
-
Shen, L.Q.1
Child, A.2
Weber, G.M.3
Folkman, J.4
Aiello, L.P.5
-
17
-
-
0346157985
-
Pioglitazone prevents hypertension and reduces oxidative stress in dietinduced obesity
-
Dobrian AD, Schriver SD, Khraibi AA, Prewitt RL. Pioglitazone prevents hypertension and reduces oxidative stress in dietinduced obesity. Hypertension. 2004;43:48-56.
-
(2004)
Hypertension.
, vol.43
, pp. 48-56
-
-
Dobrian, A.D.1
Schriver, S.D.2
Khraibi, A.A.3
Prewitt, R.L.4
-
18
-
-
0346122777
-
Pioglitazone inhibits LOX-1 expression in human coronary artery endothelial cells by reducing intracellular superoxide radical generation
-
Mehta JL, Hu B, Chen J, Li D. Pioglitazone inhibits LOX-1 expression in human coronary artery endothelial cells by reducing intracellular superoxide radical generation. Arterioscler Thromb Vasc Biol. 2003;23:2203-2208.
-
(2003)
Arterioscler Thromb Vasc Biol.
, vol.23
, pp. 2203-2208
-
-
Mehta, J.L.1
Hu, B.2
Chen, J.3
Li, D.4
-
19
-
-
22144432296
-
Requisite roles of A2A receptors, nitric oxide, and KATP channels in retinal arteriolar dilation in response to adenosine
-
Hein TW, Yuan Z, Rosa RH Jr, Kuo L. Requisite roles of A2A receptors, nitric oxide, and KATP channels in retinal arteriolar dilation in response to adenosine. Invest Ophthalmol Vis Sci. 2005;46:2113-2119.
-
(2005)
Invest Ophthalmol Vis Sci.
, vol.46
, pp. 2113-2119
-
-
Hein, T.W.1
Yuan, Z.2
Rosa Jr., R.H.3
Kuo, L.4
-
20
-
-
33644856900
-
Dilation of retinal arterioles in response to lactate: Role of nitric oxide, guanylyl cyclase, and ATP-sensitive potassium channels
-
Hein TW, Xu W, Kuo L. Dilation of retinal arterioles in response to lactate: role of nitric oxide, guanylyl cyclase, and ATP-sensitive potassium channels. Invest Ophthalmol Vis Sci. 2006;47:693-699.
-
(2006)
Invest Ophthalmol Vis Sci.
, vol.47
, pp. 693-699
-
-
Hein, T.W.1
Xu, W.2
Kuo, L.3
-
21
-
-
33847717468
-
Simvastatin elicits dilation of isolated porcine retinal arterioles: Role of nitric oxide and mevalonate-rho kinase pathways
-
Nagaoka T, Hein TW, Yoshida A, Kuo L. Simvastatin elicits dilation of isolated porcine retinal arterioles: role of nitric oxide and mevalonate-rho kinase pathways. Invest Ophthalmol Vis Sci. 2007;48:825-832.
-
(2007)
Invest Ophthalmol Vis Sci.
, vol.48
, pp. 825-832
-
-
Nagaoka, T.1
Hein, T.W.2
Yoshida, A.3
Kuo, L.4
-
22
-
-
0025047567
-
Endothelium-dependent, flowinduced dilation of isolated coronary arterioles
-
Kuo L, Davis MJ, Chilian WM. Endothelium-dependent, flowinduced dilation of isolated coronary arterioles. Am J Physiol. 1990;259:H1063-1070.
-
(1990)
Am J Physiol.
, vol.259
-
-
Kuo, L.1
Davis, M.J.2
Chilian, W.M.3
-
23
-
-
0036272886
-
Bradykinin relaxation in small porcine retinal arterioles
-
Jeppesen P, Aalkjaer C, Bek T. Bradykinin relaxation in small porcine retinal arterioles. Invest Ophthalmol Vis Sci. 2002;43: 1891-1896.
-
(2002)
Invest Ophthalmol Vis Sci.
, vol.43
, pp. 1891-1896
-
-
Jeppesen, P.1
Aalkjaer, C.2
Bek, T.3
-
24
-
-
0033961048
-
Homocysteine-induced inhibition of endothelium-dependent relaxation in rabbit aorta: Role for superoxide anions
-
Lang D, Kredan MB, Moat SJ, et al. Homocysteine-induced inhibition of endothelium-dependent relaxation in rabbit aorta: role for superoxide anions. Arterioscler Thromb Vasc Biol. 2000;20:422-427.
-
(2000)
Arterioscler Thromb Vasc Biol.
, vol.20
, pp. 422-427
-
-
Lang, D.1
Kredan, M.B.2
Moat, S.J.3
-
25
-
-
0037458932
-
Divergent roles of angiotensin II AT1 and AT2 receptors in modulating coronary microvascular function
-
Zhang C, Hein TW, Wang W, Kuo L. Divergent roles of angiotensin II AT1 and AT2 receptors in modulating coronary microvascular function. Circ Res. 2003;92:322-329.
-
(2003)
Circ Res.
, vol.92
, pp. 322-329
-
-
Zhang, C.1
Hein, T.W.2
Wang, W.3
Kuo, L.4
-
26
-
-
0037465438
-
Endothelin-1 increases vascular superoxide via endothelin(A)-NADPH oxidase pathway in lowrenin hypertension
-
Li L, Fink GD, Watts SW, et al. Endothelin-1 increases vascular superoxide via endothelin(A)-NADPH oxidase pathway in lowrenin hypertension. Circulation. 2003;107:1053-1058.
-
(2003)
Circulation.
, vol.107
, pp. 1053-1058
-
-
Li, L.1
Fink, G.D.2
Watts, S.W.3
-
27
-
-
0036719870
-
The non-diaryl heterocycle classes of p38 MAP kinase inhibitors
-
Cirillo PF, Pargellis C, Regan J. The non-diaryl heterocycle classes of p38 MAP kinase inhibitors. Curr Top Med Chem. 2002;2:1021-1035.
-
(2002)
Curr Top Med Chem.
, vol.2
, pp. 1021-1035
-
-
Cirillo, P.F.1
Pargellis, C.2
Regan, J.3
-
28
-
-
0035923665
-
SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase
-
Bennett BL, Sasaki DT, Murray BW, et al. SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase. Proc Natl Acad Sci U S A. 2001;98:13681-13686.
-
(2001)
Proc Natl Acad Sci U S A.
, vol.98
, pp. 13681-13686
-
-
Bennett, B.L.1
Sasaki, D.T.2
Murray, B.W.3
-
29
-
-
31344450173
-
Pioglitazone: A review of its use in type 2 diabetes mellitus
-
Waugh J, Keating GM, Plosker GL, Easthope S, Robinson DM. Pioglitazone: a review of its use in type 2 diabetes mellitus. Drugs. 2006;66:85-109.
-
(2006)
Drugs.
, vol.66
, pp. 85-109
-
-
Waugh, J.1
Keating, G.M.2
Plosker, G.L.3
Easthope, S.4
Robinson, D.M.5
-
30
-
-
11244253710
-
GW9662, a potent antagonist of PPARgamma, inhibits growth of breast tumour cells and promotes the anticancer effects of the PPARgamma agonist rosiglitazone, independently of PPARgamma activation
-
Seargent JM, Yates EA, Gill JH. GW9662, a potent antagonist of PPARgamma, inhibits growth of breast tumour cells and promotes the anticancer effects of the PPARgamma agonist rosiglitazone, independently of PPARgamma activation. Br J Pharmacol. 2004;143:933-937.
-
(2004)
Br J Pharmacol.
, vol.143
, pp. 933-937
-
-
Seargent, J.M.1
Yates, E.A.2
Gill, J.H.3
-
31
-
-
0009715206
-
Investigation of the inhibitory effects of homocysteine and copper on nitric oxide-mediated relaxation of rat isolated aorta
-
Emsley AM, Jeremy JY, Gomes GN, Angelini GD, Plane F. Investigation of the inhibitory effects of homocysteine and copper on nitric oxide-mediated relaxation of rat isolated aorta. Br J Pharmacol. 1999;126:1034-1040.
-
(1999)
Br J Pharmacol.
, vol.126
, pp. 1034-1040
-
-
Emsley, A.M.1
Jeremy, J.Y.2
Gomes, G.N.3
Angelini, G.D.4
Plane, F.5
-
32
-
-
4444367705
-
Poly(ADP-ribose) polymerase inhibition prevents homocysteine-induced endothelial dysfunction in the isolated rat aorta
-
Tasatargil A, Dalaklioglu S, Sadan G. Poly(ADP-ribose) polymerase inhibition prevents homocysteine-induced endothelial dysfunction in the isolated rat aorta. Pharmacology. 2004;72: 99-105.
-
(2004)
Pharmacology.
, vol.72
, pp. 99-105
-
-
Tasatargil, A.1
Dalaklioglu, S.2
Sadan, G.3
-
33
-
-
0141641147
-
Captopril restores endotheliumdependent relaxation of rat aortic rings after exposure to homocysteine
-
Fu YF, Xiong Y, Fu SH. Captopril restores endotheliumdependent relaxation of rat aortic rings after exposure to homocysteine. J Cardiovasc Pharmacol. 2003;42:566-572.
-
(2003)
J Cardiovasc Pharmacol.
, vol.42
, pp. 566-572
-
-
Fu, Y.F.1
Xiong, Y.2
Fu, S.H.3
-
34
-
-
34347397160
-
Homocysteine induces endothelial dysfunction via inhibition of arginine transport
-
Jin L, Caldwell RB, Li-Masters T, Caldwell RW. Homocysteine induces endothelial dysfunction via inhibition of arginine transport. J Physiol Pharmacol. 2007;58:191-206.
-
(2007)
J Physiol Pharmacol.
, vol.58
, pp. 191-206
-
-
Jin, L.1
Caldwell, R.B.2
Li-Masters, T.3
Caldwell, R.W.4
-
35
-
-
33846928244
-
Homocysteine-induced changes in vascular reactivity of guinea-pig pulmonary arteries: Role of the oxidative stress and poly(ADP-ribose) polymerase activation
-
Tasatargil A, Sadan G, Karasu E. Homocysteine-induced changes in vascular reactivity of guinea-pig pulmonary arteries: role of the oxidative stress and poly(ADP-ribose) polymerase activation. Pulm Pharmacol Ther. 2007;20:265-272.
-
(2007)
Pulm Pharmacol Ther.
, vol.20
, pp. 265-272
-
-
Tasatargil, A.1
Sadan, G.2
Karasu, E.3
-
36
-
-
0029885906
-
Both nitric oxide and prostaglandinmediated responses are impaired in skeletal muscle arterioles of hypertensive rats
-
Huang A, Koller A. Both nitric oxide and prostaglandinmediated responses are impaired in skeletal muscle arterioles of hypertensive rats. J Hypertens. 1996;14:887-895.
-
(1996)
J Hypertens.
, vol.14
, pp. 887-895
-
-
Huang, A.1
Koller, A.2
-
37
-
-
44649103514
-
C-reactive protein inhibits endothelium-dependent nitric oxide-mediated dilation of retinal arterioles via enhanced superoxide production
-
Nagaoka T, Kuo L, Ren Y, Yoshida A, Hein TW. C-reactive protein inhibits endothelium-dependent nitric oxide-mediated dilation of retinal arterioles via enhanced superoxide production. Invest Ophthalmol Vis Sci. 2008;49:2053-2060.
-
(2008)
Invest Ophthalmol Vis Sci.
, vol.49
, pp. 2053-2060
-
-
Nagaoka, T.1
Kuo, L.2
Ren, Y.3
Yoshida, A.4
Hein, T.W.5
-
38
-
-
0033679320
-
Effects of homocysteine on endothelial nitric oxide production
-
Zhang X, Li H, Jin H, Ebin Z, Brodsky S, Goligorsky MS. Effects of homocysteine on endothelial nitric oxide production. Am J Physiol Renal Physiol. 2000;279:F671-678.
-
(2000)
Am J Physiol Renal Physiol.
, vol.279
-
-
Zhang, X.1
Li, H.2
Jin, H.3
Ebin, Z.4
Brodsky, S.5
Goligorsky, M.S.6
-
39
-
-
1842411860
-
Homocyst(e)ine decreases bioavailable nitric oxide by a mechanism involving glutathione peroxidase
-
Upchurch GR Jr, Welch GN, Fabian AJ, et al. Homocyst(e)ine decreases bioavailable nitric oxide by a mechanism involving glutathione peroxidase. J Biol Chem. 1997;272:17012-17017.
-
(1997)
J Biol Chem.
, vol.272
, pp. 17012-17017
-
-
Upchurch Jr., G.R.1
Welch, G.N.2
Fabian, A.J.3
-
40
-
-
0032832961
-
Effect of homocysteine on the production of nitric oxide in endothelial cells
-
Chow K, Cheung F, Lao TT. Effect of homocysteine on the production of nitric oxide in endothelial cells. Clin Exp Pharmacol Physiol. 1999;26:817-818.
-
(1999)
Clin Exp Pharmacol Physiol.
, vol.26
, pp. 817-818
-
-
Chow, K.1
Cheung, F.2
Lao, T.T.3
-
41
-
-
0035923560
-
Homocysteine impairs the nitric oxide synthase pathway: Role of asymmetric dimethylarginine
-
Stuhlinger MC, Tsao PS, Her JH, Kimoto M, Balint RF, Cooke JP. Homocysteine impairs the nitric oxide synthase pathway: role of asymmetric dimethylarginine. Circulation. 2001;104:2569-2575.
-
(2001)
Circulation.
, vol.104
, pp. 2569-2575
-
-
Stuhlinger, M.C.1
Tsao, P.S.2
Her, J.H.3
Kimoto, M.4
Balint, R.F.5
Cooke, J.P.6
-
42
-
-
68549122963
-
Hyperhomocysteinemia and endothelial dysfunction
-
Cheng Z, Yang X, Wang H. Hyperhomocysteinemia and endothelial dysfunction. Curr Hypertens Rev. 2009;5:158-165.
-
(2009)
Curr Hypertens Rev.
, vol.5
, pp. 158-165
-
-
Cheng, Z.1
Yang, X.2
Wang, H.3
-
43
-
-
0347951237
-
Hyperhomocysteinemia activates nuclear factor-kappaB in endothelial cells via oxidative stress
-
Au-Yeung KK, Woo CW, Sung FL, Yip JC, Siow YL. Hyperhomocysteinemia activates nuclear factor-kappaB in endothelial cells via oxidative stress. Circ Res. 2004;94:28-36.
-
(2004)
Circ Res.
, vol.94
, pp. 28-36
-
-
Au-Yeung, K.K.1
Woo, C.W.2
Sung, F.L.3
Yip, J.C.4
Siow, Y.L.5
-
44
-
-
20044391979
-
Nitric oxide inhibition of homocysteine-induced human endothelial cell apoptosis by down-regulation of p53-dependent Noxa expression through the formation of S-nitrosohomocysteine
-
Lee SJ, Kim KM, Namkoong S, et al. Nitric oxide inhibition of homocysteine-induced human endothelial cell apoptosis by down-regulation of p53-dependent Noxa expression through the formation of S-nitrosohomocysteine. J Biol Chem. 2005; 280:5781-5788.
-
(2005)
J Biol Chem.
, vol.280
, pp. 5781-5788
-
-
Lee, S.J.1
Kim, K.M.2
Namkoong, S.3
-
45
-
-
14044276314
-
Mechanisms of increased vascular oxidant stress in hyperhomocysteinemia and its impact on endothelial function
-
Weiss N. Mechanisms of increased vascular oxidant stress in hyperhomocysteinemia and its impact on endothelial function. Curr Drug Metab. 2005;6:27-36.
-
(2005)
Curr Drug Metab.
, vol.6
, pp. 27-36
-
-
Weiss, N.1
-
46
-
-
38949198356
-
Homocysteine stimulates NADPH oxidase-mediated superoxide production leading to endothelial dysfunction in rats
-
Edirimanne VE, Woo CW, Siow YL, Pierce GN, Xie JY. Homocysteine stimulates NADPH oxidase-mediated superoxide production leading to endothelial dysfunction in rats. Can J Physiol Pharmacol. 2007;85:1236-1247.
-
(2007)
Can J Physiol Pharmacol.
, vol.85
, pp. 1236-1247
-
-
Edirimanne, V.E.1
Woo, C.W.2
Siow, Y.L.3
Pierce, G.N.4
Xie, J.Y.5
-
47
-
-
0022552919
-
Endothelial cell injury due to copper-catalyzed hydrogen peroxide generation from homocysteine
-
Starkebaum G, Harlan JM. Endothelial cell injury due to copper-catalyzed hydrogen peroxide generation from homocysteine. J Clin Invest. 1986;77:1370-1376.
-
(1986)
J Clin Invest.
, vol.77
, pp. 1370-1376
-
-
Starkebaum, G.1
Harlan, J.M.2
-
48
-
-
0142026209
-
p38 MAP kinases: Key signalling molecules as therapeutic targets for inflammatory diseases
-
Kumar S, Boehm J, Lee JC. p38 MAP kinases: key signalling molecules as therapeutic targets for inflammatory diseases. Nat Rev Drug Discov. 2003;2:717-726.
-
(2003)
Nat Rev Drug Discov.
, vol.2
, pp. 717-726
-
-
Kumar, S.1
Boehm, J.2
Lee, J.C.3
-
49
-
-
0038004740
-
Targeting JNK for therapeutic benefit: From junk to gold?
-
Manning AM, Davis RJ. Targeting JNK for therapeutic benefit: from junk to gold? Nat Rev Drug Discov. 2003;2:554-565.
-
(2003)
Nat Rev Drug Discov.
, vol.2
, pp. 554-565
-
-
Manning, A.M.1
Davis, R.J.2
-
50
-
-
70350641535
-
Atorvastatin attenuates homocysteineinduced apoptosis in human umbilical vein endothelial cells via inhibiting NADPH oxidase-related oxidative stress-triggered p38MAPK signaling
-
Bao XM, Wu CF, Lu GP. Atorvastatin attenuates homocysteineinduced apoptosis in human umbilical vein endothelial cells via inhibiting NADPH oxidase-related oxidative stress-triggered p38MAPK signaling. Acta Pharmacol Sin. 2009;30:1392-1398.
-
(2009)
Acta Pharmacol Sin.
, vol.30
, pp. 1392-1398
-
-
Bao, X.M.1
Wu, C.F.2
Lu, G.P.3
-
51
-
-
18544386508
-
Possible involvement of NADPH oxidase and JNK in homocysteine-induced oxidative stress and apoptosis in human umbilical vein endothelial cells
-
Dong F, Zhang X, Li SY, et al. Possible involvement of NADPH oxidase and JNK in homocysteine-induced oxidative stress and apoptosis in human umbilical vein endothelial cells. Cardiovasc Toxicol. 2005;5:9-20.
-
(2005)
Cardiovasc Toxicol.
, vol.5
, pp. 9-20
-
-
Dong, F.1
Zhang, X.2
Li, S.Y.3
-
52
-
-
0037214029
-
Hyperoxiainduced NAD(P)H oxidase activation and regulation by MAP kinases in human lung endothelial cells
-
Parinandi NL, Kleinberg MA, Usatyuk PV, et al. Hyperoxiainduced NAD(P)H oxidase activation and regulation by MAP kinases in human lung endothelial cells. Am J Physiol Lung Cell Mol Physiol. 2003;284:L26-38.
-
(2003)
Am J Physiol Lung Cell Mol Physiol.
, vol.284
-
-
Parinandi, N.L.1
Kleinberg, M.A.2
Usatyuk, P.V.3
-
53
-
-
83455230722
-
Effects of pioglitazone and metformin on vascular endothelial function in patients with type 2 diabetes treated with sulfonylureas
-
Naka KK, Papathanassiou K, Bechlioulis A, et al. Effects of pioglitazone and metformin on vascular endothelial function in patients with type 2 diabetes treated with sulfonylureas. Diab Vasc Dis Res. 2012;9:52-58.
-
(2012)
Diab Vasc Dis Res.
, vol.9
, pp. 52-58
-
-
Naka, K.K.1
Papathanassiou, K.2
Bechlioulis, A.3
-
54
-
-
33847684285
-
Mechanisms underlying the chronic pioglitazone treatment-induced improvement in the impaired endothelium-dependent relaxation seen in aortas from diabetic rats
-
Matsumoto T, Noguchi E, Kobayashi T, Kamata K. Mechanisms underlying the chronic pioglitazone treatment-induced improvement in the impaired endothelium-dependent relaxation seen in aortas from diabetic rats. Free Radic Biol Med. 2007; 42:993-1007.
-
(2007)
Free Radic Biol Med.
, vol.42
, pp. 993-1007
-
-
Matsumoto, T.1
Noguchi, E.2
Kobayashi, T.3
Kamata, K.4
-
55
-
-
33846818459
-
Basic mechanisms of oxidative stress and reactive oxygen species in cardiovascular injury
-
Papaharalambus CA, Griendling KK. Basic mechanisms of oxidative stress and reactive oxygen species in cardiovascular injury. Trends Cardiovasc Med. 2007;17:48-54.
-
(2007)
Trends Cardiovasc Med.
, vol.17
, pp. 48-54
-
-
Papaharalambus, C.A.1
Griendling, K.K.2
-
56
-
-
0033216629
-
NF-kappaB as a primary regulator of the stress response
-
Mercurio F, Manning AM. NF-kappaB as a primary regulator of the stress response. Oncogene. 1999;18:6163-6171.
-
(1999)
Oncogene.
, vol.18
, pp. 6163-6171
-
-
Mercurio, F.1
Manning, A.M.2
-
57
-
-
69549086770
-
Peroxisome proliferator-activated receptor-gamma ligands 15-deoxy-delta(12,14)-prostaglandin J2 and pioglitazone inhibit hydroxyl peroxide-induced TNFalpha and lipopolysaccharide-induced CXC chemokine expression in neonatal rat cardiac myocytes
-
Liu J, Xia Q, Zhang Q, et al. Peroxisome proliferator-activated receptor-gamma ligands 15-deoxy-delta(12,14)-prostaglandin J2 and pioglitazone inhibit hydroxyl peroxide-induced TNFalpha and lipopolysaccharide-induced CXC chemokine expression in neonatal rat cardiac myocytes. Shock. 2009;32: 317-324.
-
(2009)
Shock.
, vol.32
, pp. 317-324
-
-
Liu, J.1
Xia, Q.2
Zhang, Q.3
-
58
-
-
0023264984
-
Depletion of intracellular calcium stores by calcium ionophore A23187 induces the genes for glucose-regulated proteins in hamster fibroblasts
-
Drummond IA, Lee AS, Resendez E Jr, Steinhardt RA. Depletion of intracellular calcium stores by calcium ionophore A23187 induces the genes for glucose-regulated proteins in hamster fibroblasts. J Biol Chem. 1987;262:12801-12805.
-
(1987)
J Biol Chem.
, vol.262
, pp. 12801-12805
-
-
Drummond, I.A.1
Lee, A.S.2
Resendez Jr., E.3
Steinhardt, R.A.4
-
59
-
-
0034918799
-
Invited review: Arteriolar smooth muscle mechanotransduction: Ca(2{thorn}) signaling pathways underlying myogenic reactivity
-
Hill MA, Zou H, Potocnik SJ, Meininger GA, Davis MJ. Invited review: arteriolar smooth muscle mechanotransduction: Ca(2{thorn}) signaling pathways underlying myogenic reactivity. J Appl Physiol. 2001;91:973-983.
-
(2001)
J Appl Physiol.
, vol.91
, pp. 973-983
-
-
Hill, M.A.1
Zou, H.2
Potocnik, S.J.3
Meininger, G.A.4
Davis, M.J.5
-
60
-
-
0032499024
-
Homocysteine and atherothrombosis
-
Welch GN, Loscalzo J. Homocysteine and atherothrombosis. N Engl J Med. 1998;338:1042-1050.
-
(1998)
N Engl J Med.
, vol.338
, pp. 1042-1050
-
-
Welch, G.N.1
Loscalzo, J.2
-
61
-
-
0033004216
-
Serum total homocysteine concentrations in adolescent and adult Americans: Results from the third National Health and Nutrition Examination Survey
-
Jacques PF, Rosenberg IH, Rogers G, et al. Serum total homocysteine concentrations in adolescent and adult Americans: results from the third National Health and Nutrition Examination Survey. Am J Clin Nutr. 1999;69:482-489.
-
(1999)
Am J Clin Nutr.
, vol.69
, pp. 482-489
-
-
Jacques, P.F.1
Rosenberg, I.H.2
Rogers, G.3
-
62
-
-
0025756673
-
Hyperhomocysteinemia: An independent risk factor for vascular disease
-
Clarke R, Daly L, Robinson K, et al. Hyperhomocysteinemia: an independent risk factor for vascular disease. N Engl J Med. 1991;324:1149-1155.
-
(1991)
N Engl J Med.
, vol.324
, pp. 1149-1155
-
-
Clarke, R.1
Daly, L.2
Robinson, K.3
|