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Volumn 9, Issue , 2010, Pages

Synergism in hyperhomocysteinemia and diabetes: Role of PPAR gamma and tempol

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCHOLINE; CIGLITAZONE; CYSTATHIONINE BETA SYNTHASE; GELATINASE B; GLUCOSE; HOMOCYSTEINE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 4; TEMPOL; THIOREDOXIN; TISSUE INHIBITOR OF METALLOPROTEINASE 3; TISSUE INHIBITOR OF METALLOPROTEINASE 4; 2,4 THIAZOLIDINEDIONE DERIVATIVE; AMINE OXIDE; ANTIDIABETIC AGENT; ANTIOXIDANT; GELATINASE A; NOX4 PROTEIN, MOUSE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; TISSUE INHIBITOR OF METALLOPROTEINASE; TISSUE INHIBITOR OF METALLOPROTEINASE-4;

EID: 77956467451     PISSN: None     EISSN: 14752840     Source Type: Journal    
DOI: 10.1186/1475-2840-9-49     Document Type: Article
Times cited : (59)

References (68)
  • 1
    • 77950787113 scopus 로고    scopus 로고
    • Hyperhomocysteinemia and cardiovascular risk: effect of vitamin supplementation in risk reduction
    • 10.2174/157488410790410551, 20236081
    • Ciaccio M, Bellia C. Hyperhomocysteinemia and cardiovascular risk: effect of vitamin supplementation in risk reduction. Curr Clin Pharmacol 2010, 5:30-36. 10.2174/157488410790410551, 20236081.
    • (2010) Curr Clin Pharmacol , vol.5 , pp. 30-36
    • Ciaccio, M.1    Bellia, C.2
  • 2
    • 77949528932 scopus 로고    scopus 로고
    • [Vitamin treatments that lower homocysteine concentration: can they decrease cerebrovascular disease in primary prevention?]
    • Mendez-Gonzalez J, Rodriguez-Millan E, Julve J, Blanco-Vaca F. [Vitamin treatments that lower homocysteine concentration: can they decrease cerebrovascular disease in primary prevention?]. Rev Neurol 2010, 50:235-244.
    • (2010) Rev Neurol , vol.50 , pp. 235-244
    • Mendez-Gonzalez, J.1    Rodriguez-Millan, E.2    Julve, J.3    Blanco-Vaca, F.4
  • 3
    • 77955391743 scopus 로고    scopus 로고
    • Homocysteine and Hypertension in Diabetes: Does PPARgamma Have a Regulatory Role?
    • 2895301, 20613990
    • Sen U, Tyagi SC. Homocysteine and Hypertension in Diabetes: Does PPARgamma Have a Regulatory Role?. PPAR Res 2010, 2010:806538. 2895301, 20613990.
    • (2010) PPAR Res , vol.2010 , pp. 806538
    • Sen, U.1    Tyagi, S.C.2
  • 4
    • 0035198271 scopus 로고    scopus 로고
    • Homocysteine and cardiovascular disease in diabetes mellitus
    • 10.1016/S0021-9150(01)00531-7, 11730832
    • Audelin MC, Genest J. Homocysteine and cardiovascular disease in diabetes mellitus. Atherosclerosis 2001, 159:497-511. 10.1016/S0021-9150(01)00531-7, 11730832.
    • (2001) Atherosclerosis , vol.159 , pp. 497-511
    • Audelin, M.C.1    Genest, J.2
  • 5
    • 7944220064 scopus 로고    scopus 로고
    • Relationship of homocysteine with cardiovascular disease and blood pressure
    • 10.1111/j.1524-6175.2004.03643.x, 15365276
    • Dinavahi R, Falkner B. Relationship of homocysteine with cardiovascular disease and blood pressure. J Clin Hypertens (Greenwich) 2004, 6:494-498. 10.1111/j.1524-6175.2004.03643.x, 15365276.
    • (2004) J Clin Hypertens (Greenwich) , vol.6 , pp. 494-498
    • Dinavahi, R.1    Falkner, B.2
  • 6
    • 77956489908 scopus 로고    scopus 로고
    • Age, homocysteine, and oxidative stress: relation to hypertension and type 2 diabetes mellitus
    • Dominguez LJ, Galioto A, Pineo A, Ferlisi A, Ciaccio M, Putignano E, et al. Age, homocysteine, and oxidative stress: relation to hypertension and type 2 diabetes mellitus. J Am Coll Nutr 2010, 29:1-6.
    • (2010) J Am Coll Nutr , vol.29 , pp. 1-6
    • Dominguez, L.J.1    Galioto, A.2    Pineo, A.3    Ferlisi, A.4    Ciaccio, M.5    Putignano, E.6
  • 7
    • 0031964467 scopus 로고    scopus 로고
    • Hyperhomocysteinemia is associated with an increased risk of cardiovascular disease, especially in non-insulin-dependent diabetes mellitus: a population-based study
    • Hoogeveen EK, Kostense PJ, Beks PJ, Mackaay AJ, Jakobs C, Bouter LM, et al. Hyperhomocysteinemia is associated with an increased risk of cardiovascular disease, especially in non-insulin-dependent diabetes mellitus: a population-based study. Arterioscler Thromb Vasc Biol 1998, 18:133-138.
    • (1998) Arterioscler Thromb Vasc Biol , vol.18 , pp. 133-138
    • Hoogeveen, E.K.1    Kostense, P.J.2    Beks, P.J.3    Mackaay, A.J.4    Jakobs, C.5    Bouter, L.M.6
  • 8
    • 0034603841 scopus 로고    scopus 로고
    • Hyperhomocysteinemia increases risk of death, especially in type 2 diabetes: 5-year follow-up of the Hoorn Study
    • Hoogeveen EK, Kostense PJ, Jakobs C, Dekker JM, Nijpels G, Heine RJ, et al. Hyperhomocysteinemia increases risk of death, especially in type 2 diabetes: 5-year follow-up of the Hoorn Study. Circulation 2000, 101:1506-1511.
    • (2000) Circulation , vol.101 , pp. 1506-1511
    • Hoogeveen, E.K.1    Kostense, P.J.2    Jakobs, C.3    Dekker, J.M.4    Nijpels, G.5    Heine, R.J.6
  • 9
    • 0037164375 scopus 로고    scopus 로고
    • Homocysteine and cardiovascular disease: evidence on causality from a meta-analysis
    • 10.1136/bmj.325.7374.1202, 135491, 12446535
    • Wald DS, Law M, Morris JK. Homocysteine and cardiovascular disease: evidence on causality from a meta-analysis. BMJ 2002, 325:1202. 10.1136/bmj.325.7374.1202, 135491, 12446535.
    • (2002) BMJ , vol.325 , pp. 1202
    • Wald, D.S.1    Law, M.2    Morris, J.K.3
  • 10
    • 0033959411 scopus 로고    scopus 로고
    • Total homocysteine in patients with type 1 diabetes
    • 10.2337/diacare.23.1.84, 10857974
    • Pavia C, Ferrer I, Valls C, Artuch R, Colome C, Vilaseca MA. Total homocysteine in patients with type 1 diabetes. Diabetes Care 2000, 23:84-87. 10.2337/diacare.23.1.84, 10857974.
    • (2000) Diabetes Care , vol.23 , pp. 84-87
    • Pavia, C.1    Ferrer, I.2    Valls, C.3    Artuch, R.4    Colome, C.5    Vilaseca, M.A.6
  • 11
    • 0037164104 scopus 로고    scopus 로고
    • Homocysteine and risk of ischemic heart disease and stroke: a meta-analysis
    • 10.1001/jama.288.16.2015, 12387654
    • Homocysteine and risk of ischemic heart disease and stroke: a meta-analysis. JAMA 2002, 288:2015-2022. 10.1001/jama.288.16.2015, 12387654.
    • (2002) JAMA , vol.288 , pp. 2015-2022
  • 12
    • 18844438064 scopus 로고    scopus 로고
    • Extracellular matrix remodeling in the heart of the homocysteinemic obese rabbit
    • 10.1016/j.amjhyper.2004.11.035, 15882553
    • Carroll JF, Tyagi SC. Extracellular matrix remodeling in the heart of the homocysteinemic obese rabbit. Am J Hypertens 2005, 18:692-698. 10.1016/j.amjhyper.2004.11.035, 15882553.
    • (2005) Am J Hypertens , vol.18 , pp. 692-698
    • Carroll, J.F.1    Tyagi, S.C.2
  • 13
    • 53249144566 scopus 로고    scopus 로고
    • Effect of mast cell stabilizers in hyperhomocysteinemia-induced cardiac hypertrophy in rats
    • 10.1097/FJC.0b013e31817ae60f, 18520950
    • Singh AP, Singh M, Balakumar P. Effect of mast cell stabilizers in hyperhomocysteinemia-induced cardiac hypertrophy in rats. J Cardiovasc Pharmacol 2008, 51:596-604. 10.1097/FJC.0b013e31817ae60f, 18520950.
    • (2008) J Cardiovasc Pharmacol , vol.51 , pp. 596-604
    • Singh, A.P.1    Singh, M.2    Balakumar, P.3
  • 14
  • 15
    • 0343061035 scopus 로고    scopus 로고
    • Effect of pulmonary C-fibre afferent stimulation on cardiac vagal neurones in the nucleus ambiguus in anaesthetized cats
    • 10.1111/j.1469-7793.2000.t01-1-00157.x, 2269989, 10878108
    • Wang Y, Jones JF, Jeggo RD, de Burgh DM, Jordan D, Ramage AG. Effect of pulmonary C-fibre afferent stimulation on cardiac vagal neurones in the nucleus ambiguus in anaesthetized cats. J Physiol 2000, 526(Pt 1):157-165. 10.1111/j.1469-7793.2000.t01-1-00157.x, 2269989, 10878108.
    • (2000) J Physiol , vol.526 , Issue.PART 1 , pp. 157-165
    • Wang, Y.1    Jones, J.F.2    Jeggo, R.D.3    de Burgh, D.M.4    Jordan, D.5    Ramage, A.G.6
  • 16
    • 77952886659 scopus 로고    scopus 로고
    • Effects of maternal hyperhomocysteinemia induced by methionine intake on oxidative stress and apoptosis in pup rat brain
    • 10.1016/j.ijdevneu.2010.02.006, 20188811
    • Koz ST, Gouwy NT, Demir N, Nedzvetsky VS, Etem E, Baydas G. Effects of maternal hyperhomocysteinemia induced by methionine intake on oxidative stress and apoptosis in pup rat brain. Int J Dev Neurosci 2010, 28:325-329. 10.1016/j.ijdevneu.2010.02.006, 20188811.
    • (2010) Int J Dev Neurosci , vol.28 , pp. 325-329
    • Koz, S.T.1    Gouwy, N.T.2    Demir, N.3    Nedzvetsky, V.S.4    Etem, E.5    Baydas, G.6
  • 17
    • 76249084482 scopus 로고    scopus 로고
    • Homocystamides promote free-radical and oxidative damage to proteins
    • 10.1073/pnas.0909737107, 2818928, 20080717
    • Sibrian-Vazquez M, Escobedo JO, Lim S, Samoei GK, Strongin RM. Homocystamides promote free-radical and oxidative damage to proteins. Proc Natl Acad Sci USA 2010, 107:551-554. 10.1073/pnas.0909737107, 2818928, 20080717.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 551-554
    • Sibrian-Vazquez, M.1    Escobedo, J.O.2    Lim, S.3    Samoei, G.K.4    Strongin, R.M.5
  • 18
    • 33748559443 scopus 로고    scopus 로고
    • High glucose and homocysteine synergistically affect the metalloproteinases-tissue inhibitors of metalloproteinases pattern, but not TGFB expression, in human fibroblasts
    • 10.1007/s00125-006-0377-2, 16896935
    • Solini A, Santini E, Nannipieri M, Ferrannini E. High glucose and homocysteine synergistically affect the metalloproteinases-tissue inhibitors of metalloproteinases pattern, but not TGFB expression, in human fibroblasts. Diabetologia 2006, 49:2499-2506. 10.1007/s00125-006-0377-2, 16896935.
    • (2006) Diabetologia , vol.49 , pp. 2499-2506
    • Solini, A.1    Santini, E.2    Nannipieri, M.3    Ferrannini, E.4
  • 19
    • 33746476301 scopus 로고    scopus 로고
    • Effect of short-term folic acid supplementation on insulin sensitivity and inflammatory markers in overweight subjects
    • 10.1038/sj.ijo.0803265, 16491109
    • Solini A, Santini E, Ferrannini E. Effect of short-term folic acid supplementation on insulin sensitivity and inflammatory markers in overweight subjects. Int J Obes (Lond) 2006, 30:1197-1202. 10.1038/sj.ijo.0803265, 16491109.
    • (2006) Int J Obes (Lond) , vol.30 , pp. 1197-1202
    • Solini, A.1    Santini, E.2    Ferrannini, E.3
  • 20
    • 16644370461 scopus 로고    scopus 로고
    • Homocysteine induces metalloproteinase and shedding of beta-1 integrin in microvessel endothelial cells
    • 10.1002/jcb.20137, 15352177
    • Shastry S, Tyagi SC. Homocysteine induces metalloproteinase and shedding of beta-1 integrin in microvessel endothelial cells. J Cell Biochem 2004, 93:207-213. 10.1002/jcb.20137, 15352177.
    • (2004) J Cell Biochem , vol.93 , pp. 207-213
    • Shastry, S.1    Tyagi, S.C.2
  • 21
    • 49749148712 scopus 로고    scopus 로고
    • PPAR gamma agonist normalizes glomerular filtration rate, tissue levels of homocysteine, and attenuates endothelial-myocyte uncoupling in alloxan induced diabetic mice
    • 2500152, 18690293
    • Rodriguez WE, Sen U, Tyagi N, Kumar M, Carneal G, Aggrawal D, et al. PPAR gamma agonist normalizes glomerular filtration rate, tissue levels of homocysteine, and attenuates endothelial-myocyte uncoupling in alloxan induced diabetic mice. Int J Biol Sci 2008, 4:236-244. 2500152, 18690293.
    • (2008) Int J Biol Sci , vol.4 , pp. 236-244
    • Rodriguez, W.E.1    Sen, U.2    Tyagi, N.3    Kumar, M.4    Carneal, G.5    Aggrawal, D.6
  • 22
    • 0036818639 scopus 로고    scopus 로고
    • Metalloproteinase in myocardial adaptation and maladaptation
    • 10.1177/107424840200700407, 12490970
    • Tyagi SC, Hoit BD. Metalloproteinase in myocardial adaptation and maladaptation. J Cardiovasc Pharmacol Ther 2002, 7:241-246. 10.1177/107424840200700407, 12490970.
    • (2002) J Cardiovasc Pharmacol Ther , vol.7 , pp. 241-246
    • Tyagi, S.C.1    Hoit, B.D.2
  • 24
    • 0037372930 scopus 로고    scopus 로고
    • Insulin sensitivity and plasma homocysteine concentrations in non-diabetic obese and normal weight subjects
    • 10.1016/S0021-9150(02)00386-6, 12618274
    • Fonseca VA, Fink LM, Kern PA. Insulin sensitivity and plasma homocysteine concentrations in non-diabetic obese and normal weight subjects. Atherosclerosis 2003, 167:105-109. 10.1016/S0021-9150(02)00386-6, 12618274.
    • (2003) Atherosclerosis , vol.167 , pp. 105-109
    • Fonseca, V.A.1    Fink, L.M.2    Kern, P.A.3
  • 25
    • 72249100585 scopus 로고    scopus 로고
    • Type 1 diabetic cardiomyopathy in the Akita (Ins2WT/C96Y) mouse model is characterized by lipotoxicity and diastolic dysfunction with preserved systolic function
    • 10.1152/ajpheart.00452.2009, 19801494
    • Basu R, Oudit GY, Wang X, Zhang L, Ussher JR, Lopaschuk GD, et al. Type 1 diabetic cardiomyopathy in the Akita (Ins2WT/C96Y) mouse model is characterized by lipotoxicity and diastolic dysfunction with preserved systolic function. Am J Physiol Heart Circ Physiol 2009, 297:H2096-H2108. 10.1152/ajpheart.00452.2009, 19801494.
    • (2009) Am J Physiol Heart Circ Physiol , vol.297
    • Basu, R.1    Oudit, G.Y.2    Wang, X.3    Zhang, L.4    Ussher, J.R.5    Lopaschuk, G.D.6
  • 26
    • 77956194462 scopus 로고    scopus 로고
    • Cystathionine {gamma}-lyase-deficient mice require dietary cysteine to protect against acute lethal myopathy and oxidative injury
    • Epub 2010 Jun 21
    • Ishii I, Akahoshi N, Yamada H, Nakano S, Izumi T, Suematsu M. Cystathionine {gamma}-lyase-deficient mice require dietary cysteine to protect against acute lethal myopathy and oxidative injury. J Biol Chem 2010, 20;285(34):26358-68. Epub 2010 Jun 21.
    • (2010) J Biol Chem , vol.20-285 , Issue.34 , pp. 26358-26368
    • Ishii, I.1    Akahoshi, N.2    Yamada, H.3    Nakano, S.4    Izumi, T.5    Suematsu, M.6
  • 27
    • 77952260852 scopus 로고    scopus 로고
    • Hydrogen sulfide regulates homocysteine-mediated glomerulosclerosis
    • 10.1159/000296717, 20395677
    • Sen U, Munjal C, Qipshidze N, Abe O, Gargoum R, Tyagi SC. Hydrogen sulfide regulates homocysteine-mediated glomerulosclerosis. Am J Nephrol 2010, 31:442-455. 10.1159/000296717, 20395677.
    • (2010) Am J Nephrol , vol.31 , pp. 442-455
    • Sen, U.1    Munjal, C.2    Qipshidze, N.3    Abe, O.4    Gargoum, R.5    Tyagi, S.C.6
  • 28
    • 77954322333 scopus 로고    scopus 로고
    • Homocysteine, hydrogen sulfide (H2S) and NMDA-receptor in heart failure
    • Tyagi N, Mishra PK, Tyagi SC. Homocysteine, hydrogen sulfide (H2S) and NMDA-receptor in heart failure. Indian J Biochem Biophys 2009, 46:441-446.
    • (2009) Indian J Biochem Biophys , vol.46 , pp. 441-446
    • Tyagi, N.1    Mishra, P.K.2    Tyagi, S.C.3
  • 29
    • 77149155639 scopus 로고    scopus 로고
    • Hydrogen sulfide mitigates matrix metalloproteinase-9 activity and neurovascular permeability in hyperhomocysteinemic mice
    • 10.1016/j.neuint.2009.11.002, 19913585
    • Tyagi N, Givvimani S, Qipshidze N, Kundu S, Kapoor S, Vacek JC, et al. Hydrogen sulfide mitigates matrix metalloproteinase-9 activity and neurovascular permeability in hyperhomocysteinemic mice. Neurochem Int 2010, 56:301-307. 10.1016/j.neuint.2009.11.002, 19913585.
    • (2010) Neurochem Int , vol.56 , pp. 301-307
    • Tyagi, N.1    Givvimani, S.2    Qipshidze, N.3    Kundu, S.4    Kapoor, S.5    Vacek, J.C.6
  • 30
    • 2442671417 scopus 로고    scopus 로고
    • Metabolic syndrome and type 2 diabetes mellitus: focus on peroxisome proliferator activated receptors (PPAR)
    • 10.1186/1475-2840-2-4, 153546, 12834541
    • Tenenbaum A, Fisman EZ, Motro M. Metabolic syndrome and type 2 diabetes mellitus: focus on peroxisome proliferator activated receptors (PPAR). Cardiovasc Diabetol 2003, 2:4. 10.1186/1475-2840-2-4, 153546, 12834541.
    • (2003) Cardiovasc Diabetol , vol.2 , pp. 4
    • Tenenbaum, A.1    Fisman, E.Z.2    Motro, M.3
  • 31
    • 15444361805 scopus 로고    scopus 로고
    • Fatty acid oxidation inhibitors in the management of chronic complications of atherosclerosis
    • 10.1007/s11883-005-0077-2, 15683605
    • Folmes CD, Clanachan AS, Lopaschuk GD. Fatty acid oxidation inhibitors in the management of chronic complications of atherosclerosis. Curr Atheroscler Rep 2005, 7:63-70. 10.1007/s11883-005-0077-2, 15683605.
    • (2005) Curr Atheroscler Rep , vol.7 , pp. 63-70
    • Folmes, C.D.1    Clanachan, A.S.2    Lopaschuk, G.D.3
  • 32
    • 0032505096 scopus 로고    scopus 로고
    • Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor-gamma
    • 10.1038/25931, 9744270
    • Nolte RT, Wisely GB, Westin S, Cobb JE, Lambert MH, Kurokawa R, et al. Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor-gamma. Nature 1998, 395:137-143. 10.1038/25931, 9744270.
    • (1998) Nature , vol.395 , pp. 137-143
    • Nolte, R.T.1    Wisely, G.B.2    Westin, S.3    Cobb, J.E.4    Lambert, M.H.5    Kurokawa, R.6
  • 33
    • 0032993595 scopus 로고    scopus 로고
    • Hypertension and insulin resistance: role of peroxisome proliferator-activated receptor gamma
    • 10.1046/j.1440-1681.1999.03082.x, 10405788
    • Itoh H, Doi K, Tanaka T, Fukunaga Y, Hosoda K, Inoue G, et al. Hypertension and insulin resistance: role of peroxisome proliferator-activated receptor gamma. Clin Exp Pharmacol Physiol 1999, 26:558-560. 10.1046/j.1440-1681.1999.03082.x, 10405788.
    • (1999) Clin Exp Pharmacol Physiol , vol.26 , pp. 558-560
    • Itoh, H.1    Doi, K.2    Tanaka, T.3    Fukunaga, Y.4    Hosoda, K.5    Inoue, G.6
  • 34
    • 0035786908 scopus 로고    scopus 로고
    • Insulin resistance and its treatment by thiazolidinediones
    • 10.1210/rp.56.1.265, 11237217
    • Lebovitz HE, Banerji MA. Insulin resistance and its treatment by thiazolidinediones. Recent Prog Horm Res 2001, 56:265-294. 10.1210/rp.56.1.265, 11237217.
    • (2001) Recent Prog Horm Res , vol.56 , pp. 265-294
    • Lebovitz, H.E.1    Banerji, M.A.2
  • 35
    • 0031870652 scopus 로고    scopus 로고
    • Macrophages in human atheroma contain PPARgamma: differentiation-dependent peroxisomal proliferator-activated receptor gamma(PPARgamma) expression and reduction of MMP-9 activity through PPARgamma activation in mononuclear phagocytes in vitro
    • 1852950, 9665460
    • Marx N, Sukhova G, Murphy C, Libby P, Plutzky J. Macrophages in human atheroma contain PPARgamma: differentiation-dependent peroxisomal proliferator-activated receptor gamma(PPARgamma) expression and reduction of MMP-9 activity through PPARgamma activation in mononuclear phagocytes in vitro. Am J Pathol 1998, 153:17-23. 1852950, 9665460.
    • (1998) Am J Pathol , vol.153 , pp. 17-23
    • Marx, N.1    Sukhova, G.2    Murphy, C.3    Libby, P.4    Plutzky, J.5
  • 36
    • 0035089913 scopus 로고    scopus 로고
    • Fenofibrate raises plasma homocysteine levels in the fasted and fed states
    • 10.1016/S0021-9150(00)00584-0, 11254917
    • Bissonnette R, Treacy E, Rozen R, Boucher B, Cohn JS, Genest J. Fenofibrate raises plasma homocysteine levels in the fasted and fed states. Atherosclerosis 2001, 155:455-462. 10.1016/S0021-9150(00)00584-0, 11254917.
    • (2001) Atherosclerosis , vol.155 , pp. 455-462
    • Bissonnette, R.1    Treacy, E.2    Rozen, R.3    Boucher, B.4    Cohn, J.S.5    Genest, J.6
  • 37
    • 0023623394 scopus 로고
    • Comparative toxicity and safety profile of fenofibrate and other fibric acid derivatives
    • 10.1016/0002-9343(87)90868-0, 3318450
    • Blane GF. Comparative toxicity and safety profile of fenofibrate and other fibric acid derivatives. Am J Med 1987, 83:26-36. 10.1016/0002-9343(87)90868-0, 3318450.
    • (1987) Am J Med , vol.83 , pp. 26-36
    • Blane, G.F.1
  • 38
    • 0033578187 scopus 로고    scopus 로고
    • Serum homocysteine increases after therapy with fenofibrate or bezafibrate
    • 10.1016/S0140-6736(99)02153-4, 10421307
    • Dierkes J, Westphal S, Luley C. Serum homocysteine increases after therapy with fenofibrate or bezafibrate. Lancet 1999, 354:219-220. 10.1016/S0140-6736(99)02153-4, 10421307.
    • (1999) Lancet , vol.354 , pp. 219-220
    • Dierkes, J.1    Westphal, S.2    Luley, C.3
  • 39
    • 0033035462 scopus 로고    scopus 로고
    • Plasma homocysteine concentration related to diet, endothelial function and mononuclear cell gene expression among male hyperlipidaemic smokers
    • 10.1046/j.1365-2362.1999.00419.x, 10092996
    • Brude IR, Finstad HS, Seljeflot I, Drevon CA, Solvoll K, Sandstad B, et al. Plasma homocysteine concentration related to diet, endothelial function and mononuclear cell gene expression among male hyperlipidaemic smokers. Eur J Clin Invest 1999, 29:100-108. 10.1046/j.1365-2362.1999.00419.x, 10092996.
    • (1999) Eur J Clin Invest , vol.29 , pp. 100-108
    • Brude, I.R.1    Finstad, H.S.2    Seljeflot, I.3    Drevon, C.A.4    Solvoll, K.5    Sandstad, B.6
  • 40
    • 0033933236 scopus 로고    scopus 로고
    • Deactivation of peroxisome proliferator-activated receptor-alpha during cardiac hypertrophic growth
    • 10.1172/JCI9056, 378509, 10862787
    • Barger PM, Brandt JM, Leone TC, Weinheimer CJ, Kelly DP. Deactivation of peroxisome proliferator-activated receptor-alpha during cardiac hypertrophic growth. J Clin Invest 2000, 105:1723-1730. 10.1172/JCI9056, 378509, 10862787.
    • (2000) J Clin Invest , vol.105 , pp. 1723-1730
    • Barger, P.M.1    Brandt, J.M.2    Leone, T.C.3    Weinheimer, C.J.4    Kelly, D.P.5
  • 41
    • 0036783728 scopus 로고    scopus 로고
    • Peroxisome proliferators compete and ameliorate Hcy-mediated endocardial endothelial cell activation
    • Hunt MJ, Tyagi SC. Peroxisome proliferators compete and ameliorate Hcy-mediated endocardial endothelial cell activation. Am J Physiol Cell Physiol 2002, 283:C1073-C1079.
    • (2002) Am J Physiol Cell Physiol , vol.283
    • Hunt, M.J.1    Tyagi, S.C.2
  • 42
    • 0035797865 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma activators inhibit cardiac hypertrophy in cardiac myocytes
    • 10.1161/hc4001.097186, 11581147
    • Yamamoto K, Ohki R, Lee RT, Ikeda U, Shimada K. Peroxisome proliferator-activated receptor gamma activators inhibit cardiac hypertrophy in cardiac myocytes. Circulation 2001, 104:1670-1675. 10.1161/hc4001.097186, 11581147.
    • (2001) Circulation , vol.104 , pp. 1670-1675
    • Yamamoto, K.1    Ohki, R.2    Lee, R.T.3    Ikeda, U.4    Shimada, K.5
  • 43
    • 23944518894 scopus 로고    scopus 로고
    • Tempol therapy attenuates medial smooth muscle cell apoptosis and neointima formation after balloon catheter injury in carotid artery of diabetic rats
    • 10.1152/ajpheart.01071.2004, 15833798
    • Jagadeesha DK, Lindley TE, Deleon J, Sharma RV, Miller F, Bhalla RC. Tempol therapy attenuates medial smooth muscle cell apoptosis and neointima formation after balloon catheter injury in carotid artery of diabetic rats. Am J Physiol Heart Circ Physiol 2005, 289:H1047-H1053. 10.1152/ajpheart.01071.2004, 15833798.
    • (2005) Am J Physiol Heart Circ Physiol , vol.289
    • Jagadeesha, D.K.1    Lindley, T.E.2    Deleon, J.3    Sharma, R.V.4    Miller, F.5    Bhalla, R.C.6
  • 44
    • 32644459328 scopus 로고    scopus 로고
    • Effect of tempol on altered angiotensin II and acetylcholine-mediated vascular responses in thoracic aorta isolated from rats with insulin resistance
    • 10.1016/j.phrs.2005.11.002, 16412660
    • Viswanad B, Srinivasan K, Kaul CL, Ramarao P. Effect of tempol on altered angiotensin II and acetylcholine-mediated vascular responses in thoracic aorta isolated from rats with insulin resistance. Pharmacol Res 2006, 53:209-215. 10.1016/j.phrs.2005.11.002, 16412660.
    • (2006) Pharmacol Res , vol.53 , pp. 209-215
    • Viswanad, B.1    Srinivasan, K.2    Kaul, C.L.3    Ramarao, P.4
  • 45
    • 26844564082 scopus 로고    scopus 로고
    • Oxidative stress and the use of antioxidants in diabetes: linking basic science to clinical practice
    • 10.1186/1475-2840-4-5, 1131912, 15862133
    • Johansen JS, Harris AK, Rychly DJ, Ergul A. Oxidative stress and the use of antioxidants in diabetes: linking basic science to clinical practice. Cardiovasc Diabetol 2005, 4:5. 10.1186/1475-2840-4-5, 1131912, 15862133.
    • (2005) Cardiovasc Diabetol , vol.4 , pp. 5
    • Johansen, J.S.1    Harris, A.K.2    Rychly, D.J.3    Ergul, A.4
  • 46
    • 0028937163 scopus 로고
    • Mice deficient in cystathionine beta-synthase: animal models for mild and severe homocyst(e)inemia
    • 10.1073/pnas.92.5.1585, 42564, 7878023
    • Watanabe M, Osada J, Aratani Y, Kluckman K, Reddick R, Malinow MR, et al. Mice deficient in cystathionine beta-synthase: animal models for mild and severe homocyst(e)inemia. Proc Natl Acad Sci USA 1995, 92:1585-1589. 10.1073/pnas.92.5.1585, 42564, 7878023.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 1585-1589
    • Watanabe, M.1    Osada, J.2    Aratani, Y.3    Kluckman, K.4    Reddick, R.5    Malinow, M.R.6
  • 47
    • 18044389952 scopus 로고    scopus 로고
    • The cardioprotective effects of preconditioning with endotoxin, but not ischemia, are abolished by a peroxisome proliferator-activated receptor-gamma antagonist
    • 10.1124/jpet.104.080598, 15734901
    • Sivarajah A, McDonald MC, Thiemermann C. The cardioprotective effects of preconditioning with endotoxin, but not ischemia, are abolished by a peroxisome proliferator-activated receptor-gamma antagonist. J Pharmacol Exp Ther 2005, 313:896-901. 10.1124/jpet.104.080598, 15734901.
    • (2005) J Pharmacol Exp Ther , vol.313 , pp. 896-901
    • Sivarajah, A.1    McDonald, M.C.2    Thiemermann, C.3
  • 48
    • 17944401657 scopus 로고    scopus 로고
    • Ciprofibrate therapy improves endothelial function and reduces postprandial lipemia and oxidative stress in type 2 diabetes mellitus
    • Evans M, Anderson RA, Graham J, Ellis GR, Morris K, Davies S, et al. Ciprofibrate therapy improves endothelial function and reduces postprandial lipemia and oxidative stress in type 2 diabetes mellitus. Circulation 2000, 101:1773-1779.
    • (2000) Circulation , vol.101 , pp. 1773-1779
    • Evans, M.1    Anderson, R.A.2    Graham, J.3    Ellis, G.R.4    Morris, K.5    Davies, S.6
  • 49
    • 48749087487 scopus 로고    scopus 로고
    • Mitochondria, PPARs, and Cancer: Is Receptor-Independent Action of PPAR Agonists a Key?
    • 2464819, 18645611
    • Scatena R, Bottoni P, Giardina B. Mitochondria, PPARs, and Cancer: Is Receptor-Independent Action of PPAR Agonists a Key?. PPAR Res 2008, 2008:256251. 2464819, 18645611.
    • (2008) PPAR Res , vol.2008 , pp. 256251
    • Scatena, R.1    Bottoni, P.2    Giardina, B.3
  • 50
    • 33749584932 scopus 로고    scopus 로고
    • Differences in hepatotoxicity and gene expression profiles by anti-diabetic PPAR gamma agonists on rat primary hepatocytes and human HepG2 cells
    • 10.1007/s11030-006-9038-0, 17031537
    • Guo L, Zhang L, Sun Y, Muskhelishvili L, Blann E, Dial S, et al. Differences in hepatotoxicity and gene expression profiles by anti-diabetic PPAR gamma agonists on rat primary hepatocytes and human HepG2 cells. Mol Divers 2006, 10:349-360. 10.1007/s11030-006-9038-0, 17031537.
    • (2006) Mol Divers , vol.10 , pp. 349-360
    • Guo, L.1    Zhang, L.2    Sun, Y.3    Muskhelishvili, L.4    Blann, E.5    Dial, S.6
  • 51
    • 37149018726 scopus 로고    scopus 로고
    • Cystathionine-beta-synthase gene transfer and 3-deazaadenosine ameliorate inflammatory response in endothelial cells
    • 10.1152/ajpcell.00207.2007, 17855772
    • Sen U, Tyagi N, Kumar M, Moshal KS, Rodriguez WE, Tyagi SC. Cystathionine-beta-synthase gene transfer and 3-deazaadenosine ameliorate inflammatory response in endothelial cells. Am J Physiol Cell Physiol 2007, 293:C1779-C1787. 10.1152/ajpcell.00207.2007, 17855772.
    • (2007) Am J Physiol Cell Physiol , vol.293
    • Sen, U.1    Tyagi, N.2    Kumar, M.3    Moshal, K.S.4    Rodriguez, W.E.5    Tyagi, S.C.6
  • 52
    • 0033512105 scopus 로고    scopus 로고
    • Homocyst(e)ine impairs endocardial endothelial function
    • 10.1139/cjpp-77-12-950, 10606441
    • Tyagi SC, Smiley LM, Mujumdar VS. Homocyst(e)ine impairs endocardial endothelial function. Can J Physiol Pharmacol 1999, 77:950-957. 10.1139/cjpp-77-12-950, 10606441.
    • (1999) Can J Physiol Pharmacol , vol.77 , pp. 950-957
    • Tyagi, S.C.1    Smiley, L.M.2    Mujumdar, V.S.3
  • 53
    • 73349118462 scopus 로고    scopus 로고
    • MicroRNAs are involved in homocysteine-induced cardiac remodeling
    • 10.1007/s12013-009-9063-6, 2863043, 19669742
    • Mishra PK, Tyagi N, Kundu S, Tyagi SC. MicroRNAs are involved in homocysteine-induced cardiac remodeling. Cell Biochem Biophys 2009, 55:153-162. 10.1007/s12013-009-9063-6, 2863043, 19669742.
    • (2009) Cell Biochem Biophys , vol.55 , pp. 153-162
    • Mishra, P.K.1    Tyagi, N.2    Kundu, S.3    Tyagi, S.C.4
  • 54
    • 77649262569 scopus 로고    scopus 로고
    • Recessive mutations in the INS gene result in neonatal diabetes through reduced insulin biosynthesis
    • 10.1073/pnas.0910533107, 2840338, 20133622
    • Garin I, Edghill EL, Akerman I, Rubio-Cabezas O, Rica I, Locke JM, et al. Recessive mutations in the INS gene result in neonatal diabetes through reduced insulin biosynthesis. Proc Natl Acad Sci USA 2010, 107:3105-3110. 10.1073/pnas.0910533107, 2840338, 20133622.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 3105-3110
    • Garin, I.1    Edghill, E.L.2    Akerman, I.3    Rubio-Cabezas, O.4    Rica, I.5    Locke, J.M.6
  • 55
    • 37149019633 scopus 로고    scopus 로고
    • Nonobese, insulin-deficient Ins2Akita mice develop type 2 diabetes phenotypes including insulin resistance and cardiac remodeling
    • 10.1152/ajpendo.00256.2007, 17911348
    • Hong EG, Jung DY, Ko HJ, Zhang Z, Ma Z, Jun JY, et al. Nonobese, insulin-deficient Ins2Akita mice develop type 2 diabetes phenotypes including insulin resistance and cardiac remodeling. Am J Physiol Endocrinol Metab 2007, 293:E1687-E1696. 10.1152/ajpendo.00256.2007, 17911348.
    • (2007) Am J Physiol Endocrinol Metab , vol.293
    • Hong, E.G.1    Jung, D.Y.2    Ko, H.J.3    Zhang, Z.4    Ma, Z.5    Jun, J.Y.6
  • 57
    • 77749254756 scopus 로고    scopus 로고
    • Tumor necrosis factor induces matrix metalloproteinases in cardiomyocytes and cardiofibroblasts differentially via superoxide production in a PI3Kgamma-dependent manner
    • 10.1152/ajpcell.00351.2009, 20007453
    • Awad AE, Kandalam V, Chakrabarti S, Wang X, Penninger JM, Davidge ST, et al. Tumor necrosis factor induces matrix metalloproteinases in cardiomyocytes and cardiofibroblasts differentially via superoxide production in a PI3Kgamma-dependent manner. Am J Physiol Cell Physiol 2010, 298:C679-C692. 10.1152/ajpcell.00351.2009, 20007453.
    • (2010) Am J Physiol Cell Physiol , vol.298
    • Awad, A.E.1    Kandalam, V.2    Chakrabarti, S.3    Wang, X.4    Penninger, J.M.5    Davidge, S.T.6
  • 58
    • 74949098293 scopus 로고    scopus 로고
    • H2 S ameliorates oxidative and proteolytic stresses and protects the heart against adverse remodeling in chronic heart failure
    • 10.1152/ajpheart.00682.2009, 19933416
    • Mishra PK, Tyagi N, Sen U, Givvimani S, Tyagi SC. H2 S ameliorates oxidative and proteolytic stresses and protects the heart against adverse remodeling in chronic heart failure. Am J Physiol Heart Circ Physiol 2010, 298:H451-H456. 10.1152/ajpheart.00682.2009, 19933416.
    • (2010) Am J Physiol Heart Circ Physiol , vol.298
    • Mishra, P.K.1    Tyagi, N.2    Sen, U.3    Givvimani, S.4    Tyagi, S.C.5
  • 59
    • 77954280531 scopus 로고    scopus 로고
    • Angiotensin II enhances interleukin-1 beta-induced MMP-9 secretion in adult rat cardiac fibroblasts
    • 10.1292/jvms.09-0582, 20145375
    • Okada M, Yamawaki H, Hara Y. Angiotensin II enhances interleukin-1 beta-induced MMP-9 secretion in adult rat cardiac fibroblasts. J Vet Med Sci 2010, 72:735-739. 10.1292/jvms.09-0582, 20145375.
    • (2010) J Vet Med Sci , vol.72 , pp. 735-739
    • Okada, M.1    Yamawaki, H.2    Hara, Y.3
  • 61
    • 77952958509 scopus 로고    scopus 로고
    • Filling pressures and collagen metabolism in hypertensive patients with heart failure and normal ejection fraction
    • 10.1161/HYPERTENSIONAHA.109.149112, 20404218
    • Gonzalez A, Lopez B, Querejeta R, Zubillaga E, Echeverria T, Diez J. Filling pressures and collagen metabolism in hypertensive patients with heart failure and normal ejection fraction. Hypertension 2010, 55:1418-1424. 10.1161/HYPERTENSIONAHA.109.149112, 20404218.
    • (2010) Hypertension , vol.55 , pp. 1418-1424
    • Gonzalez, A.1    Lopez, B.2    Querejeta, R.3    Zubillaga, E.4    Echeverria, T.5    Diez, J.6
  • 63
    • 51649101109 scopus 로고    scopus 로고
    • Low tissue inhibitor of metalloproteinases 3 and high matrix metalloproteinase 14 levels defines a subpopulation of highly invasive foam-cell macrophages
    • 10.1161/ATVBAHA.108.170548, 2851011, 18566294
    • Johnson JL, Sala-Newby GB, Ismail Y, Aguilera CM, Newby AC. Low tissue inhibitor of metalloproteinases 3 and high matrix metalloproteinase 14 levels defines a subpopulation of highly invasive foam-cell macrophages. Arterioscler Thromb Vasc Biol 2008, 28:1647-1653. 10.1161/ATVBAHA.108.170548, 2851011, 18566294.
    • (2008) Arterioscler Thromb Vasc Biol , vol.28 , pp. 1647-1653
    • Johnson, J.L.1    Sala-Newby, G.B.2    Ismail, Y.3    Aguilera, C.M.4    Newby, A.C.5
  • 64
    • 0034619027 scopus 로고    scopus 로고
    • Secondary prevention with antioxidants of cardiovascular disease in endstage renal disease (SPACE): randomised placebo-controlled trial
    • 10.1016/S0140-6736(00)02783-5, 11072938
    • Boaz M, Smetana S, Weinstein T, Matas Z, Gafter U, Iaina A, et al. Secondary prevention with antioxidants of cardiovascular disease in endstage renal disease (SPACE): randomised placebo-controlled trial. Lancet 2000, 356:1213-1218. 10.1016/S0140-6736(00)02783-5, 11072938.
    • (2000) Lancet , vol.356 , pp. 1213-1218
    • Boaz, M.1    Smetana, S.2    Weinstein, T.3    Matas, Z.4    Gafter, U.5    Iaina, A.6
  • 65
    • 34548361214 scopus 로고    scopus 로고
    • Differential effects of an anti-oxidant intervention on cardiomyocyte expression of adrenomedullin and intermedin and their receptor components in chronic nitric oxide deficiency
    • 10.1159/000107513, 17762156
    • Bell D, Zhao Y, McCoy FP, Devine AB, McDermott BJ. Differential effects of an anti-oxidant intervention on cardiomyocyte expression of adrenomedullin and intermedin and their receptor components in chronic nitric oxide deficiency. Cell Physiol Biochem 2007, 20:269-282. 10.1159/000107513, 17762156.
    • (2007) Cell Physiol Biochem , vol.20 , pp. 269-282
    • Bell, D.1    Zhao, Y.2    McCoy, F.P.3    Devine, A.B.4    McDermott, B.J.5
  • 66
    • 0030808443 scopus 로고    scopus 로고
    • Tempol inhibits neutrophil and hydrogen peroxide-mediated DNA damage
    • 10.1016/S0891-5849(97)00079-8, 9378367
    • Hahn SM, Mitchell JB, Shacter E. Tempol inhibits neutrophil and hydrogen peroxide-mediated DNA damage. Free Radic Biol Med 1997, 23:879-884. 10.1016/S0891-5849(97)00079-8, 9378367.
    • (1997) Free Radic Biol Med , vol.23 , pp. 879-884
    • Hahn, S.M.1    Mitchell, J.B.2    Shacter, E.3
  • 67
    • 77956701448 scopus 로고    scopus 로고
    • Short-term calorie restriction reverses vascular endothelial dysfunction in old mice by increasing nitric oxide and reducing oxidative stress
    • 10.1111/j.1474-9726.2010.00557.x, 20121721
    • Rippe C, Lesniewski L, Connell M, LaRocca T, Donato A, Seals D. Short-term calorie restriction reverses vascular endothelial dysfunction in old mice by increasing nitric oxide and reducing oxidative stress. Aging Cell 2010, 9:304-312. 10.1111/j.1474-9726.2010.00557.x, 20121721.
    • (2010) Aging Cell , vol.9 , pp. 304-312
    • Rippe, C.1    Lesniewski, L.2    Connell, M.3    LaRocca, T.4    Donato, A.5    Seals, D.6
  • 68
    • 0042991271 scopus 로고    scopus 로고
    • The anti-oxidant Tempol reverses and partially prevents adrenocorticotrophic hormone-induced hypertension in the rat
    • 10.1097/00004872-200308000-00015, 12872045
    • Zhang Y, Jang R, Mori TA, Croft KD, Schyvens CG, McKenzie KU, et al. The anti-oxidant Tempol reverses and partially prevents adrenocorticotrophic hormone-induced hypertension in the rat. J Hypertens 2003, 21:1513-1518. 10.1097/00004872-200308000-00015, 12872045.
    • (2003) J Hypertens , vol.21 , pp. 1513-1518
    • Zhang, Y.1    Jang, R.2    Mori, T.A.3    Croft, K.D.4    Schyvens, C.G.5    McKenzie, K.U.6


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