Mechanisms of compensatory renal growth

Pediatric Endocrinology Reviews

Volumn 10, Issue 1, 2012, Pages 152-163

  Cleper, Roxana ^a  

^a TEL AVIV UNIVERSITY   (Israel)

Author keywords

Compensatory Renal Growth; GH IGF1; Hypertrophy; Kidney; MTOR; Nephrogenesis; Obesity; Prematurity; TGF b1

Indexed keywords

EPIDERMAL GROWTH FACTOR; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; MAMMALIAN TARGET OF RAPAMYCIN; REACTIVE OXYGEN METABOLITE; SCATTER FACTOR; SOMATOMEDIN C; TRANSFORMING GROWTH FACTOR BETA1; VASCULOTROPIN; SIGNAL PEPTIDE;

AGING; BECKWITH WIEDEMANN SYNDROME; CELL ACTIVATION; DIABETES MELLITUS; EMBRYOLOGY; GESTATIONAL AGE; GLOMERULUS FILTRATION RATE; HUMAN; INSULIN CLEARANCE; KIDNEY BIOPSY; KIDNEY DEVELOPMENT; KIDNEY DYSPLASIA; KIDNEY HYPERTROPHY; KIDNEY HYPOPLASIA; KIDNEY SIZE; KIDNEY TUMOR; LOW BIRTH WEIGHT; MULTICYSTIC DYSPLASTIC KIDNEY; NONHUMAN; OBESITY; PERINATAL ASPHYXIA; PREMATURE LABOR; REVIEW; SHORT STATURE; SIGNAL TRANSDUCTION; SOLITARY KIDNEY; SOTOS SYNDROME; ULTRASOUND; UNINEPHRECTOMY; ANIMAL; CONGENITAL MALFORMATION; DISEASE MODEL; FEMALE; FOLLOW UP; GLOMERULUS; GROWTH, DEVELOPMENT AND AGING; HYPERTROPHY; KIDNEY; KIDNEY TUBULE; MOUSE; NEWBORN; PATHOLOGY; PHYSIOLOGY; PREGNANCY; PRENATAL DEVELOPMENT; PROGNOSIS;

ANIMALS; DISEASE MODELS, ANIMAL; FEMALE; FOLLOW-UP STUDIES; HUMANS; HYPERTROPHY; INFANT, NEWBORN; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; KIDNEY; KIDNEY GLOMERULUS; KIDNEY TUBULES; MICE; MULTICYSTIC DYSPLASTIC KIDNEY; PREGNANCY; PROGNOSIS;

MLCS; MLOWN;

EID: 84875620959     PISSN: 15654753     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (123)

1. Taal MW, Brenner BM. Adaptation to nephron loss and mechanisms of progression in chronic kidney disease. ln:Taal MW, Chertow GM, Marsden PA, Skorecki K, Yu ASL, Brenner BM, eds. Brenner and Rector's The Kidney, 9th edition, Philadelphia: WB Saunders, 2011; 1919-1971
2. Fine L. The biology of renal hypertrophy. Kidney Int 1986; 29:619-634
3. Kerecuk L, Schreuder MF, Woolf AS. Renal tract malformations: perspectives for nephrologists. Nat ClinPract Nephrol 2008; 4:312-325
4. Bauer SB. Anomalies of the upper urinary tract. In:Wein AJ, Kavoussi LR, Novick AC, Partin AW, Peters CA, eds. Campbell-Walsh Urology, 9thedition. Philadelphia: WB Saunders, 2007; 3269-3304
5. Wesson LG. Compensatory growth and other growth responses of the kidney. Nephron 1989; 51:149-184
6. Brenner BM, Lawler EV, Mackenzie HS. The hyperfiltration theory: a paradigm shift in nephrology. Kidney Int 1996; 49:1774-1777
7. Hostteter TH, Olson JL, Rennke HG, Venkatachalam MA, Brenner BM. Hyperfiltration in remnant nephrons: a potentially adverse response to renal ablation. Am J Physiol 1981; 241:F85-F93
8. Rosenblum ND. Developmental biology of the human kidney. Semin Fetal Neonatal Med 2008; 13:125-132
9. Bertram JF, Douglas-Denton RN, Diouf B, Hughson MD, Hoy WE. Human nephron number: implications for health and disease. Pediatr Nephrol 2011; 26:1529-1533
10. Abitbol CL, Ingelfingeer Jr. Nephron mass and cardiovascular and renal disease risks. Semin Nephrol 2009; 29:445-454
11. Luyckx VA, Brenner BM. The clinical importance of nephron mass. J Am Soc Nephrol 2010; 21:898-910
12. Douglas- Denton R, Moritz KM, Bertram JF, Wintour EM. Compensatory renal growth after unilateral nephrectomy in the ovine fetus. J Am Soc Nephrol 2002; 13:406-410
13. Maluf NS. On the enlargement of the normal congenitally solitary kidney. Br J Urol1997; 79:836-841
14. Goodyer P. Renal dysplasia/hypoplasia. In: Avner ED, Harmon WE, Niaudet P, Yoshikawa N, editors. Pediatric Nephrology, 6th edition. Berlin, Heidelberg: Springer-Verlag, 2009; 107-120
15. Davidson AJ. Uncharted waters: nephrogenesis and renal regeneration in fish and mammals. Pediatr Nephrol 2011; 26:1435-1443
16. Kaneyama K, Yamataka A, Satake S, Yanai T, Lane GJ, Kaneko K, Yamashiro Y, Miyano T. Associated urologic anomalies in children with solitary kidney. J Pediatr Surg 2004; 39:85-87
17. Woolf AS, Hillman KA. Unilateral renal agenesis and the congenital solitary functioning kidney: developmental, genetic and clinical perspectives. BJU Int 2006; 99:17-21
18. Shapiro E, Goldfarb DA, Ritchey ML. The congenital and acquired solitary kidney. Rev Urol 2003; 5:2-8
19. Warady BA, Chadha V. Chronic kidney disease in children: the global perspective. Pediatr Nephrol2007; 22:1999-2009
20. Schreuder MF, Westland R, van Wijk JE. Unilateral multicystic dysplastic kidney: a meta-analysis of observational studies on the incidence of associated urinary tract malformations and the contralateral kidney. Nephrol Dial Transplant 2009; 24:1810-1818
21. Hains DS, Bats CM, Ingraham S, Schwaderer AL. Management and etiology of the unilateral multicystic dysplastic kidney: a review. Pediatr Nephrol 2009; 24:233-241
22. Foster SV, Hawkins EP. Deficient metanephric blastema- a cause of oligomeganephronia? Pediatr Pathol 1994; 14:935-943
23. Drukker A. Oligonephropathy: from a rare childhood disorder to a possible health problem in the adult. Isr Med Assoc J 2002; 4:191 -195
24. Weber S, Moriniere V, Knuppel T, Charbit M, Dusek J, Ghiggeri GM, Jankauskiene A, Mir S, Montini G, Peco-Antic A, Wuhl E, Zurowska AM, Mehls O, Antigniac C, Schaefer F, Salomon R. Prevalence of mutations in renal developmental genes in children with renal hypodysplasia: results of the ESACAPE Study. J Am Soc Nephrol 2006; 17:2864-2870
25. Faa G, Gerosa C, Fanni D, Nemolato S, Locci A, Cabras T, Marinelli V, Puddu M, Zaffanello M, Monga G, Fanos V. Marked interindividual variability in renal maturation of preterm infants: lessons from autopsy. J Maternal-Fetal Neonatal Med 2010; 23 (S3):129-133
26. Hinchliffe SA, Howard CV, Lynch MR, Sargent PH, Judd BA, van Velzen D. Renal development arrest in sudden infant death syndrome. Pediatr Pathol 1993; 13:333-43
27. Sutherland MR, Gubhaju L, Moore L, Kent AL, Dahlstrom JE, Home RSC, Hoy WE, Bertram JF, Black MJ. Accelerated maturation and abnormal morphology in the preterm neonatal kidney. J Am Soc Nephrol 2011; 22:1365-1374
28. Rodriguez MM, Gomez AH, Abitbol CL, Chandar JJ, Duara S, Zilleruelo GE. Histomorphometric analysis of postnatal glomerulogenesis in extremely preterm infants. Pediatr Dev Pathol 2004; 7:17-25
29. Gubhaju L, Sutherland MR, Black MJ. Preterm birth and the kidney: implications for long-term health. Reprod Sci 2011; 18:322-333
30. Dinkel E, Bitscho J, Dittrich M, Schulte-Wissermann H, Ertel M. Renal growth in patients nephrectomized for Wilms tumor as compared to renal agenesis. Eur J Pediatr 1988; 147:54-58
31. Hill LM, Nowak A, Hartie R, Tush B. Fetal compensatory renal hypertrophy with a unilateral functioning kidney. Ultrasound Obstet Gynecol 2000; 15:191-193
32. Mandetl J, Peters CA, Estroff JA, Allred EN, Benacerraf BR. Human fetal compensatory renal growth. J Urol 1993; 15 (2Pt 2):790-792
33. Mansoor 0, Chandar J, Rodriguez MM, Abitbol CL, Seeheruvong W, Freundlich M, Zilleruello G. Long-term risk of chronic kidney disease in unilateral multicystic dysplastic kidney. Pediatr Nephrol 2011; 26:597-603
34. John U, Rudnik-Schoneborn S, Zerres K, Misselwitz J. Kidney growth and renal function in unilateral multicystic dysplastic kidney disease Pediatr Nephrol 1998; 12:567-571
35. Aslam M, Watson AR. Unilateral multyicystic dysplastic kidney: long- term outcomes. Arch Dis Child 2006; 91:820-823
36. Seeman T, Patzer L, John U, Dusek J, Vondrak K, Janda J, Misselwitz J. Blood pressure, renal function, and proteinuria in children with unilateral renal agenesis. Kidney Blood Pres Res 2006; 29:210-215
37. Abidari JM, Prk KH, Kennedy WA, Shortliffe LD. Serial followup of the contralateral renal size in in children with multicystic dysplastic kidney. J Urol 2002; 168:1821-1825
38. Funahashy Y, Hattori R, Yamamoto T, Kamihira 0, Moriya Y, Gotoh M. Change in contralateral renal parenchymal volume 1 week after unilateral nephrectomy. Urology 2009; 74:708-712
39. Jeon HG, Lee SR, Joo DJ, Oh YT, Kim MS, Kim YS, Yang SC, Han WK. Predictors of kidney volume change and delayed kidney function recovery after donor nephrectomy. J Urol 2010; 184:1057-1063
40. Ruggenenti P, Cravedi P, Remuzzi G. Microvascular and macrovascular diseases of the kidney. In: Taal MW, Chertow GM, Marsden PA, Skorecki K, Yu ASL, Brenner BM, eds. Brenner and Rector's The Kidney, 9th edition, Philadelphia: WB Saunders, 2011; 1297-1331
41. Nyengaard JR, Bendtsen TF. Glomerular number and size in relation to age, kidney weight and body surface in normal men. Anat Rec 1992; 232:194-201
42. Kaplan C, Pasternack B, Shah H, Gallo G. Age-related incidence of sclerotic glomeruli in human kidneys. Am J Pathol 1975; 80:227-234
43. Berg UB. Differences in decline in GFR with age between males and females. Reference data on clearances of inulin and pAH in potential kidney donors. Nephrol Dial Transpl 2006; 21:2577-2582
44. Borer JG, Kaefer M, Barnewolt CE, Elias ER, Hobbs N, Retik AB, Peters CA. Renal findings on radiological follow-up of patients with Beckwith- Wiedemann syndrome. J Urol. 1999; 161 (1):235-239
45. Mussa A, Peruzzi L, Chiesa N, De Crescenzo A, Russo S, Melis D, Tarani L, Baldassare G, Larizza L, Riccio A, Silengo M, Ferrero GB. Nephrological findings and genotype-phenotype correlation in Beckwith-Wiedemann syndrome. Pediatr Nephrol 2012; 27:397-406
46. Morison IM, Becroft DM, Taniguchi T, Woods CG, Reeve AE. Somatic overgrowth associated with overexpression of insulin-like growth factor II. Nat Med 1996; 2 (3):311-316
47. Alessandri JL, Cuillier F, Ramful D, Ernould S, Robin S, de Napoli- Cocci S, Riviere J-P, Rossignol S. Perlman syndrome: report, prenatal findings and review. Am J Med Genet A 2008; 146A:2352-2357
48. Choyke PL, Siegel MJ, Oz O, Sotelo-Avila C, DeBaun MR. Nonmalignant renal disease in pediatric patients with Beckwith-Wiedemann syndrome. Am J Roentgenol 1998; 171 (3):733-737
49. Goldman M, Smith A, Shuman C, Caluseriu O, Wei C, Steele L, Ray P, Sadowski P, Squire J, Weksberg R, Rosenblum ND. Renal abnormalities in Beckwith- Wiedemann syndrome are associated with 11p15. 5 uniparental disomy. J Am Soc Nephrol 2002; 13:2077-2084
50. Dempsey-Robertson M, Wilkes D, Stall A, Bush P. Incidence of abdominal tumors in syndromic and idiopathic hemihypertrophy/ isolated hemihyperptasia. J Pediatr Orthop 2012; 32:322-326
51. Cohen AH. Massive obesity and the kidney. A morphological and statistical study. Am J Pathol 1975; 8:117-130
52. Goumenos DS, Kawar B, El Nahas M, Conti S, Wagner B, Spyropoulos C, VtachojanisJG. Benigni A, Kalfarentsos F. Early histological changes in the kidney of people with morbid obesity. Nephrol Dial Transplant 2008; 24:3732-3738
53. Eknoyan G. Obesity and chronic kidney disease. Nefrologia 2011; 31:397-403
54. Seyer-Hansen K. Renal hypertrophy in experimental diabetes mellitus. Kidney Int 1983; 23:643-646
55. Tsutsui T, Kurita A, Kirihara N, Hon T, Kawakami E. Testicular compensatory hypertrophy related to hemicastration in prepubertal dogs. J Vet Med Sci 2004; 66:1021-1025
56. Hausman DBI, Lu J, Ryan DH, Flatt WP, Harris RBS. Compensatory growth of adipose tissue after partial lipectomy: involvement of serum factors. Exp Biol Med 2004; 229:512-520
57. Pagano MA, Tibaldi E, Gringeri E, Brunati AM. Tyrosine phosphorylation and liver regeneration: a glance at intracellular transducers. IUBMB Life 2012; 64:27-35
58. Konerding MA, Gibney BC, Lee GS, Lin M, Tsuda A, Meritzer SJ. Spatial dependence of alveolar angiogenesis in postpneumonectomy lung growth. Angiogenesis 2012; 15:23-32
59. Jackson SR, Lee J, Reddy R, Williams GN, Kikuchi A, Freiberg Y, Warburton D, Driscoll B. Partial pneumonectomy of telomerase null mice carrying shortened telomeres initiates cell growth arrest resulting in a limited compensatory growth response. Am J Physiol Lung Cell MolPhysiol 2011; 300:898-909
60. Hendry C, Rumballe B, Moritz K, Llittle MH. Defining and redefining the nephron progenitor population. Pediatr Nephrol 2011; 26:1395-406
61. Hauser P, Kainz A, Perco P, Bergmeister H, Mitterbauer C, Schwarz C, Regele HM, Mayer B, Meyer TW, Oberbauer R. Transcriptional response in the unaffected kidney after contralateral hydronephrosis or nephrectomy. Kidney Int 2005; 68:2497-2507
62. Benioal B, Lash LH. Influence of renal compensatory hypertrophy on mitochondrial energetic and redox status. Biochem Pahrmacol 2011; 81:295-303
63. Sugino N, Duffy G, Gulyassy PR Renal function after unilateral nephrectomy in normal man. Clin Res 1967; 15:1-43
64. Sinuani I, Beberashvili I, Averbukh Z, Cohn M, Gitelman I, Weissgarten J. Mesangial cells initiate compensatory tubular hypertrophy. Am J Nephrol 2010; 31:326-331
65. Brenner BM, Mackenzie HS. Nephron mass as a risk factor for progression of renal disease. Kidney Int Supl 1997; 63:S124-S127
66. Luyckx VA, Brenner BM. Low birth weight, nephron number, and kidney disease. Kidney IntSuppl 2005; 97:S68-S77
67. Nenov VD, Taal MW, Sakharova OV, Brenner BM. Multi-hit nature of chronic renal disease. Curr Opin Nephrol Hypertens 2000; 9:85-97.
68. Hoy WE, Bertram JF, Douglas Denton R, Zimany M, Samuel T, Hughson MD. Nephron number, glomerular volume, renal disease and hypertension. Curr Opin Nephrol Hypertens 2008; 17:258-265
69. Hoy WE, Douglas-Denton RN, Hughson MD, Cass A, Johnson K, Bertram JF. Kidney Int Suppl 2003 Feb; 83:S31-7
70. Douglas-Denton RN, McNamara BJ, Hoy WE, Hughson MD, Bertram JF. Does nephron number matter in the development of kidney disease? Ethn Dis 2006; 16 (S2):40-45
71. Okuda S, Motomura K, Sanai T, Onoyama K, Fujishima M. High incidence of glomerular sclerosis in rats subjected to uninephrectomy at young age. Nephron 1988; 49:240-244
72. Moritz KM, Wintour EM, Dodic M. Fetal uninephrectomy leads to postnatal hypertension and compromised renal function. Hypertension 2002; 39:1071-1076
73. Gruenwald S, Tack I, Chauveau D, Bennet A, Caron P. Impact of growth hormone hypersecretion on the adult human kidney. Ann Endocrinol 2011; 72:485-495
74. Flyvbjerg A, Bennett WF, Rasch R, van Neck JW, Groffen CA, Kopchick JJ, Scarlett JA. Compensatory renal growth in uninephrectomized adult mice is growth hormone dependent. Kidney Int 1999; 56:2048-2054
75. Ristic-Cingel V, Flyvbjerg A, Crop SLS. The physiological and pathophysiological roles of the GH/IGF-axis in the kidney: Lessons from experimental rodent models. Growth Horm IGF Res 2004; 14:418-430
76. Haramati A, Lumpkin MD, Mulroney SE. Early increase in pulsatile growth hormone release after unilateral nephrectomy in adult mice. Am J Physiol Renal Fluid Electrolyte Physiol 1994; 266:628-632
77. Mulroney SE, Woda C, Johnson M, Pesce C. Gender differences in renal growth and function after uninephrectomy in adult rats. Kidney Int 1999; 56:944-953
78. Shohat J, Davidowitz M, Erman A, Silbergeld A, Boner G. Serum and renal IGF-1 levels after uninephrectomy in the rat. Scand J Clin Lab Invest 1997; 57:167-173
79. Fervenza FC, Tsao T, Hsu F, Rabkin R. Intrarenal insulin-like growth factor-1 axis after unilateral nephrectomy in rat. J Am Soc Nephrol 1999; 10:43-50
80. Gronboek H, Nielsen B, Flyvbjerg A, Orskov H. Effect of graded renal ablation on kidney and serum insulin-like growth factor-l (IGF-1) and IGF binding proteins in rats: relation to compensatory renal growth. Metabolism 1997; 46:29-35
81. El Nahas AM, Le Carpentier JE, Bassett AH. Compensatory renal growth: role of growth hormone and insulin-like growth factor-l. Nephrol Dial Transplant 1990; 5:123-129
82. Haylor J, Hickling H, El Eter E, Moir A, Oldroyd S, Hardisty C, El Nahas M. JB3, an IGF-I receptor antagonist inhibits early renal growth in diabetic and uninephrectomized rats. J Am SocNephrol 2000; 11:2027-2035
83. Landau D, Biada J, Chen Y, Sood S, Yakar S, LeRoith D, Segev Y, Rabkin R. A marked deficiency in circulating and renal IGF-I peptide does not inhibit compensatory renal enlargement in uninephrectomized mice. Growth Horm IGF Res 2011; 21:279-284
84. Flyvbjerg A, Schrijvers BF, De Vriese AS, Tilton RG, Rasch R. Compensatory glomerular growth after unilateral nephrectomy is VEGF dependent. Am J PhysiolEndocrinol Metab 2002; 283:E362-E366
85. Schrijvers BF, Flyvbjerg A, Tilton RG, Rasch R, Lameire NH, De Vriese AS. Pathophysiological role of vascular endothelial growth factor in the remnant kidney. Nephron ExpNephrol 2005; 101:e9-e15
86. Hamm LL, Hering-Smith KS, Vehaskari VM. Epidermal growth factor and the kidney. SeminNephrol 1993; 13:109-115
87. Okada T, Omoto-Kitao M, Mukamooto M, Nakamura J, Mino M. Kondo T, Takeshita A, Kusakabe KT, Kato K. Compensatory renal growth in epidermal growth factor. J Vet Med Sci 2010; 72:975-980
88. Nagaike M, Hirao S, Tajima H, Noji S, Taniguchi S, Matsumoto K, Nakamura T. Renotropic functions of hepatocyte growth factor in renal regeneration after unilateral nephrectomy. J Biol Chem 1991; 266:22781-22784
89. Tsau Y-K, Tsal l-J, Chen Y-M. Transient reciprocal change of renal hepatocyte growth factor and transforming growth factor - b1 may relate to renal hypertrophy in rats with liver injury or unilateral nephrectomy. Pediatr Res 2006; 59:494-499
90. Fine LG, Norman J. Cellular events in renal hypertrophy. Ann Rev Physiol 1989; 51:19-32
91. Liu B, Preisig PA. Compensatory renal hypertrophy is mediated by a cell cycle -dependent mechanism. Kidney Int 2002; 62:1650-1658
92. Chen JK, Chen J, Neilson EG, Harris RC. Role of mammalian target of rapamycin signaling in compensatory renal hypertrophy. J Am Soc Nephrol 2005; 16:1384-1391
93. Fingar DC, Salama S, Tsou C, Harlow E, Blenis J. Mammalian cell size is controlled by mTOR and its down-stream targets S6K1 and 4EBP1 / elF4E. Gene Dev 2002; 16:1472-1487
94. Chen J-K, Chen J, Thomas G, Kozma SC, Harris RC. S6 kinase 1 knockout inhibits uninephrectomy- or diabetes-induced renal hypertrophy. Am J Physiol Renal Physiol 2009; 297:F585-F893
95. Sinuani I, Weissgarten J, Beberashvili I, Rapoport MJ, Sandbank J, Feldman L, Albeck M, Averbukh Z, Sredni B. The cyclin kinase inhibitor p57kip2 regulates TGFb-induced compensatory tubular hypertrophy: effect of the immunomodulator AS101. Nephrol Dial Transplant 2009; 24:2328-2338
96. Nagasu H, Satoh M, Kuwabara A, Yorimitsu D, Kidokoro K, Nishi Y, Tomita N, Sasaki T, Kashihara N. Overexpression of klotho protein modulates uninephrectomy-induced compensatory renal hypertrophy by suppressing IGF-I signals. Biochem Biophys Res Commun 2011; 407:39-43
97. Kambham N, Markowitz GS, Valeri AM, Lin J, D'Agati VD. Obesity- related glomerulopathy: an emerging epidemic. Kidney Int 2001; 59:1498-1509
98. Saito A, Takeda T, Hama H, Oyama Y, Hosaka K, Tanuma A, Kaseda R, Ueno M, Nishi S, Ogasawara S, Gondira F, Suzuki Y, Gejyo F. Role of megalin, a proximal tubular endocytic receptor, in the pathogenesis of diabetic and metabolic syndrome-related nephropathy: protein metabolic overload hypothesis. Nephrology 2005; 10:S26-S31
99. Amakasu K, Suzuki K, Katayama K, Suzuki H. Age-related pathophysiological changes in rats with unilateral renal agenesis. J Vet Med Sci 2011; 73:787-795
100. Benz K, Campean V, Cordasic N, Karpe B, Neuhuber W, Mall G, Hartner A, Hilgers KF, Amann K. Early glomerular alterations in genetically determined low nephron number. Am J Physiol Renal Physiol 2011; 300:F521-F530
101. Wang Y, Heilig KO, Minto AW, Chen S, Xiang M, Dean DA, Geiger RC, Chang A, D Pravtcheva DD, Schlimme M, Deb DK, Wang Y, Heilig CW. Nephron-deficient Fvb mice develop rapidly progressive renal failure and heavy albuminuria involving excess glomerular GLUT1 and VEGF. Lab Invest 2010; 90:83-97
102. Fan Y, Bergman A. Apoptosis-induced compensatory proliferation. The cell is dead. Long live the Cell!! Trends Cell Biol 2008; 18:467-473
103. Gerhold AR, Richter DJ, Yu AS, Harihn IK. Identification and characterization of genes required for compensatory growth in Drosophila. Genetics 2011; 189:1309-1326
104. Rosenbaum DM, Korngold E, Teele RL. Sonographic assessment of renal length in normal children. Am J Roentgenol 1984; 142:467-469.
105. Konus- Konus OL, Ozdemir A, Akkaya A, Erbas G, Celik H, Isik S. Normal liver, spleen and kidney dimensions in neonates, infants and children: evaluation with sonography. Am J Roentgenol 1998; 171:1693-1698.
106. Dinket E, Ertel L, Dittrich M, Peters H, Berres M, Schulte-Wissermann H. Kidney size in childhood : sonographic growth charts for kidney length and volume. Pediatr Radiol 1985; 15:38-43
107. Spira EM, Jacobi C, Frankenschmidt A, PohlM, von Schnaken burg C. Sonographic long-term study: paediatric growth charts for single kidneys. Arch Dis Child 2009; 94:693-698
108. Cho JY, Moon MH, Lee YH, Kim KW, Kim SH. Measurement of compensatory hyperplasia of the contralateral kidney: usefulness for differential diagnosis of fetal unilateral empty renal fossa. Ultrasound Obstet Gynecol 2009; 34:515-520
109. Baudoin P, Provoost AP, Molenaar JC. Renal function up to 50 years after unilateral nephrectomy in childhood. Am J Kidney Dis1993; 21:603-611
110. Argueso LR, Ritchey ML, Boyle ET Jr, Milliner DS, Bergstrahl EJ, Kramer SA. Prognosis of patients with unilateral agenesis Pediatr Nephrol 1992; 6:412-416
111. Wikstad I, Celsi G, Larsson L, Herin P, Aperia A. Kidney function in adults born with unilateral renal agenesis or nephrectomized in childhood. Pediatr Nephrol 1988; 2:177-182
112. Schmitz A, Christensen CK, Christensen T, Soiling K. No microalbuminuria or other adverse effects of long-standing hyperfiltration in humans with one kidney. Am J Kidney Dis 1989:13:131-136
113. Sanna-Cherchi S, Ravani P, Corbani V, Parodi S, Riccardo Haupt, Piaggio G. Renal outcome in patients with congenital anomalies of the kidney and urinary tract. Kidney Int 2009; 76:528-533
114. Schreuder MF, Langemeijer ME, Bokenkamp A, Delemarre-Van de Waal HA, Van Wijk JA. Hypertension and microalbuminuria in children with congenital solitary kidneys. J Paediatr Child Health 2008; 44:363-368
115. Robitaille P, Mongeau JG, Lortie L, Sinnassamy P. Long-term follow- up of patients who underwent unilateral nephrectomy in childhood. Lancet 1985; 1:1297-1299
116. Ibrahim HN, Foley R, Tan L, Rogers T, Bailey RF, Guo H, Gross CR, Matas AJ. Long-term consequences of kidney donation. N Engl J Med 2009; 360:459-469
117. Najarian JS, Chavers BM, McHugh LE, Matas AJ. 20 years or more follow-up of living kidney donors. Lancet 1992:340:807-810
118. Wasilewska A, Zoch-Zwierz W, Taranta-Janusz K. Urinary transforming growth factor beta 1in children and adolescents with congenital solitary kidney. Pediatr Nephrol 2009; 24:753-759
119. Wolf G, Mueller E, Staht RA, Ziyadeh FN. Angiotensin ll-induced hypertrophy of cultured murine proximal tubular cells is mediated by endogenous transforming growth factor-beta. J Clin Invest 1993; 92:1366-1372
120. Yamamoto T, Noble NA, Miller DE, Border WA. Sustained expression of TGF-beta1 underlies development of progressive kidney fibrosis Kidney Int 1994; 45:916-927
121. Gonzalez E, Gutierrez E, Morales E, Hernandez E, Andres A, Bello I, Diaz-Gonzalez R, Leiva O, Praga M. Factors influencing the progression of renal damage in patients with unilateral renal agenesis and remnant kidney. Kidney Int 2005; 68 (1):263-270
122. Grinsell MM, Showalter S, Gordon KA, Norwood VF. Single kidney and sports participation: perception versus reality. Pediatrics 2006; 118 (3):1019-1027
123. Han DC, Hoffman BB, Hong SW, Guo J, Ziyadeh FN. Therapy with antisense TGF-1 oligodeoxynucleotides reduces kidney weight and matrix mRNAs in diabetic mice. Am J Physiol 2000; 278:F628-F34