Overexpression of klotho protein modulates uninephrectomy-induced compensatory renal hypertrophy by suppressing IGF-I signals

Biochemical and Biophysical Research Communications

Volumn 407, Issue 1, 2011, Pages 39-43

  Nagasu, Hajime ^a   Satoh, Minoru ^a   Kuwabara, Atsunori ^a   Yorimitsu, Daisuke ^a   Kidokoro, Kengo ^a   Nishi, Yuko ^a   Tomita, Naruya ^a   Sasaki, Tamaki ^a   Kashihara, Naoki ^a  

^a KAWASAKI MEDICAL SCHOOL   (Japan)

Author keywords

Compensatory hypertrophy; Insulin like growth factor; Insulin receptor substrate; Mammalian target of rapamycin; NAD(P)H oxidase; Proximal tubular cell; Reactive oxygen species

Indexed keywords

KLOTHO PROTEIN; SOMATOMEDIN C;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; GENE EXPRESSION; GENE OVEREXPRESSION; GENE REPRESSION; GENETIC TRANSFECTION; HISTOPATHOLOGY; HUMAN; HUMAN CELL; IN VITRO STUDY; KIDNEY HYPERTROPHY; KIDNEY PROXIMAL TUBULE; KIDNEY PROXIMAL TUBULE CELL; MALE; MOUSE; NONHUMAN; PLASMID; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TRANSGENIC ANIMAL; UNINEPHRECTOMY; WILD TYPE;

ANIMALS; CELL LINE; GLUCURONIDASE; HUMANS; HYPERTROPHY; INSULIN-LIKE GROWTH FACTOR I; KIDNEY; KIDNEY GLOMERULUS; KIDNEY TUBULES, PROXIMAL; MICE; MICE, TRANSGENIC; NADPH OXIDASE; NEPHRECTOMY; SIGNAL TRANSDUCTION; TOR SERINE-THREONINE KINASES;

MAMMALIA; MUS; MUS MUSCULUS;

EID: 79953163783     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2011.02.089     Document Type: Article

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