Defining and redefining the nephron progenitor population

Pediatric Nephrology

Volumn 26, Issue 9, 2011, Pages 1395-1406

  Hendry, Caroline ^a   Rumballe, Bree ^a   Moritz, Karen ^a   Little, Melissa H ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

Cap mesenchyme; Kidney development; Mesenchyme to epithelial transition; Nephron progenitor; Self renewal; Specification

Indexed keywords

WNT PROTEIN;

CELL POPULATION; CONFERENCE PAPER; KIDNEY DEVELOPMENT; MESENCHYME; NEPHRON; NONHUMAN; PRIORITY JOURNAL; STEM CELL; URETER;

ANIMALS; CELL DIFFERENTIATION; CELL LINEAGE; CELL PROLIFERATION; EPITHELIAL-MESENCHYMAL TRANSITION; HUMANS; MESENCHYMAL STEM CELLS; NEPHRONS; ORGANOGENESIS; STEM CELL NICHE;

EID: 80052297865     PISSN: 0931041X     EISSN: 1432198X     Source Type: Journal    
DOI: 10.1007/s00467-010-1750-4     Document Type: Conference Paper

References (90)

1. L Saxen H Sariola 1987 Early organogenesis of the kidney Pediatr Nephrol 1 385 392 3153305 10.1007/BF00849241 1:STN:280:DyaK3M%2Fislajsw%3D%3D (Pubitemid 18016633)
2. JW Mugford J Yu A Kobayashi AP McMahon 2009 High-resolution gene expression analysis of the developing mouse kidney defines novel cellular compartments within the nephron progenitor population Dev Biol 333 2 312 323 19591821 10.1016/j.ydbio.2009.06.043 1:CAS:528:DC%2BD1MXhtVKlsL7J
3. KM Georgas BA Rumballe MT Valerius HS Chiu RD Thiagarajan E Lesieur BJ Aronow EW Brunskill AN Combes D Tang D Taylor SM Grimmond SS Potter AP McMahon MH Little 2009 Analysis of early nephron patterning reveals a role for distal RV proliferation in fusion to the ureteric tip via a cap mesenchyme-derived connecting segment Dev Biol 332 2 273 286 19501082 10.1016/j.ydbio.2009.05.578 1:CAS:528:DC%2BD1MXptVehu7k%3D
4. JA Davies JB Bard 1998 The development of the kidney Curr Top Dev Biol 39 245 301 9476003 10.1016/S0070-2153(08)60458-5 1:STN:280:DyaK1c7js1Crsg%3D%3D
5. MH Little 2006 Regrow or repair - potential regenerative therapies for the kidney J Am Soc Nephrol 17 9 2390 2401 16870708 10.1681/ASN.2006030218 (Pubitemid 44300955)
6. A Kobayashi MT Valerius JW Mugford TJ Carroll M Self G Oliver AP McMahon 2008 Six2 defines and regulates a multipotent self-renewing nephron progenitor population throughout mammalian kidney development Cell Stem Cell 3 2 169 181 18682239 10.1016/j.stem.2008.05.020 1:CAS:528:DC%2BD1cXhtVegtr%2FM
7. HA Hartman HL Lai LT Patterson 2007 Cessation of renal morphogenesis in mice Dev Biol 310 379 387 17826763 10.1016/j.ydbio.2007.08.021 1:CAS:528:DC%2BD2sXhtFSksrvJ (Pubitemid 47496040)
8. M Hughson AB Farris 3rd R Douglas-Denton WE Hoy JF Bertram 2003 Glomerular number and size in autopsy kidneys: the relationship to birth weight Kidney Int 63 2113 2122 12753298 10.1046/j.1523-1755.2003.00018.x (Pubitemid 36605822)
9. M Self OV Lagutin B Bowling J Hendrix Y Cai GR Dressler G Oliver 2006 Six2 is required for suppression of nephrogenesis and progenitor renewal in the developing kidney EMBO J 25 5214 5228 17036046 10.1038/sj.emboj.7601381 1:CAS:528:DC%2BD28XhtFChsrzL (Pubitemid 44658538)
10. S Boyle A Misfeldt KJ Chandler KK Deal EM Southard-Smith DP Mortlock HS Baldwin M de Caestecker 2008 Fate mapping using Cited1-CreERT2 mice demonstrates that the cap mesenchyme contains self-renewing progenitor cells and gives rise exclusively to nephronic epithelia Dev Biol 313 234 245 18061157 10.1016/j.ydbio.2007.10.014 1:CAS:528:DC%2BD1cXhsVKquw%3D%3D (Pubitemid 350298313)
11. GR Dressler 2006 The cellular basis of kidney development Ann Rev Cell Dev Biol 22 509 529 10.1146/annurev.cellbio.22.010305.104340 1:CAS:528:DC%2BD28Xht1yjs7jL
12. KM Schmidt-Ott J Barasch 2008 WNT/beta-catenin signaling in nephron progenitors and their epithelial progeny Kidney Int 74 1004 1008 18633347 10.1038/ki.2008.322 1:CAS:528:DC%2BD1cXhtFyqtbfP
13. AT Dudley RE Godin EJ Robertson 1999 Interaction between FGF and BMP signaling pathways regulates development of metanephric mesenchyme Genes Dev 13 1601 1613 10385628 10.1101/gad.13.12.1601 1:CAS:528:DyaK1MXktlOhsbs%3D (Pubitemid 29297927)
14. K Osafune M Takasato A Kispert M Asashima R Nishinakamura 2006 Identification of multipotent progenitors in the embryonic mouse kidney by a novel colony-forming assay Development 133 151 161 16319116 10.1242/dev.02174 1:CAS:528:DC%2BD28XhtFGgurs%3D (Pubitemid 43169329)
15. AO Perantoni O Timofeeva F Naillat C Richman S Pajni-Underwood C Wilson S Vainio LF Dove M Lewandoski 2005 Inactivation of FGF8 in early mesoderm reveals an essential role in kidney development Development 132 3859 3871 16049111 10.1242/dev.01945 1:CAS:528:DC%2BD2MXhtFSrtrnI (Pubitemid 41410251)
16. J Barasch J Yang CB Ware T Taga K Yoshida H Erdjument-Bromage P Tempst E Parravicini S Malach T Aranoff JA Oliver 1999 Mesenchymal to epithelial conversion in rat metanephros is induced by LIF Cell 99 377 386 10571180 10.1016/S0092-8674(00)81524-X 1:CAS:528:DyaK1MXns1egsLo%3D
17. SY Plisov K Yoshino LF Dove KG Higinbotham JS Rubin AO Perantoni 2001 TGF beta2, LIF and FGF2 cooperate to induce nephrogenesis Development 128 1045 1057 11245570 1:CAS:528:DC%2BD3MXjtFOlt74%3D (Pubitemid 32401420)
18. A Marlier T Gilbert 2004 Expression of retinoic acid-synthesizing and -metabolizing enzymes during nephrogenesis in the rat Gene Expr Patterns 5 179 185 15567713 10.1016/j.modgep.2004.08.005 1:CAS:528:DC%2BD2cXhtVahur%2FL (Pubitemid 39618926)
19. K Osafune R Nishinakamura S Komazaki M Asashima 2002 In vitro induction of the pronephric duct in Xenopus explants Dev Growth Differ 44 161 167 11940102 10.1046/j.1440-169x.2002.00631.x (Pubitemid 34437837)
20. D Kim GR Dressler 2005 Nephrogenic factors promote differentiation of mouse embryonic stem cells into renal epithelia J Am Soc Nephrol 16 3527 3534 16267156 10.1681/ASN.2005050544 1:CAS:528:DC%2BD28XhvFWqsA%3D%3D (Pubitemid 46211273)
21. U Grieshammer C Cebrian R Ilagan E Meyers D Herzlinger GR Martin 2005 FGF8 is required for cell survival at distinct stages of nephrogenesis and for regulation of gene expression in nascent nephrons Development 132 3847 3857 16049112 10.1242/dev.01944 1:CAS:528:DC%2BD2MXhtFSrtrnP (Pubitemid 41410250)
22. SD Gerber F Steinberg M Beyeler PM Villiger B Trueb 2009 The murine Fgfrl1 receptor is essential for the development of the metanephric kidney Dev Biology 335 106 119 10.1016/j.ydbio.2009.08.019 1:CAS:528:DC%2BD1MXht1Onsr%2FI
23. K Stark S Vainio G Vassileva AP McMahon 1994 Epithelial transformation of metanephric mesenchyme in the developing kidney regulated by Wnt-4 Nature 372 679 683 7990960 10.1038/372679a0 1:CAS:528:DyaK2MXislantL0%3D
24. A Kispert S Vainio AP McMahon 1998 Wnt-4 is a mesenchymal signal for epithelial transformation of metanephric mesenchyme in the developing kidney Development 125 4225 4234 9753677 1:CAS:528:DyaK1cXotVaqsrc%3D (Pubitemid 28528930)
25. TJ Carroll JS Park S Hayashi A Majumdar AP McMahon 2005 Wnt9b plays a central role in the regulation of mesenchymal to epithelial transitions underlying organogenesis of the mammalian urogenital system Dev Cell 9 283 292 16054034 10.1016/j.devcel.2005.05.016 1:CAS:528:DC%2BD2MXovFSgs70%3D (Pubitemid 41051746)
26. A Kispert S Vainio L Shen DH Rowitch AP McMahon 1996 Proteoglycans are required for maintenance of Wnt-11 expression in the ureter tips Development 122 3627 3637 8951078 1:CAS:528:DyaK28XntlSkur0%3D (Pubitemid 26396004)
27. A Majumdar S Vainio A Kispert J McMahon AP McMahon 2003 Wnt11 and Ret/Gdnf pathways cooperate in regulating ureteric branching during metanephric kidney development Development 130 3175 3185 12783789 10.1242/dev.00520 1:CAS:528:DC%2BD3sXlvF2gtL0%3D (Pubitemid 36926955)
28. T Graf M Busslinger 2008 B young again Immunity 28 606 608 18482566 10.1016/j.immuni.2008.04.004 1:CAS:528:DC%2BD1cXmtlagtrk%3D (Pubitemid 351636246)
29. JW Mugford P Sipila JA McMahon AP McMahon 2008 Osr1 expression demarcates a multi-potent population of intermediate mesoderm that undergoes progressive restriction to an Osr1-dependent nephron progenitor compartment within the mammalian kidney Dev Biol 324 88 98 18835385 10.1016/j.ydbio.2008.09.010 1:CAS:528:DC%2BD1cXhsVSjs7fL
30. GR Dressler U Deutsch K Chowdhury HO Nornes P Gruss 1990 Pax2, a new murine paired-box-containing gene and its expression in the developing excretory system Development 109 787 795 1977574 1:CAS:528:DyaK3MXhsFyjtr0%3D
31. GR Dressler 2009 Advances in early kidney specification, development and patterning Development 136 3863 3874 19906853 10.1242/dev.034876 1:CAS:528:DC%2BC3cXislSmuw%3D%3D
32. M Torres E Gomez-Pardo GR Dressler P Gruss 1995 Pax-2 controls multiple steps of urogenital development Development 121 4057 4065 8575306 1:CAS:528:DyaK28XhvFSkuw%3D%3D (Pubitemid 26007357)
33. PD Brophy L Ostrom KM Lang GR Dressler 2001 Regulation of ureteric bud outgrowth by Pax2-dependent activation of the glial derived neurotrophic factor gene Development 128 4747 4756 11731455 1:CAS:528:DC%2BD3MXptlKqsrc%3D (Pubitemid 33138585)
34. DE Phelps GR Dressler 1993 Aberrant expression of Pax-2 in Danforth's short tail (Sd) mice Dev Biol 157 251 258 8482415 10.1006/dbio.1993.1129 1:STN:280:DyaK3s3ks1SltQ%3D%3D (Pubitemid 23164973)
35. SR Patel D Kim I Levitan GR Dressler 2007 The BRCT-domain containing protein PTIP links PAX2 to a histone H3, lysine 4 methyltransferase complex Dev Cell 13 580 592 17925232 10.1016/j.devcel.2007.09.004 1:CAS:528: DC%2BD2sXht1SjsrjE (Pubitemid 47500812)
36. G Sajithlal D Zou D Silvius PX Xu 2005 Eya1 acts as a critical regulator for specifying the metanephric mesenchyme Dev Biol 284 323 336 16018995 10.1016/j.ydbio.2005.05.029 1:CAS:528:DC%2BD2MXpt1elu7c%3D (Pubitemid 41188139)
37. KQ Gong AR Yallowitz H Sun GR Dressler DM Wellik 2007 A Hox-Eya-Pax complex regulates early kidney developmental gene expression Mol Cell Biol 27 21 7661 7668 17785448 10.1128/MCB.00465-07 1:CAS:528:DC%2BD2sXht1Glt77M (Pubitemid 350033671)
38. RG James TM Schultheiss 2005 Bmp signaling promotes intermediate mesoderm gene expression in a dose-dependent, cell-autonomous and translation-dependent manner Dev Biol 288 113 125 16243309 10.1016/j.ydbio.2005.09.025 1:CAS:528:DC%2BD2MXht1OltLfF (Pubitemid 41713158)
39. RG James CN Kamei QR Wang R Jiang TM Schultheiss 2006 Odd-skipped related 1 is required for development of the metanephric kidney and regulates formation and differentiation of kidney precursor cells Development 133 2995 3004 16790474 10.1242/dev.02442 1:CAS:528:DC%2BD28XovFKrtbw%3D (Pubitemid 44314276)
40. H Ohto T Takizawa T Saito M Kobayashi K Ikeda K Kawakami 1998 Tissue and developmental distribution of Six family gene products Int J Dev Biol 42 141 148 9551859 1:STN:280:DyaK1c3htFGrtg%3D%3D (Pubitemid 28109375)
41. CA Boucher CL Winchester GM Hamilton AD Winter KJ Johnson ME Bailey 2000 Structure, mapping and expression of the human gene encoding the homeodomain protein, SIX2 Gene 247 145 151 10773454 10.1016/S0378-1119(00)00105-0 1:CAS:528:DC%2BD3cXisV2ksLw%3D (Pubitemid 30201566)
42. PX Xu W Zheng L Huang P Maire C Laclef D Silvius 2003 Six1 is required for the early organogenesis of mammalian kidney Development 130 3085 3094 12783782 10.1242/dev.00536 1:CAS:528:DC%2BD3sXlvF2gt7g%3D (Pubitemid 36926948)
43. H Kobayashi K Kawakami M Asashima R Nishinakamura 2007 Six1 and Six4 are essential for Gdnf expression in metanephric mesenchyme and ureteric bud formation, while Six1 deficiency alone causes mesonephric-tubule defects Mech Dev 124 290 303 17300925 10.1016/j.mod.2007.01.002 1:CAS:528: DC%2BD2sXjtVahu7Y%3D (Pubitemid 46400394)
44. R Nishinakamura Y Matsumoto K Nakao K Nakamura A Sato NG Copeland DJ Gilbert NA Jenkins S Scully DL Lacey M Katsuki M Asashima T Yokota 2001 Murine homolog of SALL1 is essential for ureteric bud invasion in kidney development Development 128 3105 3115 11688560 1:CAS:528:DC%2BD3MXmslSrsrg%3D (Pubitemid 32825755)
45. L Chai J Yang C Di W Cui K Kawakami R Lai Y Ma 2006 Transcriptional activation of the Sall1 by the human Six1 homeodomain during kidney development J Biol Chem 281 18918 18926 16670092 10.1074/jbc.M600180200 1:CAS:528: DC%2BD28Xms1GrtL4%3D (Pubitemid 44035394)
46. Q Jiang S Fujimura C Kobayashi R Nishinakamura 2010 Overexpression of Sall1 in vivo leads to reduced body weight without affecting kidney development J Biochem 147 445 450 20053786 10.1093/jb/mvp214 1:CAS:528:DC%2BC3cXitlaqu7g%3D
47. DM Wellik PJ Hawkes MR Capecchi 2002 Hox11 paralogous genes are essential for metanephric kidney induction Genes Dev 16 1423 1432 12050119 10.1101/gad.993302 1:CAS:528:DC%2BD38XkslWhtb4%3D (Pubitemid 34615094)
48. JW Mugford P Sipila A Kobayashi RR Behringer AP McMahon 2008 Hoxd11 specifies a program of metanephric kidney development within the intermediate mesoderm of the mouse embryo Dev Biol 319 396 405 18485340 10.1016/j.ydbio.2008. 03.044 1:CAS:528:DC%2BD1cXovVGiurw%3D
49. B Fogelgren S Yang IC Sharp OJ Huckstep W Ma SJ Somponpun EC Carlson CF Uyehara S Lozanoff 2009 Deficiency in Six2 during prenatal development is associated with reduced nephron number, chronic renal failure and hypertension in Br/+ adult mice Am J Physiol Renal Physiol 296 F1166 F1178 19193724 10.1152/ajprenal.90550.2008 1:CAS:528:DC%2BD1MXlvFanu7s%3D
50. AR Yallowitz KQ Gong IT Swinehart LT Nelson DM Wellik 2009 Non-homeodomain regions of Hox proteins mediate activation versus repression of Six2 via a single enhancer site in vivo Dev Biol 335 156 165 19716816 10.1016/j.ydbio.2009.08.020 1:CAS:528:DC%2BD1MXht1Onsr%2FF
51. S Boyle T Shioda AO Perantoni M de Caestecker 2007 Cited1 and Cited2 are differentially expressed in the developing kidney but are not required for nephrogenesis Dev Dyn 236 2321 2330 17615577 10.1002/dvdy.21242 1:CAS:528:DC%2BD2sXhtV2hs7vE (Pubitemid 47293774)
52. M Couillard M Trudel 2009 C-myc as a modulator of renal stem/progenitor cell population Dev Dyn 238 405 414 19161241 10.1002/dvdy.21841 1:CAS:528:DC%2BD1MXjtlyhsL4%3D
53. G Mugrauer P Ekblom 1991 Contrasting expression patterns of three members of the myc family of protooncogenes in the developing and adult mouse kidney J Cell Biol 112 13 25 1986001 10.1083/jcb.112.1.13 1:CAS:528:DyaK3MXktVSlsw%3D%3D (Pubitemid 21909596)
54. JA Kreidberg H Sariola JM Loring M Maeda J Pelletier D Housman R Jaenisch 1993 WT-1 is required for early kidney development Cell 74 679 691 8395349 10.1016/0092-8674(93)90515-R 1:CAS:528:DyaK3sXlsFKrurg%3D (Pubitemid 23259748)
55. S Sims-Lucas R Young G Martinez D Taylor SM Grimmond R Teasdale MH Little J Bertram G Caruana 2010 Redirection of renal mesenchyme to stromal and chondrocytic fates in the presence of TGF-β2 Differentiation 79 272 284 20163909 10.1016/j.diff.2010.01.004 1:CAS:528:DC%2BC3cXnt1GhsL0%3D
56. M Lusis J Li J Ineson J Li MH Little 2010 Isolation and culture of metanephric mesenchyme-derived nephrospheres reinforces evidence that embryonic renal progenitors are multipotent and exhaust during cessation of nephron formation Stem Cell Research 5 23 39 20434421 10.1016/j.scr.2010.03.003 1:CAS:528:DC%2BC3cXpsFentbc%3D
57. Z Zhuang MJ Merino AO Vortmeyer B Bryant AE Lash C Wang MT Deavers WF Shelton S Kapur RS Chandra 1997 Identical genetic changes in different histologic components of Wilms' tumors J Natl Cancer Inst 89 1148 1152 9262253 10.1093/jnci/89.15.1148 1:STN:280:DyaK2svgsVWltQ%3D%3D (Pubitemid 27337929)
58. E Fuchs 2009 Finding one's niche in the skin Cell Stem Cel 4 499 502 10.1016/j.stem.2009.05.001 1:CAS:528:DC%2BD1MXnt1GgtL8%3D
59. MR Walker KK Patel TS Stappenbeck 2009 The stem cell niche J Pathol 217 2 169 180 19089901 10.1002/path.2474 1:STN:280:DC%2BD1M%2Fgs1Ohsg%3D%3D
60. P Eliasson JI Jönsson 2010 The hematopoietic stem cell niche: low in oxygen but a nice place to be J Cell Physiol 222 17 22 19725055 10.1002/jcp.21908 1:CAS:528:DC%2BD1MXhtlGgtrrP
61. D Mathur A Bost I Driver B Ohlstein 2010 A transient niche regulates the specification of Drosophila intestinal stem cells Science 8327 5962 210 213 10.1126/science.1181958
62. BD Humphreys MT Valerius A Kobayashi JW Mugford S Soeung JS Duffield AP McMahon JV Bonventre 2008 Intrinsic epithelial cells repair the kidney after injury Cell Stem Cell 2 284 291 18371453 10.1016/j.stem.2008.01.014 1:CAS:528:DC%2BD1cXjslegtrk%3D (Pubitemid 351298594)
63. WE Hoy JF Bertram RD Denton M Zimanyi T Samuel MD Hughson 2008 Nephron number, glomerular volume, renal disease and hypertension Curr Opin Nephrol Hypertens 17 258 265 18408476 10.1097/MNH.0b013e3282f9b1a5 (Pubitemid 351535928)
64. Moritz KM, Cullen-McEwen LA (2006) Kidney Development and Fetal Programming. In: Early Life Origins of Health and Adult Disease. Eds Wintour-Coghlan EM, Owens JA. Landes Bioscience, pp.130-144 (Pubitemid 47413316)
65. BM Brenner DL Garcia S Anderson 1988 Glomeruli and blood pressure. Less of one, more the other? Am J Hypertens 1 335 347 3063284 1:STN:280: DyaL1M7gsFegtA%3D%3D
66. Moritz KM, Wintour EM, Dodic M (2006) Renal development and programming. In: Gluckman PD, Hanson MA (eds) Developmental Origins of Health and Disease - A Biomedical Perspective, 23rd edn. University Press, Cambridge, pp 310-322
67. BM Brenner S Anderson 1992 The interrelationships among filtration surface area, blood pressure, and chronic renal disease J Cardiovasc Pharmacol 19 Suppl 6 S1 S7 1382155
68. CC Hoppe RG Evans JF Bertram KM Moritz 2007 The effects of dietary protein restriction on nephron number in the mouse Am J Physiol Regul Integr Comp Physiol 292 R1768 R1774 17272668 10.1152/ajpregu.00442.2006 1:CAS:528:DC%2BD2sXlslShsb8%3D (Pubitemid 46708530)
69. ME Wlodek A Mibus A Tan AL Siebel JA Owens KM Moritz 2007 Normal lactational environment restores nephron endowment and prevents hypertension after placental restriction in the rat J Am Soc Nephrol 18 1688 1696 17442788 10.1681/ASN.2007010015 1:CAS:528:DC%2BD2sXnt1Squrg%3D (Pubitemid 46870306)
70. R Singh LA Cullen-McEwen KM Kett WM Boon J Dowling JF Bertram KM Moritz 2007 Prenatal corticosterone exposure results in altered AT1/AT2, nephron deficit and hypertension in the rat offspring J Physiol 579 503 513 17204493 10.1113/jphysiol.2006.125773 1:CAS:528:DC%2BD2sXjvVSgsbc%3D (Pubitemid 46351765)
71. MM Rodríguez AH Gómez CL Abitbol JJ Chandar S Duara GE Zilleruelo 2004 Histomorphometric analysis of postnatal glomerulogenesis in extremely preterm infants Pediatr Dev Pathol 7 17 25 15255031 10.1007/s10024-003-3029-2 (Pubitemid 38520228)
72. MM Rodriguez A Gomez C Abitbol J Chandar B Montané G Zilleruelo 2005 Comparative renal histomorphometry: a case study of oligonephropathy of prematurity Pediatr Nephrol 20 945 949 15856326 10.1007/s00467-004-1800-x (Pubitemid 40909266)
73. R Douglas-Denton KM Moritz JF Bertram EM Wintour 2002 Compensatory renal growth after unilateral nephrectomy in the ovine fetus J Am Soc Nephrol 13 406 410 11805169 (Pubitemid 34106283)
74. S Metsuyanim O Harari-Steinberg E Buzhor D Omer N Pode-Shakked H Ben-Hur R Halperin D Schneider B Dekel 2009 Expression of stem cell markers in the human fetal kidney PLoS ONE 4 e6709 19696931 10.1371/journal.pone.0006709
75. S Irion MC Nostro SJ Kattman GM Keller 2008 Directed differentiation of pluripotent stem cells: from developmental biology to therapeutic applications Cold Spring Harb Symp Quant Biol 73 101 110 19329573 10.1101/sqb.2008.73.065 1:CAS:528:DC%2BD1MXos1ertrk%3D
76. CE Murry G Keller 2008 Differentiation of embryonic stem cells to clinically relevant populations: lessons from embryonic development Cell 132 661 680 18295582 10.1016/j.cell.2008.02.008 1:CAS:528:DC%2BD1cXivVagtrc%3D (Pubitemid 351260059)
77. K Takahashi S Yamanaka 2006 Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors Cell 126 663 676 16904174 10.1016/j.cell.2006.07.024 1:CAS:528:DC%2BD28Xpt1aktbs%3D (Pubitemid 44233629)
78. T Graf 2002 Differentiation plasticity of hematopoietic cells Blood 99 3089 3101 11964270 10.1182/blood.V99.9.3089 1:CAS:528:DC%2BD38XjtlGru7g%3D (Pubitemid 34525285)
79. LH Bussmann A Schubert TP Vu Manh L De Andres SC Desbordes M Parra T Zimmermann F Rapino J Rodriguez-Ubreva E Ballestar T Graf 2009 A robust and highly efficient immune cell reprogramming system Cell Stem Cell 5 554 566 19896445 10.1016/j.stem.2009.10.004 1:CAS:528:DC%2BD1MXhsFKltLjP
80. Q Zhou J Brown A Kanarek J Rajagopal DA Melton 2008 In vivo reprogramming of adult pancreatic exocrine cells to β-cells Nature 455 627 632 18754011 10.1038/nature07314 1:CAS:528:DC%2BD1cXhtF2hsbvI
81. GA Challen I Ivan Bertoncello J Deane S Ricardo MH Little 2006 Kidney side population cells represent a non-haematopoietic but heterogeneous population with multilineage and renal potential J Amer Society Nephrol 17 1896 1912 10.1681/ASN.2005111228 1:CAS:528:DC%2BD28Xntlanur8%3D (Pubitemid 44036174)
82. T Yokoo T Ohashi JS Shen K Sakurai Y Miyazaki Y Utsunomiya M Takahashi Y Terada Y Eto T Kawamura N Osumi T Hosoya 2005 Human mesenchymal stem cells in rodent whole-embryo culture are reprogrammed to contribute to kidney tissues Proc Natl Acad Sci USA 102 3296 3300 15728383 10.1073/pnas.0406878102 1:CAS:528:DC%2BD2MXitl2ltb4%3D (Pubitemid 40328039)
83. M Elger H Hentschel J Litteral M Wellner T Kirsch FC Luft H Haller 2003 Nephrogenesis is induced by partial nephrectomy in the elasmobranch Leucoraja erinacea J Am Soc Nephrol 14 1506 1518 12761251 10.1097/01.ASN.0000067645.49562. 09 (Pubitemid 36687052)
84. R Reimschuessel RO Bennett EB May MM Lipsky 1990 Development of newly formed nephrons in the goldfish kidney following hexachlorobutadiene-induced nephrotoxicity Toxicol Pathol 18 32 38 2362986 1:CAS:528:DyaK3cXlvVKgsbg%3D (Pubitemid 20191996)
85. CJ Salice JS Rokous AS Kane R Reimschuessel 2001 New nephron development in goldfish (Carassius auratus) kidneys following repeated gentamicin-induced nephrotoxicosis Comp Med 51 56 59 11926303 1:STN:280:DC%2BD387ptlartw%3D%3D (Pubitemid 32259843)
86. SM Cormier TW Neiheisel RN Racine R Reimschuessel 1995 New nephron development in fish from polluted waters: A possible biomarker Ecotoxicology 4 157 168 10.1007/BF00116479 (Pubitemid 26451633)
87. Zhou W, Boucher RC, Bollig F, Englert C, Hildebrandt F (2010) Characterization of mesonephric development and regenaration using transgenic zebrafish. Am J Physiol Renal Physiol 229(5):F1040-F1047
88. N Watanabe M Kato N Suzuki C Inoue S Fedorova H Hashimoto S Maruyama S Matsuo Y Wakamatsu 2009 Kidney regeneration through nephron neogenesis in medaka Dev Growth Differ 51 135 143 19207184 10.1111/j.1440-169X.2009.01090.x
89. R Reimschuessel 2001 A fish model of renal regeneration and development ILAR J 42 285 291 11581520 1:STN:280:DC%2BD3Mrjt12jsA%3D%3D (Pubitemid 33708714)
90. F Rae K Woods T Sasmono N Campanale D Taylor D Ovchinnikov S Grimmond DA Hume S Ricardo MH Little 2007 Characterisation and trophic functions of murine embryonic macrophages based upon the use of a CSF-1R-EGFP transgene reporter Dev Biol 308 232 246 17597598 10.1016/j.ydbio.2007.05.027 1:CAS:528: DC%2BD2sXotlWqt7s%3D (Pubitemid 47087792)