Inflammation and oxidative stress are lower in physically fit and active adults

Scandinavian Journal of Medicine and Science in Sports

Volumn 23, Issue 2, 2013, Pages 215-223

  Shanely, R A ^a   Nieman, D C ^a   Henson, D A ^a   Jin, F ^a   Knab, A M ^a   Sha, W ^b  

^a APPALACHIAN STATE UNIVERSITY   (United States)

^b UNIVERSITY OF NORTH CAROLINA AT CHARLOTTE   (United States)

Author keywords

Antioxidant capacity; Body mass index; Cytokines; F2 isoprostanes; Granulocyte colony stimulating factor; Leukocytes; Perceived physical fitness

Indexed keywords

C REACTIVE PROTEIN; CYTOKINE; ISOPROSTANE DERIVATIVE;

ADOLESCENT; ADULT; AGED; ARTICLE; BLOOD; EXERCISE; FEMALE; FITNESS; HUMAN; INFLAMMATION; LEUKOCYTE COUNT; MALE; MIDDLE AGED; OXIDATIVE STRESS; PHYSIOLOGY; VERY ELDERLY;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; C-REACTIVE PROTEIN; CYTOKINES; EXERCISE; F2-ISOPROSTANES; FEMALE; HUMANS; INFLAMMATION; LEUKOCYTE COUNT; MALE; MIDDLE AGED; OXIDATIVE STRESS; PHYSICAL FITNESS; YOUNG ADULT;

EID: 84875617308     PISSN: 09057188     EISSN: 16000838     Source Type: Journal    
DOI: 10.1111/j.1600-0838.2011.01373.x     Document Type: Article

References (41)

1. Abramson JL, Vaccarino V . Relationship between physical activity and inflammation among apparently healthy middle-aged and older US adults. Arch Intern Med 2002: 162: 1286-1292.
2. Arsenault BJ, Cote M, Cartier A, Lemieux I, Despres JP, Ross R, Earnest CP, Blair SN, Church TS . Effect of exercise training on cardiometabolic risk markers among sedentary, but metabolically healthy overweight or obese post-menopausal women with elevated blood pressure. Atherosclerosis 2009: 207: 530-533.
3. Barreda DR, Hanington PC, Belosevic M . Regulation of myeloid development and function by colony stimulating factors. Dev Comp Immunol 2004: 28: 509-554.
4. Basu S . F2-isoprostanes in human health and diseases: from molecular mechanisms to clinical implications. Antioxid Redox Signal 2008: 10: 1405-1434.
5. Beavers KM, Brinkley TE, Nicklas BJ . Effect of exercise training on chronic inflammation. Clin Chim Acta 2010: 411: 785-793.
6. Booth FW, Gordon SE, Carlson CJ, Hamilton MT . Waging war on modern chronic diseases: primary prevention through exercise biology. J Appl Physiol 2000: 88: 774-787.
7. Campbell PT, Gross MD, Potter JD, Schmitz KH, Duggan C, Anne A, Ulrich CM . Effect of exercise on oxidative stress: a 12-month randomized, controlled trial. Med Sci Sports Exerc 2010: 42: 1448-1453.
8. Christiansen T, Paulsen SK, Bruun JM, Pedersen SB, Richelsen B . Exercise training versus diet-induced weight-loss on metabolic risk factors and inflammatory markers in obese subjects: a 12-week randomized intervention study. Am J Physiol Endocrinol Metab 2010: 298: E824-E831.
9. Church TS, Earnest CP, Thompson AM, Priest E, Rodarte RQ, Sanders T, Ross R, Blair SN . Exercise without weight loss does not reduce C-reactive protein: the INFLAME Study. Med Sci Sports Exerc 2010: 42: 708-716.
10. Colbert LH, Visser M, Simonsick EM, Tracy RP, Newman AB, Kritchevsky SB, Pahor M, Taaffe DR, Brach J, Rubin S, Harris TB . Physical activity, exercise, and inflammatory markers in older adults: findings from the Health, Aging and Body Composition Study. J Am Geriatr Soc 2004: 52: 1098-1104.
11. Danesh J, Collins R, Appleby P, Peto R . Association of fibrinogen, C-reactive protein, albumin, or leukocyte count with coronary heart disease: meta-analyses of Prospective Studies. JAMA 1998: 279: 1477-1482.
12. Elosua R, Bartali B, Ordovas JM, Corsi AM, Lauretani F, Ferrucci L . Association between physical activity, physical performance, and inflammatory biomarkers in an elderly population: the InCHIANTI study. J Gerontol A Biol Sci Med Sci 2005: 60: 760-767.
13. Esmaillzadeh A, Kimiagar M, Mehrabi Y, Azadbakht L, Hu FB, Willett WC . Fruit and vegetable intakes, C-reactive protein, and the metabolic syndrome. Am J Clin Nutr 2006: 84: 1489-1497.
14. Fisher-Wellman K, Bell HK, Bloomer RJ . Oxidative stress and antioxidant defense mechanisms linked to exercise during cardiopulmonary and metabolic disorders. Oxid Med Cell Longev 2009: 2: 43-51.
15. Ford ES . Does exercise reduce inflammation? Physical activity and C-reactive protein among U.S. adults. Epidemiology 2002: 13: 561-568.
16. Gerber M, Brand S, Holsboer-Trachsler E, Puhse U . Fitness and exercise as correlates of sleep complaints: is it all in our minds? Med Sci Sports Exerc 2010: 42: 893-901.
17. Gustafson B . Adipose tissue, inflammation and atherosclerosis. J Atheroscler Thromb 2010: 17: 332-341.
18. Heinz SA, Henson DA, Nieman DC, Austin MD, Jin F . A 12-week supplementation with quercetin does not affect natural killer cell activity, granulocyte oxidative burst activity or granulocyte phagocytosis in female human subjects. Br J Nutr 2010: 104: 849-857.
19. Holt EM, Steffen LM, Moran A, Basu S, Steinberger J, Ross JA, Hong CP, Sinaiko AR . Fruit and vegetable consumption and its relation to markers of inflammation and oxidative stress in adolescents. J Am Diet Assoc 2009: 109: 414-421.
20. Kadoglou NP, Iliadis F, Angelopoulou N, Perrea D, Ampatzidis G, Liapis CD, Alevizos M . The anti-inflammatory effects of exercise training in patients with type 2 diabetes mellitus. Eur J Cardiovasc Prev Rehabil 2007: 14: 837-843.
21. Kelley GA, Kelley KS . Effects of aerobic exercise on C-reactive protein, body composition, and maximum oxygen consumption in adults: a meta-analysis of randomized controlled trials. Metabolism 2006: 55: 1500-1507.
22. King DE, Carek P, Mainous AG, 3rd, Pearson WS . Inflammatory markers and exercise: differences related to exercise type. Med Sci Sports Exerc 2003: 35: 575-581.
23. Kohut ML, McCann DA, Russell DW, Konopka DN, Cunnick JE, Franke WD, Castillo MC, Reighard AE, Vanderah E . Aerobic exercise, but not flexibility/resistance exercise, reduces serum IL-18, CRP, and IL-6 independent of beta-blockers, BMI, and psychosocial factors in older adults. Brain Behav Immun 2006: 20: 201-209.
24. Milton K, Bull FC, Bauman A . Reliability and validity testing of a single-item physical activity measure. Br J Sports Med 2011: 45: 203-208.
25. Morrow JD . Quantification of isoprostanes as indices of oxidant stress and the risk of atherosclerosis in humans. Arterioscler Thromb Vasc Biol 2005: 25: 279-286.
26. National Center for Health Statistics (U.S.). National Health Interview Survey : research for the 1995-2004 redesign. Hyattsville, MD: U.S. Dept. of Health and Human Services, Centers for Disease Control and Prevention, National Center for Health Statistics, 1999.
27. Nieman DC, Dumke CL, Henson DA, McAnulty SR, Gross SJ, Lind RH . Muscle damage is linked to cytokine changes following a 160-km race. Brain Behav Immun 2005: 19: 398-403.
28. Nieman DC, Henson DA, Davis JM, Dumke CL, Gross SJ, Jenkins DP, Murphy EA, Carmichael MD, Quindry JC, McAnulty SR, McAnulty LS, Utter AC, Mayer EP . Quercetin ingestion does not alter cytokine changes in athletes competing in the Western States Endurance Run. J Interferon Cytokine Res 2007: 27: 1003-1011.
29. Pitsavos C, Panagiotakos DB, Chrysohoou C, Kavouras S, Stefanadis C . The associations between physical activity, inflammation, and coagulation markers, in people with metabolic syndrome: the ATTICA study. Eur J Cardiovasc Prev Rehabil 2005: 12: 151-158.
30. Plante TG, Lantis A, Checa G . The influence of perceived versus aerobic fitness on psychological health and physiological stress responsivity. Int J Stress Manage 1998: 5: 141-156.
31. Schmitz KH, Warren M, Rundle AG, Williams NI, Gross MD, Kurzer MS . Exercise effect on oxidative stress is independent of change in estrogen metabolism. Cancer Epidem Biomar 2008: 17: 220-223.
32. Selvin E, Paynter NP, Erlinger TP . The effect of weight loss on C-reactive protein: a systematic review. Arch Intern Med 2007: 167: 31-39.
33. Shanely RA, Knab AM, Nieman DC, Jin F, McAnulty SR, Landram MJ . Quercetin supplementation does not alter antioxidant status in humans. Free Radical Res 2010: 44: 224-231.
34. Stewart LK, Earnest CP, Blair SN, Church TS . Effects of different doses of physical activity on c-reactive protein among women. Med Sci Sports Exerc 2010: 42: 701-707.
35. Stewart LK, Flynn MG, Campbell WW, Craig BA, Robinson JP, Timmerman KL, McFarlin BK, Coen PM, Talbert E . The influence of exercise training on inflammatory cytokines and C-reactive protein. Med Sci Sports Exerc 2007: 39: 1714-1719.
36. Suzuki K, Nakaji S, Yamada M, Totsuka M, Sato K, Sugawara K . Systemic inflammatory response to exhaustive exercise. Cytokine kinetics. Exerc Immunol Rev 2002: 8: 6-48.
37. Thompson D, Markovitch D, Betts JA, Mazzatti D, Turner J, Tyrrell RM . Time course of changes in inflammatory markers during a 6-mo exercise intervention in sedentary middle-aged men: a randomized-controlled trial. J Appl Physiol 2010: 108: 769-779.
38. Urakawa H, Katsuki A, Sumida Y, Gabazza EC, Murashima S, Morioka K, Maruyama N, Kitagawa N, Tanaka T, Hori Y, Nakatani K, Yano Y, Adachi Y . Oxidative stress is associated with adiposity and insulin resistance in men. J Clin Endocrinol Metab 2003: 88: 4673-4676.
39. Vincent HK, Taylor AG . Biomarkers and potential mechanisms of obesity-induced oxidant stress in humans. Int J Obes (Lond) 2006: 30: 400-418.
40. Voss P, Siems W . Clinical oxidation parameters of aging. Free Radical Res 2006: 40: 1339-1349.
41. Yamada M, Suzuki K, Kudo S, Totsuka M, Nakaji S, Sugawara K . Raised plasma G-CSF and IL-6 after exercise may play a role in neutrophil mobilization into the circulation. J Appl Physiol 2002: 92: 1789-1794.