-
1
-
-
1542398693
-
Randomized phase II study of multiple dose levels of CCI-779, a novel mammalian target of rapamycin kinase inhibitor, in patients with advanced refractory renal cell carcinoma
-
DOI 10.1200/JCO.2004.08.185
-
Atkins M. B., Hidalgo M., Stadler W. M., Logan T. F., Dutcher J. P., Hudes G. R., Park Y., Liou S. H., Marshall B., Boni J. P., Dukart G., Sherman M. L., Randomized phase II study of multiple dose levels of CCI-779, a novel mammalian target of rapamycin kinase inhibitor, in patients with advanced refractory renal cell carcinoma. Journal of Clinical Oncology 2004 22 5 909 918 2-s2.0-1542398693 10.1200/JCO.2004.08.185 (Pubitemid 41103603)
-
(2004)
Journal of Clinical Oncology
, vol.22
, Issue.5
, pp. 909-918
-
-
Atkins, M.B.1
Hidalgo, M.2
Stadler, W.M.3
Logan, T.F.4
Dutcher, J.P.5
Hudes, G.R.6
Park, Y.7
Liou, S.-H.8
Marshall, B.9
Boni, J.P.10
Dukart, G.11
Sherman, M.L.12
-
2
-
-
34249779568
-
Temsirolimus, interferon alfa, or both for advanced renal-cell carcinoma
-
DOI 10.1056/NEJMoa066838
-
Hudes G., Carducci M., Tomczak P., Dutcher J., Figlin R., Kapoor A., Staroslawska E., Sosman J., McDermott D., Bodrogi I., Kovacevic Z., Lesovoy V., Schmidt-Wolf I. G., Barbarash O., Gokmen E., O'Toole T., Lustgarten S., Moore L., Motzer R. J., Temsirolimus, interferon alfa, or both for advanced renal-cell carcinoma. The New England Journal of Medicine 2007 356 2271 2281 (Pubitemid 46849157)
-
(2007)
New England Journal of Medicine
, vol.356
, Issue.22
, pp. 2271-2281
-
-
Hudes, G.1
Carducci, M.2
Tomczak, P.3
Dutcher, J.4
Figlin, R.5
Kapoor, A.6
Staroslawska, E.7
Sosman, J.8
McDermott, D.9
Bodrogi, I.10
Kovacevic, Z.11
Lesovoy, V.12
Schmidt-Wolf, I.G.H.13
Barbarash, O.14
Gokmen, E.15
O'Toole, T.16
Lustgarten, S.17
Moore, L.18
Motzer, R.J.19
-
3
-
-
79959610128
-
Utility of mTOR inhibition in hematologic malignancies
-
2-s2.0-79959610128 10.1634/theoncologist.2010-0318
-
Younes A., Samad N., Utility of mTOR inhibition in hematologic malignancies. Oncologist 2011 16 6 730 741 2-s2.0-79959610128 10.1634/theoncologist.2010-0318
-
(2011)
Oncologist
, vol.16
, Issue.6
, pp. 730-741
-
-
Younes, A.1
Samad, N.2
-
4
-
-
10244260355
-
Combination of the mTOR inhibitor rapamycin and CC-5013 has synergistic activity in multiple myeloma
-
DOI 10.1182/blood-2004-06-2281
-
Raje N., Kumar S., Hideshima T., Ishitsuka K., Chauhan D., Mitsiades C., Podar K., Le Gouill S., Richardson P., Munshi N. C., Stirling D. I., Antin J. H., Anderson K. C., Combination of the mTOR inhibitor rapamycin and CC-5013 has synergistic activity in multiple myeloma. Blood 2004 104 13 4188 4193 2-s2.0-10244260355 10.1182/blood-2004-06-2281 (Pubitemid 39620173)
-
(2004)
Blood
, vol.104
, Issue.13
, pp. 4188-4193
-
-
Raje, N.1
Kumar, S.2
Hideshima, T.3
Ishitsuka, K.4
Chauhan, D.5
Mitsiades, C.6
Podar, K.7
Le Gouill, S.8
Richardson, P.9
Munshi, N.C.10
Stirling, D.I.11
Antin, J.H.12
Anderson, K.C.13
-
5
-
-
33845898823
-
Farnesyltransferase inhibitors and rapamycin in the treatment of multiple myeloma
-
DOI 10.2174/138920106779116838
-
Zangari M., Cavallo F., Tricot G., Farnesyltransferase inhibitors and rapamycin in the treatment of multiple myeloma. Current Pharmaceutical Biotechnology 2006 7 6 449 453 2-s2.0-33845898823 10.2174/138920106779116838 (Pubitemid 46017536)
-
(2006)
Current Pharmaceutical Biotechnology
, vol.7
, Issue.6
, pp. 449-453
-
-
Zangari, M.1
Cavallo, F.2
Tricot, G.3
-
6
-
-
10244229652
-
In vivo antitumor effects of the mTOR inhibitor CCI-779 against human multiple myeloma cells in a xenograft model
-
DOI 10.1182/blood-2004-03-1153
-
Frost P., Moatamed F., Hoang B., Shi Y., Gera J., Yan H., Frost P., Gibbons J., Lichtenstein A., In vivo antitumor effects of the mTOR inhibitor CCI-779 against human multiple myeloma cells in a xenograft model. Blood 2004 104 13 4181 4187 2-s2.0-10244229652 10.1182/blood-2004-03-1153 (Pubitemid 39620172)
-
(2004)
Blood
, vol.104
, Issue.13
, pp. 4181-4187
-
-
Frost, P.1
Moatamed, F.2
Hoang, B.3
Shi, Y.4
Gera, J.5
Yan, H.6
Frost, P.7
Gibbons, J.8
Lichtenstein, A.9
-
7
-
-
17444440115
-
Rapamycin sensitizes multiple myeloma cells to apoptosis induced by dexamethasone
-
DOI 10.1182/blood-2003-05-1543
-
Strömberg T., Dimberg A., Hammarberg A., Carlson K., Österborg A., Nilsson K., Jernberg-Wiklund H., Rapamycin sensitizes multiple myeloma cells to apoptosis induced by dexamethasone. Blood 2004 103 8 3138 3147 2-s2.0-17444440115 10.1182/blood-2003-05-1543 (Pubitemid 38451692)
-
(2004)
Blood
, vol.103
, Issue.8
, pp. 3138-3147
-
-
Stromberg, T.1
Dimberg, A.2
Hammarberg, A.3
Carlson, K.4
Osterborg, A.5
Nilsson, K.6
Jernberg-Wiklund, H.7
-
8
-
-
33644516582
-
Mechanism by which mammalian target of rapamycin inhibitors sensitize multiple myeloma cells to dexamethasone-induced apoptosis
-
2-s2.0-33644516582 10.1158/0008-5472.CAN-05-2447
-
Yan H., Frost P., Shi Y., Hoang B., Sharma S., Fisher M., Gera J., Lichtenstein A., Mechanism by which mammalian target of rapamycin inhibitors sensitize multiple myeloma cells to dexamethasone-induced apoptosis. Cancer Research 2006 66 4 2305 2313 2-s2.0-33644516582 10.1158/0008-5472.CAN-05-2447
-
(2006)
Cancer Research
, vol.66
, Issue.4
, pp. 2305-2313
-
-
Yan, H.1
Frost, P.2
Shi, Y.3
Hoang, B.4
Sharma, S.5
Fisher, M.6
Gera, J.7
Lichtenstein, A.8
-
9
-
-
34147104488
-
AKT activity regulates the ability of mTOR inhibitors to prevent angiogenesis and VEGF expression in multiple myeloma cells
-
DOI 10.1038/sj.onc.1210019, PII 1210019
-
Frost P., Shi Y., Hoang B., Lichtenstein A., AKT activity regulates the ability of mTOR inhibitors to prevent angiogenesis and VEGF expression in multiple myeloma cells. Oncogene 2007 26 16 2255 2262 2-s2.0-34147104488 10.1038/sj.onc.1210019 (Pubitemid 46572812)
-
(2007)
Oncogene
, vol.26
, Issue.16
, pp. 2255-2262
-
-
Frost, P.1
Shi, Y.2
Hoang, B.3
Lichtenstein, A.4
-
10
-
-
33750483896
-
The antitumor effects of sunitinib (formerly SU11248) against a variety of human hematologic malignancies: Enhancement of growth inhibition via inhibition of mammalian target of rapamcycin signaling
-
DOI 10.1158/1535-7163.MCT-06-0071
-
Ikezoe T., Nishioka C., Tasaka T., Yang Y., Komatsu N., Togitani K., Koeffler H. P., Taguchi H., The antitumor effects of sunitinib (formerly SU11248) against a variety of human hematologic malignancies: enhancement of growth inhibition via inhibition of mammalian target of rapamcycin signaling. Molecular Cancer Therapeutics 2006 5 10 2522 2530 2-s2.0-33750483896 10.1158/1535-7163.MCT-06-0071 (Pubitemid 44650916)
-
(2006)
Molecular Cancer Therapeutics
, vol.5
, Issue.10
, pp. 2522-2530
-
-
Ikezoe, T.1
Nishioka, C.2
Tasaka, T.3
Yang, Y.4
Komatsu, N.5
Togitani, K.6
Koeffler, H.P.7
Taguchi, H.8
-
11
-
-
0037013205
-
S6K and phosphorylation of 4E-BP1 following exposure of multiple myeloma tumor cells to interleukin-6
-
DOI 10.1074/jbc.M200043200
-
Shi Y., Hsu J. H., Hu L., Gera J., Lichtenstein A., Signal pathways involved in activation of p70S6K and phosphorylation of 4E-BP1 following exposure of multiple myeloma tumor cells to interleukin-6. Journal of Biological Chemistry 2002 277 18 15712 15720 2-s2.0-0037013205 10.1074/jbc.M200043200 (Pubitemid 34967845)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.18
, pp. 15712-15720
-
-
Shi, Y.1
Hsu, J.-H.2
Hu, L.3
Gera, J.4
Lichtenstein, A.5
-
12
-
-
0036735346
-
Enhanced sensitivity of multiple myeloma cells containing PTEN mutations to CCI-779
-
Shi Y., Gera J., Hu L., Hsu J. H., Bookstein R., Li W., Lichtenstein A., Enhanced sensitivity of multiple myeloma cells containing PTEN mutations to CCI-779. Cancer Research 2002 62 17 5027 5034 2-s2.0-0036735346 (Pubitemid 34984430)
-
(2002)
Cancer Research
, vol.62
, Issue.17
, pp. 5027-5034
-
-
Shi, Y.1
Gera, J.2
Hu, L.3
Hsu, J.-H.4
Bookstein, R.5
Li, W.6
Lichtenstein, A.7
-
13
-
-
23944481410
-
Phase II trial of single-agent temsirolimus (CCI-779) for relapsed mantle cell lymphoma
-
DOI 10.1200/JCO.2005.13.466
-
Witzig T. E., Geyer S. M., Ghobrial I., Inwards D. J., Fonseca R., Kurtin P., Ansell S. M., Luyun R., Flynn P. J., Morton R. F., Dakhil S. R., Gross H., Kaufmann S. H., Phase II trial of single-agent temsirolimus (CCI-779) for relapsed mantle cell lymphoma. Journal of Clinical Oncology 2005 23 23 5347 5356 2-s2.0-23944481410 10.1200/JCO.2005.13.466 (Pubitemid 46206988)
-
(2005)
Journal of Clinical Oncology
, vol.23
, Issue.23
, pp. 5347-5356
-
-
Witzig, T.E.1
Geyer, S.M.2
Ghobrial, I.3
Inwards, D.J.4
Fonseca, R.5
Kurtin, P.6
Ansell, S.M.7
Luyun, R.8
Flynn, P.J.9
Morton, R.F.10
Dakhil, S.R.11
Gross, H.12
Kaufmann, S.H.13
-
14
-
-
78149239933
-
Temsirolimus has activity in non-mantle cell non-Hodgkin's lymphoma subtypes: The University of Chicago phase II consortium
-
2-s2.0-78149239933 10.1200/JCO.2010.29.2813
-
Smith S. M., van Besien K., Karrison T., Dancey J., McLaughlin P., Younes A., Smith S., Stiff P., Lester E., Modi S., Doyle L. A., Vokes E. E., Pro B., Temsirolimus has activity in non-mantle cell non-Hodgkin's lymphoma subtypes: the University of Chicago phase II consortium. Journal of Clinical Oncology 2010 28 31 4740 4746 2-s2.0-78149239933 10.1200/JCO.2010.29.2813
-
(2010)
Journal of Clinical Oncology
, vol.28
, Issue.31
, pp. 4740-4746
-
-
Smith, S.M.1
Van Besien, K.2
Karrison, T.3
Dancey, J.4
McLaughlin, P.5
Younes, A.6
Smith, S.7
Stiff, P.8
Lester, E.9
Modi, S.10
Doyle, L.A.11
Vokes, E.E.12
Pro, B.13
-
15
-
-
1642535431
-
AKT Activity Determines Sensitivity to Mammalian Target of Rapamycin (mTOR) Inhibitors by Regulating Cyclin D1 and c-myc Expression
-
DOI 10.1074/jbc.M309999200
-
Gera J. F., Mellinghoff I. K., Shi Y., Rettig M. B., Tran C., Hsu J. H., Sawyers C. L., Lichtenstein A. K., AKT activity determines sensitivity to mammalian target of rapamycin (mTOR) inhibitors by regulating cyclin D1 and c-myc expression. Journal of Biological Chemistry 2004 279 4 2737 2746 2-s2.0-1642535431 10.1074/jbc.M309999200 (Pubitemid 38114263)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.4
, pp. 2737-2746
-
-
Gera, J.F.1
Mellinghoff, I.K.2
Shi, Y.3
Rettig, M.B.4
Tran, C.5
Hsu, J.-H.6
Sawyers, C.L.7
Lichtenstein, A.K.8
-
16
-
-
0036894711
-
ELAV/Hu proteins inhibit p27 translation via an IRES element in the p27 5′UTR
-
DOI 10.1101/gad.248902
-
Kullmann M., Göpfert U., Siewe B., Hengst L., ELAV/Hu proteins inhibit p27 translation via an IRES element in the p27 5′UTR. Genes and Development 2002 16 23 3087 3099 2-s2.0-0036894711 10.1101/gad.248902 (Pubitemid 35424195)
-
(2002)
Genes and Development
, vol.16
, Issue.23
, pp. 3087-3099
-
-
Kullmann, M.1
Gopfert, U.2
Siewe, B.3
Hengst, L.4
-
17
-
-
0034947868
-
Control of cyclin-dependent kinase inhibitor p27 expression by cap-independent translation
-
DOI 10.1128/MCB.21.15.4960-4967.2001
-
Miskimins W. K., Wang G., Hawkinson M., Miskimins R., Control of cyclin-dependent kinase inhibitor p27 expression by cap-independent translation. Molecular and Cellular Biology 2001 21 15 4960 4967 2-s2.0-0034947868 10.1128/MCB.21.15.4960-4967.2001 (Pubitemid 32656394)
-
(2001)
Molecular and Cellular Biology
, vol.21
, Issue.15
, pp. 4960-4967
-
-
Miskimins, W.K.1
Wang, G.2
Hawkinson, M.3
Miskimins, R.4
-
18
-
-
0036735298
-
Proteasome inhibitor PS-341 inhibits human myeloma cell growth in vivo and prolongs survival in a murine model
-
LeBlanc R., Catley L. P., Hideshima T., Lentzsch S., Mitsiades C. S., Mitsiades N., Neuberg D., Goloubeva O., Pien C. S., Adams J., Gupta D., Richardson P. G., Munshi N. C., Anderson K. C., Proteasome inhibitor PS-341 inhibits human myeloma cell growth in vivo and prolongs survival in a murine model. Cancer Research 2002 62 17 4996 5000 2-s2.0-0036735298 (Pubitemid 34984425)
-
(2002)
Cancer Research
, vol.62
, Issue.17
, pp. 4996-5000
-
-
LeBlanc, R.1
Catley, L.P.2
Hideshima, T.3
Lentzsch, S.4
Mitsiades, C.S.5
Mitsiades, N.6
Neuberg, D.7
Goloubeva, O.8
Pien, C.S.9
Adams, J.10
Gupta, D.11
Richardson, P.G.12
Munshi, N.C.13
Anderson, K.C.14
-
19
-
-
17944377486
-
Enhanced sensitivity of PTEN-deficient tumors to inhibition of FRAP/mTOR
-
DOI 10.1073/pnas.171076798
-
Neshat M. S., Mellinghoff I. K., Tran C., Stiles B., Thomas G., Petersen R., Frost P., Gibbons J. J., Wu H., Sawyers C. L., Enhanced sensitivity of PTEN-deficient tumors to inhibition of FRAP/mTOR. Proceedings of the National Academy of Sciences of the United States of America 2001 98 18 10314 10319 2-s2.0-17944377486 10.1073/pnas.171076798 (Pubitemid 32803017)
-
(2001)
Proceedings of the National Academy of Sciences of the United States of America
, vol.98
, Issue.18
, pp. 10314-10319
-
-
Neshat, M.S.1
Mellinghoff, I.K.2
Tran, C.3
Stiles, B.4
Thomas, G.5
Petersen, R.6
Frost, P.7
Gibbons, J.J.8
Wu, H.9
Sawyers, C.L.10
-
20
-
-
58149490636
-
Regulation of D-cyclin translation inhibition in myeloma cells treated with mammalian target of rapamycin inhibitors: Rationale for combined treatment with extracellular signal-regulated kinase inhibitors and rapamycin
-
2-s2.0-58149490636 10.1158/1535-7163.MCT-08-0254
-
Frost P., Shi Y., Hoang B., Gera J., Lichtenstein A., Regulation of D-cyclin translation inhibition in myeloma cells treated with mammalian target of rapamycin inhibitors: rationale for combined treatment with extracellular signal-regulated kinase inhibitors and rapamycin. Molecular Cancer Therapeutics 2009 8 1 83 93 2-s2.0-58149490636 10.1158/1535-7163.MCT-08-0254
-
(2009)
Molecular Cancer Therapeutics
, vol.8
, Issue.1
, pp. 83-93
-
-
Frost, P.1
Shi, Y.2
Hoang, B.3
Gera, J.4
Lichtenstein, A.5
-
21
-
-
55749084366
-
ABT-263 and rapamycin act cooperatively to kill lymphoma cells in vitro and in vivo
-
2-s2.0-55749084366 10.1158/1535-7163.MCT-08-0268
-
Ackler S., Xiao Y., Mitten M. J., Foster K., Oleksijew A., Refici M., Schlessinger S., Wang B., Chemburkar S. R., Bauch J., Tse C., Frost D. J., Fesik S. W., Rosenberg S. H., Elmore S. W., Shoemaker A. R., ABT-263 and rapamycin act cooperatively to kill lymphoma cells in vitro and in vivo. Molecular Cancer Therapeutics 2008 7 10 3265 3274 2-s2.0-55749084366 10.1158/1535-7163.MCT-08- 0268
-
(2008)
Molecular Cancer Therapeutics
, vol.7
, Issue.10
, pp. 3265-3274
-
-
Ackler, S.1
Xiao, Y.2
Mitten, M.J.3
Foster, K.4
Oleksijew, A.5
Refici, M.6
Schlessinger, S.7
Wang, B.8
Chemburkar, S.R.9
Bauch, J.10
Tse, C.11
Frost, D.J.12
Fesik, S.W.13
Rosenberg, S.H.14
Elmore, S.W.15
Shoemaker, A.R.16
-
22
-
-
34547911389
-
Cap-independent translation through the p27 5′-UTR
-
DOI 10.1093/nar/gkm512
-
Jiang H., Coleman J., Miskimins R., Srinivasan R., Miskimins W. K., Cap-independent translation through the p27 5′-UTR. Nucleic Acids Research 2007 35 14 4767 4778 2-s2.0-34547911389 10.1093/nar/gkm512 (Pubitemid 47250348)
-
(2007)
Nucleic Acids Research
, vol.35
, Issue.14
, pp. 4767-4778
-
-
Jiang, H.1
Coleman, J.2
Miskimins, R.3
Srinivasan, R.4
Miskimins, W.K.5
-
23
-
-
61349141302
-
Active-site inhibitors of mTOR target rapamycin-resistant outputs of mTORC1 and mTORC2
-
ARTICLE E38 2-s2.0-65249156511 10.1371/journal.pbio.1000038
-
Feldman M. E., Apsel B., Uotila A., Loewith R., Knight Z. A., Ruggero D., Shokat K. M., Active-site inhibitors of mTOR target rapamycin-resistant outputs of mTORC1 and mTORC2. PLoS Biology 2009 7 2, article e38 2-s2.0-65249156511 10.1371/journal.pbio.1000038
-
(2009)
PLoS Biology
, vol.7
, Issue.2
-
-
Feldman, M.E.1
Apsel, B.2
Uotila, A.3
Loewith, R.4
Knight, Z.A.5
Ruggero, D.6
Shokat, K.M.7
-
24
-
-
76549107351
-
Beyond rapalog therapy: Preclinical pharmacology and antitumor activity of WYE-125132, an ATP-competitive and specific inhibitor of mTORC1 and mTORC2
-
2-s2.0-76549107351 10.1158/0008-5472.CAN-09-2340
-
Yu K., Shi C., Toral-Barza L., Lucas J., Shor B., Kim J. E., Zhang W. G., Mahoney R., Gaydos C., Tardio L., Kim S. K., Conant R., Curran K., Kaplan J., Verheijen J., Ayral-Kaloustian S., Mansour T. S., Abraham R. T., Zask A., Gibbons J. J., Beyond rapalog therapy: preclinical pharmacology and antitumor activity of WYE-125132, an ATP-competitive and specific inhibitor of mTORC1 and mTORC2. Cancer Research 2010 70 2 621 631 2-s2.0-76549107351 10.1158/0008-5472.CAN-09-2340
-
(2010)
Cancer Research
, vol.70
, Issue.2
, pp. 621-631
-
-
Yu, K.1
Shi, C.2
Toral-Barza, L.3
Lucas, J.4
Shor, B.5
Kim, J.E.6
Zhang, W.G.7
Mahoney, R.8
Gaydos, C.9
Tardio, L.10
Kim, S.K.11
Conant, R.12
Curran, K.13
Kaplan, J.14
Verheijen, J.15
Ayral-Kaloustian, S.16
Mansour, T.S.17
Abraham, R.T.18
Zask, A.19
Gibbons, J.J.20
more..
-
25
-
-
78649471733
-
Targeting TORC2 in multiple myeloma with a new mTOR kinase inhibitor
-
2-s2.0-78649471733 10.1182/blood-2010-05-285726
-
Hoang B., Frost P., Shi Y., Belanger E., Benavides A., Pezeshkpour G., Cappia S., Guglielmelli T., Gera J., Lichtenstein A., Targeting TORC2 in multiple myeloma with a new mTOR kinase inhibitor. Blood 2010 116 22 4560 4568 2-s2.0-78649471733 10.1182/blood-2010-05-285726
-
(2010)
Blood
, vol.116
, Issue.22
, pp. 4560-4568
-
-
Hoang, B.1
Frost, P.2
Shi, Y.3
Belanger, E.4
Benavides, A.5
Pezeshkpour, G.6
Cappia, S.7
Guglielmelli, T.8
Gera, J.9
Lichtenstein, A.10
-
26
-
-
79952216582
-
Reduced VEGF production, angiogenesis, and vascular regrowth contribute to the antitumor properties of dual mTORC1/mTORC2 inhibitors
-
2-s2.0-79952216582 10.1158/0008-5472.CAN-10-3126
-
Falcon B. L., Barr S., Gokhale P. C., Chou J., Fogarty J., Depeille P., Miglarese M., Epstein D. M., M D. M., Reduced VEGF production, angiogenesis, and vascular regrowth contribute to the antitumor properties of dual mTORC1/mTORC2 inhibitors. Cancer Research 2011 71 5 1573 1583 2-s2.0-79952216582 10.1158/0008-5472.CAN-10-3126
-
(2011)
Cancer Research
, vol.71
, Issue.5
, pp. 1573-1583
-
-
Falcon, B.L.1
Barr, S.2
Gokhale, P.C.3
Chou, J.4
Fogarty, J.5
Depeille, P.6
Miglarese, M.7
Epstein, D.M.M.M.D.8
-
27
-
-
33745242315
-
Antiangiogenic potential of the mammalian target of rapamycin inhibitor temsirolimus
-
DOI 10.1158/0008-5472.CAN-05-2825
-
Del Bufalo D., Ciuffreda L., Trisciuoglio D., Desideri M., Cognetti F., Zupi G., Milella M., Antiangiogenic potential of the mammalian target of rapamycin inhibitor temsirolimus. Cancer Research 2006 66 11 5549 5554 2-s2.0-33745242315 10.1158/0008-5472.CAN-05-2825 (Pubitemid 43927103)
-
(2006)
Cancer Research
, vol.66
, Issue.11
, pp. 5549-5554
-
-
Del Bufalo, D.1
Ciuffreda, L.2
Trisciuoglio, D.3
Desideri, M.4
Cognetti, F.5
Zupi, G.6
Milella, M.7
-
28
-
-
56449087509
-
Palomid 529, a novel small-molecule drug, is a TORC1/TORC2 inhibitor that reduces tumor growth, tumor angiogenesis, and vascular permeability
-
2-s2.0-56449087509 10.1158/0008-5472.CAN-08-2058
-
Xue Q., Hopkins B., Perruzzi C., Udayakumar D., Sherris D., Benjamin L. E., Palomid 529, a novel small-molecule drug, is a TORC1/TORC2 inhibitor that reduces tumor growth, tumor angiogenesis, and vascular permeability. Cancer Research 2008 68 22 9551 9557 2-s2.0-56449087509 10.1158/0008-5472.CAN-08-2058
-
(2008)
Cancer Research
, vol.68
, Issue.22
, pp. 9551-9557
-
-
Xue, Q.1
Hopkins, B.2
Perruzzi, C.3
Udayakumar, D.4
Sherris, D.5
Benjamin, L.E.6
-
29
-
-
84863232885
-
Macrophage-induced tumor angiogenesis is regulated by the TSC2-mTOR pathway
-
10.1158/0008-5472.CAN-11-2684
-
Chen W., Ma T., Shen X. N., Xia X. F., Xu G. D., Bai X. L., Liang T. B., Macrophage-induced tumor angiogenesis is regulated by the TSC2-mTOR pathway. Cancer Research 2012 72 1363 1372 10.1158/0008-5472.CAN-11-2684
-
(2012)
Cancer Research
, vol.72
, pp. 1363-1372
-
-
Chen, W.1
Ma, T.2
Shen, X.N.3
Xia, X.F.4
Xu, G.D.5
Bai, X.L.6
Liang, T.B.7
-
30
-
-
0031869662
-
Translation of vascular endothelial growth factor mRNA by internal ribosome entry: Implications for translation under hypoxia
-
Stein I., Itin A., Einat P., Skaliter R., Grossman Z., Keshet E., Translation of vascular endothelial growth factor mRNA by internal ribosome entry: implications for translation under hypoxia. Molecular and Cellular Biology 1998 18 6 3112 3119 2-s2.0-0031869662 (Pubitemid 28240484)
-
(1998)
Molecular and Cellular Biology
, vol.18
, Issue.6
, pp. 3112-3119
-
-
Stein, I.1
Itin, A.2
Einat, P.3
Skaliter, R.4
Grossman, Z.5
Keshet, E.6
-
31
-
-
33646884832
-
Assessing IRES activity in the HIF-1α and other cellular 5′ UTRs
-
DOI 10.1261/rna.2320506
-
Bert A. G., Grépin R., Vadas M. A., Goodall G. J., Assessing IRES activity in the HIF-1 α and other cellular 5′ UTRs. RNA 2006 12 6 1074 1083 2-s2.0-33646884832 10.1261/rna.2320506 (Pubitemid 43788125)
-
(2006)
RNA
, vol.12
, Issue.6
, pp. 1074-1083
-
-
Bert, A.G.1
Grepin, R.2
Vadas, M.A.3
Goodall, G.J.4
-
32
-
-
47749141892
-
Hypoxia-mediated selective mRNA translation by an internal ribosome entry site-independent mechanism
-
2-s2.0-47749141892 10.1074/jbc.M710079200
-
Young R. M., Wang S. J., Gordan J. D., Ji X., Liebhaber S. A., Simon M. C., Hypoxia-mediated selective mRNA translation by an internal ribosome entry site-independent mechanism. Journal of Biological Chemistry 2008 283 24 16309 16319 2-s2.0-47749141892 10.1074/jbc.M710079200
-
(2008)
Journal of Biological Chemistry
, vol.283
, Issue.24
, pp. 16309-16319
-
-
Young, R.M.1
Wang, S.J.2
Gordan, J.D.3
Ji, X.4
Liebhaber, S.A.5
Simon, M.C.6
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