Cap-independent translation through the p27 5′-UTR

Nucleic Acids Research

Volumn 35, Issue 14, 2007, Pages 4767-4778

  Jiang, Hong ^a,b   Coleman, Jennifer ^b   Miskimins, Robin ^b   Srinivasan, Rekha ^b   Miskimins, W Keith ^a,b  

^a SANFORD RESEARCH   (United States)

^b UNIVERSITY OF SOUTH DAKOTA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

IRON; MESSENGER RNA; PROTEIN P27; RIBONUCLEASE; SMALL INTERFERING RNA;

5' UNTRANSLATED REGION; ARTICLE; CISTRON; CONTROLLED STUDY; ENZYME ASSAY; GENE CONSTRUCT; GENE INSERTION; GENETIC IDENTIFICATION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; INTERNAL RIBOSOME ENTRY SITE; PRIORITY JOURNAL; PROMOTER REGION; REPORTER GENE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSLATION INITIATION;

5' UNTRANSLATED REGIONS; ANIMALS; CELL LINE, TUMOR; CYCLIN-DEPENDENT KINASE INHIBITOR P27; HUMANS; IRON; MICE; NIH 3T3 CELLS; PEPTIDE CHAIN INITIATION, TRANSLATIONAL; PROMOTER REGIONS (GENETICS); RESPONSE ELEMENTS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA CAPS; RNA INTERFERENCE; RNA, MESSENGER; TRANSCRIPTION, GENETIC; TRANSFECTION;

EID: 34547911389     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkm512     Document Type: Article

References (25)

1. Jang,S.K., Krausslich,H.G., Nicklin,M.J., Duke,G.M., Palmenberg,A.C. and Wimmer,E. (1988) A segment of the 5′ nontranslated region of encephalomyocarditis virus RNA directs internal entry of ribosomes during in vitro translation. J. Virol., 62, 2636-2643.
2. Pelletier,J. and Sonenberg,N. (1988) Internal initiation of translation of eukaryotic mRNA directed by a sequence derived from poliovirus RNA. Nature, 334, 320-325.
3. Gradi,A., Svitkin,Y.V., Imataka,H. and Sonenberg,N. (1998) Proteolysis of human eukaryotic translation initiation factor eIF4GII, but not eIF4GI, coincides with the shutoff of host protein synthesis after poliovirus infection. Proc. Natl Acad. Sci. USA, 95, 11089-11094.
4. Stoneley,M. and Willis,A.E. (2004) Cellular internal ribosome entry segments: Structures, trans-acting factors and regulation of gene expression. Oncogene, 23, 3200-3207.
5. Kozak,M. (2001) New ways of initiating translation in eukaryotes? Mol. Cell. Biol., 21, 1899-1907.
6. Han,B. and Zhang,J.T. (2002) Regulation of gene expression by internal ribosome entry sites or cryptic promoters: The eIF4G story. Mol. Cell. Biol., 22, 7372-7384.
7. Van Eden,M.E., Byrd,M.P., Sherrill,K.W. and Lloyd,R.E. (2004) Demonstrating internal ribosome entry sites in eukaryotic mRNAs using stringent RNA test procedures. RNA, 10, 720-730.
8. Bloom,J. and Pagano,M. (2003) Deregulated degradation of the cdk inhibitor p27 and malignant transformation. Semin. in cancer biol. 13, 41-47.
9. Agrawal,D., Hauser,P., McPherson,F., Dong,F., Garcia,A. and Pledger,W.J. (1996) Repression of p27kip1 synthesis by platelet-derived growth factor in BALB/c 3T3 cells. Mol. Cell. Biol., 16, 4327-4336.
10. Hengst,L. and Reed,S.I. (1996) Translational control of p27Kip1 accumulation during the cell cycle. Science, 271, 1861-1864.
11. Millard,S.S., Yan,J.S., Nguyen,H., Pagano,M., Kiyokawa,H. and Koff,A. (1997) Enhanced ribosomal association of p27(Kip1) mRNA is a mechanism contributing to accumulation during growth arrest. J. Biol. Chem., 272, 7093-7098.
12. Miskimins,W.K., Wang,G., Hawkinson,M. and Miskimins,R. (2001) Control of cyclin-dependent kinase inhibitor p27 expression by cap-independent translation. Mol. Cell. Biol., 21, 4960-4967.
13. Cho,S., Kim,J.H., Back,S.H. and Jang,S.K. (2005) Polypyrimidine tract-binding protein enhances the internal ribosomal entry site-dependent translation of p27Kip1 mRNA and modulates transition from G1 to S phase. Mol. Cell. Biol., 25, 1283-1297.
14. Kullmann,M., Gopfert,U., Siewe,B. and Hengst,L. (2002) ELAV/Hu proteins inhibit p27 translation via an IRES element in the p27 5′UTR. Genes Dev., 16, 3087-3099.
15. Shi,Y., Sharma,A., Wu,H., Lichtenstein,A. and Gera,J. (2005) Cyclin D1 and c-myc internal ribosome entry site (IRES)-dependent translation is regulated by AKT activity and enhanced by rapamycin through a p38 MAPK- and ERK-dependent pathway. J. Biol. Chem., 280, 10964-10973.
16. Liu,Z., Dong,Z., Han,B., Yang,Y., Liu,Y. and Zhang,J.T. (2005) Regulation of expression by promoters versus internal ribosome entry site in the 5′-untranslated sequence of the human cyclin-dependent kinase inhibitor p27kip1. Nucleic Acids Res., 33, 3763-3771.
17. Jiang,H., Coleman,J., Miskimins,R. and Miskimins,W.K. (2003) Expression of constitutively active 4EBP-1 enhances p27Kip1 expression and inhibits proliferation of MCF7 breast cancer cells. Cancer Cell Int., 3 2.
18. Coleman,J., Hawkinson,M., Miskimins,R. and Miskimins,W.K. (2001) The major transcription initiation site of the p27Kip1 gene is conserved in human and mouse and produces a long 5′-UTR. BMC Mol. Biol., 2 12.
19. Annicotte,J.S., Schoonjans,K., Haby,C. and Auwerx,J. (2001) An E-box in pGL3 reporter vectors precludes their use for the study of sterol regulatory element-binding proteins. BioTechniques, 31, 993-994, 996.
20. Bert,A.G., Burrows,J., Osborne,C.S. and Cockerill,P.N. (2000) Generation of an improved luciferase reporter gene plasmid that employs a novel mechanism for high-copy replication. Plasmid, 44, 173-182.
21. Grimm,S.L. and Nordeen,S.K. (1999) Luciferase reporter gene vectors that lack potential AP-1 sites. BioTechniques, 27, 220-222.
22. Ho,C.K. and Strauss,J.F.III (2004) Activation of the control reporter plasmids pRL-TK and pRL-SV40 by multiple GATA transcription factors can lead to aberrant normalization of transfection efficiency. BMC Biotechnol., 4, 10.
23. Thirunavukkarasu,K., Miles,R.R., Halladay,D.L. and Onyia,J.E. (2000) Cryptic enhancer elements in luciferase reporter vectors respond to the osteoblast-specific transcription factor Osf2/Cbfa1. BioTechniques 28, 506-510.
24. Paguio,A., Almond,B, Fan,F, Stecha,P, Garvin,D, Wood,M and Wood,K. (2005) pGL4 vectors: A new generation of luciferase reporter vectors. Promega Notes, 89, 7-10.
25. Yoon,A., Peng,G., Brandenburger,Y., Zollo,O., Xu,W., Rego,E. and Ruggero,D. (2006) Impaired control of IRES-mediated translation in X-linked dyskeratosis congenita. Science, 312, 902-906.