A phenylbutenoid dimer, cis -3-(3′,4′-dimethoxyphenyl)-4-[(E)- 3‴,4‴-dimethoxystyryl] Cyclohex-1-ene, exhibits apoptogenic properties in T-acute lymphoblastic leukemia cells via induction of p53-independent mitochondrial signalling pathway

Evidence-based Complementary and Alternative Medicine

Volumn 2013, Issue , 2013, Pages

  Anasamy, Theebaa ^a   Abdul, Ahmad Bustamam ^a   Sukari, Mohd Aspollah ^a   Abdelwahab, Siddig Ibrahim ^b,c   Mohan, Syam ^b   Kamalidehghan, Behnam ^b   Azid, Mohd Zulkhairi ^a   Muhammad Nadzri, Nabilah ^a   Andas, A Reenaa Joys ^a   Beng, Ng Kuan ^a   Hadi, A Hamid A ^b   Sulaiman Rahman, Heshu ^a  

^a UNIVERSITY PUTRA MALAYSIA   (Malaysia)

^b UNIVERSITY OF MALAYA   (Malaysia)

^c JAZAN UNIVERSITY   (Saudi Arabia)

Author keywords

[No Author keywords available]

Indexed keywords

ANTILEUKEMIC AGENT; CASPASE 3; CASPASE 7; CASPASE 8; CASPASE 9; CIS 3 (3',4' DIMETHOXYPHENYL) 4 (3''',4''' DIMETHOXYSTYRYL)CYCLOHEX 1 ENE; CYTOCHROME C; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BID; PROTEIN P53; SECOND MITOCHONDRIAL ACTIVATOR OF CASPASE; UNCLASSIFIED DRUG; X LINKED INHIBITOR OF APOPTOSIS;

ACUTE LYMPHOBLASTIC LEUKEMIA; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BREAST ADENOCARCINOMA; BREAST CARCINOMA; CANCER CELL CULTURE; CELL CYCLE ARREST; CELL CYCLE PROGRESSION; CELL CYCLE S PHASE; CELL STRAIN HEPG2; CELL STRUCTURE; CONTROLLED STUDY; CYTOTOXICITY; DNA FRAGMENTATION; DOWN REGULATION; HELA CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; LEUKEMIA CELL; LIVER CELL CARCINOMA; MITOCHONDRIAL MEMBRANE POTENTIAL; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; QUALITATIVE ANALYSIS; RHIZOME; SIGNAL TRANSDUCTION; STRUCTURE ACTIVITY RELATION; THIN LAYER CHROMATOGRAPHY; UPREGULATION; WESTERN BLOTTING; ZINGIBER MONTANUM;

EID: 84875553771     PISSN: 1741427X     EISSN: 17414288     Source Type: Journal    
DOI: 10.1155/2013/939810     Document Type: Article

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