The Fcγ receptor expression profile on porcine dendritic cells depends on the nature of the stimulus

Veterinary Immunology and Immunopathology

Volumn 152, Issue 1-2, 2013, Pages 43-49

  Devriendt, Bert ^a   Goddeeris, Bruno M ^a,b   Cox, Eric ^a  

^a GHENT UNIVERSITY   (Belgium)

^b UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

Dendritic cells; Fc receptors; Immune complex; Pig

Indexed keywords

CD16 ANTIGEN; FC RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIGEN ANTIBODY COMPLEX; ARTICLE; CELL MATURATION; DENDRITIC CELL; IMMUNE RESPONSE; NONHUMAN;

ANIMALS; ANTIGEN-ANTIBODY COMPLEX; DENDRITIC CELLS; FIMBRIAE, BACTERIAL; LIPOPOLYSACCHARIDES; LYMPHOCYTE ACTIVATION; RECEPTORS, IGG; STATISTICS, NONPARAMETRIC; SWINE;

SUIDAE; SUS;

EID: 84875512324     PISSN: 01652427     EISSN: 18732534     Source Type: Journal    
DOI: 10.1016/j.vetimm.2012.09.021     Document Type: Article

References (29)

1. Adamova E., Walsh M.C., Gosselin D.R., Hale K., Preissler M.T., Graziano R.F., Gosselin E.J. Enhanced antigen-specific antibody and cytokine responses when targeting antigen to human FcGAMMA receptor type I using an anti-human FcGAMMA receptor type I-streptavidin fusion protein in an adjuvant-free system. Immunol. Invest. 2005, 34(4):417-429.
2. Bailey M., Stevens K., Bland P.W., Stokes C.R. A monoclonal antibody recognising an epitope associated with pig interleukin-2 receptors. J. Immunol. Methods 1992, 153:85-91.
3. Balmelli C., Vincent I.E., Rau H., Guzylack-Piriou L., McCullough K., Summerfield A. Fc gamma RII-dependent sensitisation of natural interferon-producing cells for viral infection and interferon-alpha responses. Eur. J. Immunol. 2005, 35(8):2406-2415.
4. Banchereau J., Briere F., Caux C., Davoust J., Lebecque S., Liu Y.J., Pulendran B., Palucka K. Immunobiology of dendritic cells. Annu. Rev. Immunol. 2000, 18:767-811.
5. Bitsaktsis C., Iglesias B.V., Li Y., Colino J., Snapper C.M., Hollingshead S.K., Pham G., Gosselin D.R., Gosselin E.J. Mucosal immunization with an unadjuvanted vaccine that targets Streptococcus pneumoniae PspA to human Fcγ receptor type I protects against pneumococcal infection through complement- and lactoferrin-mediated bactericidal activity. Infect. Immun. 2012, 80(3):1166-1180.
6. Boruchov A.M., Heller G., Veri M.C., Bonvini E., Ravetch J.V., Young J.W. Activating and inhibitory IgG Fc receptors on human DCs mediate opposing functions. J. Clin. Invest. 2005, 115:2914-2923.
7. Butler J.E., Wertz N., Deschacht N., Kacskovics I. Porcine IgG: structure, genetics, and evolution. Immunogenetics 2009, 61(3):209-230.
8. Caminschi I., Shortman K. Boosting antibody responses by targeting antigens to dendritic cells. Trends Immunol. 2012, 33(2):71-77.
9. Carrasco C.P., Rigden R.C., Schaffner R., Gerber H., Neuhaus V., Inumaru S., Takamatsu H., Bertoni G., McCullough K.C., Summerfield A. Porcine dendritic cells generated in vitro: morphological, phenotypic and functional properties. Immunology 2001, 104(2):175-184.
10. Devriendt B., Verdonck F., Summerfield A., Goddeeris B.M., Cox E. Targeting of Escherichia coli F4 fimbriae to Fcγ receptors enhances the maturation of porcine dendritic cells. Vet. Immunol. Immunopathol. 2010, 134:188-198.
11. Devriendt B., De Geest B.G., Cox E. Designing oral vaccines targeting intestinal dendritic cells. Expert Opin. Drug Deliv. 2011, 8(4):467-483.
12. Dhodapkar K.M., Banerjee D., Connolly J., Kukreja A., Matayeva E., Veri M.C., Ravetch J.V., Steinman R.M., Dhodapkar M.V. Selective blockade of the inhibitory Fcγ receptor (FcγRIIB) in human dendritic cells and monocytes induces a type I interferon response program. J. Exp. Med. 2007, 204(6):1359-1369.
13. Gosselin E.J., Bitsaktsis C., Li Y., Iglesias B.V. Fc receptor-targeted mucosal vaccination as a novel strategy for the generation of enhanced immunity against mucosal and non-mucosal pathogens. Arch. Immunol. Ther. Exp. 2009, 57:311-323.
14. Guermonprez P., Valladeau J., Zitvogel L., Théry C., Amigorena S. Antigen presentation and T cell stimulation by dendritic cells. Annu. Rev. Immunol. 2002, 20:621-667.
15. Inumaru S., Kokuho T., Denham S., Denyer M.S., Momotani E., Kitamura S., Corteyn A., Brookes S., Parkhouse R.M., Takamatsu H. Expression of biologically active recombinant porcine GM-CSF by baculovirus gene expression system. Immunol. Cell Biol. 1998, 76(3):195-201.
16. Lahoud M.H., Ahmet F., Kitsoulis S., Wan S.S., Vremec D., Lee C.N., Phipson B., Shi W., Smyth G.K., Lew A.M., Kato Y., Mueller S.N., Davey G.M., Heath W.R., Shortman K., Caminschi I. Targeting antigen to mouse dendritic cells via Clec9A induces potent CD4 T cell responses biased toward a follicular helper phenotype. J. Immunol. 2011, 187(2):842-850.
17. Nimmerjahn F., Bruhns P., Horiuchi K., Ravetch J.V. FcγRIV: a novel FcR with distinct IgG subclass specificity. Immunity 2005, 23:41-51.
18. Nimmerjahn F., Ravetch J.V. Fcγ receptors as regulators of immune responses. Nat. Rev. Immunol. 2008, 8:34-47.
19. Pescovitz M.D., Lunney J.K., Sachs D.H. Preparation and characterization of monoclonal antibodies reactive with porcine PBL. J. Immunol. 1984, 133:368-375.
20. Pilon C., Levast B., Meurens F., Le Vern Y., Kerboeuf D., Salmon H., Velge-Roussel F., Lebranchu Y., Baron C. CD40 engagement strongly induces CD25 expression on porcine dendritic cells and polarizes the T cell immune response toward Th1. Mol. Immunol. 2009, 46(3):437-447.
21. Ravetch J., Bolland S. IgG Fc receptors. Annu. Rev. Immunol. 2001, 19:275-290.
22. Rawool D.B., Bitsaktsis C., Li Y., Gosselin D.R., Lin Y., Kurkure N.V., Metzger D.W., Gosselin E.J. Utilization of Fc receptors as a mucosal vaccine strategy against an intracellular bacterium, Francisella tularensis. J. Immunol. 2008, 180(8):5548-5557.
23. Regnault A., Lankar D., Lacabanne V., Rodriguez A., Théry C., Rescigno M., Saito T., Verbeek S., Bonnerot C., Ricciardi-Castagnoli P., Amigorena S. Fcgamma receptor-mediated induction of dendritic cell maturation and major histocompatibility complex class I-restricted antigen presentation after immune complex internalization. J. Exp. Med. 1999, 189(2):371-380.
24. Revilla C., Poderoso T., Martínez P., Alvarez B., López-Fuertes L., Alonso F., Ezquerra A., Domínguez J. Targeting to porcine sialoadhesin receptor improves antigen presentation to T cells. Vet. Res. 2009, 40(3):14.
25. Shortman K., Lahoud M.H., Caminschi I. Improving vaccines by targeting antigens to dendritic cells. Exp. Mol. Med. 2009, 41(2):61-66.
26. Trinchieri G., Sher A. Cooperation of Toll-like receptor signals in innate immune defence. Nat. Rev. Immunol. 2007, 7:179-190.
27. Unger W.W., van Beelen A.J., Bruijns S.C., Joshi M., Fehres C.M., van Bloois L., Verstege M.I., Ambrosini M., Kalay H., Nazmi K., Bolscher J.G., Hooijberg E., de Gruijl T.D., Storm G., van Kooyk Y. Glycan-modified liposomes boost CD4+ and CD8+ T-cell responses by targeting DC-SIGN on dendritic cells. J. Control. Release 2012, 160(1):88-95. 10.1016/j.jconrel.2012.02.007.
28. Van den Broeck W., Cox E., Goddeeris B.M. Receptor-dependent immune responses in pigs after oral immunization with F4 fimbriae. Infect. Immun. 1999, 67(2):520-526.
29. Verdonck F., Joensuu J.J., Stuyven E., De Meyer J., Muilu M., Pirhonen M., Goddeeris B.M., Mast J., Niklander-Teeri V., Cox E. The polymeric stability of the Escherichia coli F4 (K88) fimbriae enhances its mucosal immunogenicity following oral immunization. Vaccine 2008, 26(45):5728-5735.