메뉴 건너뛰기




Volumn 12, Issue 3, 2013, Pages 522-532

Depletion of K-Ras promotes proteasome degradation of survivin

Author keywords

Apoptosis; Cancer; K Ras; Proteasome; Protein degradation; Survivin

Indexed keywords

BORTEZOMIB; K RAS PROTEIN; PROTEASOME; PROTEIN KINASE B; PROTEIN KINASE B BETA; RALA PROTEIN; RALB PROTEIN; SURVIVIN; THREONINE; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 1; UNCLASSIFIED DRUG;

EID: 84875505241     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.23407     Document Type: Article
Times cited : (11)

References (36)
  • 1
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: The next generation
    • PMID:21376230;
    • Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell 2011; 144: 646-74; PMID:21376230; http://dx.doi.org/10.1016/j.cell.2011.02.013
    • (2011) Cell , vol.144 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 2
    • 0036088471 scopus 로고    scopus 로고
    • IAP proteins: Blocking the road to death's door
    • PMID:12042762
    • Salvesen GS, Duckett CS. IAP proteins: blocking the road to death's door. Nat Rev Mol Cell Biol 2002; 3: 401-10; PMID:12042762; http://dx.doi.org/10. 1038/nrm830
    • (2002) Nat Rev Mol Cell Biol , vol.3 , pp. 401-410
    • Salvesen, G.S.1    Duckett, C.S.2
  • 3
    • 37549048249 scopus 로고    scopus 로고
    • The BCL-2 protein family: Opposing activities that mediate cell death
    • PMID:18097445
    • Youle RJ, Strasser A. The BCL-2 protein family: opposing activities that mediate cell death. Nat Rev Mol Cell Biol 2008; 9: 47-59; PMID:18097445; http://dx.doi.org/10.1038/nrm2308
    • (2008) Nat Rev Mol Cell Biol , vol.9 , pp. 47-59
    • Youle, R.J.1    Strasser, A.2
  • 4
    • 0032506524 scopus 로고    scopus 로고
    • Control of apoptosis and mitotic spindle checkpoint by survivin
    • PMID:9859993
    • Li F, Ambrosini G, Chu EY, Plescia J, Tognin S, Marchisio PC, et al. Control of apoptosis and mitotic spindle checkpoint by survivin. Nature 1998; 396: 580-4; PMID:9859993; http://dx.doi.org/10.1038/25141
    • (1998) Nature , vol.396 , pp. 580-584
    • Li, F.1    Ambrosini, G.2    Chu, E.Y.3    Plescia, J.4    Tognin, S.5    Marchisio, P.C.6
  • 5
    • 0035969963 scopus 로고    scopus 로고
    • An anti-apoptotic protein human survivin is a direct inhibitor of caspase-3 and -7
    • PMID:11170436
    • Shin S, Sung BJ, Cho YS, Kim HJ, Ha NC, Hwang JI, et al. An anti-apoptotic protein human survivin is a direct inhibitor of caspase-3 and -7. Biochemistry 2001; 40: 1117-23; PMID:11170436; http://dx.doi.org/10.1021/ bi001603q
    • (2001) Biochemistry , vol.40 , pp. 1117-1123
    • Shin, S.1    Sung, B.J.2    Cho, Y.S.3    Kim, H.J.4    Ha, N.C.5    Hwang, J.I.6
  • 6
    • 33750827351 scopus 로고    scopus 로고
    • The case for Survivin as mitotic regulator
    • PMID:16962308
    • Lens SM, Vader G, Medema RH. The case for Survivin as mitotic regulator. Curr Opin Cell Biol 2006; 18: 616-22; PMID:16962308; http://dx.doi.org/10.1016/ j.ceb.2006.08.016
    • (2006) Curr Opin Cell Biol , vol.18 , pp. 616-622
    • Lens, S.M.1    Vader, G.2    Medema, R.H.3
  • 7
    • 0038376119 scopus 로고    scopus 로고
    • Survivin is required for a sustained spindle checkpoint arrest in response to lack of tension
    • PMID:12805209
    • Lens SM, Wolthuis RM, Klompmaker R, Kauw J, Agami R, Brummelkamp T, et al. Survivin is required for a sustained spindle checkpoint arrest in response to lack of tension. EMBO J 2003; 22: 2934-47; PMID:12805209; http://dx.doi.org/10.1093/emboj/cdg307
    • (2003) EMBO J , vol.22 , pp. 2934-2947
    • Lens, S.M.1    Wolthuis, R.M.2    Klompmaker, R.3    Kauw, J.4    Agami, R.5    Brummelkamp, T.6
  • 8
    • 42649135123 scopus 로고    scopus 로고
    • Suppression of survivin expression by short hairpin RNA induces apoptosis in human laryngeal carcinoma cells
    • PMID:18391576
    • Chen XM, Luan XY, Lei DP, Ma XJ, Liu XX, Liu J, et al. Suppression of survivin expression by short hairpin RNA induces apoptosis in human laryngeal carcinoma cells. ORL J Otorhinolaryngol Relat Spec 2008; 70: 168-75; PMID:18391576; http://dx.doi.org/10.1159/000124290
    • (2008) ORL J Otorhinolaryngol Relat Spec , vol.70 , pp. 168-175
    • Chen, X.M.1    Luan, X.Y.2    Lei, D.P.3    Ma, X.J.4    Liu, X.X.5    Liu, J.6
  • 9
    • 50049122989 scopus 로고    scopus 로고
    • Chemically synthesized human survivin does not inhibit caspase-3
    • PMID:18539906
    • Li C, Wu Z, Liu M, Pazgier M, Lu W. Chemically synthesized human survivin does not inhibit caspase-3. Protein Sci 2008; 17: 1624-9; PMID:18539906; http://dx.doi.org/10.1110/ps.036145.108
    • (2008) Protein Sci , vol.17 , pp. 1624-1629
    • Li, C.1    Wu, Z.2    Liu, M.3    Pazgier, M.4    Lu, W.5
  • 10
    • 4544261227 scopus 로고    scopus 로고
    • An IAP-IAP complex inhibits apoptosis
    • PMID:15218035
    • Dohi T, Okada K, Xia F, Wilford CE, Samuel T, Welsh K, et al. An IAP-IAP complex inhibits apoptosis. J Biol Chem 2004; 279: 34087-90; PMID:15218035; http://dx.doi.org/10.1074/jbc.C400236200
    • (2004) J Biol Chem , vol.279 , pp. 34087-34090
    • Dohi, T.1    Okada, K.2    Xia, F.3    Wilford, C.E.4    Samuel, T.5    Welsh, K.6
  • 11
    • 0030746636 scopus 로고    scopus 로고
    • A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma
    • PMID:9256286
    • Ambrosini G, Adida C, Altieri DC. A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma. Nat Med 1997; 3: 917-21; PMID:9256286; http://dx.doi.org/10.1038/nm0897-917
    • (1997) Nat Med , vol.3 , pp. 917-921
    • Ambrosini, G.1    Adida, C.2    Altieri, D.C.3
  • 12
    • 37549036729 scopus 로고    scopus 로고
    • Survivin, cancer networks and pathwaydirected drug discovery
    • PMID:18075512
    • Altieri DC. Survivin, cancer networks and pathwaydirected drug discovery. Nat Rev Cancer 2008; 8: 61-70; PMID:18075512; http://dx.doi.org/10.1038/nrc2293
    • (2008) Nat Rev Cancer , vol.8 , pp. 61-70
    • Altieri, D.C.1
  • 13
    • 0037699432 scopus 로고    scopus 로고
    • Inhibitor of apoptosis protein (IAP) survivin is upregulated by oncogenic c-H-Ras
    • PMID:12833149
    • Sommer KW, Schamberger CJ, Schmidt GE, Sasgary S, Cerni C. Inhibitor of apoptosis protein (IAP) survivin is upregulated by oncogenic c-H-Ras. Oncogene 2003; 22: 4266-80; PMID:12833149; http://dx.doi.org/10.1038/sj.onc.1206509
    • (2003) Oncogene , vol.22 , pp. 4266-4280
    • Sommer, K.W.1    Schamberger, C.J.2    Schmidt, G.E.3    Sasgary, S.4    Cerni, C.5
  • 14
    • 34948851397 scopus 로고    scopus 로고
    • Oncogenic c-H-ras deregulates survivin expression: An improvement for survival
    • PMID:17904124
    • Sommer KW, Rodgarkia-Dara CJ, Schreiner C, Holzmann K, Krupitza G, Cerni C. Oncogenic c-H-ras deregulates survivin expression: an improvement for survival. FEBS Lett 2007; 581: 4921-6; PMID:17904124; http://dx.doi.org/10.1016/ j.febslet. 2007.09.023
    • (2007) FEBS Lett , vol.581 , pp. 4921-4926
    • Sommer, K.W.1    Rodgarkia-Dara, C.J.2    Schreiner, C.3    Holzmann, K.4    Krupitza, G.5    Cerni, C.6
  • 15
    • 4544324074 scopus 로고    scopus 로고
    • Activated H-Ras regulates hematopoietic cell survival by modulating Survivin
    • PMID:15369798
    • Fukuda S, Pelus LM. Activated H-Ras regulates hematopoietic cell survival by modulating Survivin. Biochem Biophys Res Commun 2004; 323: 636-44; PMID:15369798; http://dx.doi.org/10.1016/j.bbrc.2004.08.149
    • (2004) Biochem Biophys Res Commun , vol.323 , pp. 636-644
    • Fukuda, S.1    Pelus, L.M.2
  • 16
    • 38849209818 scopus 로고    scopus 로고
    • Survivin repression by p53, Rb and E2F2 in normal human melanocytes
    • PMID:17916908
    • Raj D, Liu T, Samadashwily G, Li F, Grossman D. Survivin repression by p53, Rb and E2F2 in normal human melanocytes. Carcinogenesis 2008; 29: 194-201; PMID:17916908; http://dx.doi.org/10.1093/carcin/bgm219
    • (2008) Carcinogenesis , vol.29 , pp. 194-201
    • Raj, D.1    Liu, T.2    Samadashwily, G.3    Li, F.4    Grossman, D.5
  • 17
    • 0034795822 scopus 로고    scopus 로고
    • Transgenic expression of survivin in keratinocytes counteracts UVB-induced apoptosis and cooperates with loss of p53
    • PMID:11581300
    • Grossman D, Kim PJ, Blanc-Brude OP, Brash DE, Tognin S, Marchisio PC, et al. Transgenic expression of survivin in keratinocytes counteracts UVB-induced apoptosis and cooperates with loss of p53. J Clin Invest 2001; 108: 991-9; PMID:11581300
    • (2001) J Clin Invest , vol.108 , pp. 991-999
    • Grossman, D.1    Kim, P.J.2    Blanc-Brude, O.P.3    Brash, D.E.4    Tognin, S.5    Marchisio, P.C.6
  • 18
    • 49649102136 scopus 로고    scopus 로고
    • Survivin expression in normal human bronchial epithelial cells: An early and critical step in tumorigenesis induced by tobacco exposure
    • PMID:18635526
    • Jin Q, Menter DG, Mao L, Hong WK, Lee HY. Survivin expression in normal human bronchial epithelial cells: an early and critical step in tumorigenesis induced by tobacco exposure. Carcinogenesis 2008; 29: 1614-22; PMID:18635526; http://dx.doi.org/10.1093/carcin/bgm234
    • (2008) Carcinogenesis , vol.29 , pp. 1614-1622
    • Jin, Q.1    Menter, D.G.2    Mao, L.3    Hong, W.K.4    Lee, H.Y.5
  • 19
    • 0030952552 scopus 로고    scopus 로고
    • Inhibition of the prenylation of K-Ras, but not H- or N-Ras, is highly resistant to CAAX peptidomimetics and requires both a farnesyltransferase and a geranylgeranyltransferase i inhibitor in human tumor cell lines
    • PMID:9315095
    • Lerner EC, Zhang TT, Knowles DB, Qian Y, Hamilton AD, Sebti SM. Inhibition of the prenylation of K-Ras, but not H- or N-Ras, is highly resistant to CAAX peptidomimetics and requires both a farnesyltransferase and a geranylgeranyltransferase I inhibitor in human tumor cell lines. Oncogene 1997; 15: 1283-8; PMID:9315095; http://dx.doi.org/10.1038/sj.onc.1201296
    • (1997) Oncogene , vol.15 , pp. 1283-1288
    • Lerner, E.C.1    Zhang, T.T.2    Knowles, D.B.3    Qian, Y.4    Hamilton, A.D.5    Sebti, S.M.6
  • 20
    • 67649394729 scopus 로고    scopus 로고
    • Discovery of a novel proteasome inhibitor selective for cancer cells over non-transformed cells
    • PMID:19471122
    • Kazi A, Lawrence H, Guida WC, McLaughlin ML, Springett GM, Berndt N, et al. Discovery of a novel proteasome inhibitor selective for cancer cells over non-transformed cells. Cell Cycle 2009; 8: 1940-51; PMID:19471122; http://dx.doi.org/10.4161/cc.8.12.8798
    • (2009) Cell Cycle , vol.8 , pp. 1940-1951
    • Kazi, A.1    Lawrence, H.2    Guida, W.C.3    McLaughlin, M.L.4    Springett, G.M.5    Berndt, N.6
  • 21
    • 36048968159 scopus 로고    scopus 로고
    • Geranylgeranyltransferase i inhibitors target RalB to inhibit anchorage-dependent growth and induce apoptosis and RalA to inhibit anchorageindependent growth
    • PMID:17875936
    • Falsetti SC, Wang DA, Peng H, Carrico D, Cox AD, Der CJ, et al. Geranylgeranyltransferase I inhibitors target RalB to inhibit anchorage-dependent growth and induce apoptosis and RalA to inhibit anchorageindependent growth. Mol Cell Biol 2007; 27: 8003-14; PMID:17875936; http://dx.doi.org/10.1128/MCB.00057-07
    • (2007) Mol Cell Biol , vol.27 , pp. 8003-8014
    • Falsetti, S.C.1    Wang, D.A.2    Peng, H.3    Carrico, D.4    Cox, A.D.5    Der, C.J.6
  • 22
    • 0034700154 scopus 로고    scopus 로고
    • Regulation of apoptosis at cell division by p34cdc2 phosphorylation of survivin
    • PMID:11069302
    • O'Connor DS, Grossman D, Plescia J, Li F, Zhang H, Villa A, et al. Regulation of apoptosis at cell division by p34cdc2 phosphorylation of survivin. Proc Natl Acad Sci U S A 2000; 97: 13103-7; PMID:11069302; http://dx.doi.org/ 10.1073/pnas.240390697
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 13103-13107
    • O'Connor, D.S.1    Grossman, D.2    Plescia, J.3    Li, F.4    Zhang, H.5    Villa, A.6
  • 23
    • 0037228959 scopus 로고    scopus 로고
    • Suppression of survivin phosphorylation on Thr34 by flavopiridol enhances tumor cell apoptosis
    • PMID:12517802
    • Wall NR, O'Connor DS, Plescia J, Pommier Y, Altieri DC. Suppression of survivin phosphorylation on Thr34 by flavopiridol enhances tumor cell apoptosis. Cancer Res 2003; 63: 230-5; PMID:12517802
    • (2003) Cancer Res , vol.63 , pp. 230-235
    • Wall, N.R.1    O'Connor, D.S.2    Plescia, J.3    Pommier, Y.4    Altieri, D.C.5
  • 25
    • 81255201334 scopus 로고    scopus 로고
    • β-catenin and K-RAS synergize to form primitive renal epithelial tumors with features of epithelial Wilms' tumors
    • PMID:21983638;
    • Clark PE, Polosukhina D, Love H, Correa H, Coffin C, Perlman EJ, et al. β-Catenin and K-RAS synergize to form primitive renal epithelial tumors with features of epithelial Wilms' tumors. Am J Pathol 2011; 179: 3045-55; PMID:21983638; http://dx.doi.org/10.1016/j.ajpath.2011.08.006
    • (2011) Am J Pathol , vol.179 , pp. 3045-3055
    • Clark, P.E.1    Polosukhina, D.2    Love, H.3    Correa, H.4    Coffin, C.5    Perlman, E.J.6
  • 26
    • 0034532701 scopus 로고    scopus 로고
    • The ubiquitin-proteasome pathway regulates survivin degradation in a cell cycle-dependent manner
    • PMID:11069780
    • Zhao J, Tenev T, Martins LM, Downward J, Lemoine NR. The ubiquitin-proteasome pathway regulates survivin degradation in a cell cycle-dependent manner. J Cell Sci 2000; 113: 4363-71; PMID:11069780
    • (2000) J Cell Sci , vol.113 , pp. 4363-4371
    • Zhao, J.1    Tenev, T.2    Martins, L.M.3    Downward, J.4    Lemoine, N.R.5
  • 27
    • 0037102561 scopus 로고    scopus 로고
    • Distinct requirements for Ras oncogenesis in human versus mouse cells
    • PMID:12183360
    • Hamad NM, Elconin JH, Karnoub AE, Bai W, Rich JN, Abraham RT, et al. Distinct requirements for Ras oncogenesis in human versus mouse cells. Genes Dev 2002; 16: 2045-57; PMID:12183360; http://dx.doi.org/10.1101/gad.993902
    • (2002) Genes Dev , vol.16 , pp. 2045-2057
    • Hamad, N.M.1    Elconin, J.H.2    Karnoub, A.E.3    Bai, W.4    Rich, J.N.5    Abraham, R.T.6
  • 28
    • 0027170451 scopus 로고
    • Mitogen-activated protein kinases p42mapk and p44mapk are required for fibroblast proliferation
    • PMID:8397401
    • Pagès G, Lenormand P, L'Allemain G, Chambard JC, Meloche S, Pouysségur j.Mitogen-activated protein kinases p42mapk and p44mapk are required for fibroblast proliferation. Proc Natl Acad Sci U S A 1993; 90: 8319-23; PMID:8397401; http://dx.doi.org/10.1073/pnas.90.18.8319
    • (1993) Proc Natl Acad Sci U S A , vol.90 , pp. 8319-8323
    • Pagès, G.1    Lenormand, P.2    L'Allemain, G.3    Chambard, J.C.4    Meloche, S.5    Pouysségur, J.6
  • 29
    • 0028096233 scopus 로고
    • The 3Rs of life: Ras, Raf and growth regulation
    • PMID:8191584
    • Moodie SA, Wolfman A. The 3Rs of life: Ras, Raf and growth regulation. Trends Genet 1994; 10: 44-8; PMID:8191584; http://dx.doi.org/10.1016/0168- 9525(94)90147-3
    • (1994) Trends Genet , vol.10 , pp. 44-48
    • Moodie, S.A.1    Wolfman, A.2
  • 30
    • 33748063941 scopus 로고    scopus 로고
    • Roles of the RAF/MEK/ERK and PI3K/PTEN/AKT pathways in malignant transformation and drug resistance
    • PMID:16854453
    • McCubrey JA, Steelman LS, Abrams SL, Lee JT, Chang F, Bertrand FE, et al. Roles of the RAF/MEK/ERK and PI3K/PTEN/AKT pathways in malignant transformation and drug resistance. Adv Enzyme Regul 2006; 46: 249-79; PMID:16854453; http://dx.doi.org/10.1016/j.advenzreg.2006.01.004
    • (2006) Adv Enzyme Regul , vol.46 , pp. 249-279
    • McCubrey, J.A.1    Steelman, L.S.2    Abrams, S.L.3    Lee, J.T.4    Chang, F.5    Bertrand, F.E.6
  • 31
    • 77949568748 scopus 로고    scopus 로고
    • Genetic analysis of Ras signalling pathways in cell proliferation, migration and survival
    • PMID:20150892;
    • Drosten M, Dhawahir A, Sum EY, Urosevic J, Lechuga CG, Esteban LM, et al. Genetic analysis of Ras signalling pathways in cell proliferation, migration and survival. EMBO J 2010; 29: 1091-104; PMID:20150892; http://dx.doi.org/10. 1038/emboj.2010.7
    • (2010) EMBO J , vol.29 , pp. 1091-1104
    • Drosten, M.1    Dhawahir, A.2    Sum, E.Y.3    Urosevic, J.4    Lechuga, C.G.5    Esteban, L.M.6
  • 32
    • 66249116702 scopus 로고    scopus 로고
    • PI3K pathway activation mediates resistance to MEK inhibitors in KRAS mutant cancers
    • PMID:19401449
    • Wee S, Jagani Z, Xiang KX, Loo A, Dorsch M, Yao YM, et al. PI3K pathway activation mediates resistance to MEK inhibitors in KRAS mutant cancers. Cancer Res 2009; 69: 4286-93; PMID:19401449; http://dx.doi.org/10.1158/0008-5472.CAN- 08-4765
    • (2009) Cancer Res , vol.69 , pp. 4286-4293
    • Wee, S.1    Jagani, Z.2    Xiang, K.X.3    Loo, A.4    Dorsch, M.5    Yao, Y.M.6
  • 33
    • 70449091786 scopus 로고    scopus 로고
    • Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1
    • PMID:19847166
    • Barbie DA, Tamayo P, Boehm JS, Kim SY, Moody SE, Dunn IF, et al. Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1. Nature 2009; 462: 108-12; PMID:19847166; http://dx.doi.org/10.1038/ nature08460
    • (2009) Nature , vol.462 , pp. 108-112
    • Barbie, D.A.1    Tamayo, P.2    Boehm, J.S.3    Kim, S.Y.4    Moody, S.E.5    Dunn, I.F.6
  • 34
    • 65649108558 scopus 로고    scopus 로고
    • A Gene Expression Signature Associated with "k-Ras addiction" reveals regulators of EMT and tumor cell survival
    • PMID:19477428
    • Singh A, Greninger P, Rhodes D, Koopman L, Violette S, Bardeesy N, et al. A gene expression signature associated with "K-Ras addiction" reveals regulators of EMT and tumor cell survival. Cancer Cell 2009; 15: 489-500; PMID:19477428; http://dx.doi.org/10.1016/j.ccr.2009.03.022
    • (2009) Cancer Cell , vol.15 , pp. 489-500
    • Singh, A.1    Greninger, P.2    Rhodes, D.3    Koopman, L.4    Violette, S.5    Bardeesy, N.6
  • 35
    • 33846846261 scopus 로고    scopus 로고
    • Survivin depletion preferentially reduces the survival of activated K-Rastransformed cells
    • PMID:17237286
    • Sarthy AV, Morgan-Lappe SE, Zakula D, Vernetti L, Schurdak M, Packer JC, et al. Survivin depletion preferentially reduces the survival of activated K-Rastransformed cells. Mol Cancer Ther 2007; 6: 269-76; PMID:17237286; http://dx.doi.org/10.1158/1535-7163.MCT-06-0560
    • (2007) Mol Cancer Ther , vol.6 , pp. 269-276
    • Sarthy, A.V.1    Morgan-Lappe, S.E.2    Zakula, D.3    Vernetti, L.4    Schurdak, M.5    Packer, J.C.6
  • 36
    • 34347231636 scopus 로고    scopus 로고
    • Melanocyte expression of survivin promotes development and metastasis of UV-induced melanoma in HGF-transgenic mice
    • PMID:17545596
    • Thomas J, Liu T, Cotter MA, Florell SR, Robinette K, Hanks AN, et al. Melanocyte expression of survivin promotes development and metastasis of UV-induced melanoma in HGF-transgenic mice. Cancer Res 2007; 67: 5172-8; PMID:17545596; http://dx.doi.org/10.1158/0008-5472.CAN-06-3669
    • (2007) Cancer Res , vol.67 , pp. 5172-5178
    • Thomas, J.1    Liu, T.2    Cotter, M.A.3    Florell, S.R.4    Robinette, K.5    Hanks, A.N.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.