-
1
-
-
42349104331
-
Qinghaosu (artemisinin): The price of success
-
White NJ (2008) Qinghaosu (artemisinin): The price of success. Science 320(5874): 330-334.
-
(2008)
Science
, vol.320
, Issue.5874
, pp. 330-334
-
-
White, N.J.1
-
2
-
-
77952376553
-
Malaria's drug miracle in danger
-
Enserink M (2010) Malaria's drug miracle in danger. Science 328(5980):844-846.
-
(2010)
Science
, vol.328
, Issue.5980
, pp. 844-846
-
-
Enserink, M.1
-
3
-
-
68049123592
-
Artemisinin resistance in Plasmodium falciparum malaria
-
Dondorp AM, et al. (2009) Artemisinin resistance in Plasmodium falciparum malaria. N Engl J Med 361(5):455-467.
-
(2009)
N Engl J Med
, vol.361
, Issue.5
, pp. 455-467
-
-
Dondorp, A.M.1
-
4
-
-
84861461519
-
Emergence of artemisinin-resistant malaria on the western border of Thailand: A longitudinal study
-
Phyo AP, et al. (2012) Emergence of artemisinin-resistant malaria on the western border of Thailand: A longitudinal study. Lancet 379(9830):1960-1966.
-
(2012)
Lancet
, vol.379
, Issue.9830
, pp. 1960-1966
-
-
Phyo, A.P.1
-
5
-
-
79960992639
-
Artemisinin activity against Plasmodium falciparum requires hemoglobin uptake and digestion
-
Klonis N, et al. (2011) Artemisinin activity against Plasmodium falciparum requires hemoglobin uptake and digestion. Proc Natl Acad Sci USA 108(28):11405-11410.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, Issue.28
, pp. 11405-11410
-
-
Klonis, N.1
-
6
-
-
76649123110
-
Digestive-vacuole genesis and endocytic processes in the early intraerythrocytic stages of Plasmodium falciparum
-
Abu Bakar NA, Klonis N, Hanssen E, Chan C, Tilley L (2010) Digestive-vacuole genesis and endocytic processes in the early intraerythrocytic stages of Plasmodium falciparum. J Cell Sci 123(Pt 3):441-450.
-
(2010)
J Cell Sci
, vol.123
, Issue.PART 3
, pp. 441-450
-
-
Abu Bakar, N.A.1
Klonis, N.2
Hanssen, E.3
Chan, C.4
Tilley, L.5
-
7
-
-
78651077288
-
Intrahost modeling of artemisinin resistance in Plasmodium falciparum
-
Saralamba S, et al. (2011) Intrahost modeling of artemisinin resistance in Plasmodium falciparum. Proc Natl Acad Sci USA 108(1):397-402.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, Issue.1
, pp. 397-402
-
-
Saralamba, S.1
-
8
-
-
0027280310
-
Plasmodium falciparum: In vitro studies of the pharmacodynamic properties of drugs used for the treatment of severe malaria
-
ter Kuile F, White NJ, Holloway P, Pasvol G, Krishna S (1993) Plasmodium falciparum: In vitro studies of the pharmacodynamic properties of drugs used for the treatment of severe malaria. Exp Parasitol 76(1):85-95.
-
(1993)
Exp Parasitol
, vol.76
, Issue.1
, pp. 85-95
-
-
Ter Kuile, F.1
White, N.J.2
Holloway, P.3
Pasvol, G.4
Krishna, S.5
-
9
-
-
34247126868
-
Trioxaquines are new antimalarial agents active on all erythrocytic forms, including gametocytes
-
Benoit-Vical F, et al. (2007) Trioxaquines are new antimalarial agents active on all erythrocytic forms, including gametocytes. Antimicrob Agents Chemother 51(4): 1463-1472.
-
(2007)
Antimicrob Agents Chemother
, vol.51
, Issue.4
, pp. 1463-1472
-
-
Benoit-Vical, F.1
-
10
-
-
0030152851
-
Vitro stage-specific sensitivity of Plasmodium falciparum to quinine and artemisinin drugs
-
Skinner TS, Manning LS, Johnston WA, Davis TM (1996) In vitro stage-specific sensitivity of Plasmodium falciparum to quinine and artemisinin drugs. Int J Parasitol 26(5):519-525.
-
(1996)
Int J Parasitol
, vol.26
, Issue.5
, pp. 519-525
-
-
Skinner, T.S.1
Manning, L.S.2
Johnston, W.A.3
Davis, T.M.4
-
11
-
-
38149059991
-
Clinical pharmacology of artemisinin-based combination therapies
-
German PI, Aweeka FT (2008) Clinical pharmacology of artemisinin-based combination therapies. Clin Pharmacokinet 47(2):91-102.
-
(2008)
Clin Pharmacokinet
, vol.47
, Issue.2
, pp. 91-102
-
-
German, P.I.1
Aweeka, F.T.2
-
12
-
-
70449732094
-
Artemisinin-based combination therapies: A vital tool in efforts to eliminate malaria
-
Eastman RT, Fidock DA (2009) Artemisinin-based combination therapies: A vital tool in efforts to eliminate malaria. Nat Rev Microbiol 7(12):864-874.
-
(2009)
Nat Rev Microbiol
, vol.7
, Issue.12
, pp. 864-874
-
-
Eastman, R.T.1
Fidock, D.A.2
-
13
-
-
19344377032
-
Contribution of the pfmdr1 gene to antimalarial drug-resistance
-
Duraisingh MT, Cowman AF (2005) Contribution of the pfmdr1 gene to antimalarial drug-resistance. Acta Trop 94(3):181-190.
-
(2005)
Acta Trop
, vol.94
, Issue.3
, pp. 181-190
-
-
Duraisingh, M.T.1
Cowman, A.F.2
-
14
-
-
0034708162
-
Pgh1 modulates sensitivity and resistance to multiple antimalarials in Plasmodium falciparum
-
Reed MB, Saliba KJ, Caruana SR, Kirk K, Cowman AF (2000) Pgh1 modulates sensitivity and resistance to multiple antimalarials in Plasmodium falciparum. Nature 403(6772): 906-909.
-
(2000)
Nature
, vol.403
, Issue.6772
, pp. 906-909
-
-
Reed, M.B.1
Saliba, K.J.2
Caruana, S.R.3
Kirk, K.4
Cowman, A.F.5
-
15
-
-
84867087846
-
Mechanisms of in vitro resistance to dihydroartemisinin in Plasmodium falciparum
-
Cui L, et al. (2012) Mechanisms of in vitro resistance to dihydroartemisinin in Plasmodium falciparum. Mol Microbiol 86(1):111-128.
-
(2012)
Mol Microbiol
, vol.86
, Issue.1
, pp. 111-128
-
-
Cui, L.1
-
16
-
-
0034112601
-
Increased sensitivity to the antimalarials mefloquine and artemisinin is conferred by mutations in the pfmdr1 gene of Plasmodium falciparum
-
Duraisingh MT, Roper C, Walliker D, Warhurst DC (2000) Increased sensitivity to the antimalarials mefloquine and artemisinin is conferred by mutations in the pfmdr1 gene of Plasmodium falciparum. Mol Microbiol 36(4):955-961.
-
(2000)
Mol Microbiol
, vol.36
, Issue.4
, pp. 955-961
-
-
Duraisingh, M.T.1
Roper, C.2
Walliker, D.3
Warhurst, D.C.4
-
17
-
-
79952732772
-
Synthetic ozonide drug candidate OZ439 offers new hope for a single-dose cure of uncomplicated malaria
-
Charman SA, et al. (2011) Synthetic ozonide drug candidate OZ439 offers new hope for a single-dose cure of uncomplicated malaria. Proc Natl Acad Sci USA 108(11):4400-4405.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, Issue.11
, pp. 4400-4405
-
-
Charman, S.A.1
-
18
-
-
79957493743
-
Plasmodium falciparum resistance to cytocidal versus cytostatic effects of chloroquine
-
Paguio MF, Bogle KL, Roepe PD (2011) Plasmodium falciparum resistance to cytocidal versus cytostatic effects of chloroquine. Mol Biochem Parasitol 178(1-2):1-6.
-
(2011)
Mol Biochem Parasitol
, vol.178
, Issue.1-2
, pp. 1-6
-
-
Paguio, M.F.1
Bogle, K.L.2
Roepe, P.D.3
-
19
-
-
0030007219
-
Pharmacokinetics of quinine, chloroquine and amodiaquine. Clinical implications
-
Krishna S, White NJ (1996) Pharmacokinetics of quinine, chloroquine and amodiaquine. Clinical implications. Clin Pharmacokinet 30(4):263-299.
-
(1996)
Clin Pharmacokinet
, vol.30
, Issue.4
, pp. 263-299
-
-
Krishna, S.1
White, N.J.2
-
20
-
-
0024546853
-
Stage specific actions of antimalarial drugs on Plasmodium falciparum in culture
-
Geary TG, Divo AA, Jensen JB (1989) Stage specific actions of antimalarial drugs on Plasmodium falciparum in culture. Am J Trop Med Hyg 40(3):240-244.
-
(1989)
Am J Trop Med Hyg
, vol.40
, Issue.3
, pp. 240-244
-
-
Geary, T.G.1
Divo, A.A.2
Jensen, J.B.3
-
21
-
-
0029894037
-
Artemisinin and the antimalarial endoperoxides: From herbal remedy to targeted chemotherapy
-
Meshnick SR, Taylor TE, Kamchonwongpaisan S (1996) Artemisinin and the antimalarial endoperoxides: From herbal remedy to targeted chemotherapy. Microbiol Rev 60(2):301-315.
-
(1996)
Microbiol Rev
, vol.60
, Issue.2
, pp. 301-315
-
-
Meshnick, S.R.1
Taylor, T.E.2
Kamchonwongpaisan, S.3
-
22
-
-
84872009554
-
Mechanism-based model of parasite growth and dihydroartemisinin pharmacodynamics in murine malaria
-
Patel K, et al. (2013) Mechanism-based model of parasite growth and dihydroartemisinin pharmacodynamics in murine malaria. Antimicrob Agents Chemother 57(1):508-516.
-
(2013)
Antimicrob Agents Chemother
, vol.57
, Issue.1
, pp. 508-516
-
-
Patel, K.1
-
23
-
-
84455161818
-
Phenotypic and genotypic analysis of in vitro-selected artemisinin-resistant progeny of Plasmodium falciparum
-
Tucker MS, Mutka T, Sparks K, Patel J, Kyle DE (2012) Phenotypic and genotypic analysis of in vitro-selected artemisinin-resistant progeny of Plasmodium falciparum. Antimicrob Agents Chemother 56(1):302-314.
-
(2012)
Antimicrob Agents Chemother
, vol.56
, Issue.1
, pp. 302-314
-
-
Tucker, M.S.1
Mutka, T.2
Sparks, K.3
Patel, J.4
Kyle, D.E.5
-
24
-
-
77958086412
-
Artemisinin-induced dormancy in plasmodium falciparum: Duration, recovery rates, and implications in treatment failure
-
Teuscher F, et al. (2010) Artemisinin-induced dormancy in plasmodium falciparum: Duration, recovery rates, and implications in treatment failure. J Infect Dis 202(9): 1362-1368.
-
(2010)
J Infect Dis
, vol.202
, Issue.9
, pp. 1362-1368
-
-
Teuscher, F.1
-
25
-
-
77951220629
-
Increased tolerance to artemisinin in Plasmodium falciparum is mediated by a quiescence mechanism
-
Witkowski B, et al. (2010) Increased tolerance to artemisinin in Plasmodium falciparum is mediated by a quiescence mechanism. Antimicrob Agents Chemother 54(5):1872-1877.
-
(2010)
Antimicrob Agents Chemother
, vol.54
, Issue.5
, pp. 1872-1877
-
-
Witkowski, B.1
-
26
-
-
84863895349
-
Vitro-reduced susceptibility to artemether in P. falciparum and its association with polymorphisms on transporter genes
-
Bustamante C, et al. (2012) In vitro-reduced susceptibility to artemether in P. falciparum and its association with polymorphisms on transporter genes. J Infect Dis 206(3):324-332.
-
(2012)
J Infect Dis
, vol.206
, Issue.3
, pp. 324-332
-
-
Bustamante, C.1
-
27
-
-
80054973132
-
Recent clinical and molecular insights into emerging artemisinin resistance in Plasmodium falciparum
-
O'Brien C, Henrich PP, Passi N, Fidock DA (2011) Recent clinical and molecular insights into emerging artemisinin resistance in Plasmodium falciparum. Curr Opin Infect Dis 24(6):570-577.
-
(2011)
Curr Opin Infect Dis
, vol.24
, Issue.6
, pp. 570-577
-
-
O'Brien, C.1
Henrich, P.P.2
Passi, N.3
Fidock, D.A.4
-
28
-
-
79961008996
-
Artemisinin resistance in Plasmodium falciparum is associated with an altered temporal pattern of transcription
-
Mok S, et al. (2011) Artemisinin resistance in Plasmodium falciparum is associated with an altered temporal pattern of transcription. BMC Genomics 12:391.
-
(2011)
BMC Genomics
, vol.12
, pp. 391
-
-
Mok, S.1
-
29
-
-
84859506329
-
A major genome region underlying artemisinin resistance in malaria
-
Cheeseman IH, et al. (2012) A major genome region underlying artemisinin resistance in malaria. Science 336(6077):79-82.
-
(2012)
Science
, vol.336
, Issue.6077
, pp. 79-82
-
-
Cheeseman, I.H.1
-
30
-
-
77952664258
-
Role of pfmdr1 amplification and expression in induction of resistance to artemisinin derivatives in Plasmodium falciparum
-
Chavchich M, et al. (2010) Role of pfmdr1 amplification and expression in induction of resistance to artemisinin derivatives in Plasmodium falciparum. Antimicrob Agents Chemother 54(6):2455-2464.
-
(2010)
Antimicrob Agents Chemother
, vol.54
, Issue.6
, pp. 2455-2464
-
-
Chavchich, M.1
-
31
-
-
77649113101
-
Dual labeling with a far red probe permits analysis of growth and oxidative stress in P. falciparum-infected erythrocytes
-
Fu Y, Tilley L, Kenny S, Klonis N (2010) Dual labeling with a far red probe permits analysis of growth and oxidative stress in P. falciparum-infected erythrocytes. Cytometry A 77(3):253-263.
-
(2010)
Cytometry A
, vol.77
, Issue.3
, pp. 253-263
-
-
Fu, Y.1
Tilley, L.2
Kenny, S.3
Klonis, N.4
-
34
-
-
84872858923
-
Reduced artemisinin susceptibility of Plasmodium falciparum ring stages in western Cambodia
-
Witkowski B, et al. (2013) Reduced artemisinin susceptibility of Plasmodium falciparum ring stages in western Cambodia. Antimicrob Agents Chemother 57(2):914-923.
-
(2013)
Antimicrob Agents Chemother
, vol.57
, Issue.2
, pp. 914-923
-
-
Witkowski, B.1
|