Vascular endothelial growth factor-D expression is an independent prognostic marker for survival in colorectal carcinoma

Cancer Research

Volumn 62, Issue 6, 2002, Pages 1669-1675

  White, Jeff D ^a   Hewett, Peter W ^a   Kosuge, Dennis ^a   McCulloch, Thomas ^b   Enholm, Berndt C ^c   Carmichael, James ^a   Murray, J Clifford ^a  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^b NOTTINGHAM CITY HOSPITAL   (United Kingdom)

^c UNIVERSITY OF HELSINKI   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

VASCULOTROPIN; VASCULOTROPIN RECEPTOR;

ADULT; AGED; ARTICLE; CANCER SURVIVAL; COLORECTAL CARCINOMA; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION;

ADENOMA; AGED; COLORECTAL NEOPLASMS; ENDOTHELIAL GROWTH FACTORS; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; INTESTINAL MUCOSA; MALE; NEOVASCULARIZATION, PATHOLOGIC; PRECANCEROUS CONDITIONS; PROGNOSIS; RECEPTOR PROTEIN-TYROSINE KINASES; RECEPTORS, GROWTH FACTOR; TUMOR MARKERS, BIOLOGICAL; VASCULAR ENDOTHELIAL GROWTH FACTOR D; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-3;

EID: 0037086278     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (44)

1. Regulation of angiogenesis via vascular endothelial growth factor receptors
2. Vascular endothelial growth factor-D (VEGF-D) is a ligand for the tyrosine kinases VEGF receptor 2 (Flk-1) and VEGF receptor 3 (Flt-4)
3. C-fos-induced growth factor/vascular endothelial growth factor-D induces angiogenesis in vivo and in vitro
4. Restricted expression pattern of VEGF-D in the adult and fetal mouse: High expression in the embryonic lung
5. VEGF-D promotes the metastatic spread of tumor cells via the lymphatics
6. VEGF-C and VEGF-D expression in neuroendocrine cells and their receptor, VEGFR-3, in fenestrated blood vessels in human tissues
7. Identification of a c-fos-induced gene that is related to the platelet-derived growth factor/vascular endothelial growth factor family
8. Localization of vascular endothelial growth factor-D in malignant melanoma suggests a role in tumor angiogenesis
9. Expression of vascular endothelial growth factor (VEGF) family members in breast cancer
10. Expression of vascular endothelial growth factors A, B, C, and D and their relationships to lymph node status in lung adenocarcinoma
11. The specificity of receptor binding by vascular endothelial growth factor-D is different in mouse and man
12. Cardiovascular failure in mouse embryos deficient VEGF receptor-3
13. Involvement of the vascular endothelial growth factor receptor-3 in maintenance of integrity of endothelial cell lining during tumor angiogenesis
14. VEGFR-3 and its ligand VEGF-C are associated with angiogenesis in breast cancer
15. Lack of lymphatic vascular specificity of vascular endothelial growth factor receptor 3 in 185 vascular tumors
16. Expression of vascular endothelial growth factor receptor 3 in blood and lymphatic vessels of lung adenocarcinoma
17. Prospective study of intratumoral microvessel density, p53 expression and survival in colorectal cancer
18. Tumor angiogenesis in stage II colorectal carcinoma: Association with survival
19. Prognostic significance of the microvessel count in colorectal cancer
20. p53, vessel count, and vascular endothelial growth factor expression in human colon cancer
21. Combined analysis of p53 and vascular endothelial growth factor expression in colorectal carcinoma for determination of tumor vascularity and liver metastasis
22. Prognostic factors in colorectal cancer. Literature review for clinical application
23. Tumor angiogenesis: Review of current applications in tumor prognostication
24. Method for the quantitative morphological analysis of tissues
25. Tumoral vascularity as a prognostic factor in cancer
26. Lack of lymphangiogenesis in human primary cutaneous melanoma. Consequences for the mechanism of lymphatic dissemination
27. Prognosis of breast-carcinoma lymphagenesis evaluated by immunohistochemical investigation of vascular-endothelial-growth-factor receptor 3
28. Expression of the vascular endothelial growth factor receptor VEGFR-3 in lymphatic endothelium of the skin and in vascular tumors
29. Lymphatic endothelium and Kaposi's sarcoma spindle cells detected by antibodies against the vascular endothelial growth factor receptor-3
30. LYVE-1, a new homologue of the CD44 glycoprotein, is a lymph-specific receptor for hyaluronan
31. VEGF and VEGF type C play an important role in angiogenesis and lymphangiogenesis in human malignant mesothelioma tumors
32. Role of vascular endothelial growth factor C expression in the development of lymph node metastasis in gastric cancer
33. Immunohistochemical study of tumor angiogenesis in oral squamous cell carcinoma
34. Angiogenesis in colorectal tumors: Microvessel quantitation in adenomas and carcinomas with clinicopathological correlations
35. Heterogeneity of vascular endothelial cells with relevance to diagnosis of vascular tumors
36. Vascular endothelial growth factor receptor-3 in lymphangiogenesis in wound healing
37. Lymphocytic infiltration and survival in rectal cancer
38. Platelet-derived endothelial growth factor in human colon cancer angiogenesis: Role of infiltrating cells
39. Necrosis correlates with high vascular density and focal macrophage infiltration in invasive carcinoma of the breast
40. Significance of tumor-associated macrophages, vascular endothelial growth factor and thrombospondin-1 expression for tumor angiogenesis and prognosis in endometrial carcinomas
41. Angiogenesis extent and macrophage density increase simultaneously with pathological progression in B-cell non-Hodgkin's lymphoma
42. Proinflammatory mediators stimulate neutrophil-directed angiogenesis
43. Regulation of vascular endothelial growth factor expression in human colon cancer by interleukin-1β
44. Pro-inflammatory cytokines regulate expression of the lymphatic endothelial mitogen vascular endothelial growth factor-C