Chemical and enzymatic site specific pegylation of hGH

Bioconjugate Chemistry

Volumn 24, Issue 3, 2013, Pages 456-463

  Da Silva Freitas, Débora ^a   Mero, Anna ^b   Pasut, Gianfranco ^b  

^a Fellow of the National Research Council   (Brazil)

^b UNIVERSITY OF PADOVA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMICAL BONDS; DICHROISM; MASS SPECTROMETRY; PROTEINS;

CONJUGATED PROTEINS; COVALENT ATTACHMENT; HALF LIVES; HUMAN GROWTH HORMONE; MICROBIAL TRANSGLUTAMINASE; N-TERMINALS; PEGYLATED; PEGYLATION; PHARMACEUTICAL PROTEIN; SITE-SPECIFIC;

POLYETHYLENE GLYCOLS;

ALCOHOL; ALDEHYDE; GLYCINE; HUMAN GROWTH HORMONE; MACROGOL; PROTEIN GLUTAMINE GAMMA GLUTAMYLTRANSFERASE; WATER;

AMINO TERMINAL SEQUENCE; ANIMAL EXPERIMENT; ARTICLE; CHEMICAL MODIFICATION; CIRCULAR DICHROISM; CONTROLLED STUDY; COVALENT BOND; DRUG BLOOD LEVEL; DRUG HALF LIFE; DRUG STRUCTURE; ENZYME ACTIVITY; FEMALE; GROWTH HORMONE BLOOD LEVEL; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MOLECULAR WEIGHT; NONHUMAN; PEGYLATION; PROTEIN SECONDARY STRUCTURE; RAT;

RATTUS;

EID: 84875415951     PISSN: 10431802     EISSN: 15204812     Source Type: Journal    
DOI: 10.1021/bc300594y     Document Type: Article

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