Structures and comparative characterization of biosynthetic gene clusters for cyanosporasides, enediyne-derived natural products from marine actinomycetes

Journal of the American Chemical Society

Volumn 135, Issue 11, 2013, Pages 4171-4174

  Lane, Amy L ^a,c   Nam, Sang Jip ^a,d   Fukuda, Takashi ^a,e   Yamanaka, Kazuya ^a   Kauffman, Christopher A ^a   Jensen, Paul R ^a   Fenical, William ^a,b   Moore, Bradley S ^a,b  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF NORTH FLORIDA   (United States)

^d Ewha Womans University   (South Korea)

^e KITASATO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BIOSYNTHETIC GENE CLUSTER; COMPARATIVE CHARACTERIZATIONS; FUNCTIONALIZATIONS; ISOLATION AND CHARACTERIZATION; MARINE ACTINOMYCETE; NATURAL PRODUCTS; STREPTOMYCES SP; STRUCTURAL DIVERSITY;

BACTERIA; BIOSYNTHESIS; CYANIDES; GENETIC ENGINEERING; KETONES;

ORGANIC COMPOUNDS;

ENEDIYNE; NATURAL PRODUCT;

ARTICLE; BIOSYNTHESIS; CHEMICAL ANALYSIS; CONTROLLED STUDY; GENE CLUSTER; GENE SEQUENCE; MARINE BACTERIUM; MOLECULAR CLONING; MUTAGENESIS; NONHUMAN; SALINISPORA PACIFICA; STREPTOMYCES;

ACTINOBACTERIA; BIOLOGICAL AGENTS; ENEDIYNES; GENES, BACTERIAL; GLYCOSIDES; INDENES; MULTIGENE FAMILY; STREPTOMYCES;

EID: 84875408810     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja311065v     Document Type: Article

References (22)

1. Liang, Z. X. Nat. Prod. Rep. 2010, 27, 499
2. Jean, M.; Tomasi, S.; van de Weghe, P. Org. Biomol. Chem. 2012, 10, 7453
3. Zazopoulos, E.; Huang, K. X.; Staffa, A.; Liu, W.; Bachmann, B. O.; Nonaka, K.; Ahlert, J.; Thorson, J. S.; Shen, B.; Farnet, C. M. Nat. Biotechnol. 2003, 21, 187
4. Liu, W.; Ahlert, J.; Gao, Q. J.; Wendt-Pienkowski, E.; Shen, B.; Thorson, J. S. Proc. Natl. Acad. Sci. U.S.A. 2003, 100, 11959
5. Buchanan, G. O.; Williams, P. G.; Feling, R. H.; Kauffman, C. A.; Jensen, P. R.; Fenical, W. Org. Lett. 2005, 7, 2731
6. Oh, D. C.; Williams, P. G.; Kauffman, C. A.; Jensen, P. R.; Fenical, W. Org. Lett. 2006, 8, 1021
7. Nam, S.-J.; Gaudencio, S. P.; Kauffman, C. A.; Jensen, P. R.; Kondratyuk, T. P.; Marler, L. E.; Pezzuto, J. M.; Fenical, W. J. Nat. Prod. 2010, 73, 1080
8. Perrin, C. L.; Rodgers, B. L.; O'Connor, J. M. J. Am. Chem. Soc. 2007, 129, 4795
9. Ziemert, N.; Podell, S.; Penn, K.; Badger, J.; Allen, E.; Jensen, P. R. PLoS One 2012, 7, e34064
10. McGlinchey, R. P.; Nett, M.; Moore, B. S. J. Am. Chem. Soc. 2008, 130, 2406
11. Udwary, D. W.; Zeigler, L.; Asolkar, R. N.; Singan, V.; Lapidus, A.; Fenical, W.; Jensen, P. R.; Moore, B. S. Proc. Natl. Acad. Sci. U.S.A. 2007, 104, 10376
12. Liu, W.; Christenson, S.; Standage, S.; Shen, B. Science 2002, 297, 1170
13. Liu, W.; Nonaka, K.; Nie, L. P.; Zhang, J.; Christenson, S. D.; Bae, J.; Van Lanen, S. G.; Zazopoulos, E.; Farnet, C. M.; Yang, C. F.; Shen, B. Chem. Biol. 2005, 12, 293
14. Eustáquio, A. S.; Pojer, F.; Noel, J. P.; Moore, B. S. Nat. Chem. Biol. 2008, 4, 69
15. Elespuru, R. K.; White, R. J. Cancer Res. 1983, 43, 2819
16. Van Lanen, S. G.; Oh, T.-J.; Liu, W.; Wendt-Pienkowski, E.; Shen, B. J. Am. Chem. Soc. 2007, 129, 13082
17. Fleming, F. Nat. Prod. Rep. 1999, 16, 597
18. Van Lanen, S.; Shen, B. Curr. Top. Med. Chem. 2008, 8, 448
19. Yonaha, K.; Nishie, M.; Aibara, S. J. Biol. Chem. 1992, 267, 12506
20. Olano, C.; Moss, S. J.; Brana, A. F.; Sheridan, R. M.; Math, V.; Weston, A. J.; Mendez, C.; Leadlay, P. F.; Wilkinson, B.; Salas, J. A. Mol. Microbiol. 2004, 52, 1745
21. Thibodeaux, C. J.; Melancìon, C. E., III; Liu, H.-W. Angew. Chem., Int. Ed. 2008, 47, 9814
22. Chen, H.; Zhao, Z.; Hallis, T. M.; Guo, Z.; Liu, H.-W. Angew. Chem., Int. Ed. 2001, 40, 607