Significant differences in genotoxicity induced by retrovirus integration in human T cells and induced pluripotent stem cells

Gene

Volumn 519, Issue 1, 2013, Pages 142-149

  Zheng, Weiyan ^a,b   Wang, Yingjia ^a   Chang, Tammy ^b   Huang, He ^a   Yee, Jiing Kuan ^b  

^a ZHEJIANG UNIVERSITY   (China)

^b CITY OF HOPE NATIONAL MEDICAL CENTER   (United States)

Author keywords

Gene expression; Genotoxicity; Induced pluripotent cells; Insertional mutagenesis; Retrovirus; Somatic cells

Indexed keywords

ARTICLE; BASIC RESEARCH; CELL CLONE; CHROMATIN; CONTROLLED STUDY; DNA INTEGRATION; DNA MODIFICATION; DOWN REGULATION; GENE ACTIVATION; GENE EXPRESSION; GENE SILENCING; GENETIC VARIABILITY; GENOTOXICITY; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; MAMMAL CELL; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; PROGENY; PROMOTER REGION; PROVIRUS; RETROVIRUS; RISK ASSESSMENT; T LYMPHOCYTE; TRANSCRIPTION INITIATION SITE;

CELL DIFFERENTIATION; CLONING, MOLECULAR; DNA DAMAGE; DOWN-REGULATION; GENETIC VECTORS; HEK293 CELLS; HUMANS; INDUCED PLURIPOTENT STEM CELLS; JURKAT CELLS; MUTAGENESIS, INSERTIONAL; RETROVIRIDAE; T-LYMPHOCYTES; TRANSFECTION;

MAMMALIA;

EID: 84875382790     PISSN: 03781119     EISSN: 18790038     Source Type: Journal    
DOI: 10.1016/j.gene.2013.01.009     Document Type: Article

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