Carnosic acid suppresses the production of amyloid-β 1-42 by inducing the metalloprotease gene TACE/ADAM17 in SH-SY5Y human neuroblastoma cells

Neuroscience Research

Volumn 75, Issue 2, 2013, Pages 94-102

  Meng, Pengfei ^a   Yoshida, Hidemi ^a   Matsumiya, Tomoh ^a   Imaizumi, Tadaatsu ^a   Tanji, Kunikazu ^a   Xing, Fei ^a   Hayakari, Ryo ^a   Dempoya, Junichi ^a   Tatsuta, Tetsuya ^a   Aizawa Yashiro, Tomomi ^b   Mimura, Junsei ^a   Kosaka, Kunio ^c   Itoh, Ken ^a   Satoh, Kei ^a  

^a HIROSAKI UNIVERSITY   (Japan)

^b HIROSAKI UNIVERSITY   (Japan)

^c Osaka City University Medical School   (Japan)

Author keywords

A 42; ADAM17; Alzheimer's disease; Carnosic acid; SH SY5Y; TACE

Indexed keywords

ALPHA SECRETASE; AMYLOID BETA PROTEIN[1-42]; BETA SECRETASE 1; CARNOSIC ACID; DISINTEGRIN; GAMMA SECRETASE; MATRIX METALLOPROTEINASE 17; SMALL INTERFERING RNA;

ALZHEIMER DISEASE; ARTICLE; CLINICAL ASSESSMENT; CONTROLLED STUDY; DRUG EFFECT; GENE EXPRESSION; GENE SILENCING; HUMAN; HUMAN CELL; NEUROBLASTOMA CELL; OUTCOME ASSESSMENT; PRIORITY JOURNAL; PROTEIN SECRETION;

ADAM PROTEINS; ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; AMYLOID BETA-PROTEIN PRECURSOR; AMYLOID PRECURSOR PROTEIN SECRETASES; CELL LINE, TUMOR; DITERPENES, ABIETANE; HUMANS; MEMBRANE PROTEINS; NEURONS; PEPTIDE FRAGMENTS; PLANT EXTRACTS;

EID: 84875374137     PISSN: 01680102     EISSN: 18728111     Source Type: Journal    
DOI: 10.1016/j.neures.2012.11.007     Document Type: Article

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