Synergistic effects of antibodies against high-mobility group box 1 and tumor necrosis factor-α antibodies on d -(+)-galactosamine hydrochloride/lipopolysaccharide-induced acute liver failure

FEBS Journal

Volumn 280, Issue 6, 2013, Pages 1409-1419

  Wang, Wei ^a,b   Sun, Li ^a,b   Deng, Yonghao ^a,b   Tang, Jie ^a  

^a INSTITUTE OF BIOPHYSICS   (China)

^b UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

Author keywords

d (+) galactosamine hydrochloride (d GalN); high mobility group box 1 (HMGB1); lipopolysaccharide (LPS); synergistic effect; tumor necrosis factor (TNF )

Indexed keywords

ALANINE AMINOTRANSFERASE; GALACTOSAMINE; HIGH MOBILITY GROUP B1 PROTEIN; HIGH MOBILITY GROUP B1 PROTEIN MONOCLONAL ANTIBODY; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 6; LACTATE DEHYDROGENASE; LIPOPOLYSACCHARIDE; MONOCLONAL ANTIBODY; SMALL INTERFERING RNA; THROMBOPLASTIN; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR ALPHA ANTIBODY; UNCLASSIFIED DRUG;

ACUTE LIVER FAILURE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DEATH; CONTROLLED STUDY; DISEASE SEVERITY; DRUG EFFICACY; DRUG POTENTIATION; DRUG RESPONSE; DRUG TARGETING; FEMALE; INFLAMMATION; LIVER INJURY; LIVER PROTECTION; MOUSE; NONHUMAN; POSITIVE FEEDBACK; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN SECRETION; SIGNAL TRANSDUCTION; UPREGULATION;

ALANINE TRANSAMINASE; ANIMALS; ANTIBODIES, MONOCLONAL; ANTIBODIES, NEUTRALIZING; DRUG SYNERGISM; DRUG-INDUCED LIVER INJURY; FEMALE; GALACTOSAMINE; HMGB1 PROTEIN; IMMUNOHISTOCHEMISTRY; INTERLEUKIN-6; LIPOPOLYSACCHARIDES; LIVER; LIVER FAILURE, ACUTE; MICE; MICE, INBRED C57BL; NECROSIS; NITRIC OXIDE SYNTHASE TYPE II; PROTEIN INTERACTION MAPPING; TUMOR NECROSIS FACTOR-ALPHA;

MUS;

EID: 84875368342     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/febs.12132     Document Type: Article

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