메뉴 건너뛰기




Volumn 8, Issue 3, 2013, Pages

PPARβ/δ Regulates Glucocorticoid- and Sepsis-Induced FOXO1 Activation and Muscle Wasting

Author keywords

[No Author keywords available]

Indexed keywords

3 [(4 ANILINO 2 METHOXYPHENYL)SULFAMOYL] 2 THENOIC ACID METHYL ESTER; ATROGIN 1; GLUCOCORTICOID; MUSCLE RING FINGER 1 PROTEIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA; TRANSCRIPTION FACTOR FKHR;

EID: 84875318722     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0059726     Document Type: Article
Times cited : (33)

References (87)
  • 1
    • 80052152680 scopus 로고    scopus 로고
    • Molecules modulating gene transcription during muscle wasting in cancer, sepsis and other critical illness
    • Aversa Z, Alamdari N, Hasselgren PO, (2011) Molecules modulating gene transcription during muscle wasting in cancer, sepsis and other critical illness. Crit Rev Clin Lab Sci 48: 71-86.
    • (2011) Crit Rev Clin Lab Sci , vol.48 , pp. 71-86
    • Aversa, Z.1    Alamdari, N.2    Hasselgren, P.O.3
  • 2
    • 77954348807 scopus 로고    scopus 로고
    • Corticosteroids and muscle wasting - role of transcription factors, nuclear cofactors, and hyperacetylation
    • Hasselgren PO, Alamdari N, Aversa Z, Gonnella P, Smith I, et al. (2010) Corticosteroids and muscle wasting - role of transcription factors, nuclear cofactors, and hyperacetylation. Curr Opin Clin Nutr Metabol Care 13: 423-428.
    • (2010) Curr Opin Clin Nutr Metabol Care , vol.13 , pp. 423-428
    • Hasselgren, P.O.1    Alamdari, N.2    Aversa, Z.3    Gonnella, P.4    Smith, I.5
  • 3
    • 42449133390 scopus 로고    scopus 로고
    • Mechanisms of glucocorticoid-induced myopathy
    • Schakman O, Gilson H, Thissen JP, (2008) Mechanisms of glucocorticoid-induced myopathy. J Endocrinol 197: 1-10.
    • (2008) J Endocrinol , vol.197 , pp. 1-10
    • Schakman, O.1    Gilson, H.2    Thissen, J.P.3
  • 5
    • 0035941020 scopus 로고    scopus 로고
    • Identification of ubiquitin ligases required for skeletal muscle atrophy
    • Bodine SC, Latres E, Baumheuter S, Lai VK, Nunez L, et al. (2001) Identification of ubiquitin ligases required for skeletal muscle atrophy. Science 294: 1704-1708.
    • (2001) Science , vol.294 , pp. 1704-1708
    • Bodine, S.C.1    Latres, E.2    Baumheuter, S.3    Lai, V.K.4    Nunez, L.5
  • 6
    • 0347285363 scopus 로고    scopus 로고
    • Multiple types of skeletal muscle atrophy involve a common program of changes in gene expression
    • Lecker SH, Jagoe RT, Gilbert A, Gomes M, Baracos V, et al. (2004) Multiple types of skeletal muscle atrophy involve a common program of changes in gene expression. FASEB J 18: 39-51.
    • (2004) FASEB J , vol.18 , pp. 39-51
    • Lecker, S.H.1    Jagoe, R.T.2    Gilbert, A.3    Gomes, M.4    Baracos, V.5
  • 7
    • 79953738995 scopus 로고    scopus 로고
    • The role and regulation of MAFbx/atrogin-1 and MuRF1 in skeletal muscle atrophy
    • Foletta VC, White LJ, Larsen AE, Leger B, Russell AP, (2011) The role and regulation of MAFbx/atrogin-1 and MuRF1 in skeletal muscle atrophy. Eur J Physiol 461: 325-335.
    • (2011) Eur J Physiol , vol.461 , pp. 325-335
    • Foletta, V.C.1    White, L.J.2    Larsen, A.E.3    Leger, B.4    Russell, A.P.5
  • 8
    • 0142200472 scopus 로고    scopus 로고
    • Fork head transcription factor FOXO1 (FKHR)-dependent induction of PDK4 gene expression in skeletal muscle during energy deprivation
    • Furuyama T, Kitayama K, Yamashita H, Mori N, (2003) Fork head transcription factor FOXO1 (FKHR)-dependent induction of PDK4 gene expression in skeletal muscle during energy deprivation. Biochem J 375: 365-371.
    • (2003) Biochem J , vol.375 , pp. 365-371
    • Furuyama, T.1    Kitayama, K.2    Yamashita, H.3    Mori, N.4
  • 9
    • 4544358547 scopus 로고    scopus 로고
    • Skeletal muscle FOXO1 (FKHR) transgenic mice have less skeletal muscle mass, down-regulated type 1 (slow twitch/red muscle) fiber genes, and impaired glycemic control
    • Kamei Y, Miura S, Suzuki M, Kai Y, Mizukami J, et al. (2004) Skeletal muscle FOXO1 (FKHR) transgenic mice have less skeletal muscle mass, down-regulated type 1 (slow twitch/red muscle) fiber genes, and impaired glycemic control. J Biol Chem 279: 41114-41123.
    • (2004) J Biol Chem , vol.279 , pp. 41114-41123
    • Kamei, Y.1    Miura, S.2    Suzuki, M.3    Kai, Y.4    Mizukami, J.5
  • 10
    • 34548450714 scopus 로고    scopus 로고
    • AMPK activation stimulates myofibrillar protein degradation and expression of atrophy-related ubiquitin ligases by increasing FOXO transcription factors in C2C12 myotubes
    • Nakashima K, Yakabe Y, (2007) AMPK activation stimulates myofibrillar protein degradation and expression of atrophy-related ubiquitin ligases by increasing FOXO transcription factors in C2C12 myotubes. Biosci Biotechnol Biochem 71: 1650-1656.
    • (2007) Biosci Biotechnol Biochem , vol.71 , pp. 1650-1656
    • Nakashima, K.1    Yakabe, Y.2
  • 11
    • 11144356337 scopus 로고    scopus 로고
    • Foxo transcription factors induce the atrophy-related ubiquitin ligase atrogin-1 and cause skeletal muscle atrophy
    • Sandri M, Sandri C, Gilbert A, Skurk C, Calabria E, at al, (2004) Foxo transcription factors induce the atrophy-related ubiquitin ligase atrogin-1 and cause skeletal muscle atrophy. Cell 117: 399-412.
    • (2004) Cell , vol.117 , pp. 399-412
    • Sandri, M.1    Sandri, C.2    Gilbert, A.3    Skurk, C.4    Calabria, E.5
  • 12
    • 77649180164 scopus 로고    scopus 로고
    • Sepsis increases the expression and activity of the transcription factor Forkhead Box O 1 (FOXO1) in skeletal muscle by a glucocorticoid-dependent mechanism
    • Smith I, Alamdari N, O'Neal P, Gonnella P, Aversa Z, et al. (2010) Sepsis increases the expression and activity of the transcription factor Forkhead Box O 1 (FOXO1) in skeletal muscle by a glucocorticoid-dependent mechanism. Int J Biochem Cell Biol 42: 701-711.
    • (2010) Int J Biochem Cell Biol , vol.42 , pp. 701-711
    • Smith, I.1    Alamdari, N.2    O'Neal, P.3    Gonnella, P.4    Aversa, Z.5
  • 14
    • 12144290563 scopus 로고    scopus 로고
    • Stress-dependent regulation of FoxO transcription factors by the Sirt1 deacetylase
    • Brunet A, Sweeney LB, Sturgill JF, Chua KF, Greer PL, et al. (2004) Stress-dependent regulation of FoxO transcription factors by the Sirt1 deacetylase. Science 303: 2011-2015.
    • (2004) Science , vol.303 , pp. 2011-2015
    • Brunet, A.1    Sweeney, L.B.2    Sturgill, J.F.3    Chua, K.F.4    Greer, P.L.5
  • 15
    • 16644382513 scopus 로고    scopus 로고
    • Human Foxo gene family
    • Katoh M, (2004) Human Foxo gene family. Int J Oncol 25: 1495-1500.
    • (2004) Int J Oncol , vol.25 , pp. 1495-1500
    • Katoh, M.1
  • 16
    • 2942726155 scopus 로고    scopus 로고
    • The ins and outs of FoxO shuttling: mechanism of FoxO translocation and transcriptional regulation
    • Van der Heide LP, Hoekmann MFM, Smidt MP, (2004) The ins and outs of FoxO shuttling: mechanism of FoxO translocation and transcriptional regulation. Biochem J 380: 297-309.
    • (2004) Biochem J , vol.380 , pp. 297-309
    • Van der Heide, L.P.1    Hoekmann, M.F.M.2    Smidt, M.P.3
  • 17
    • 35948935327 scopus 로고    scopus 로고
    • Ubiquitination, phosphorylation, and acetylation - triple threat in muscle wasting
    • Hasselgren PO, (2007) Ubiquitination, phosphorylation, and acetylation - triple threat in muscle wasting. J Cell Physiol 213: 679-689.
    • (2007) J Cell Physiol , vol.213 , pp. 679-689
    • Hasselgren, P.O.1
  • 19
    • 36448968532 scopus 로고    scopus 로고
    • FoxO3 coordinately activates protein degradation by the autophagic/lysosomal pathways in atrophying muscle
    • Zhao J, Brault JJ, Schild A, Cao P, Sandri M, et al. (2007) FoxO3 coordinately activates protein degradation by the autophagic/lysosomal pathways in atrophying muscle. Cell Metab 6: 472-483.
    • (2007) Cell Metab , vol.6 , pp. 472-483
    • Zhao, J.1    Brault, J.J.2    Schild, A.3    Cao, P.4    Sandri, M.5
  • 20
    • 47249119658 scopus 로고    scopus 로고
    • CD36-dependent regulation of muscle FoxO1 and PDK4 in the PPARβ/δ-mediated adaptation to metabolic stress
    • Nahle Z, Hsieh M, Pietka T, Coburn CT, Grimaldi PA, et al. (2008) CD36-dependent regulation of muscle FoxO1 and PDK4 in the PPARβ/δ-mediated adaptation to metabolic stress. J Biol Chem 283: 14317-14326.
    • (2008) J Biol Chem , vol.283 , pp. 14317-14326
    • Nahle, Z.1    Hsieh, M.2    Pietka, T.3    Coburn, C.T.4    Grimaldi, P.A.5
  • 21
    • 0034801882 scopus 로고    scopus 로고
    • Rat PPARs: quantitative analysis in adult rat tissues and regulation in fasting and refeeding
    • Escher P, Braissant O, Basu-Modak S, Michalik L, Wahli W, et al. (2001) Rat PPARs: quantitative analysis in adult rat tissues and regulation in fasting and refeeding. Endocrinology 142: 4195-4202.
    • (2001) Endocrinology , vol.142 , pp. 4195-4202
    • Escher, P.1    Braissant, O.2    Basu-Modak, S.3    Michalik, L.4    Wahli, W.5
  • 22
    • 43549113326 scopus 로고    scopus 로고
    • Quantitative expression patterns of peroxisome proliferator-activated receptor beta/delta (PPAR beta/delta) protein in mice
    • Girroir EE, Hollingshead HE, He P, Zhu B, Perdew GH, et al. (2008) Quantitative expression patterns of peroxisome proliferator-activated receptor beta/delta (PPAR beta/delta) protein in mice. Biochem Biophys Res Commun 371: 456-461.
    • (2008) Biochem Biophys Res Commun , vol.371 , pp. 456-461
    • Girroir, E.E.1    Hollingshead, H.E.2    He, P.3    Zhu, B.4    Perdew, G.H.5
  • 23
    • 48949102050 scopus 로고    scopus 로고
    • Role of peroxisome-proliferator-activated receptor beta/delta (PPAR beta/delta) in gastrointestinal tract function and disease
    • Peters JM, Hollingshead HE, Gonzalez FJ, (2008) Role of peroxisome-proliferator-activated receptor beta/delta (PPAR beta/delta) in gastrointestinal tract function and disease. Clin Sci 115: 107-127.
    • (2008) Clin Sci , vol.115 , pp. 107-127
    • Peters, J.M.1    Hollingshead, H.E.2    Gonzalez, F.J.3
  • 24
    • 70349177505 scopus 로고    scopus 로고
    • Sorting out the functional role(s) of peroxisome proliferator-activated receptor-beta/delta (PPAR beta/delta) in cell proliferation and cancer
    • Peters JM, Gonzalez FJ, (2009) Sorting out the functional role(s) of peroxisome proliferator-activated receptor-beta/delta (PPAR beta/delta) in cell proliferation and cancer. Biochim Biophys Acta 1796: 230-241.
    • (2009) Biochim Biophys Acta , vol.1796 , pp. 230-241
    • Peters, J.M.1    Gonzalez, F.J.2
  • 26
    • 0037135623 scopus 로고    scopus 로고
    • Fatty acid homeostasis and induction of lipid regulatory genes in skeletal muscles of peroxisome proliferator-activated receptor (PPAR) alpha knockout mice. Evidence for compensatory regulation by PPAR delta
    • Muoio DM, MacLean PS, Lang DB, Li S, Houmard JA, et al. (2002) Fatty acid homeostasis and induction of lipid regulatory genes in skeletal muscles of peroxisome proliferator-activated receptor (PPAR) alpha knockout mice. Evidence for compensatory regulation by PPAR delta. J Biol Chem 277: 26089-26097.
    • (2002) J Biol Chem , vol.277 , pp. 26089-26097
    • Muoio, D.M.1    MacLean, P.S.2    Lang, D.B.3    Li, S.4    Houmard, J.A.5
  • 27
    • 34547865385 scopus 로고    scopus 로고
    • PPARδ agonism induces a change in fuel metabolism and activation of an atrophy programme, but does not impair mitochondrial function in rat skeletal muscle
    • Constantin D, Constantin-Teodosiu D, Layfield R, Tsintzas K, Bennett AJ, et al. (2007) PPARδ agonism induces a change in fuel metabolism and activation of an atrophy programme, but does not impair mitochondrial function in rat skeletal muscle. J Physiol 583 (1) (): 381-390.
    • (2007) J Physiol , vol.583 , Issue.1 , pp. 381-390
    • Constantin, D.1    Constantin-Teodosiu, D.2    Layfield, R.3    Tsintzas, K.4    Bennett, A.J.5
  • 29
    • 34447130860 scopus 로고    scopus 로고
    • Are peroxisome proliferator-activated receptors involved in skeletal muscle wasting during experimental cancer cachexia? Role of β2-adrenergic agonists
    • Fuster G, Busquets S, Ametller E, Olivan M, Almendro V, et al. (2007) Are peroxisome proliferator-activated receptors involved in skeletal muscle wasting during experimental cancer cachexia? Role of β2-adrenergic agonists. Cancer Res 67: 6512-6579.
    • (2007) Cancer Res , vol.67 , pp. 6512-6579
    • Fuster, G.1    Busquets, S.2    Ametller, E.3    Olivan, M.4    Almendro, V.5
  • 30
    • 80051520474 scopus 로고    scopus 로고
    • C/EBPβ regulates dexamethasone-induced muscle cell atrophy and expression of atrogin-1 and MuRF1
    • Gonnella P, Alamdari N, Tizio S, Aversa Z, Petkova V, et al. (2011) C/EBPβ regulates dexamethasone-induced muscle cell atrophy and expression of atrogin-1 and MuRF1. J Cell Biochem 112: 1737-1748.
    • (2011) J Cell Biochem , vol.112 , pp. 1737-1748
    • Gonnella, P.1    Alamdari, N.2    Tizio, S.3    Aversa, Z.4    Petkova, V.5
  • 31
    • 54849413378 scopus 로고    scopus 로고
    • Dexamethasone and corticosterone induce similar, but not identical muscle wasting responses in cultured L6 and C2C12 myotubes
    • Menconi M, Gonnella P, Petkova V, Lecker S, Hasselgren PO, (2008) Dexamethasone and corticosterone induce similar, but not identical muscle wasting responses in cultured L6 and C2C12 myotubes. J Cell Biochem 105: 353-364.
    • (2008) J Cell Biochem , vol.105 , pp. 353-364
    • Menconi, M.1    Gonnella, P.2    Petkova, V.3    Lecker, S.4    Hasselgren, P.O.5
  • 32
    • 77951197658 scopus 로고    scopus 로고
    • The natural protective mechanism against hyperglycemia in vascular endothelial cells. Roles of the lipid peroxidation product 4-hydroxydodecadienal and peroxisome proliferator-activated receptor δ
    • Rihai Y, Sin-Malia Y, Cohen G, Alpert E, Gruzman A, et al. (2010) The natural protective mechanism against hyperglycemia in vascular endothelial cells. Roles of the lipid peroxidation product 4-hydroxydodecadienal and peroxisome proliferator-activated receptor δ. Diabetes 59: 808-818.
    • (2010) Diabetes , vol.59 , pp. 808-818
    • Rihai, Y.1    Sin-Malia, Y.2    Cohen, G.3    Alpert, E.4    Gruzman, A.5
  • 33
    • 80054786234 scopus 로고    scopus 로고
    • High-affinity peroxisome proliferator-activated receptor β/δ-specific ligands with pure antagonistic or inverse agonistic properties
    • Naruhn S, Toth PM, Adhikary T, Kaddatz K, Pape V, et al. (2011) High-affinity peroxisome proliferator-activated receptor β/δ-specific ligands with pure antagonistic or inverse agonistic properties. Mol Pharmacol 80: 828-838.
    • (2011) Mol Pharmacol , vol.80 , pp. 828-838
    • Naruhn, S.1    Toth, P.M.2    Adhikary, T.3    Kaddatz, K.4    Pape, V.5
  • 34
    • 0032185015 scopus 로고    scopus 로고
    • Dexamethasone stimulates proteasome- and calcium-dependent proteolysis in cultured L6 myotubes
    • Wang L, Luo GJ, Wang JJ, Hasselgren PO, (1998) Dexamethasone stimulates proteasome- and calcium-dependent proteolysis in cultured L6 myotubes. Shock 10: 298-306.
    • (1998) Shock , vol.10 , pp. 298-306
    • Wang, L.1    Luo, G.J.2    Wang, J.J.3    Hasselgren, P.O.4
  • 35
    • 0030051797 scopus 로고    scopus 로고
    • Energy-ubiquitin-dependent muscle proteolysis during sepsis in rats is regulated by glucocorticoids
    • Tiao G, Fagan J, Roegner V, Lieberman M, Wang JJ, et al. (1996) Energy-ubiquitin-dependent muscle proteolysis during sepsis in rats is regulated by glucocorticoids. J Clin Invest 97: 339-348.
    • (1996) J Clin Invest , vol.97 , pp. 339-348
    • Tiao, G.1    Fagan, J.2    Roegner, V.3    Lieberman, M.4    Wang, J.J.5
  • 36
    • 77955478905 scopus 로고    scopus 로고
    • Sepsis and glucocorticoids upregulate p300 and downregulate HDAC6 expression and activity in skeletal muscle
    • Alamdari N, Smith IJ, Aversa Z, Hasselgren PO, (2010) Sepsis and glucocorticoids upregulate p300 and downregulate HDAC6 expression and activity in skeletal muscle. Am J Physiol Regul Integr Comp Physiol 299: R509-R520.
    • (2010) Am J Physiol Regul Integr Comp Physiol , vol.299
    • Alamdari, N.1    Smith, I.J.2    Aversa, Z.3    Hasselgren, P.O.4
  • 37
    • 77957562997 scopus 로고    scopus 로고
    • Sepsis and glucocorticoids downregulate the expression of the nuclear cofactor PGC-1β in skeletal muscle
    • Menconi MJ, Arany ZP, Alamdari N, Aversa Z, Gonnella P, et al. (2010) Sepsis and glucocorticoids downregulate the expression of the nuclear cofactor PGC-1β in skeletal muscle. Am J Physiol Endocrinol Metab 299: E533-E543.
    • (2010) Am J Physiol Endocrinol Metab , vol.299
    • Menconi, M.J.1    Arany, Z.P.2    Alamdari, N.3    Aversa, Z.4    Gonnella, P.5
  • 38
    • 0025761863 scopus 로고
    • Effect of the glucocorticoid receptor antagonist RU 38486 on muscle protein breakdown in sepsis
    • Hall-Angerås M, Angerås U, Zamir O, Hasselgren PO, Fischer JE, (1991) Effect of the glucocorticoid receptor antagonist RU 38486 on muscle protein breakdown in sepsis. Surgery 109: 468-473.
    • (1991) Surgery , vol.109 , pp. 468-473
    • Hall-Angerås, M.1    Angerås, U.2    Zamir, O.3    Hasselgren, P.O.4    Fischer, J.E.5
  • 39
    • 0037401683 scopus 로고    scopus 로고
    • Sepsis upregulates the gene expression of multiple ubiquitin ligases in skeletal muscle
    • Wray CJ, Mammen JMV, Hershko D, Hasselgren PO, (2003) Sepsis upregulates the gene expression of multiple ubiquitin ligases in skeletal muscle. Int J Biochem Cell Biol 35: 698-705.
    • (2003) Int J Biochem Cell Biol , vol.35 , pp. 698-705
    • Wray, C.J.1    Mammen, J.M.V.2    Hershko, D.3    Hasselgren, P.O.4
  • 40
    • 0026438314 scopus 로고
    • Is the metabolic response to sepsis in skeletal muscle different in infants and adults? An experimental study in rats
    • Zamir O, Hasselgren PO, Frederick JA, Fischer JE, (1992) Is the metabolic response to sepsis in skeletal muscle different in infants and adults? An experimental study in rats. J Pediatr Surg 27: 1399-1403.
    • (1992) J Pediatr Surg , vol.27 , pp. 1399-1403
    • Zamir, O.1    Hasselgren, P.O.2    Frederick, J.A.3    Fischer, J.E.4
  • 41
    • 0031018516 scopus 로고    scopus 로고
    • Sepsis is associated with increased mRNAs of the ubiquitin-proteasome proteolytic pathway in human skeletal muscle
    • Tiao G, Hobler S, Wang JJ, Meyer TA, Luchette FA, et al. (1997) Sepsis is associated with increased mRNAs of the ubiquitin-proteasome proteolytic pathway in human skeletal muscle. J Clin Invest 99: 163-168.
    • (1997) J Clin Invest , vol.99 , pp. 163-168
    • Tiao, G.1    Hobler, S.2    Wang, J.J.3    Meyer, T.A.4    Luchette, F.A.5
  • 42
    • 79959960189 scopus 로고    scopus 로고
    • Administration of PPARβ/δ agonist reduces copper-induced liver damage in mice: possible implications in clinical practice
    • Sanchez-Siles AA, Ishimura N, Rumi MA, Tamagawa Y, Ito S, et al. (2011) Administration of PPARβ/δ agonist reduces copper-induced liver damage in mice: possible implications in clinical practice. J Clin Biochem Nutr 49: 42-49.
    • (2011) J Clin Biochem Nutr , vol.49 , pp. 42-49
    • Sanchez-Siles, A.A.1    Ishimura, N.2    Rumi, M.A.3    Tamagawa, Y.4    Ito, S.5
  • 43
    • 0032797384 scopus 로고    scopus 로고
    • Sepsis stimulates release of myofilaments in skeletal muscle by a calcium-dependent mechanism
    • Williams AB, DeCourten-Meyers GM, Fischer JE, Luo G, Sun X, et al. (1999) Sepsis stimulates release of myofilaments in skeletal muscle by a calcium-dependent mechanism. FASEB J 13: 1435-1443.
    • (1999) FASEB J , vol.13 , pp. 1435-1443
    • Williams, A.B.1    DeCourten-Meyers, G.M.2    Fischer, J.E.3    Luo, G.4    Sun, X.5
  • 44
    • 84862750591 scopus 로고    scopus 로고
    • Multiple muscle wasting-related transcription factors are acetylated in dexamethasone-treated muscle cells
    • Chamberlain W, Gonnella P, Alamdari N, Aversa Z, Hasselgren PO, (2012) Multiple muscle wasting-related transcription factors are acetylated in dexamethasone-treated muscle cells. Biochem Cell Biol 90: 200-208.
    • (2012) Biochem Cell Biol , vol.90 , pp. 200-208
    • Chamberlain, W.1    Gonnella, P.2    Alamdari, N.3    Aversa, Z.4    Hasselgren, P.O.5
  • 45
    • 12444289447 scopus 로고    scopus 로고
    • Novel selective small molecule agonists for peroxisome proliferator-activated receptor δ (PPARδ) - synthesis and biological activity
    • Sznaidman ML, Haffner CD, Maloney PR, Fivush A, Chao E, et al. (2003) Novel selective small molecule agonists for peroxisome proliferator-activated receptor δ (PPARδ) - synthesis and biological activity. Bioorg Med Chem Lett 13: 1517-1521.
    • (2003) Bioorg Med Chem Lett , vol.13 , pp. 1517-1521
    • Sznaidman, M.L.1    Haffner, C.D.2    Maloney, P.R.3    Fivush, A.4    Chao, E.5
  • 46
    • 38749152401 scopus 로고    scopus 로고
    • Identification and characterization of a selective peroxisome proliferator-activated receptor β/δ (nrlc2) antagonist
    • Shearer BG, Steger DJ, Way JM, Stanley TB, Lobe DC, et al. (2008) Identification and characterization of a selective peroxisome proliferator-activated receptor β/δ (nrlc2) antagonist. Mol Endocrinol 22: 523-529.
    • (2008) Mol Endocrinol , vol.22 , pp. 523-529
    • Shearer, B.G.1    Steger, D.J.2    Way, J.M.3    Stanley, T.B.4    Lobe, D.C.5
  • 47
    • 2942726155 scopus 로고    scopus 로고
    • The ins and outs of FoxO shuttling: mechanisms of FoxO translocation and transcriptional regulation
    • Van der Heide LP, Hoekman MFM, Smidt MP, (2004) The ins and outs of FoxO shuttling: mechanisms of FoxO translocation and transcriptional regulation. Biochem J 380: 297-309.
    • (2004) Biochem J , vol.380 , pp. 297-309
    • Van der Heide, L.P.1    Hoekman, M.F.M.2    Smidt, M.P.3
  • 48
    • 1342264308 scopus 로고    scopus 로고
    • Mammalian SIRT1 represses forkhead transcription factors
    • Motta MC, Divecha N, Lemieux M, Kamel C, Chen D, et al. (2004) Mammalian SIRT1 represses forkhead transcription factors. Cell 116: 551-563.
    • (2004) Cell , vol.116 , pp. 551-563
    • Motta, M.C.1    Divecha, N.2    Lemieux, M.3    Kamel, C.4    Chen, D.5
  • 49
    • 24344499875 scopus 로고    scopus 로고
    • The coactivator p300 directly acetylates the forkhead transcription factor Foxo1 and stimulates Foxo1-induced transcription
    • Perrot V, Rechter MM, (2005) The coactivator p300 directly acetylates the forkhead transcription factor Foxo1 and stimulates Foxo1-induced transcription. Mol Endocrinol 19: 2283-2298.
    • (2005) Mol Endocrinol , vol.19 , pp. 2283-2298
    • Perrot, V.1    Rechter, M.M.2
  • 50
    • 84855812532 scopus 로고    scopus 로고
    • Resveratrol prevents dexamethasone-induced expression of the muscle atrophy-related ubiquitin ligases atrogin-1 and MuRF1 in cultured myotubes through a SIRT1-dependent mechanism
    • Alamdari N, Aversa Z, Castillero E, Gurav A, et al. (2012) Resveratrol prevents dexamethasone-induced expression of the muscle atrophy-related ubiquitin ligases atrogin-1 and MuRF1 in cultured myotubes through a SIRT1-dependent mechanism. Biochem Biophys Res Commun 417: 528-533.
    • (2012) Biochem Biophys Res Commun , vol.417 , pp. 528-533
    • Alamdari, N.1    Aversa, Z.2    Castillero, E.3    Gurav, A.4
  • 51
    • 0033305164 scopus 로고    scopus 로고
    • Thiazolidinedione effects on glucocorticoid receptor-mediated gene transcription and differentiation in osteoblastic cells
    • Johnson TE, Vogel R, Rutledge SJ, Rodan G, Schmidt A, (1999) Thiazolidinedione effects on glucocorticoid receptor-mediated gene transcription and differentiation in osteoblastic cells. Endocrinology 140: 3245-3254.
    • (1999) Endocrinology , vol.140 , pp. 3245-3254
    • Johnson, T.E.1    Vogel, R.2    Rutledge, S.J.3    Rodan, G.4    Schmidt, A.5
  • 52
    • 0028003839 scopus 로고
    • Regulation of the peroxisome proliferator-activated receptor α gene by glucocorticoids
    • Lemberger T, Staels B, Saladin R, Desvergne B, Auwerx J, et al. (1994) Regulation of the peroxisome proliferator-activated receptor α gene by glucocorticoids. J Biol Chem 269: 24527-24530.
    • (1994) J Biol Chem , vol.269 , pp. 24527-24530
    • Lemberger, T.1    Staels, B.2    Saladin, R.3    Desvergne, B.4    Auwerx, J.5
  • 53
    • 0030060358 scopus 로고    scopus 로고
    • Expression of the peroxisome proliferator-activated receptor α gene is stimulated by stress and follows a diurnal rhythm
    • Lemberger T, Saladin R, Vázquez M, Assimacopoulos F, Staels B, et al. (1996) Expression of the peroxisome proliferator-activated receptor α gene is stimulated by stress and follows a diurnal rhythm. J Biol Chem 271: 1764-1769.
    • (1996) J Biol Chem , vol.271 , pp. 1764-1769
    • Lemberger, T.1    Saladin, R.2    Vázquez, M.3    Assimacopoulos, F.4    Staels, B.5
  • 54
    • 13244279654 scopus 로고    scopus 로고
    • Differential regulation of chemokine expression by peroxisome proliferator-activated receptor γ agonists. Interactions with glucocorticoids and β2-agonists
    • Nie M, Corbett L, Knox AJ, Pang L, (2005) Differential regulation of chemokine expression by peroxisome proliferator-activated receptor γ agonists. Interactions with glucocorticoids and β2-agonists. J Biol Chem 280: 2550-2561.
    • (2005) J Biol Chem , vol.280 , pp. 2550-2561
    • Nie, M.1    Corbett, L.2    Knox, A.J.3    Pang, L.4
  • 55
    • 0002708343 scopus 로고
    • RU38486: an original multifaceted antihormone in vivo
    • Hawthorne, New York: Walter de Gruyter and Co
    • Philibert D (1984) RU38486: an original multifaceted antihormone in vivo. Adrenal Steroid Antagonism. Hawthorne, New York: Walter de Gruyter and Co.
    • (1984) Adrenal Steroid Antagonism
    • Philibert, D.1
  • 56
    • 78049258823 scopus 로고    scopus 로고
    • Sepsis downregulates myostatin mRNA levels without altering myostatin protein levels in skeletal muscle
    • Smith IJ, Aversa Z, Alamdari N, Petkova V, Hasselgren PO, (2010) Sepsis downregulates myostatin mRNA levels without altering myostatin protein levels in skeletal muscle. J Cell Biochem 111: 1059-1073.
    • (2010) J Cell Biochem , vol.111 , pp. 1059-1073
    • Smith, I.J.1    Aversa, Z.2    Alamdari, N.3    Petkova, V.4    Hasselgren, P.O.5
  • 58
    • 70350520677 scopus 로고    scopus 로고
    • Physical inactivity and muscle weakness in the critically ill
    • Chambers MA, Moylan JS, Reid MB, (2009) Physical inactivity and muscle weakness in the critically ill. Crit Care Med 37: S337-S346.
    • (2009) Crit Care Med , vol.37
    • Chambers, M.A.1    Moylan, J.S.2    Reid, M.B.3
  • 60
    • 70350510281 scopus 로고    scopus 로고
    • Legacy of intensive care unit-acquired weakness
    • Herridge MS, (2009) Legacy of intensive care unit-acquired weakness. Crit Care Med 37: S457-S46.1.
    • (2009) Crit Care Med , vol.37 , pp. 446-457
    • Herridge, M.S.1
  • 61
    • 41449113183 scopus 로고    scopus 로고
    • Rapid disuse atrophy of diaphragm fibers in mechanically ventilated humans
    • Levine S, Nguyen T, Taylor N, Friscia ME, Budak MT, et al. (2008) Rapid disuse atrophy of diaphragm fibers in mechanically ventilated humans. N Engl J Med 358: 1327-1335.
    • (2008) N Engl J Med , vol.358 , pp. 1327-1335
    • Levine, S.1    Nguyen, T.2    Taylor, N.3    Friscia, M.E.4    Budak, M.T.5
  • 62
    • 4544355465 scopus 로고    scopus 로고
    • Triacylglycerol accumulation in human obesity and type 2 diabetes is associated with increased rates of muscle fatty acid transport and increased sarcolemmal FAT/CD36
    • Bonen A, Parolin ML, Steinberg GR, Calles-Escandon J, Tandon NN, et al. (2004) Triacylglycerol accumulation in human obesity and type 2 diabetes is associated with increased rates of muscle fatty acid transport and increased sarcolemmal FAT/CD36. FASEB J 18: 1144-1146.
    • (2004) FASEB J , vol.18 , pp. 1144-1146
    • Bonen, A.1    Parolin, M.L.2    Steinberg, G.R.3    Calles-Escandon, J.4    Tandon, N.N.5
  • 63
    • 65649133062 scopus 로고    scopus 로고
    • In obese rat muscle transport of palmitate is increased and is channeled to triacylglycerol storage despite an increase in mitochondrial palmitate oxidation
    • Holloway GP, Benton CR, Mullen KL, Yoshida Y, Snook LA, et al. (2009) In obese rat muscle transport of palmitate is increased and is channeled to triacylglycerol storage despite an increase in mitochondrial palmitate oxidation. Am J Physiol Endocrinol Metab 296: E738-E747.
    • (2009) Am J Physiol Endocrinol Metab , vol.296
    • Holloway, G.P.1    Benton, C.R.2    Mullen, K.L.3    Yoshida, Y.4    Snook, L.A.5
  • 65
    • 84861918964 scopus 로고    scopus 로고
    • Dexamethasone facilitates lipid accumulation in chicken skeletal muscle
    • Wang XJ, Song ZG, Jiao HC, Lin H, (2011) Dexamethasone facilitates lipid accumulation in chicken skeletal muscle. Stress 2012 15(4): 443-56.
    • (2011) Stress 2012 , vol.15 , Issue.4 , pp. 443-456
    • Wang, X.J.1    Song, Z.G.2    Jiao, H.C.3    Lin, H.4
  • 66
    • 0141497509 scopus 로고    scopus 로고
    • How do corticosteroids work in asthma?
    • Barnes PJ, Adcock IM, (2003) How do corticosteroids work in asthma? Ann Intern Med 139: 359-370.
    • (2003) Ann Intern Med , vol.139 , pp. 359-370
    • Barnes, P.J.1    Adcock, I.M.2
  • 67
    • 0034721937 scopus 로고    scopus 로고
    • Ligand type-specific interactions of peroxisome proliferator-activated receptor γ with transcriptional coactivators
    • Kodera Y, Takeyama K, Murayama A, Suzawa M, Masuhiro Y, et al. (2000) Ligand type-specific interactions of peroxisome proliferator-activated receptor γ with transcriptional coactivators. J Biol Chem 275: 33201-33204.
    • (2000) J Biol Chem , vol.275 , pp. 33201-33204
    • Kodera, Y.1    Takeyama, K.2    Murayama, A.3    Suzawa, M.4    Masuhiro, Y.5
  • 68
    • 0034099382 scopus 로고    scopus 로고
    • Differential interaction of steroid hormone receptors with LXXLL motifs in SRC-1a depends on residues flanking the motif
    • Needham M, Raines S, McPheat J, Stacey C, et al. (2000) Differential interaction of steroid hormone receptors with LXXLL motifs in SRC-1a depends on residues flanking the motif. J Steroid Biochem Mol Biol 72: 35-46.
    • (2000) J Steroid Biochem Mol Biol , vol.72 , pp. 35-46
    • Needham, M.1    Raines, S.2    McPheat, J.3    Stacey, C.4
  • 69
    • 5444262078 scopus 로고    scopus 로고
    • Iκκβ/NF-κB activation causes severe muscle wasting in mice
    • Cai D, Frantz JD, Tawa NE Jr, Melendez PA, Oh BC, et al. (2004) Iκκβ/NF-κB activation causes severe muscle wasting in mice. Cell 119: 285-298.
    • (2004) Cell , vol.119 , pp. 285-298
    • Cai, D.1    Frantz, J.D.2    Tawa Jr., N.E.3    Melendez, P.A.4    Oh, B.C.5
  • 70
    • 0034810476 scopus 로고    scopus 로고
    • The transcription factors NF-kB and AP-1 are differentially regulated in skeletal muscle during sepsis
    • Penner CG, Gang G, Wray C, Fischer JE, Hasselgren PO, (2001) The transcription factors NF-kB and AP-1 are differentially regulated in skeletal muscle during sepsis. Biochem Biophys Res Commun 281: 1331-1336.
    • (2001) Biochem Biophys Res Commun , vol.281 , pp. 1331-1336
    • Penner, C.G.1    Gang, G.2    Wray, C.3    Fischer, J.E.4    Hasselgren, P.O.5
  • 71
    • 59649104233 scopus 로고    scopus 로고
    • The IkB kinases IKKα and IKKβ are necessary and sufficient for skeletal muscle atrophy
    • Van Gammeren D, Damrauer JS, Jackman RW, Kandarian S, (2009) The IkB kinases IKKα and IKKβ are necessary and sufficient for skeletal muscle atrophy. FASEB J 23: 362-370.
    • (2009) FASEB J , vol.23 , pp. 362-370
    • Van Gammeren, D.1    Damrauer, J.S.2    Jackman, R.W.3    Kandarian, S.4
  • 72
    • 80054915078 scopus 로고    scopus 로고
    • C/EBPβ mediates tumor-induced ubiquitin ligase atrogin-1/MAFbx upregulation and muscle wasting
    • Zhang G, Jin B, Li YP, (2011) C/EBPβ mediates tumor-induced ubiquitin ligase atrogin-1/MAFbx upregulation and muscle wasting. EMBO J 30: 4323-4335.
    • (2011) EMBO J , vol.30 , pp. 4323-4335
    • Zhang, G.1    Jin, B.2    Li, Y.P.3
  • 73
    • 77950202392 scopus 로고    scopus 로고
    • Activation of peroxisome proliferator-activated receptor-δ by GW 501516 prevents fatty acid-induced nuclear factor-kB activation and insulin resistance in skeletal muscle cells
    • Coll T, Alvarez-Guardia D, Barroso E, Gómez-Foix AM, Palomer X, et al. (2010) Activation of peroxisome proliferator-activated receptor-δ by GW 501516 prevents fatty acid-induced nuclear factor-kB activation and insulin resistance in skeletal muscle cells. Endocrinology 151: 1560-1569.
    • (2010) Endocrinology , vol.151 , pp. 1560-1569
    • Coll, T.1    Alvarez-Guardia, D.2    Barroso, E.3    Gómez-Foix, A.M.4    Palomer, X.5
  • 74
    • 20144387426 scopus 로고    scopus 로고
    • Direct activation of glucose transport in primary human myotubes after activation of peroxisome proliferator-activated receptor δ
    • Krämer DK, Al-Khalili L, Perrini S, Skogsberg J, Wretenberg P, et al. (2005) Direct activation of glucose transport in primary human myotubes after activation of peroxisome proliferator-activated receptor δ. Diabetes 54: 1157-1163.
    • (2005) Diabetes , vol.54 , pp. 1157-1163
    • Krämer, D.K.1    Al-Khalili, L.2    Perrini, S.3    Skogsberg, J.4    Wretenberg, P.5
  • 75
    • 0642303113 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor δ controls muscle development and oxidative capability
    • Luquet S, Lopez-Soriano J, Holst D, Fredenrich A, Melki J, et al. (2003) Peroxisome proliferator-activated receptor δ controls muscle development and oxidative capability. FASEB J 17: 2299-2301.
    • (2003) FASEB J , vol.17 , pp. 2299-2301
    • Luquet, S.1    Lopez-Soriano, J.2    Holst, D.3    Fredenrich, A.4    Melki, J.5
  • 76
    • 33750427891 scopus 로고    scopus 로고
    • PGC-1α expression is controlled in skeletal muscle by PPARβ, whose ablation results in fiber-type switching, obesity, and type 2 diabetes
    • Schuler M, Ali F, Chambon C, Duteil D, Bornert JM, et al. (2006) PGC-1α expression is controlled in skeletal muscle by PPARβ, whose ablation results in fiber-type switching, obesity, and type 2 diabetes. Cell Metab 4: 407-414.
    • (2006) Cell Metab , vol.4 , pp. 407-414
    • Schuler, M.1    Ali, F.2    Chambon, C.3    Duteil, D.4    Bornert, J.M.5
  • 78
    • 79958046938 scopus 로고    scopus 로고
    • Insulin resistance in critical illness
    • Dhar A, Castillo L, (2011) Insulin resistance in critical illness. Curr Opin Pediatr 23: 269-274.
    • (2011) Curr Opin Pediatr , vol.23 , pp. 269-274
    • Dhar, A.1    Castillo, L.2
  • 79
    • 33747619854 scopus 로고    scopus 로고
    • Insulin resistance accelerates muscle protein degradation: Activation of the ubiquitin-proteasome pathway by defects in muscle cell signaling
    • Wang X, Hu Z, Hu J, Du J, Mitch WE, (2006) Insulin resistance accelerates muscle protein degradation: Activation of the ubiquitin-proteasome pathway by defects in muscle cell signaling. Endocrinology 147: 4160-4168.
    • (2006) Endocrinology , vol.147 , pp. 4160-4168
    • Wang, X.1    Hu, Z.2    Hu, J.3    Du, J.4    Mitch, W.E.5
  • 80
    • 57349176638 scopus 로고    scopus 로고
    • The oxidative stress and the mitochondrial dysfunction caused by endotoxemia are prevented by alpha-lipoic acid
    • Vanasco V, Cimolai MC, Evelson P, Alvarez S, (2008) The oxidative stress and the mitochondrial dysfunction caused by endotoxemia are prevented by alpha-lipoic acid. Free Radic Res 42: 815-823.
    • (2008) Free Radic Res , vol.42 , pp. 815-823
    • Vanasco, V.1    Cimolai, M.C.2    Evelson, P.3    Alvarez, S.4
  • 81
    • 34548173277 scopus 로고    scopus 로고
    • Mitochondrial function in sepsis: respiratory versus leg muscle
    • Fredriksson K, Rooyackers O, (2007) Mitochondrial function in sepsis: respiratory versus leg muscle. Crit Care Med 35: S449-S453.
    • (2007) Crit Care Med , vol.35
    • Fredriksson, K.1    Rooyackers, O.2
  • 82
    • 33748306082 scopus 로고    scopus 로고
    • Short-term activation of peroxisome proliferator-activated receptor β/δ increases fatty acid oxidation but does not restore insulin action in muscle cells from type 2 diabetic patients
    • Debard C, Cozzone D, Ricard N, Vouillarmet J, Disse E, et al. (2006) Short-term activation of peroxisome proliferator-activated receptor β/δ increases fatty acid oxidation but does not restore insulin action in muscle cells from type 2 diabetic patients. J Mol Med 84: 747-752.
    • (2006) J Mol Med , vol.84 , pp. 747-752
    • Debard, C.1    Cozzone, D.2    Ricard, N.3    Vouillarmet, J.4    Disse, E.5
  • 83
    • 33646092073 scopus 로고    scopus 로고
    • PPARδ activator GW-501516 has no acute effect on glucose transport in skeletal muscle
    • Terada S, Wicke S, Holloszy JO, Han DH, (2006) PPARδ activator GW-501516 has no acute effect on glucose transport in skeletal muscle. Am J Physiol Endocrinol Metab 290: E607-E611.
    • (2006) Am J Physiol Endocrinol Metab , vol.290
    • Terada, S.1    Wicke, S.2    Holloszy, J.O.3    Han, D.H.4
  • 84
    • 34548695918 scopus 로고    scopus 로고
    • The PPARδ agonist, GW501516, promotes fatty acid oxidation but has no direct effect on glucose utilization or insulin sensitivity in rat L6 skeletal muscle cells
    • Dimopoulos N, Watson M, Green C, Hundal HS, (2007) The PPARδ agonist, GW501516, promotes fatty acid oxidation but has no direct effect on glucose utilization or insulin sensitivity in rat L6 skeletal muscle cells. FEBS Lett 581: 4743-4748.
    • (2007) FEBS Lett , vol.581 , pp. 4743-4748
    • Dimopoulos, N.1    Watson, M.2    Green, C.3    Hundal, H.S.4
  • 85
    • 77955477569 scopus 로고    scopus 로고
    • Oral administration of a PPAR-δ agonist worsens, not improves, maximal insulin-stimulated glucose transport in skeletal muscle of different fibers
    • Cresser J, Bonen A, Chabowski A, Stefanyk LE, Gulli R, et al. (2010) Oral administration of a PPAR-δ agonist worsens, not improves, maximal insulin-stimulated glucose transport in skeletal muscle of different fibers. Am J Physiol Regul Integr Comp Physiol 299: R470-R479.
    • (2010) Am J Physiol Regul Integr Comp Physiol , vol.299
    • Cresser, J.1    Bonen, A.2    Chabowski, A.3    Stefanyk, L.E.4    Gulli, R.5
  • 86
    • 33845962552 scopus 로고    scopus 로고
    • Activation of PPAR-δ in isolated rat skeletal muscle switches fuel preference from glucose to fatty acids
    • Brunnmair B, Staniek K, Dörig J, Szöcs Z, Stadlbauer K, et al. (2006) Activation of PPAR-δ in isolated rat skeletal muscle switches fuel preference from glucose to fatty acids. Diabetologia 49: 2713-2722.
    • (2006) Diabetologia , vol.49 , pp. 2713-2722
    • Brunnmair, B.1    Staniek, K.2    Dörig, J.3    Szöcs, Z.4    Stadlbauer, K.5
  • 87
    • 0035142151 scopus 로고    scopus 로고
    • Mitochondrial medicine - molecular pathology of defective oxidative phosphorylation
    • Fosslien E, (2001) Mitochondrial medicine - molecular pathology of defective oxidative phosphorylation. Ann Clin Lab Sci 31: 25-67.
    • (2001) Ann Clin Lab Sci , vol.31 , pp. 25-67
    • Fosslien, E.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.