Chronic valproic acid administration impairs contextual memory and dysregulates hippocampal GSK-3β in rats

Pharmacology Biochemistry and Behavior

Volumn 106, Issue , 2013, Pages 8-15

  Sintoni, Silvia ^a   Kurtys, Ewelina ^a,b   Scandaglia, Marilyn ^a,c   Contestabile, Antonio ^a   Monti, Barbara ^a  

^a UNIVERSITY OF BOLOGNA   (Italy)

^b UNIVERSITY OF GRONINGEN   (Netherlands)

^c MIGUEL HERNÁNDEZ UNIVERSITY   (Spain)

Author keywords

GSK 3 inhibition; Hippocampal neurogenesis; Hippocampal dependent memory; Histone deacetylase inhibition; Valproic acid

Indexed keywords

DOUBLECORTIN; GLYCOGEN SYNTHASE KINASE 3BETA; HISTONE DEACETYLASE; HISTONE H3; VALPROIC ACID;

AMNESIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; DENTATE GYRUS; ENZYME ACTIVITY; FEAR; GENETIC TRANSCRIPTION; HIPPOCAMPUS; HISTONE ACETYLATION; LEARNING; LONG TERM CARE; MALE; MEMORY CONSOLIDATION; MEMORY DISORDER; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; PLASTICITY; PRIORITY JOURNAL; PROTEIN MODIFICATION; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; RAT; SURVIVAL; TREATMENT DURATION;

ANIMALS; BLOTTING, WESTERN; FEAR; GLYCOGEN SYNTHASE KINASE 3; HIPPOCAMPUS; MALE; MEMORY; NEUROGENESIS; RATS; RATS, WISTAR; VALPROIC ACID;

ANIMALIA; RATTUS; RODENTIA;

EID: 84875310844     PISSN: 00913057     EISSN: 18735177     Source Type: Journal    
DOI: 10.1016/j.pbb.2013.02.013     Document Type: Article

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