Oxymatrine protects against myocardial injury via inhibition of JAK2/STAT3 signaling in rat septic shock

Molecular Medicine Reports

Volumn 7, Issue 4, 2013, Pages 1293-1299

  Zhang, Minghao ^a   Wang, Xiuyu ^a   Wang, Xiumei ^b   Hou, Xiaolin ^a   Teng, Peng ^a   Jiang, Yideng ^a   Zhang, Linna ^a   Yang, Xiaoling ^a   Tian, Jue ^a   Li, Guizhong ^a   Cao, Jun ^a   Xu, Hua ^a   Li, Yunhong ^a   Wang, Yin ^a  

^a NINGXIA MEDICAL UNIVERSITY   (China)

^b Department of Pediatrics   (China)

Author keywords

JAK2 STAT3; Myocardial injury; Oxymatrine; Septic shock

Indexed keywords

DEXAMETHASONE; INTERLEUKIN 1BETA; JANUS KINASE 2; MESSENGER RNA; OXYMATRINE; STAT3 PROTEIN; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; DIASTOLE; DRUG EFFECT; ENZYME INHIBITION; HEART FUNCTION; HEART MUSCLE CONTRACTILITY; HEART MUSCLE INJURY; HEART PROTECTION; HEART RATE; MALE; MEAN ARTERIAL PRESSURE; NONHUMAN; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEPTIC SHOCK; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ALKALOIDS; ANIMALS; HEART INJURIES; HUMANS; INTERLEUKIN-1BETA; JANUS KINASE 2; PHOSPHORYLATION; PLANT EXTRACTS; QUINOLIZINES; RATS; SHOCK, SEPTIC; SIGNAL TRANSDUCTION; SOPHORA; STAT3 TRANSCRIPTION FACTOR;

EID: 84875257549     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2013.1315     Document Type: Article

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