Characterization of a refinement of the "pylorus ligation" model of rat gastric ulceration resulting in "no pain" and a more specific pharmacological response

Journal of Pharmacological and Toxicological Methods

Volumn 67, Issue 2, 2013, Pages 121-128

  Monteiro, Karin M ^a   Spindola, Humberto M ^a   Possenti, Ana ^a   Tinti, Sirlene V ^a   Ruiz, Ana L T G ^a   Longato, Giovanna B ^a   Fiorito, Giovanna F ^a   Marchetti, Gabriela M ^a   Shiozawa, Larissa ^a   Piloni, Bárbara U ^b   de Oliveira, Ana C ^c   Miyagawa, Livia M ^d   Carvalho, João E ^a  

^a UNIVERSITY OF CAMPINAS   (Brazil)

^b UNIVERSITY OF JOINVILLE REGION   (Brazil)

^c FEDERAL UNIVERSITY OF PARÁ   (Brazil)

^d Centre for Afro food Valorisation of Amazonian Bioactive Compounds (CVACBA)   (Brazil)

Author keywords

Anesthesia; Gastric secretion; Pylorus ligation; Rats; Refinement; Stress

Indexed keywords

BETHANECHOL; CIMETIDINE; HISTAMINE; PENTAGASTRIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; EXPERIMENTAL ANIMAL WELFARE; EXPERIMENTAL LIGATION; LATENT PERIOD; MALE; NONHUMAN; POSTOPERATIVE PAIN; PYLORUS LIGATION; RAT; STOMACH ACID SECRETION; STOMACH PH; STOMACH ULCER;

ANIMALS; BETHANECHOL; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; GASTRIC ACID; HISTAMINE; LIGATION; MALE; PAIN, POSTOPERATIVE; PENTAGASTRIN; PYLORUS; RATS; RATS, WISTAR; SENSITIVITY AND SPECIFICITY; STOMACH; STOMACH ULCER; STRESS, PHYSIOLOGICAL;

ANIMALIA; RATTUS;

EID: 84875251269     PISSN: 10568719     EISSN: 1873488X     Source Type: Journal    
DOI: 10.1016/j.vascn.2012.09.002     Document Type: Article

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