Cholinergic system under aluminium toxicity in rat brain

Toxicology International

Volumn 17, Issue 2, 2010, Pages 106-112

  Yellamma, K ^a   Saraswathamma, S ^a   Kumari, B Nirmala ^a  

^a SRI VENKATESWARA UNIVERSITY   (India)

Author keywords

Aluminium acetate; behavioral changes; cholinergic system; rat brain

Indexed keywords

ACETYLCHOLINE; ACETYLCHOLINESTERASE; ALUMINUM ACETATE;

ACETYLCHOLINE BRAIN LEVEL; ADIPSIA; ANIMAL EXPERIMENT; APHAGIA; ARTICLE; BEHAVIOR CHANGE; BRAIN CORTEX; BRAIN REGION; BRAIN TOXICITY; CEREBELLUM; CHOLINERGIC SYSTEM; DETOXIFICATION; ENZYME ACTIVITY; FATIGUE; HIPPOCAMPUS; HYPOKINESIA; HYPOTHALAMUS; MALE; NONHUMAN; RAT; SEIZURE;

ANIMALIA; RATTUS;

EID: 78650153306     PISSN: 09716580     EISSN: None     Source Type: Journal    
DOI: 10.4103/0971-6580.72682     Document Type: Article

References (26)

1. Jensen KF, Varner JA, Horvath WJ, Isaacson RL. Chronic administration of aluminium-flouride or sodium-fluoride to rats in the drinking water: Alterations in neuronal and cerebrovascular integrity. Brain Res 1998;784:284-98.
2. Suarez-Fernandez MB, Soldado AB, Sanz-Medel A, Vaga JA, Novelli A, Fernandez-Sanchez MT. Aluminium-induced degeneration of astrocytes occurs via apoptosis and results in neuronal death. Brain Res 1999;835:125-36.
3. van der Voet GB, Schijns O, de Wolff FA. Flouride enhances the effect of aluminium chloride on interconnections between aggregates of hippocampal neurons. Arch Physiol Biochem 1999;101:15-21.
4. Morris CM, Candy JM, Oakley AE, Taylor GA, Moutfort S, Bishop H, et al. Comparison of the regional distribution of transferrin receptors in the forebrain of chronic renal dialysis patients. J Neurol Sci 1989;94:295-306. (Pubitemid 20019465)
5. Altmann P, Cunningham J, Dhanasha U, Ballard M, Thompson J. Disturbance of cerebral function in people exposed to drinking water contaminated with aluminium sulphate: Retrospective study of the camelford water incidence. Br Med J 1999;319:807-11.
6. Feldman RS, Meyer JS, Quenzer LF. Principles of Neuropsychopharmacology. Massachusetts, USA: Sinauer Associates; 1997. p. 277-84.
7. Finney DJ. Probit analysis. 2 nd ed. London: Cambridge University Press; 1964.
8. Metcalf RI. In: Glick, editor. Methods of Biochemical analysis. Vol. 5. New York: Interscience Publishers Inc; 1957.
9. Augustinsson KB. In: Glick D, editor. Methods of Biochemical Analysis. Vol. 5 New York: Interscience Publishers; 1957.
10. Ellman GL, Courtney KD, Featherstone RM. A new and rapid colorimetric determination of acetylcholinesterase activity. Biochem Pharmacol 1961;7:88-95.
11. Glowinski J, Iverson II. Regional studies on catecholamines in the rat brain. Neuropharmacol 1966;13:655-69.
12. Jankowska A, Madziar B, Tomaszewicz M, Szutowicz A. Acute and chronic effects of acetyl Co-A and acetylcholine metabolism in differentiated and non differentiated SN 56 cholinergic cells. J Neurosci Res 2000;62:615-22.
13. Zaman K, Zaman W, Siddique H. Haematological and enzymatic results of aluminium intoxication in rats. Comp Biochem 1993;105c:73-6.
14. Haris C, Vassilios T, Antonios S, Apostolosz, Stylianos T. Cadmium effects on brain acetylcholinesterase activity and antioxidant status of adult rats: Modulation by Zinc, Calcium and L-Cystine co-administration. Basic Clin Pharmacol 2005;97:320-4.
15. Ani M, Moshtaghie AA, Aghadavood M. Protective effects of selenium and zinc on the brain acetyl-cholinesterase activity in lead intoxified rat. Res Pharm Sci 2006;2:80-4.
16. Powell JJ, Whitehead MW, Ainley CC, Kendall MD, Nicholson JK, Thompson RP. Dietary minerals in the gastrointestinal tract: Hydroxypolymerisation of aluminium is regulated by luminal mucins. J Inorg Biochem 1999;75:167-80.
17. Kausz AT, Antonsen JE, Hercz G, Pei Y, Weiss NS, Emerson S, et al. Screnning plasma aluminium levels in relation to aluminium bone disease among asymptomatic dialysis patients. Am J Kidney Dis 1999;34:688-93.
18. Cremer JE, Johnston PV, Roots BI, Trevor AJ. Heterogeneity of brain fractions containing neuronal and glial cells. J Neurochem 1968;15:1361-70.
19. Vasishta RK, Gill KD. Distribution of aluminium in different brain regions and body organs of rat. Biol Trace Elem Res 1996;52:181-92.
20. Kandaiah J, Kies C. Aluminium concentrations in tissues of rats: Effect of soft drink packaging. Biometals 1994;7:57-60.
21. Fosbracy P, Wetherell JR, French MC. Neurotransmitter changes in guinea-pig brain regions following soman intoxication. J Neurochem 1990;54:72-9.
22. Hewitt CD, Savory J, Wills MR. Aspects of aluminium toxicity. Clin Lab Med 1990;10:403-22.
23. Vandanplas O, Delwiche JP, Vanbilsen ML, Joly J, Roosels D. Occupational asthma caused by aluminium welding. Eur Respir J 1998;11:1182-4.
24. Heyer NJ. Potroom palsy? Neurologic disorder in three aluminum smelter workers. Arch Intern Med 1985;145:1972-5.
25. Joshi JG. Aluminium, a neurotoxin which affects diverse metabolic reactions. Biofactors 1990;2:163-9.
26. Morley R, Bishop NJ, Day JP, Lucas A. Aluminium neurotoxicity in preterm infants receiving intravenous-feeding solutions. N Engl J Med 1997;336:1557-61.