Pain is a salient "stressor" that is mediated by corticotropin-releasing factor-1 receptors

Neuropharmacology

Volumn 59, Issue 3, 2010, Pages 160-166

  Hummel, Michele ^a   Cummons, Terri ^a   Lu, Peimin ^a   Mark, Lilly ^a   Harrison, James E ^a   Kennedy, Jeffrey D ^a   Whiteside, Garth T ^a  

^a Pfizer Global Research and Development   (United States)

Author keywords

CRF; Inflammation; Pain; Stress

Indexed keywords

5 CHLORO 4 [N (CYCLOPROPYLMETHYL) N PROPYLAMINO] 2 METHYL 6 (2,4,6 TRICHLOROANILINO)PYRIMIDINE; BUTYL[2,5 DIMETHYL 7 (2,4,6 TRIMETHYLPHENYL) 7H PYRROLO[2,3 D]PYRIMIDIN 4 YL]ETHYLAMINE; CARRAGEENAN; CELECOXIB; CORTICOTROPIN RELEASING FACTOR RECEPTOR 1; CP 154 526; INDOMETACIN; MORPHINE; SAPORIN; UNCLASSIFIED DRUG; 2-METHYL-4-(N-PROPYL-N-CYCLOPROANEMETHYLAMINO)-5-CHLORO-6-(2,4,6-TRICHLORANILINO)PYRIMIDINE; ANILINE DERIVATIVE; CORTICOTROPIN RELEASING FACTOR; CORTICOTROPIN RELEASING FACTOR RECEPTOR; NONSTEROID ANTIINFLAMMATORY AGENT; PYRIMIDINE DERIVATIVE; PYRROLE DERIVATIVE;

ALLODYNIA; ANALGESIA; ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG TARGETING; HYPERALGESIA; HYPERSENSITIVITY; INFLAMMATION; MALE; MECHANICAL STIMULATION; NERVE LIGATION; NEUROPATHIC PAIN; NONHUMAN; PAIN; PAIN ASSESSMENT; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN FUNCTION; RAT; REFERRED PAIN; TEMPERATURE SENSITIVITY; TOUCH; ULCER; ANIMAL; ANTAGONISTS AND INHIBITORS; CHEMICALLY INDUCED; COMPLICATION; DISEASE MODEL; DOSE RESPONSE; DRUG ADMINISTRATION; DRUG EFFECTS; DRUG INTERACTION; MENTAL STRESS; METABOLISM; MOUSE; PAIN THRESHOLD; SPINAL CORD INJURY; SPRAGUE DAWLEY RAT; STOMACH ULCER;

ANILINE COMPOUNDS; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CARRAGEENAN; CORTICOTROPIN-RELEASING HORMONE; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ADMINISTRATION SCHEDULE; DRUG INTERACTIONS; HYPERALGESIA; INDOMETHACIN; INFLAMMATION; MALE; MICE; PAIN; PAIN THRESHOLD; PYRIMIDINES; PYRROLES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, CORTICOTROPIN-RELEASING HORMONE; SPINAL CORD INJURIES; STOMACH ULCER; STRESS, PSYCHOLOGICAL;

EID: 77954216390     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2010.05.001     Document Type: Article

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