-
1
-
-
78049485263
-
Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008
-
Ferlay, J.; Shin, H.R.; Bray, F.; Forman, D.; Mathers, C.; Parkin, D.M. Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. Int. J. Cancer 2010, 127, 2893-2917.
-
(2010)
Int. J. Cancer
, vol.127
, pp. 2893-2917
-
-
Ferlay, J.1
Shin, H.R.2
Bray, F.3
Forman, D.4
Mathers, C.5
Parkin, D.M.6
-
2
-
-
0028608838
-
Factors influencing survival of patients after radical surgery for gastric cancer
-
Arak, A.; Kull, K. Factors influencing survival of patients after radical surgery for gastric cancer. Ann. Oncol. 1994, 33, 913-920.
-
(1994)
Ann. Oncol
, vol.33
, pp. 913-920
-
-
Arak, A.1
Kull, K.2
-
3
-
-
33745726677
-
Perioperative chemotherapy versus surgery alone for respectable gastroesophageal cancer
-
Cunningham, D.; Allum, W.H.; Stenning, S.P.; Thompson, J.N.; van de Velde, C.J.; Nicolson, M.; Scarffe, J.H.; Lofts, F.J.; Falk, S.J.; Iveson T.J., et al. Perioperative chemotherapy versus surgery alone for respectable gastroesophageal cancer. N. Engl. J. Med. 2006, 355, 11-20.
-
(2006)
N. Engl. J. Med
, vol.355
, pp. 11-20
-
-
Cunningham, D.1
Allum, W.H.2
Stenning, S.P.3
Thompson, J.N.4
van de Velde, C.J.5
Nicolson, M.6
Scarffe, J.H.7
Lofts, F.J.8
Falk, S.J.9
Iveson, T.J.10
-
4
-
-
47949102120
-
Gastric cancer: Pathogenesis, screening and treatment
-
Sugano, K. Gastric cancer: Pathogenesis, screening and treatment. Gastrointest. Endosc. Clin. N. Am. 2008, 18, 513-522.
-
(2008)
Gastrointest. Endosc. Clin. N. Am
, vol.18
, pp. 513-522
-
-
Sugano, K.1
-
5
-
-
0035818048
-
Chemoradiotherapy after surgery compared with surgery alone for adenocarcinoma of the stomach or gastroesophageal junction
-
Macdonald, J.S.; Smalley, S.R.; Benedetti, J.; Hundahl, S.A.; Estes, N.C.; Stemmermann, G.N.; Haller, D.G.; Ajani, J.A.; Gunderson, L.L.; Jessup J.M. et al. Chemoradiotherapy after surgery compared with surgery alone for adenocarcinoma of the stomach or gastroesophageal junction. N. Engl. J. Med. 2001, 345, 725-730.
-
(2001)
N. Engl. J. Med
, vol.345
, pp. 725-730
-
-
Macdonald, J.S.1
Smalley, S.R.2
Benedetti, J.3
Hundahl, S.A.4
Estes, N.C.5
Stemmermann, G.N.6
Haller, D.G.7
Ajani, J.A.8
Gunderson, L.L.9
Jessup, J.M.10
-
6
-
-
38049047178
-
Capecitabine and Oxaliplatin for Advanced Esophagogastric Cancer
-
Cunningham, D.; Starling, N.; Rao, S.; Iveson, T.; Nicolson, M.; Coxon, F.; Middleton, G.; Daniel, F.; Oates, J.; Norman, A.R. Capecitabine and Oxaliplatin for Advanced Esophagogastric Cancer. N. Engl. J. Med. 2008, 358, 36-46.
-
(2008)
N. Engl. J. Med
, vol.358
, pp. 36-46
-
-
Cunningham, D.1
Starling, N.2
Rao, S.3
Iveson, T.4
Nicolson, M.5
Coxon, F.6
Middleton, G.7
Daniel, F.8
Oates, J.9
Norman, A.R.10
-
7
-
-
33745547767
-
Chemotherapy in advanced gastric cancer: A systematic review and meta-analysis based on aggregate data
-
Wagner, A.D.; Grothe, W.; Haerting, J.; Kleber, G.; Grothey, A.; Fleig, W.E. Chemotherapy in advanced gastric cancer: A systematic review and meta-analysis based on aggregate data. J. Clin. Oncol. 2006, 24, 2903-2909.
-
(2006)
J. Clin. Oncol
, vol.24
, pp. 2903-2909
-
-
Wagner, A.D.1
Grothe, W.2
Haerting, J.3
Kleber, G.4
Grothey, A.5
Fleig, W.E.6
-
8
-
-
77956262693
-
T in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastro-oesophageal junction cancer (ToGA): A phase 3, open-label, randomised controlled trial
-
Bang, Y.J.; van Cutsem, E.; Feyereislova, A.; Chung, H.C.; Shen, L.; Sawaki, A.; Lordick, F.; Ohtsu, A.; Omuro, Y.; Satoh, T, et al. T in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastro-oesophageal junction cancer (ToGA): A phase 3, open-label, randomised controlled trial. Lancet 2010, 376, 687-697.
-
(2010)
Lancet
, vol.376
, pp. 687-697
-
-
Bang, Y.J.1
van Cutsem, E.2
Feyereislova, A.3
Chung, H.C.4
Shen, L.5
Sawaki, A.6
Lordick, F.7
Ohtsu, A.8
Omuro, Y.9
Satoh, T.10
-
9
-
-
0025321157
-
Epidermal growth factor
-
Carpenter, G.; Cohen, S. Epidermal growth factor. J. Biol. Chem. 1990, 265, 7709-7712.
-
(1990)
J. Biol. Chem
, vol.265
, pp. 7709-7712
-
-
Carpenter, G.1
Cohen, S.2
-
10
-
-
2342492317
-
Review of epidermal growth factor receptor biology
-
Herbst, R.S. Review of epidermal growth factor receptor biology. Int. J. Radiat. Oncol. Biol. Phys. 2004, 59, 21-26.
-
(2004)
Int. J. Radiat. Oncol. Biol. Phys
, vol.59
, pp. 21-26
-
-
Herbst, R.S.1
-
11
-
-
33746889808
-
A comprehensive pathway map of epidermal growth factor receptor signaling
-
Oda, K.; Matsuoka, Y.; Funahashi, A.; Kitano, H. A comprehensive pathway map of epidermal growth factor receptor signaling. Mol. Syst. Biol. 2005, 1, 1-17.
-
(2005)
Mol. Syst. Biol
, vol.1
, pp. 1-17
-
-
Oda, K.1
Matsuoka, Y.2
Funahashi, A.3
Kitano, H.4
-
12
-
-
0032463525
-
Role of the 6-20 disulfide bridge in the structure and activity of epidermal growth factor
-
Barnham, K.J.; Torres, A.M.; Alewood, D.; Alewood, P.F.; Domagala, T.; Nice, E.C.; Norton, R.S. Role of the 6-20 disulfide bridge in the structure and activity of epidermal growth factor. Protein Sci. 1998, 7, 1738-1749.
-
(1998)
Protein Sci
, vol.7
, pp. 1738-1749
-
-
Barnham, K.J.1
Torres, A.M.2
Alewood, D.3
Alewood, P.F.4
Domagala, T.5
Nice, E.C.6
Norton, R.S.7
-
13
-
-
0012060744
-
Characterization of epidermal growth factor (EGF) receptor and transforming growth factor (TGF) alpha expression in gastric cancer and its association with activation of mitogen-activated protein kinase (MAPK)
-
Abstract 1717
-
Rojo, F.; Albanell, J.; Sauleda, S.; Baselga, J. Characterization of epidermal growth factor (EGF) receptor and transforming growth factor (TGF) alpha expression in gastric cancer and its association with activation of mitogen-activated protein kinase (MAPK). Proc. Am. Soc. Clin. Oncol. 2001; 20 Abstract 1717
-
(2001)
Proc. Am. Soc. Clin. Oncol
, pp. 20
-
-
Rojo, F.1
Albanell, J.2
Sauleda, S.3
Baselga, J.4
-
14
-
-
3042767348
-
Epidermal growth factor receptor expression correlates with poor survival in gastric adenocarcinoma from Mexican patients: A multivariate analysis using a standardized immunohistochemical detection system
-
Gamboa-Dominguez, A.; Dominguez-Fonseca, C.; Quintanilla-Martinez, L.; Reyes-Gutierrez, E.; Green, D.; Angeles-Angeles, A.; Busch, R.; Hermannstädter, C.; Nährig, J.; Becker, K.F., et al. Epidermal growth factor receptor expression correlates with poor survival in gastric adenocarcinoma from Mexican patients: A multivariate analysis using a standardized immunohistochemical detection system. Mod. Pathol. 2004, 17, 579-584.
-
(2004)
Mod. Pathol
, vol.17
, pp. 579-584
-
-
Gamboa-Dominguez, A.1
Dominguez-Fonseca, C.2
Quintanilla-Martinez, L.3
Reyes-Gutierrez, E.4
Green, D.5
Angeles-Angeles, A.6
Busch, R.7
Hermannstädter, C.8
Nährig, J.9
Becker, K.F.10
-
15
-
-
33846928248
-
Expression of epidermal growth factor receptor in esophageal and esophagogastric junction adenocarcinomas: Association with poor outcome
-
Wang, K.L.; Wu, T.T.; Choi, I.S.; Wang, H.; Resetkova, E.; Correa, A.M.; Hofstetter, W.L.; Swisher, S.G.; Ajani, J.A.; Rashid, A., et al. Expression of epidermal growth factor receptor in esophageal and esophagogastric junction adenocarcinomas: Association with poor outcome. Cancer 2007, 109, 658-667.
-
(2007)
Cancer
, vol.109
, pp. 658-667
-
-
Wang, K.L.1
Wu, T.T.2
Choi, I.S.3
Wang, H.4
Resetkova, E.5
Correa, A.M.6
Hofstetter, W.L.7
Swisher, S.G.8
Ajani, J.A.9
Rashid, A.10
-
16
-
-
55949117201
-
The growth inhibitory effect of lapatinib, a dual inhibitor of EGFR and HER2 tyrosine kinase, in gastric cancer cell lines
-
Kim, J.W.; Kim, H.P.; Im, S.A.; Kang, S.; Hur, H.S.; Yoon, Y.K.; Oh, D.Y.; Kim, J.H.; Lee, D.S.; Kim, T.Y., et al. The growth inhibitory effect of lapatinib, a dual inhibitor of EGFR and HER2 tyrosine kinase, in gastric cancer cell lines. Cancer Lett. 2008, 272, 296-306.
-
(2008)
Cancer Lett
, vol.272
, pp. 296-306
-
-
Kim, J.W.1
Kim, H.P.2
Im, S.A.3
Kang, S.4
Hur, H.S.5
Yoon, Y.K.6
Oh, D.Y.7
Kim, J.H.8
Lee, D.S.9
Kim, T.Y.10
-
17
-
-
34250630933
-
Epidermal growth factor receptor (EGFR) expression is associated with a worse prognosis in gastric cancer patients undergoing curative surgery
-
Galizia, G.; Lieto, E.; Orditura, M.; Castellano, P.; Mura, A.L.; Imperatore, V.; Pinto, M.; Zamboli, A.; de Vita, F.; Ferraraccio, F. Epidermal growth factor receptor (EGFR) expression is associated with a worse prognosis in gastric cancer patients undergoing curative surgery. World J. Surg. 2007, 31, 1458-1468.
-
(2007)
World J. Surg
, vol.31
, pp. 1458-1468
-
-
Galizia, G.1
Lieto, E.2
Orditura, M.3
Castellano, P.4
Mura, A.L.5
Imperatore, V.6
Pinto, M.7
Zamboli, A.8
de Vita, F.9
Ferraraccio, F.10
-
18
-
-
38049177080
-
Expression of vascular endothelial growth factor (VEGF) and epidermal growth factor receptor (EGFR) is an independent prognostic indicator of worse outcome in gastric cancer patients
-
Lieto, E.; Ferraraccio, F.; Orditura, M.; Castellano, P.; Mura, A.L.; Pinto, M.; Zamboli, A.; de Vita, F.; Galizia, G. Expression of vascular endothelial growth factor (VEGF) and epidermal growth factor receptor (EGFR) is an independent prognostic indicator of worse outcome in gastric cancer patients. Ann. Surg. Oncol. 2008, 15, 69-79.
-
(2008)
Ann. Surg. Oncol
, vol.15
, pp. 69-79
-
-
Lieto, E.1
Ferraraccio, F.2
Orditura, M.3
Castellano, P.4
Mura, A.L.5
Pinto, M.6
Zamboli, A.7
de Vita, F.8
Galizia, G.9
-
19
-
-
69949127786
-
Anti-epidermal growth factor receptor monoclonal antibodies in cancer therapy
-
Martinelli, E.; de Palma, R.; Orditura, M.; de Vita, F.; Ciardiello, F. Anti-epidermal growth factor receptor monoclonal antibodies in cancer therapy. Clin. Exp. Immunol. 2009, 158, 1-9.
-
(2009)
Clin. Exp. Immunol
, vol.158
, pp. 1-9
-
-
Martinelli, E.1
de Palma, R.2
Orditura, M.3
de Vita, F.4
Ciardiello, F.5
-
20
-
-
33847663871
-
Phase II study of cetuximab in combination with FOLFIRI in patients with untreated advanced gastric or gastroesophageal junction adenocarcinoma (FOLCETUX study)
-
Pinto, C.; di Fabio, F.; Siena, S.; Cascinu, S.; Rojas Llimpe, F.L.; Ceccarelli, C.; Mutri, V.; Giannetta, L.; Giaquinta, S.; Funaioli, C., et al. Phase II study of cetuximab in combination with FOLFIRI in patients with untreated advanced gastric or gastroesophageal junction adenocarcinoma (FOLCETUX study). Ann. Oncol. 2007, 18, 510-517.
-
(2007)
Ann. Oncol
, vol.18
, pp. 510-517
-
-
Pinto, C.1
di Fabio, F.2
Siena, S.3
Cascinu, S.4
Rojas, L.F.L.5
Ceccarelli, C.6
Mutri, V.7
Giannetta, L.8
Giaquinta, S.9
Funaioli, C.10
-
21
-
-
70349937924
-
Phase II of cetuximab in combination with cis/docetaxel as first-line treatment in patients with unresectable/metastatic gastric or gastroesophageal junction (GEJ) adenocarcinoma (DOCETUX study)
-
Pinto, C.; di Fabio, F.; Barone, C.; Siena, S.; Falcone, A.; Cascinu, S.; Rojas-Llimpe, F.L.; Stella, G.; Schinzari, G.; Artale, S., et al. Phase II of cetuximab in combination with cis/docetaxel as first-line treatment in patients with unresectable/metastatic gastric or gastroesophageal junction (GEJ) adenocarcinoma (DOCETUX study). Br. J. Cancer 2009, 101, 1261-1268.
-
(2009)
Br. J. Cancer
, vol.101
, pp. 1261-1268
-
-
Pinto, C.1
di Fabio, F.2
Barone, C.3
Siena, S.4
Falcone, A.5
Cascinu, S.6
Rojas-Llimpe, F.L.7
Stella, G.8
Schinzari, G.9
Artale, S.10
-
22
-
-
58749089260
-
Phase II study and biomarker analysis of cetuximab in combination with modified FOLFOX6 in advanced gastric cancer
-
Han, S.W.; Oh, D.Y.; Im, S.A.; Park, S.R.; Lee, K.W.; Song, H.S.; Lee, N.S.; Lee, K.H.; Choi, I.S.; Lee, M.H., et al. Phase II study and biomarker analysis of cetuximab in combination with modified FOLFOX6 in advanced gastric cancer. Br. J. Cancer 2009, 100, 298-304.
-
(2009)
Br. J. Cancer
, vol.100
, pp. 298-304
-
-
Han, S.W.1
Oh, D.Y.2
Im, S.A.3
Park, S.R.4
Lee, K.W.5
Song, H.S.6
Lee, N.S.7
Lee, K.H.8
Choi, I.S.9
Lee, M.H.10
-
23
-
-
79957539777
-
A prospective phase II study of cetuximab in combination with XELOX (capecitabine and oxaliplatin) in patients with metastatic and/or recurrent advanced gastric cancer
-
Kim, C.; Lee, J.L.; Ryu, M.H.; Chang, H.M.; Kim, T.W.; Lim, H.Y.; Kang, H.J.; Park, Y.S.; Ryoo, B.Y.; Kang, Y.K. A prospective phase II study of cetuximab in combination with XELOX (capecitabine and oxaliplatin) in patients with metastatic and/or recurrent advanced gastric cancer. Invest. New Drugs 2011, 29, 366-373.
-
(2011)
Invest. New Drugs
, vol.29
, pp. 366-373
-
-
Kim, C.1
Lee, J.L.2
Ryu, M.H.3
Chang, H.M.4
Kim, T.W.5
Lim, H.Y.6
Kang, H.J.7
Park, Y.S.8
Ryoo, B.Y.9
Kang, Y.K.10
-
24
-
-
72349084837
-
Cetuximab with irinotecan/folinic acid/5-FU as first line treatment in advanced gastric cancer: A nonrandomized multicenter AIO phase II study
-
Abstract 4534
-
Kanzler, S.; Trarbach, T.; Seufferlein, T.; Kubicka, S.; Lordick, F.; Geissler, M.; Daum, S.; Galle, P.R.; Moehler, M. Cetuximab with irinotecan/folinic acid/5-FU as first line treatment in advanced gastric cancer: A nonrandomized multicenter AIO phase II study. J. Clin. Oncol. 2009, 27, Abstract 4534.
-
(2009)
J. Clin. Oncol
, vol.27
-
-
Kanzler, S.1
Trarbach, T.2
Seufferlein, T.3
Kubicka, S.4
Lordick, F.5
Geissler, M.6
Daum, S.7
Galle, P.R.8
Moehler, M.9
-
25
-
-
72349094937
-
Phase II study of cetuximab plus weekly cis and 24-h infusion of high-dose 5-fluorouracil and leucovorin for the first-line treatment of advanced gastric cancer
-
Abstract 4567
-
Yeh, K.; Hsu, C.; Hsu, C.; Lin, C.; Shen, Y.; Wu, S.; Chiou, T.; Chao, Y.; Cheng, A. Phase II study of cetuximab plus weekly cis and 24-h infusion of high-dose 5-fluorouracil and leucovorin for the first-line treatment of advanced gastric cancer. J. Clin. Oncol. 2009, 27, Abstract 4567.
-
(2009)
J. Clin. Oncol
, vol.27
-
-
Yeh, K.1
Hsu, C.2
Hsu, C.3
Lin, C.4
Shen, Y.5
Wu, S.6
Chiou, T.7
Chao, Y.8
Cheng, A.9
-
26
-
-
84875238657
-
A phase II study of cetuximab with cis and capecitabine as first-line treatment in advanced gastric cancer
-
Abstract 15663
-
Zhang, X.; Xu, J.; Shen, L.; Wang, J.; Liang, J.; Xu, N.; Bai, Y.; Wang, J. A phase II study of cetuximab with cis and capecitabine as first-line treatment in advanced gastric cancer. J. Clin. Oncol. 2008, 26, Abstract 15663.
-
(2008)
J. Clin. Oncol
, pp. 26
-
-
Zhang, X.1
Xu, J.2
Shen, L.3
Wang, J.4
Liang, J.5
Xu, N.6
Bai, Y.7
Wang, J.8
-
27
-
-
67349281373
-
Oxaliplatin, iri, and cetuximab in advanced gastric cancer. First efficacy results of a multicenter phase II trial of the AGMT
-
Abstract 15587
-
Wöll, E.; Greil, R.; Eisterer, W.; Fridrik, M.; Grünberger, B.; Gattringer, K.; Mayrbäurl, B.; Russ, G.; Thaler, J. Oxaliplatin, iri, and cetuximab in advanced gastric cancer. First efficacy results of a multicenter phase II trial of the AGMT. J. Clin. Oncol. 2008, 26, Abstract 15587.
-
(2008)
J. Clin. Oncol
, vol.26
-
-
Wöll, E.1
Greil, R.2
Eisterer, W.3
Fridrik, M.4
Grünberger, B.5
Gattringer, K.6
Mayrbäurl, B.7
Russ, G.8
Thaler, J.9
-
28
-
-
79961024637
-
Targeting the human EGFR family in esophagogastric cancer
-
Okines, A.; Cunningham, D.; Chau, I. Targeting the human EGFR family in esophagogastric cancer. Nat. Rev. Clin. Oncol. 2011, 8, 492-503.
-
(2011)
Nat. Rev. Clin. Oncol
, vol.8
, pp. 492-503
-
-
Okines, A.1
Cunningham, D.2
Chau, I.3
-
29
-
-
84855958099
-
Advanced gastric cancer (GC) and cancer of the gastro-oesophageal junction (GEJ): Focus on targeted therapies
-
Cappetta, A.; Lonardi, S.; Pastorelli, D.; Bergamo, F.; Lombardi, G.; Zagonel, V. Advanced gastric cancer (GC) and cancer of the gastro-oesophageal junction (GEJ): Focus on targeted therapies. Crit. Rev. Oncol. Hematol. 2012, 81, 38-48.
-
(2012)
Crit. Rev. Oncol. Hematol
, vol.81
, pp. 38-48
-
-
Cappetta, A.1
Lonardi, S.2
Pastorelli, D.3
Bergamo, F.4
Lombardi, G.5
Zagonel, V.6
-
30
-
-
79951532484
-
CALGB 80403/ECOG 1206: A randomized phase II study of three standard chemotherapy regimens (ECF, IC, FOLFOX) plus cetuximab in metastatic esophageal and GE junction cancer
-
Abstract 4006
-
Enzinger, P.C.; Burtness, B.; Hollis, D.; Niedzwiecki, D.; Ilson, D.; Benson, A.B.; Mayer, R.J.; Goldberg, M. CALGB 80403/ECOG 1206: A randomized phase II study of three standard chemotherapy regimens (ECF, IC, FOLFOX) plus cetuximab in metastatic esophageal and GE junction cancer. J. Clin. Oncol. 2010, 28, Abstract 4006
-
(2010)
J. Clin. Oncol
, vol.28
-
-
Enzinger, P.C.1
Burtness, B.2
Hollis, D.3
Niedzwiecki, D.4
Ilson, D.5
Benson, A.B.6
Mayer, R.J.7
Goldberg, M.8
-
31
-
-
84875255256
-
-
Available online:, (accessed on 5 July 2012)
-
Leach, B. Cetuximab Fails to Extend PFS in Advanced Gastric Cancer. Available online: http://www.onclive.com/web-exclusives/Cetuximab-Fails-to-Extend-PFS-in-Advanced-Gastric-Cancer/ (accessed on 5 July 2012)
-
Cetuximab Fails to Extend PFS In Advanced Gastric Cancer
-
-
Leach, B.1
-
32
-
-
38149088836
-
Cetuximab with concurrent chemoradiation for esophagogastric cancer: Assessment of toxicity
-
Safran, H.; Suntharalingam, M.; Dipetrillo, T.; Ng T.; Doyle, L.A.; Krasna, M.; Plette, A.; Evans, D.; Wanebo, H.; Akerman, P., et al. Cetuximab with concurrent chemoradiation for esophagogastric cancer: Assessment of toxicity. Int. J. Radiat. Oncol. Biol. Phys. 2008, 70, 391-395.
-
(2008)
Int. J. Radiat. Oncol. Biol. Phys
, vol.70
, pp. 391-395
-
-
Safran, H.1
Suntharalingam, M.2
Dipetrillo, T.3
Ng, T.4
Doyle, L.A.5
Krasna, M.6
Plette, A.7
Evans, D.8
Wanebo, H.9
Akerman, P.10
-
33
-
-
79957834501
-
A multicenter phase II trial of single-agent cetuximab in advanced esophageal and gastric adenocarcinoma
-
Chan, J.A.; Blaszkowsky, L.S.; Enzinger, P.C.; Ryan, D.P.; Abrams, T.A.; Zhu, A.X.; Temel, J.S.; Schrag, D.; Bhargava, P.; Meyerhardt, J.A. et al. A multicenter phase II trial of single-agent cetuximab in advanced esophageal and gastric adenocarcinoma. Ann. Oncol. 2011, 22, 1367-1373.
-
(2011)
Ann. Oncol
, vol.22
, pp. 1367-1373
-
-
Chan, J.A.1
Blaszkowsky, L.S.2
Enzinger, P.C.3
Ryan, D.P.4
Abrams, T.A.5
Zhu, A.X.6
Temel, J.S.7
Schrag, D.8
Bhargava, P.9
Meyerhardt, J.A.10
-
34
-
-
77956267602
-
Cetuximab as second-line therapy in patients with metastatic esophageal adenocarcinoma: A phase II Southwest Oncology Group Study (S0415)
-
Gold, P.J.; Goldman, B.; Iqbal, S.; Leichman, L.P.; Zhang, W.; Lenz, H.J.; Blanke, C.D. Cetuximab as second-line therapy in patients with metastatic esophageal adenocarcinoma: A phase II Southwest Oncology Group Study (S0415). J. Thorac. Oncol. 2010, 5, 1472-1476.
-
(2010)
J. Thorac. Oncol
, vol.5
, pp. 1472-1476
-
-
Gold, P.J.1
Goldman, B.2
Iqbal, S.3
Leichman, L.P.4
Zhang, W.5
Lenz, H.J.6
Blanke, C.D.7
-
35
-
-
67349122733
-
ATTAX2: Docetaxel plus cetuximab as second-line treatment for docetaxel-refractory oesophago-gastric cancer-final results of a multicentre phase II trial by the AGITG
-
Abstract 15554
-
Tebbutt, N.C.; Sourjina, T.; Strickland, A.H.; van Hazel, G.A.; Pavlakis, N.; Ganju, V.; Murone, C.; MacGregor, D.; Gebski, V.; Cummins, M. ATTAX2: Docetaxel plus cetuximab as second-line treatment for docetaxel-refractory oesophago-gastric cancer-final results of a multicentre phase II trial by the AGITG. J. Clin. Oncol. 2008, 26, Abstract 15554.
-
(2008)
J. Clin. Oncol
, vol.26
-
-
Tebbutt, N.C.1
Sourjina, T.2
Strickland, A.H.3
van Hazel, G.A.4
Pavlakis, N.5
Ganju, V.6
Murone, C.7
Macgregor, D.8
Gebski, V.9
Cummins, M.10
-
36
-
-
80053928673
-
Cetuximab with irinotecan as salvage therapy in heavily pretreated patients with metastatic gastric cancer
-
Abstract 47
-
Stein, A.; Al-Batran, S.E.; Arnold, D.; Peinert, S.; Siewczynski, R.; Schmoll, H.J. Cetuximab with irinotecan as salvage therapy in heavily pretreated patients with metastatic gastric cancer. J. Clin. Oncol. 2007, Abstract 47.
-
(2007)
J. Clin. Oncol
-
-
Stein, A.1
Al-Batran, S.E.2
Arnold, D.3
Peinert, S.4
Siewczynski, R.5
Schmoll, H.J.6
-
37
-
-
84875272842
-
A phase III trial of iri in patients with advanced adenocarcinoma of the gastroesophageal junction
-
Abstract 1130
-
Lin, L.; Hecht, J. A phase III trial of iri in patients with advanced adenocarcinoma of the gastroesophageal junction. J. Clin. Oncol. 2000, 19, Abstract 1130.
-
(2000)
J. Clin. Oncol
, vol.19
-
-
Lin, L.1
Hecht, J.A.2
-
38
-
-
77951983624
-
Irinotecan versus best supportive care (BSC) as second-line therapy in gastric cancer: A randomized phase III study of the Arbeitsgemeinschaft Internistische Onkologie (AIO)
-
Abstract 4540
-
Thuss-Patience, P.C.; Kretzschmar, A.; Deist, T.; Hinke, A.; Bichev, D.; Lebedinzew, B.; Schumacher, G.; Gebauer, B.; Maier, V.; Reichardt, P. Irinotecan versus best supportive care (BSC) as second-line therapy in gastric cancer: A randomized phase III study of the Arbeitsgemeinschaft Internistische Onkologie (AIO). Proc. Am. Soc. Clin. Oncol. 2009, 27, Abstract 4540
-
(2009)
Proc. Am. Soc. Clin. Oncol
, vol.27
-
-
Thuss-Patience, P.C.1
Kretzschmar, A.2
Deist, T.3
Hinke, A.4
Bichev, D.5
Lebedinzew, B.6
Schumacher, G.7
Gebauer, B.8
Maier, V.9
Reichardt, P.10
-
39
-
-
34248372373
-
Rationale and clinical results of multi-target treatments in oncology
-
Sartore-Bianchi, A.; Ricotta, R.; Cerea, G.; Maugeri, M.R.; Siena, S. Rationale and clinical results of multi-target treatments in oncology. Int. J. Biol. Markers. 2007, 22, S77-S87
-
(2007)
Int. J. Biol. Markers
, vol.22
-
-
Sartore-Bianchi, A.1
Ricotta, R.2
Cerea, G.3
Maugeri, M.R.4
Siena, S.5
-
40
-
-
77957552916
-
Epirubicin oxaliplatin, and capecitabine with or without panitumumab for advanced esophagogastric cancer: Dose-finding study for the prospective multicenter, randomized, Phase II/III REAL-3 Trial
-
Okines, A.F.; Ashley, S.E.; Cunningham, D.; Oates, J.; Turner, A.; Webb, J.; Saffery, C., Chua, Y.J.; Chau, I. Epirubicin, oxaliplatin, and capecitabine with or without panitumumab for advanced esophagogastric cancer: Dose-finding study for the prospective multicenter, randomized, Phase II/III REAL-3 Trial. J. Clin. Oncol. 2010, 28, 3945-3950.
-
(2010)
J. Clin. Oncol
, vol.28
, pp. 3945-3950
-
-
Okines, A.F.1
Ashley, S.E.2
Cunningham, D.3
Oates, J.4
Turner, A.5
Webb, J.6
Saffery, C.7
Chua, Y.J.8
Chau, I.9
-
41
-
-
82655169014
-
REAL3: A multicenter randomized phase II/III trial of epirubicin, oxaliplatin, and capecitabine (EOC) versus modified (m) EOC plus panitumumab (P) in advanced oesophagogastric (OG) cancer. Response rate (RR), toxicity, and molecular analysis from phase II
-
Abstract 4131
-
Chau, I.; Okines, A.F.C.; González de Castro, D.; Saffery, C.; Barbachano, Y.; Wotherspoon, L.; Puckey, L.; Hulkki Wilson, S.; Coxon, F.Y.; Middleton G.W, et al. REAL3: A multicenter randomized phase II/III trial of epirubicin, oxaliplatin, and capecitabine (EOC) versus modified (m) EOC plus panitumumab (P) in advanced oesophagogastric (OG) cancer. Response rate (RR), toxicity, and molecular analysis from phase II. J. Clin. Oncol. 2011, 29, Abstract 4131.
-
(2011)
J. Clin. Oncol
, vol.29
-
-
Chau, I.1
Okines, A.F.C.2
de González, C.D.3
Saffery, C.4
Barbachano, Y.5
Wotherspoon, L.6
Puckey, L.7
Hulkki, W.S.8
Coxon, F.Y.9
Middleton, G.W.10
-
42
-
-
84868295867
-
A randomized multicenter trial of epirubicin, oxaliplatin, and capecitabine (EOC) plus panitumumab in advanced esophagogastric cancer (REAL3)
-
Abstract 4000
-
Waddell, T.S.; Chau, I.; Barbachano, Y.; González de Castro, D.; Wotherspoon, A.; Saffery, C; Middleton, G.W.; Wadsley, J.; Ferry, D.R.; Mansoor, W, et al. A randomized multicenter trial of epirubicin, oxaliplatin, and capecitabine (EOC) plus panitumumab in advanced esophagogastric cancer (REAL3). J. Clin. Oncol. 2012, 30, Abstract 4000.
-
(2012)
J. Clin. Oncol
, vol.30
-
-
Waddell, T.S.1
Chau, I.2
Barbachano, Y.3
de González, C.D.4
Wotherspoon, A.5
Saffery, C.6
Middleton, G.W.7
Wadsley, J.8
Ferry, D.R.9
Mansoor, W.10
-
43
-
-
79955425807
-
Randomized phase II study of nimotuzumab, an anti-EGFR antibody, plus iri In patients with 5-fluorouracil-based regimen-refractory advanced or recurrent gastric cancer in Korea and Japan: Preliminary results
-
Abstract 87
-
Kim, Y.H.; Sasaki, Y.; Lee, K.H.; Rha, S.Y.; Park, S.; Boku, N.; Komatsu, Y.; Kim, T.; Kim, S.; Sakata, Y. Randomized phase II study of nimotuzumab, an anti-EGFR antibody, plus iri In patients with 5-fluorouracil-based regimen-refractory advanced or recurrent gastric cancer in Korea and Japan: Preliminary results. J. Clin. Oncol. 2011, 29, Abstract 87
-
(2011)
J. Clin. Oncol
, vol.29
-
-
Kim, Y.H.1
Sasaki, Y.2
Lee, K.H.3
Rha, S.Y.4
Park, S.5
Boku, N.6
Komatsu, Y.7
Kim, T.8
Kim, S.9
Sakata, Y.10
-
44
-
-
84875276827
-
Randomized, single-centered, phase II clinical trial of nimotuzumab plus cis and S-1 as first-line therapy in patients with advanced gastric cancer
-
Wang, J.W.; Chi, Y.; Zheng, Z.; Qu, T.; Zhou, A.; Yang, L.; Jiang, W.; Shi, S.; Sun, Y.; Song, Y.; Kang, S. Randomized, single-centered, phase II clinical trial of nimotuzumab plus cis and S-1 as first-line therapy in patients with advanced gastric cancer. J. Clin. Oncol. 2012, 30, e14668
-
(2012)
J. Clin. Oncol
, vol.30
-
-
Wang, J.W.1
Chi, Y.2
Zheng, Z.3
Qu, T.4
Zhou, A.5
Yang, L.6
Jiang, W.7
Shi, S.8
Sun, Y.9
Song, Y.10
Kang, S.11
-
45
-
-
51449124276
-
Phase I study of epirubicin, cis and capecitabin plus matuzumab in previously untreated patients with advanced oesophagogastric cancer
-
Rao, S.; Starling, N.; Cunningham, D.; Benson, M.; Wotherspoon, A.; Lüpfert, C.; Kurek, R.; Oates, J.; Baselga, J.; Hill, A. Phase I study of epirubicin, cis and capecitabin plus matuzumab in previously untreated patients with advanced oesophagogastric cancer. Br. J. Cancer 2008, 99, 868-874.
-
(2008)
Br. J. Cancer
, vol.99
, pp. 868-874
-
-
Rao, S.1
Starling, N.2
Cunningham, D.3
Benson, M.4
Wotherspoon, A.5
Lüpfert, C.6
Kurek, R.7
Oates, J.8
Baselga, J.9
Hill, A.10
-
46
-
-
38049047178
-
Capecitabine and oxaliplatin for advanced esophagogastric cancer
-
Cunningham, D.; Starling, N.; Rao, S.; Iveson, T.; Nicolson, M.; Coxon, F.; Middleton, G.; Daniel, F.; Oates, J.; Norman, A.R. Capecitabine and oxaliplatin for advanced esophagogastric cancer. N. Engl. J. Med. 2008, 358, 36-46.
-
(2008)
N. Engl. J. Med
, vol.358
, pp. 36-46
-
-
Cunningham, D.1
Starling, N.2
Rao, S.3
Iveson, T.4
Nicolson, M.5
Coxon, F.6
Middleton, G.7
Daniel, F.8
Oates, J.9
Norman, A.R.10
-
47
-
-
77958496605
-
Matuzumab plus epirubicin, cis and capecitabine (ECX) compared with epirubicin, cis and capecitabine alone as first-line treatment in patients with advanced oesophago-gastric cancer: A randomised, multicentre open-label phase II study
-
Rao, S.; Starling, N.; Cunningham, D.; Sumpter, K.; Gilligan, D.; Ruhstaller, T.; Valladares-Ayerbes, M.; Wilke, H.; Archer, C.; Kurek, R., et al. Matuzumab plus epirubicin, cis and capecitabine (ECX) compared with epirubicin, cis and capecitabine alone as first-line treatment in patients with advanced oesophago-gastric cancer: A randomised, multicentre open-label phase II study. Ann. Oncol. 2010, 21, 2213-2219.
-
(2010)
Ann. Oncol
, vol.21
, pp. 2213-2219
-
-
Rao, S.1
Starling, N.2
Cunningham, D.3
Sumpter, K.4
Gilligan, D.5
Ruhstaller, T.6
Valladares-Ayerbes, M.7
Wilke, H.8
Archer, C.9
Kurek, R.10
-
48
-
-
10344239413
-
Anovel targeted approach to treating cancer
-
Herbst, R.S.; Fukuoka, M.; Baselga, J. Anovel targeted approach to treating cancer. Nat. Rev. Cancer 2004, 4, 956-965.
-
(2004)
Nat Rev. Cancer
, vol.4
, pp. 956-965
-
-
Herbst, R.S.1
Fukuoka, M.2
Baselga, J.3
-
49
-
-
33748987894
-
Pharmacodynamic studies of gefitinib in tumor biopsy specimens from patients with advanced gastric carcinoma
-
Rojo, F.; Tabernero, J.; Albanell, J.; van Cutsem, E.; Ohtsu, A.; Doi, T.; Koizumi, W.; Shirao, K.; Takiuchi, H.; Ramon y Cajal, S., et al. Pharmacodynamic studies of gefitinib in tumor biopsy specimens from patients with advanced gastric carcinoma. J. Clin. Oncol. 2006, 24, 4309-4316.
-
(2006)
J. Clin. Oncol
, vol.24
, pp. 4309-4316
-
-
Rojo, F.1
Tabernero, J.2
Albanell, J.3
van Cutsem, E.4
Ohtsu, A.5
Doi, T.6
Koizumi, W.7
Shirao, K.8
Takiuchi, H.9
Ramon10
Cajal, S.11
-
50
-
-
77649085714
-
A phase II study of peri-operative concurrent chemotherapy, gefitinib, and hyperfractionated radiation followed by maintenance gefitinib in locoregionally advanced esophagus and gastroesophageal junction cancer
-
Rodriguez, C.P.; Adelstein, D.J.; Rice, T.W.; Rybicki, L.A.; Videtic, G.M.; Saxton, J.P.; Murthy, S.C.; Mason, D.P.; Ives, D.I. A phase II study of peri-operative concurrent chemotherapy, gefitinib, and hyperfractionated radiation followed by maintenance gefitinib in locoregionally advanced esophagus and gastroesophageal junction cancer. J. Thorac. Oncol. 2010, 5, 229-235.
-
(2010)
J. Thorac. Oncol
, vol.5
, pp. 229-235
-
-
Rodriguez, C.P.1
Adelstein, D.J.2
Rice, T.W.3
Rybicki, L.A.4
Videtic, G.M.5
Saxton, J.P.6
Murthy, S.C.7
Mason, D.P.8
Ives, D.I.9
-
51
-
-
33750618860
-
Phase II trial of erlotinib in gastroesophageal junction and gastric adenocarcinomas: SWOG 0127
-
Dragovich, T.; McCoy, S.; Fenoglio-Preiser, C.M.; Wang, J.; Benedetti, J.K.; Baker, A.F.; Hackett, C.B.; Urba, S.G.; Zaner, K.S.; Blanke, C.D., et al. Phase II trial of erlotinib in gastroesophageal junction and gastric adenocarcinomas: SWOG 0127. J. Clin. Oncol. 2006, 24, 4922-4927.
-
(2006)
J. Clin. Oncol
, vol.24
, pp. 4922-4927
-
-
Dragovich, T.1
McCoy, S.2
Fenoglio-Preiser, C.M.3
Wang, J.4
Benedetti, J.K.5
Baker, A.F.6
Hackett, C.B.7
Urba, S.G.8
Zaner, K.S.9
Blanke, C.D.10
-
52
-
-
79951532323
-
Final results of a phase II study of modified FOLFOX6 and erlotinib in patients with metastatic adenocarcinoma of the esophagus and gastroesophageal junction
-
Abstract 4050
-
Wainberg, Z.A.; Lin, L.S.; DiCarlo, B.; Dao, K.M.; Patel, L.; Park, D.J.; Wang, H.J.; Elashoff, R.; Ryba, N.; Hecht, J.R. Final results of a phase II study of modified FOLFOX6 and erlotinib in patients with metastatic adenocarcinoma of the esophagus and gastroesophageal junction. J. Clin. Oncol. 2010, 28, Abstract 4050.
-
(2010)
J. Clin. Oncol
, vol.28
-
-
Wainberg, Z.A.1
Lin, L.S.2
Dicarlo, B.3
Dao, K.M.4
Patel, L.5
Park, D.J.6
Wang, H.J.7
Elashoff, R.8
Ryba, N.9
Hecht, J.R.10
-
53
-
-
84866759547
-
Metastatic gastric cancer-focus on targeted therapies
-
Meza-Junco, M.; Sawyer, M.B. Metastatic gastric cancer-focus on targeted therapies. Biologics 2012, 6, 137-146.
-
(2012)
Biologics
, vol.6
, pp. 137-146
-
-
Meza-Junco, M.1
Sawyer, M.B.2
-
54
-
-
84855290961
-
HER-2 evaluation in a specific gastric cancer population with the highest rate of mortality in Spain
-
Cidon, E.U.; Centeno, R.G.; Lagarto, E.G.; Peral, J.I. HER-2 evaluation in a specific gastric cancer population with the highest rate of mortality in Spain. J. Oncol. 2011, 2011, 391564.
-
(2011)
J. Oncol
, pp. 391564
-
-
Cidon, E.U.1
Centeno, R.G.2
Lagarto, E.G.3
Peral, J.I.4
-
55
-
-
79960084377
-
Anti-HER agents in gastric cancer: From bench to bedside
-
Fornaro, L.; Lucchesi, M.; Caparello, C.; Vasile, E.; Caponi, S.; Ginocchi, L.; Masi, G.; Falcone, A. Anti-HER agents in gastric cancer: From bench to bedside. Nat. Rev. Gastroenterol. Hepatol. 2011, 8, 369-383.
-
(2011)
Nat. Rev. Gastroenterol. Hepatol
, vol.8
, pp. 369-383
-
-
Fornaro, L.1
Lucchesi, M.2
Caparello, C.3
Vasile, E.4
Caponi, S.5
Ginocchi, L.6
Masi, G.7
Falcone, A.8
-
56
-
-
79952904409
-
Critical appraisal of T in treatment of advanced stomach cancer
-
Meza-Junco, J.; Au, H.J.; Sawyer, M.B. Critical appraisal of T in treatment of advanced stomach cancer. Cancer Manag. Res. 2011, 3, 57-64.
-
(2011)
Cancer Manag. Res
, vol.3
, pp. 57-64
-
-
Meza-Junco, J.1
Au, H.J.2
Sawyer, M.B.3
-
57
-
-
33748154637
-
HER-2/neu amplification is an independent prognostic factor in gastric cancer
-
Park, D.I.; Yun, J.W.; Park, J.H.; Oh, S.J.; Kim, H.J.; Cho, Y.K.; Sohn, C.I.; Jeon, W.K.; Kim, B.I.; Yoo, C.H. et al. HER-2/neu amplification is an independent prognostic factor in gastric cancer. Dig. Dis. Sci. 2006, 51, 1371-1379.
-
(2006)
Dig. Dis. Sci
, vol.51
, pp. 1371-1379
-
-
Park, D.I.1
Yun, J.W.2
Park, J.H.3
Oh, S.J.4
Kim, H.J.5
Cho, Y.K.6
Sohn, C.I.7
Jeon, W.K.8
Kim, B.I.9
Yoo, C.H.10
-
58
-
-
50849134281
-
HER2-positive advanced gastric cancer: Similar HER2-positivity levels to breast cancer
-
Abstract 3541
-
Lordick, F.; Bang, Y.J.; Kang, Y.K.; Otero Reyes, D.; Manikhas, G.M.; Shen, L. HER2-positive advanced gastric cancer: Similar HER2-positivity levels to breast cancer. Eur. J. Cancer 2007, 5, Abstract 3541
-
(2007)
Eur. J. Cancer
, vol.5
-
-
Lordick, F.1
Bang, Y.J.2
Kang, Y.K.3
Otero, R.D.4
Manikhas, G.M.5
Shen, L.6
-
59
-
-
67650395450
-
Incidence of gastric and gastroesophageal cancer in the ToGa trial: Correlation with HER2 positivity
-
Abstract 11
-
Kang, Y.; Bang, Y.; Lordick, F.; Park, S.; Sawaki, A.; Chung, H.; Shen, L.; Xu, J.M.; Leon-Chong, J.; van Cutsem, E. Incidence of gastric and gastroesophageal cancer in the ToGa trial: Correlation with HER2 positivity. Gastrointestinal Cancers Symposium (ASCO) 2008, 75, Abstract 11.
-
(2008)
Gastrointestinal Cancers Symposium (ASCO)
, vol.75
-
-
Kang, Y.1
Bang, Y.2
Lordick, F.3
Park, S.4
Sawaki, A.5
Chung, H.6
Shen, L.7
Xu, J.M.8
Leon-Chong, J.9
van Cutsem, E.10
-
60
-
-
38749149510
-
Tinhibits the growth of human gastric cancer cell lines with HER2 amplification synergistically with cis
-
Kim, S.Y.; Kim, H.P.; Kim, Y.J.; Oh do, Y.; Im, S.A.; Lee, D.; Jong, H.S.; Kim, T.Y.; Bang, Y.J. Tinhibits the growth of human gastric cancer cell lines with HER2 amplification synergistically with cis. Int. J. Oncol. 2008, 32, 89-95.
-
(2008)
Int. J. Oncol
, vol.32
, pp. 89-95
-
-
Kim, S.Y.1
Kim, H.P.2
Kim, Y.J.3
do Oh, Y.4
Im, S.A.5
Lee, D.6
Jong, H.S.7
Kim, T.Y.8
Bang, Y.J.9
-
61
-
-
33947320114
-
Antitumor activity of T in combination with chemotherapy in human gastric cancer xenograft models
-
Fujimoto-Ouchi, K.; Sekiguchi, F.; Yasuno, H.; Moriya, Y.; Mori, K.; Tanaka, Y. Antitumor activity of T in combination with chemotherapy in human gastric cancer xenograft models. Cancer Chemother. Pharmacol. 2007, 59, 795-799.
-
(2007)
Cancer Chemother. Pharmacol
, vol.59
, pp. 795-799
-
-
Fujimoto-Ouchi, K.1
Sekiguchi, F.2
Yasuno, H.3
Moriya, Y.4
Mori, K.5
Tanaka, Y.6
-
62
-
-
42449156456
-
Phase II of T and cis in patients (pts) with advanced gastric cancer (AGC) with HER2/neu overexpression/amplification
-
Abstract 4613
-
Cortés-Funes, H.; Rivera, F.; Alés, I.; Márquez, A.; Velasco, A.; Colomer, R.; García-Carbonero, R.; Sastre, J.; Guerra, J.; Grávalos, C. Phase II of T and cis in patients (pts) with advanced gastric cancer (AGC) with HER2/neu overexpression/amplification. J. Clin. Oncol. 2007, 25, Abstract 4613.
-
(2007)
J. Clin. Oncol
, vol.25
-
-
Cortés-Funes, H.1
Rivera, F.2
Alés, I.3
Márquez, A.4
Velasco, A.5
Colomer, R.6
García-Carbonero, R.7
Sastre, J.8
Guerra, J.9
Grávalos, C.10
-
63
-
-
33846227021
-
Phase I/II study of T, paclitaxel, cis and radiation for locally advanced, HER2 overexpressing, esophageal adenocarcinoma
-
Safran, H.; Dipetrillo, T.; Akerman, P.; Ng, T.; Evans, D.; Steinhoff, M.; Benton, D.; Purviance, J.; Goldstein, L.; Tantravahi, U. et al. Phase I/II study of T, paclitaxel, cis and radiation for locally advanced, HER2 overexpressing, esophageal adenocarcinoma. Int. J. Radiat. Oncol. Biol. Phys. 2007, 67, 405-409.
-
(2007)
Int. J. Radiat. Oncol. Biol. Phys
, vol.67
, pp. 405-409
-
-
Safran, H.1
Dipetrillo, T.2
Akerman, P.3
Ng, T.4
Evans, D.5
Steinhoff, M.6
Benton, D.7
Purviance, J.8
Goldstein, L.9
Tantravahi, U.10
-
64
-
-
38649093257
-
S0413: A phase II SWOG study of GW572016 (lapatinib) as first line therapy in patients (pts) with advanced or metastatic gastric cancer
-
Abstract 4621
-
Iqbal, S.; Goldman, B.; Lenz, H.J.; Fenoglio-Preiser, C.M.; Blanke, C.D. S0413: A phase II SWOG study of GW572016 (lapatinib) as first line therapy in patients (pts) with advanced or metastatic gastric cancer. J. Clin. Oncol. 2007, 25, Abstract 4621.
-
(2007)
J. Clin. Oncol
, vol.25
-
-
Iqbal, S.1
Goldman, B.2
Lenz, H.J.3
Fenoglio-Preiser, C.M.4
Blanke, C.D.5
-
65
-
-
84862250597
-
Target-specific, histology independent, randomized discontinuation study of lapatinib in patients with HER2-amplified solid tumors
-
Galsky, M.D.; von Hoff, D.D.; Neubauer, M.; Anderson, T.; Fleming, M.; Nagarwala, Y.; Mahoney, J.M.; Midwinter, D.; Vocila, L.; Zaks, T.Z. Target-specific, histology independent, randomized discontinuation study of lapatinib in patients with HER2-amplified solid tumors. Invest. New Drugs 2012, 30, 695-701.
-
(2012)
Invest. New Drugs
, vol.30
, pp. 695-701
-
-
Galsky, M.D.1
von Hoff, D.D.2
Neubauer, M.3
Anderson, T.4
Fleming, M.5
Nagarwala, Y.6
Mahoney, J.M.7
Midwinter, D.8
Vocila, L.9
Zaks, T.Z.10
-
66
-
-
77953453066
-
Lapatinib monotherapy in recurrent upper gastrointestinal malignancy: Phase II efficacy and biomarker analyses
-
Abstract 43
-
Hecht, J.R.; Urba, S.G.; Koehler, M.; Ellis, C.; Gagnon, R.; Kemner, A.; Versola, N.; Spector, M.; Press, M.F.; Richel, D.J. Lapatinib monotherapy in recurrent upper gastrointestinal malignancy: Phase II efficacy and biomarker analyses. Gastrointestinal Cancers Symposium (ASCO) 2008, Abstract 43.
-
(2008)
Gastrointestinal Cancers Symposium (ASCO)
-
-
Hecht, J.R.1
Urba, S.G.2
Koehler, M.3
Ellis, C.4
Gagnon, R.5
Kemner, A.6
Versola, N.7
Spector, M.8
Press, M.F.9
Richel, D.J.10
-
67
-
-
79952977646
-
Lapatinib 1 capecitabine in advanced gastric cancer: An open-label phase II study of non ERBB2-targeted disease
-
Lenz, H.J.; Zhang, W.; Kemner, A.M.; Kaneko, T.; Yang, D.; Franklin, N.; Moon, H. Lapatinib 1 capecitabine in advanced gastric cancer: An open-label phase II study of non ERBB2-targeted disease. European Society of Medical Oncology Congress (ESMO) 2010, 21, S817.
-
(2010)
European Society of Medical Oncology Congress (ESMO)
, vol.21
-
-
Lenz, H.J.1
Zhang, W.2
Kemner, A.M.3
Kaneko, T.4
Yang, D.5
Franklin, N.6
Moon, H.7
-
68
-
-
79960080459
-
Lapatinib in combination with ECF/X in EGFR1 or HER2-overexpressing first-line metastatic gastric cancer (GC): A phase II randomized placebo controlled trial (EORTC 40071)
-
Abstract 205
-
Roth, A.; Moehler, M.H.; Mauer, M.; Schad, A.; Karrasch, M.; Praet, M.; Lim, M.L.; Das-Gupta, A.; Lutz, M.P. Lapatinib in combination with ECF/X in EGFR1 or HER2-overexpressing first-line metastatic gastric cancer (GC): A phase II randomized placebo controlled trial (EORTC 40071). J. Clin. Oncol. 2010, 28, Abstract 205.
-
(2010)
J. Clin. Oncol
, vol.28
-
-
Roth, A.1
Moehler, M.H.2
Mauer, M.3
Schad, A.4
Karrasch, M.5
Praet, M.6
Lim, M.L.7
Das-Gupta, A.8
Lutz, M.P.9
-
69
-
-
79960081156
-
Interim safety analysis from TYTAN: A phase III Asian study of lapatinib in combination with paclitaxel as second-line therapy in gastric cancer
-
Abstract 4057
-
Satoh, T.; Bang, Y.; Wang, J.; Xu, J.; Chung, H.C.; Yeh, K.; Chen, J.; Mukaiyama, A.; Yoshida, P.; Ohtsu, A. Interim safety analysis from TYTAN: A phase III Asian study of lapatinib in combination with paclitaxel as second-line therapy in gastric cancer. J. Clin. Oncol. 2010, 28, Abstract 4057.
-
(2010)
J. Clin. Oncol
, vol.28
-
-
Satoh, T.1
Bang, Y.2
Wang, J.3
Xu, J.4
Chung, H.C.5
Yeh, K.6
Chen, J.7
Mukaiyama, A.8
Yoshida, P.9
Ohtsu, A.10
-
71
-
-
0031039243
-
The biology of vascular endothelial growth factor
-
Ferrara, N.; Davis-Smyth, T. The biology of vascular endothelial growth factor. Endocr. Rev. 1997, 18, 4-25.
-
(1997)
Endocr. Rev
, vol.18
, pp. 4-25
-
-
Ferrara, N.1
Davis-Smyth, T.2
-
72
-
-
0034729146
-
Plasma concentration of VEGF and bFGF in patients with gastric carcinoma
-
Yoshikawa, T.; Tsuburaya, A.; Kobayashi, O.; Sairenji, M.; Motohashi, H.; Yanoma, S.; Noguchi, Y. Plasma concentration of VEGF and bFGF in patients with gastric carcinoma. Cancer Lett. 2000, 153, 7-12.
-
(2000)
Cancer Lett
, vol.153
, pp. 7-12
-
-
Yoshikawa, T.1
Tsuburaya, A.2
Kobayashi, O.3
Sairenji, M.4
Motohashi, H.5
Yanoma, S.6
Noguchi, Y.7
-
73
-
-
0030066037
-
Prognostic value of vascular endothelial growth factor expression in gastric carcinoma
-
Maeda, K.; Chung, Y.S.; Ogawa, Y.; Takatsuka, S.; Kang, S.M.; Ogawa, M.; Sawada, T.; Sowa, M. Prognostic value of vascular endothelial growth factor expression in gastric carcinoma. Cancer 1996, 7, 858-863.
-
(1996)
Cancer
, vol.7
, pp. 858-863
-
-
Maeda, K.1
Chung, Y.S.2
Ogawa, Y.3
Takatsuka, S.4
Kang, S.M.5
Ogawa, M.6
Sawada, T.7
Sowa, M.8
-
74
-
-
0036292971
-
Circulating VEGF levels in the serum of gastric cancer patients: Correlation with pathological variables, patient survival, and tumor surgery
-
Karayiannakis, A.J.; Syrigos, K.N.; Polychronidis, A.; Zbar, A.; Kouraklis, G.; Simopoulos, C.; Karatzas, G. Circulating VEGF levels in the serum of gastric cancer patients: Correlation with pathological variables, patient survival, and tumor surgery. Ann. Surg. 2002, 236, 37-42.
-
(2002)
Ann. Surg
, vol.236
, pp. 37-42
-
-
Karayiannakis, A.J.1
Syrigos, K.N.2
Polychronidis, A.3
Zbar, A.4
Kouraklis, G.5
Simopoulos, C.6
Karatzas, G.7
-
75
-
-
2542561964
-
Bevacizumab plus iri, fluorouracil, and leucovorin for metastatic colorectal cancer
-
Hurwitz, H.; Fehrenbacher, L.; Novotny, W.; Cartwright, T.; Hainsworth, J.; Heim, W.; Berlin, J.; Baron, A.; Griffing, S.; Holmgren, E. et al. Bevacizumab plus iri, fluorouracil, and leucovorin for metastatic colorectal cancer. N. Engl. J. Med. 2004, 350, 2335-2342.
-
(2004)
N. Engl. J. Med
, vol.350
, pp. 2335-2342
-
-
Hurwitz, H.1
Fehrenbacher, L.2
Novotny, W.3
Cartwright, T.4
Hainsworth, J.5
Heim, W.6
Berlin, J.7
Baron, A.8
Griffing, S.9
Holmgren, E.10
-
76
-
-
33845490014
-
Paclitaxel-carboplatin alone or with bevacizumab for non-small-cell lung cancer
-
Sandler, A.; Gray, R.; Perry, M.C.; Brahmer, J.; Schiller, J.H.; Dowlati, A.; Lilenbaum, R.; Johnson, D.H.; Sandler, A.; Gray, R. et al. Paclitaxel-carboplatin alone or with bevacizumab for non-small-cell lung cancer. N. Engl. J. Med. 2006, 355, 2542-2550.
-
(2006)
N. Engl. J. Med
, vol.355
, pp. 2542-2550
-
-
Sandler, A.1
Gray, R.2
Perry, M.C.3
Brahmer, J.4
Schiller, J.H.5
Dowlati, A.6
Lilenbaum, R.7
Johnson, D.H.8
Sandler, A.9
Gray, R.10
-
77
-
-
37549040613
-
Paclitaxel plus bevacizumab versus paclitaxel alone for metastatic breast cancer
-
Miller, K.; Wang, M.; Gralow, J.; Dickler, M.; Cobleigh, M.; Perez, E.A.; Shenkier, T.; Cella, D.; Davidson, N.E. Paclitaxel plus bevacizumab versus paclitaxel alone for metastatic breast cancer. N. Engl. J. Med. 2007, 357, 2666-2676.
-
(2007)
N. Engl. J. Med
, vol.357
, pp. 2666-2676
-
-
Miller, K.1
Wang, M.2
Gralow, J.3
Dickler, M.4
Cobleigh, M.5
Perez, E.A.6
Shenkier, T.7
Cella, D.8
Davidson, N.E.9
-
78
-
-
33846629672
-
Multicenter phase II study of iri, cis, and bevacizumab in patients with metastatic gastric or gastroesophageal junction adenocarcinoma
-
Shah, M.A.; Ramanathan, R.K.; Ilson, D.H.; Levnor, A.; D'Adamo, D.; O'Reilly, E.; Tse, A.; Trocola, R.; Schwartz, L.; Capanu, M. et al. Multicenter phase II study of iri, cis, and bevacizumab in patients with metastatic gastric or gastroesophageal junction adenocarcinoma. J. Clin. Oncol. 2006, 24, 5201-5206.
-
(2006)
J. Clin. Oncol
, vol.24
, pp. 5201-5206
-
-
Shah, M.A.1
Ramanathan, R.K.2
Ilson, D.H.3
Levnor, A.4
D'Adamo, D.5
O'Reilly, E.6
Tse, A.7
Trocola, R.8
Schwartz, L.9
Capanu, M.10
-
79
-
-
67650450330
-
FOLFOX6 and bevacizumab (FOLFOX6/B) for metastatic esophageal, gastroesophageal (GE) and gastric cancer (G) adenocarcinoma: A single institution's initial clinical experience
-
Abstract 74
-
Cohenuram, M.K.; Lacy, J. FOLFOX6 and bevacizumab (FOLFOX6/B) for metastatic esophageal, gastroesophageal (GE) and gastric cancer (G) adenocarcinoma: A single institution's initial clinical experience. Gastrointestinal Cancers Symposium (ASCO) 2008, Abstract 74.
-
(2008)
Gastrointestinal Cancers Symposium (ASCO)
-
-
Cohenuram, M.K.1
Lacy, J.2
-
80
-
-
77957160694
-
A phase II study of bevacizumab, oxaliplatin, and docetaxel in locally advanced and metastatic gastric and gastroesophageal junction cancers
-
El-Rayes, B.F.; Zalupski, M.; Bekai-Saab, T.; Heilbrun, L.K.; Hammad, N.; Patel, B.; Urba, S.; Shields, A.F.; Vaishampayan, U.; Dawson, S. et al. A phase II study of bevacizumab, oxaliplatin, and docetaxel in locally advanced and metastatic gastric and gastroesophageal junction cancers. Ann. Oncol. 2010, 21, 1999-2004.
-
(2010)
Ann. Oncol
, vol.21
, pp. 1999-2004
-
-
El-Rayes, B.F.1
Zalupski, M.2
Bekai-Saab, T.3
Heilbrun, L.K.4
Hammad, N.5
Patel, B.6
Urba, S.7
Shields, A.F.8
Vaishampayan, U.9
Dawson, S.10
-
81
-
-
56849089479
-
Phase II trial of docetaxel, cis, iri, and bevacizumab in metastatic esophagogastric cancer
-
Abstract 4552
-
Enzinger, P.C.; Ryan, D.P.; Regan, E.M.; Lehman, N.; Abrams, T.A.; Hezel, A.F.; Fidias, P.; Sequist, L.V.; Blaszkowsky, L.S.; Fuchs, C.S. Phase II trial of docetaxel, cis, iri, and bevacizumab in metastatic esophagogastric cancer. J. Clin. Oncol. 2008, 26, Abstract 4552.
-
(2008)
J. Clin. Oncol
, vol.26
-
-
Enzinger, P.C.1
Ryan, D.P.2
Regan, E.M.3
Lehman, N.4
Abrams, T.A.5
Hezel, A.F.6
Fidias, P.7
Sequist, L.V.8
Blaszkowsky, L.S.9
Fuchs, C.S.10
-
82
-
-
80053573446
-
Bevacizumab in combination with chemotherapy as first-line therapy in advanced gastric cancer: A randomized, double-blind, placebo-controlled phase III study
-
Ohtsu, A.; Shah, M.A.; van Cutsem, E.; Rha, S.Y.; Sawaki, A.; Park, S.R.; Lim, H.Y.; Yamada, Y.; Wu, J.; Langer, B. et al. Bevacizumab in combination with chemotherapy as first-line therapy in advanced gastric cancer: A randomized, double-blind, placebo-controlled phase III study. J. Clin. Oncol. 2011, 29, 3968-3976.
-
(2011)
J. Clin. Oncol
, vol.29
, pp. 3968-3976
-
-
Ohtsu, A.1
Shah, M.A.2
van Cutsem, E.3
Rha, S.Y.4
Sawaki, A.5
Park, S.R.6
Lim, H.Y.7
Yamada, Y.8
Wu, J.9
Langer, B.10
-
83
-
-
79952355358
-
Phase II study of modified docetaxel, cis, and fluorouracil with bevacizumab in patients with metastatic gastroesophageal adenocarcinoma
-
Shah, M.A.; Jhawer, M.; Ilson, D.H.; Lefkowitz, R.A.; Robinson, E.; Capanu, M.; Kelsen, D.P. Phase II study of modified docetaxel, cis, and fluorouracil with bevacizumab in patients with metastatic gastroesophageal adenocarcinoma. J. Clin. Oncol. 2011, 29, 868-874.
-
(2011)
J. Clin. Oncol
, vol.29
, pp. 868-874
-
-
Shah, M.A.1
Jhawer, M.2
Ilson, D.H.3
Lefkowitz, R.A.4
Robinson, E.5
Capanu, M.6
Kelsen, D.P.7
-
84
-
-
84875238747
-
Survival analysis according to disease subtype in AVAGAST: First-line capecitabine and cis plus bevacizumab or placebo in patients with advanced gastric cancer
-
Abstract 5
-
Shah, M.A.; van Cutsem, E.; Kang, Y.K.; Dakhil, S.R.; Satoh, T.; Chin, K.; Bang, Y.J.; Bu, L.; Bilic, G.; Ohtsu, A. Survival analysis according to disease subtype in AVAGAST: First-line capecitabine and cis plus bevacizumab or placebo in patients with advanced gastric cancer. Gastrointestinal Cancers Symposium (ASCO) 2012, 30, Abstract 5.
-
(2012)
Gastrointestinal Cancers Symposium (ASCO)
, vol.30
-
-
Shah, M.A.1
van Cutsem, E.2
Kang, Y.K.3
Dakhil, S.R.4
Satoh, T.5
Chin, K.6
Bang, Y.J.7
Bu, L.8
Bilic, G.9
Ohtsu, A.10
-
85
-
-
77958495206
-
AVAGAST: A randomized, double-blind, placebo-controlled, phase III study of first-line capecitabine and cis plus bevacizumab or placebo in patients with advanced gastric cancer (AGC)
-
Abstract LBA4007
-
Kang, Y.; Ohtsu, A.; van Cutsem, E.; Rha, S.Y.; Sawaki, A.; Park, S.; Lim, H.; Wu, J.; Langer, B.; Shah, M.A. AVAGAST: A randomized, double-blind, placebo-controlled, phase III study of first-line capecitabine and cis plus bevacizumab or placebo in patients with advanced gastric cancer (AGC). J. Clin. Oncol. 2010, 28, Abstract LBA4007.
-
(2010)
J. Clin. Oncol
, pp. 28
-
-
Kang, Y.1
Ohtsu, A.2
van Cutsem, E.3
Rha, S.Y.4
Sawaki, A.5
Park, S.6
Lim, H.7
Wu, J.8
Langer, B.9
Shah, M.A.10
-
86
-
-
84875277634
-
Survival analysis by pooling risk factors in AVAGAST: First-line capecitabine plus bevacizumab or placebo in patients with advanced gastric cancer
-
Abstract 4119
-
Kang, Y.; Ohtsu, A.; van Cutsem, E.; Roman, L.; Nunes, J.; Li, C.; Otero, D.; Rivera, F.; Aprile, G.; Pimentel Alvarez P.R.; et al. Survival analysis by pooling risk factors in AVAGAST: First-line capecitabine plus bevacizumab or placebo in patients with advanced gastric cancer. J. Clin. Oncol. 2011, 29, Abstract 4119.
-
(2011)
J. Clin. Oncol
, vol.29
-
-
Kang, Y.1
Ohtsu, A.2
van Cutsem, E.3
Roman, L.4
Nunes, J.5
Li, C.6
Otero, D.7
Rivera, F.8
Aprile, G.9
Pimentel, A.P.R.10
-
87
-
-
80052758607
-
Tumor and blood plasma biomarker analyses in the AVAGAST phase III randomized study of first-line bevacizumab + capecitabine/cis in patients with advanced gastric cancer
-
Shah, M.; Kang, Y.K.; Ohtsu, A.; Delmar, P.; Foernzler, D.; Langer, B.; Scherer, S.; van Cutsem, E. Tumor and blood plasma biomarker analyses in the AVAGAST phase III randomized study of first-line bevacizumab + capecitabine/cis in patients with advanced gastric cancer. European Society of Medical Oncology Congress (ESMO) 2010, 21, S176.
-
(2010)
European Society of Medical Oncology Congress (ESMO)
, vol.21
-
-
Shah, M.1
Kang, Y.K.2
Ohtsu, A.3
Delmar, P.4
Foernzler, D.5
Langer, B.6
Scherer, S.7
van Cutsem, E.8
-
88
-
-
84875262761
-
ST03: A randomized trial of perioperative epirubicin, cis plus capecitabine (ECX) with or without bevacizumab (B) in patients (pts) with operable gastric, oesophagogastric junction (OGJ) or lower oesophageal adenocarcinoma
-
Abstract TPS4143
-
Smyth, E.C.; Langley, R.E.; Stenning, S.P.; Stevenson, L.; Allum, W.H.; Grabsch, H.; Alderson, D.; Riddell, A.M.; Crosby, T., Mason, R et al. ST03: A randomized trial of perioperative epirubicin, cis plus capecitabine (ECX) with or without bevacizumab (B) in patients (pts) with operable gastric, oesophagogastric junction (OGJ) or lower oesophageal adenocarcinoma. J. Clin. Oncol. 2012, 30, Abstract TPS4143.
-
(2012)
J. Clin. Oncol
, vol.30
-
-
Smyth, E.C.1
Langley, R.E.2
Stenning, S.P.3
Stevenson, L.4
Allum, W.H.5
Grabsch, H.6
Alderson, D.7
Riddell, A.M.8
Crosby, T.9
Mason, R.10
-
89
-
-
77649213706
-
Phase I pharmacologic and biologic study of ramucirumab (IMC-1121B), a fully human immunoglobulin G1 monoclonal antibody targeting the vascular endothelial growth factor receptor-2
-
Spratlin, J.L.; Cohen, R.B.; Eadens, M.; Gore, L.; Camidge, D.R.; Diab, S.; Leong, S.; O'Bryant, C.; Chow, L.Q.; Serkova, N.J. et al. Phase I pharmacologic and biologic study of ramucirumab (IMC-1121B), a fully human immunoglobulin G1 monoclonal antibody targeting the vascular endothelial growth factor receptor-2. J. Clin. Oncol. 2010, 28, 780-787.
-
(2010)
J. Clin. Oncol
, vol.28
, pp. 780-787
-
-
Spratlin, J.L.1
Cohen, R.B.2
Eadens, M.3
Gore, L.4
Camidge, D.R.5
Diab, S.6
Leong, S.7
O'Bryant, C.8
Chow, L.Q.9
Serkova, N.J.10
-
91
-
-
84875250922
-
A randomized, multicenter, double-blind, placebo (PBO)-controlled phase III study of paclitaxel (PTX) with or without ramucirumab (IMC-1121B; RAM) in patients (pts) with metastatic gastric adenocarcinoma, refractory to or progressive after first-line therapy with platinum (PLT) and fluoropyrimidine (FP)
-
Abstract TPS4139
-
Wilke, H.; Cunningham, D.; Ohtsu, A.; Nuber, U.; Bruns, R.; Schmitt-Bormann, B. A randomized, multicenter, double-blind, placebo (PBO)-controlled phase III study of paclitaxel (PTX) with or without ramucirumab (IMC-1121B; RAM) in patients (pts) with metastatic gastric adenocarcinoma, refractory to or progressive after first-line therapy with platinum (PLT) and fluoropyrimidine (FP). J. Clin. Oncol. 2012, 30, Abstract TPS4139
-
(2012)
J. Clin. Oncol
, vol.30
-
-
Wilke, H.1
Cunningham, D.2
Ohtsu, A.3
Nuber, U.4
Bruns, R.5
Schmitt-Bormann, B.6
-
93
-
-
84856524126
-
Phase I dose-finding study of sorafenib in combination with capecitabine and cis as a first-line treatment in patients with advanced gastric cancer
-
Kim, C.; Lee, J.L.; Choi, Y.H.; Kang, B.W.; Ryu, M.H.; Chang, H.M.; Kim, T.W.; Kang, Y.K. Phase I dose-finding study of sorafenib in combination with capecitabine and cis as a first-line treatment in patients with advanced gastric cancer. Invest. New Drugs. 2012, 30, 306-315.
-
(2012)
Invest. New Drugs
, vol.30
, pp. 306-315
-
-
Kim, C.1
Lee, J.L.2
Choi, Y.H.3
Kang, B.W.4
Ryu, M.H.5
Chang, H.M.6
Kim, T.W.7
Kang, Y.K.8
-
94
-
-
77954574658
-
Phase II study of sorafenib in combination with docetaxel and cis in the treatment of metastatic or advanced gastric and gastroesophageal junction adenocarcinoma: ECOG 5203
-
Sun, W.; Powell, M.; O'Dwyer, P.J.; Catalano, P.; Ansari, R.H.; Benson, A.B., III. Phase II study of sorafenib in combination with docetaxel and cis in the treatment of metastatic or advanced gastric and gastroesophageal junction adenocarcinoma: ECOG 5203. J. Clin. Oncol. 2010, 28, 2947-2951.
-
(2010)
J. Clin. Oncol
, vol.28
, pp. 2947-2951
-
-
Sun, W.1
Powell, M.2
O'Dwyer, P.J.3
Catalano, P.4
Ansari, R.H.5
Benson III, A.B.6
-
95
-
-
84875250595
-
Phase II study of oxaliplatin and sorafenib in advanced gastric cancer after failure of cis-fluoropyrimidine-based (PF) treatment
-
Abstract 4079
-
Gallego, R.; Martin-Richard, M.; Pericay, C.; Garcia-Foncillas, J.; Queralt, B.; Casado, E.; Feliu, J.; Vega, I.; Juez, I.; Visa L.; et al. Phase II study of oxaliplatin and sorafenib in advanced gastric cancer after failure of cis-fluoropyrimidine-based (PF) treatment. J. Clin. Oncol. 2012, 30, Abstract 4079.
-
(2012)
J. Clin. Oncol
, vol.30
-
-
Gallego, R.1
Martin-Richard, M.2
Pericay, C.3
Garcia-Foncillas, J.4
Queralt, B.5
Casado, E.6
Feliu, J.7
Vega, I.8
Juez, I.9
Visa, L.10
-
96
-
-
79958803154
-
An open-label, multicentre biomarker-oriented AIO phase II trial of sunitinib for patients with chemo-refractory advanced gastric cancer
-
Moehler, M.; Mueller, A.; Hartmann, J.T.; Ebert, M.P.; Al-Batran, S.E.; Reimer, P.; Weihrauch, M.; Lordick, F.; Trarbach, T.; Biesterfeld, S. et al. An open-label, multicentre biomarker-oriented AIO phase II trial of sunitinib for patients with chemo-refractory advanced gastric cancer. Eur. J. Cancer 2011, 47, 1511-1520.
-
(2011)
Eur. J. Cancer
, vol.47
, pp. 1511-1520
-
-
Moehler, M.1
Mueller, A.2
Hartmann, J.T.3
Ebert, M.P.4
Al-Batran, S.E.5
Reimer, P.6
Weihrauch, M.7
Lordick, F.8
Trarbach, T.9
Biesterfeld, S.10
-
97
-
-
82955241985
-
Phase II study of sunitinib as second-line treatment for advanced gastric cancer
-
Bang, Y.J.; Kang, Y.K.; Kang, W.K.; Boku, N.; Chung, H.C.; Chen, J.S.; Doi, T.; Sun, Y.; Shen, L.; Qin, S et al. Phase II study of sunitinib as second-line treatment for advanced gastric cancer. Invest. New Drugs 2011, 29, 1449-1458.
-
(2011)
Invest. New Drugs
, vol.29
, pp. 1449-1458
-
-
Bang, Y.J.1
Kang, Y.K.2
Kang, W.K.3
Boku, N.4
Chung, H.C.5
Chen, J.S.6
Doi, T.7
Sun, Y.8
Shen, L.9
Qin, S.10
-
98
-
-
84862256003
-
Novel targeted agents for gastric cancer
-
Liu, L.; Wu, N.; Li, J. Novel targeted agents for gastric cancer. J. Hematol. Oncol. 2012, 5, 31.
-
(2012)
J. Hematol. Oncol
, vol.5
, pp. 31
-
-
Liu, L.1
Wu, N.2
Li, J.3
-
99
-
-
67651242368
-
Current status of cediranib: The rapid development of a novel anti-angiogenic therapy
-
Lindsay, C.R.; MacPherson, I.R.; Cassidy, J. Current status of cediranib: The rapid development of a novel anti-angiogenic therapy. Future Oncol. 2009, 5, 421-432.
-
(2009)
Future Oncol
, vol.5
, pp. 421-432
-
-
Lindsay, C.R.1
Macpherson, I.R.2
Cassidy, J.3
-
100
-
-
84856736532
-
Phase I study of cediranib in combination with cis plus fluoropyrimidine (S-1 or capecitabine) in Japanese patients with previously untreated advanced gastric cancer
-
Satoh, T.; Yamada, Y.; Muro, K.; Hayashi, H.; Shimada, Y.; Takahari, D.; Taku, K.; Nakajima, T.E.; Shi, X.; Brown, K.H. et al. Phase I study of cediranib in combination with cis plus fluoropyrimidine (S-1 or capecitabine) in Japanese patients with previously untreated advanced gastric cancer. Cancer Chemother. Pharmacol. 2011, 69, 439-446.
-
(2011)
Cancer Chemother. Pharmacol
, vol.69
, pp. 439-446
-
-
Satoh, T.1
Yamada, Y.2
Muro, K.3
Hayashi, H.4
Shimada, Y.5
Takahari, D.6
Taku, K.7
Nakajima, T.E.8
Shi, X.9
Brown, K.H.10
-
101
-
-
79959208066
-
YN968D1 is a novel and selective inhibitor of vascular endothelial growth factor receptor-2 tyrosine kinase with potent activity in vitro and in vivo
-
Tian, S.; Quan, H.; Xie, C.; Guo, H.; Lü, F.; Xu, Y.; Li, J.; Lou, L. YN968D1 is a novel and selective inhibitor of vascular endothelial growth factor receptor-2 tyrosine kinase with potent activity in vitro and in vivo. Cancer Sci. 2011, 102, 1374-1380.
-
(2011)
Cancer Sci
, vol.102
, pp. 1374-1380
-
-
Tian, S.1
Quan, H.2
Xie, C.3
Guo, H.4
Lü, F.5
Xu, Y.6
Li, J.7
Lou, L.8
-
103
-
-
84875238859
-
A phase 2 study of telatinib (TEL) in combination with capecitabine (X) and cis (P) as first-line treatment in patients (pts) with advanced gastric or gastro-esophageal junction (GEJ) cancer
-
TEL0805 trial:, Available online, (accessed on 20 November 2012)
-
TEL0805 trial: A phase 2 study of telatinib (TEL) in combination with capecitabine (X) and cis (P) as first-line treatment in patients (pts) with advanced gastric or gastro-esophageal junction (GEJ) cancer. A Study of Telatinib in Combination with Chemotherapy in Subjects With Advanced Gastric Cancer. Available online: http://clinicaltrials.gov/show/NCT00952497/ (accessed on 20 November 2012).
-
A Study of Telatinib In Combination With Chemotherapy In Subjects With Advanced Gastric Cancer
-
-
-
104
-
-
77951635629
-
Multicenter phase II study of everolimus in patients with previously treated metastatic gastric cancer
-
Doi, T.; Muro, K.; Boku, N.; Yamada, Y.; Nishina, T.; Takiuchi, H.; Komatsu, Y.; Hamamoto, Y.; Ohno, N.; Fujita, Y. et al. Multicenter phase II study of everolimus in patients with previously treated metastatic gastric cancer. J. Clin. Oncol. 2010, 28, 1904-1910.
-
(2010)
J. Clin. Oncol
, vol.28
, pp. 1904-1910
-
-
Doi, T.1
Muro, K.2
Boku, N.3
Yamada, Y.4
Nishina, T.5
Takiuchi, H.6
Komatsu, Y.7
Hamamoto, Y.8
Ohno, N.9
Fujita, Y.10
-
105
-
-
84875271165
-
Everolimus in patients with previously treated metastatic gastric cancer: Final results of a multicenter phase II study
-
Abstract 52
-
Takiuchi, H.; Doi, T.; Muro, K.; Yamada, Y.; Boku, N.; Nishina, T.; Komatsu, Y.; Hamamoto, Y.; Ohno, N.; Ohtsu, A. Everolimus in patients with previously treated metastatic gastric cancer: Final results of a multicenter phase II study. Gastrointestinal Cancers Symposium (ASCO) 2010, Abstract 52
-
(2010)
Gastrointestinal Cancers Symposium (ASCO)
-
-
Takiuchi, H.1
Doi, T.2
Muro, K.3
Yamada, Y.4
Boku, N.5
Nishina, T.6
Komatsu, Y.7
Hamamoto, Y.8
Ohno, N.9
Ohtsu, A.10
-
106
-
-
84861392332
-
Phase III trial of everolimus (EVE) in previously treated patients with advanced gastric cancer (AGC): GRANITE-1
-
LBA3
-
Van Cutsem, E.; Yeh, K.H.; Bang, Y.J.; Shen, L.; Ajani, J.A.; Bai, Y.; Chung, H.C.; Pan, H.M.; Chin, K.; Muro, K. et al. Phase III trial of everolimus (EVE) in previously treated patients with advanced gastric cancer (AGC): GRANITE-1. J. Clin. Oncol. 2012, 4, LBA3.
-
(2012)
J. Clin. Oncol
, vol.4
-
-
van Cutsem, E.1
Yeh, K.H.2
Bang, Y.J.3
Shen, L.4
Ajani, J.A.5
Bai, Y.6
Chung, H.C.7
Pan, H.M.8
Chin, K.9
Muro, K.10
-
107
-
-
33646811208
-
Expression of Polo-Like Kinase 1 (PLK1) Protein Predicts the Survival of Patients with Gastric Carcinoma
-
Kanaji, S.; Saito, H.; Tsujitani, S.; Matsumoto, S.; Tatebe, S.; Kondo, A.; Ozaki, M.; Ito, H.; Ikeguchi, M. Expression of Polo-Like Kinase 1 (PLK1) Protein Predicts the Survival of Patients with Gastric Carcinoma. Oncology 2006, 70, 126-133.
-
(2006)
Oncology
, vol.70
, pp. 126-133
-
-
Kanaji, S.1
Saito, H.2
Tsujitani, S.3
Matsumoto, S.4
Tatebe, S.5
Kondo, A.6
Ozaki, M.7
Ito, H.8
Ikeguchi, M.9
-
108
-
-
33750379151
-
A phase I repeated dose escalation study of the Polo-like kinase 1 inhibitor BI 2536 in patients with advanced solid tumours
-
Abstract 2038
-
Hofheinz, R.; Hochhaus, A.; Al-Batran, S.; Nanci, A.; Reichardt, V.; Trommeshauser, D.; Hoffmann, M.; Steegmaier, M.; Munzert, G.; Jäger, E. A phase I repeated dose escalation study of the Polo-like kinase 1 inhibitor BI 2536 in patients with advanced solid tumours. J. Clin. Oncol. 2006, 20, Abstract 2038.
-
(2006)
J. Clin. Oncol
, vol.20
-
-
Hofheinz, R.1
Hochhaus, A.2
Al-Batran, S.3
Nanci, A.4
Reichardt, V.5
Trommeshauser, D.6
Hoffmann, M.7
Steegmaier, M.8
Munzert, G.9
Jäger, E.10
-
109
-
-
84997909291
-
c-MET as a potential therapeutic target and biomarker in cancer
-
Sierra, J.R.; Tsao, M.S. c-MET as a potential therapeutic target and biomarker in cancer. Ther. Adv. Med. Oncol. 2011, 3, S21-S35.
-
(2011)
Ther. Adv. Med. Oncol
, vol.3
-
-
Sierra, J.R.1
Tsao, M.S.2
-
110
-
-
79551693816
-
C-met as a therapeutic target for metastatic potential of gastric cancer
-
Cho, H.; Zhang, X.; Jung, M.; Kwon, W.; Jung, J.; Jeung, H.; Roh, J.H.; Chung, H.C.; Rha; S.H. C-met as a therapeutic target for metastatic potential of gastric cancer. J. Clin. Oncol. 2010, 28, e14568.
-
(2010)
J. Clin. Oncol
, vol.28
-
-
Cho, H.1
Zhang, X.2
Jung, M.3
Kwon, W.4
Jung, J.5
Jeung, H.6
Roh, J.H.7
Chung, H.C.8
Rha, S.H.9
-
111
-
-
77950558200
-
Assessment of two dosing schedules of GSK1363089 (GSK089), a dual MET/VEGFR2 inhibitor, in metastatic gastric cancer (GC): Interim results of a multicenter phase II study
-
Jhawer, M.; Kindler, H.L.; Wainberg, Z.; Ford, J.; Kunz, P.; Tang, L.; McCallum, S.; Kallender, H.; Shah, M.A. Assessment of two dosing schedules of GSK1363089 (GSK089), a dual MET/VEGFR2 inhibitor, in metastatic gastric cancer (GC): Interim results of a multicenter phase II study. J. Clin. Oncol. 2009, 27, e14502.
-
(2009)
J. Clin. Oncol
, vol.27
-
-
Jhawer, M.1
Kindler, H.L.2
Wainberg, Z.3
Ford, J.4
Kunz, P.5
Tang, L.6
McCallum, S.7
Kallender, H.8
Shah, M.A.9
-
112
-
-
84875249205
-
A phase II study of tivantinib monotherapy in patients with previously treated advanced or recurrent gastric cancer
-
Abstract 4082
-
Muro, K.; Ryu, M.H.; Yasui, H.; Nishina, T.; Ryoo, B.Y.; Boku, N.; Kang, Y.K. A phase II study of tivantinib monotherapy in patients with previously treated advanced or recurrent gastric cancer. J. Clin. Oncol. 2012, 30, Abstract 4082.
-
(2012)
J. Clin. Oncol
, vol.30
-
-
Muro, K.1
Ryu, M.H.2
Yasui, H.3
Nishina, T.4
Ryoo, B.Y.5
Boku, N.6
Kang, Y.K.7
-
113
-
-
84875266104
-
Safety and Efficacy of Epirubicin, Cis, and Capecitabine (ECX) Plus Rilotumumab (R) as First-line Treatment for Unresectable Locally Advanced (LA) or Metastatic (M) Gastric or Esophagogastric Junction (EGJ) Adenocarcinoma
-
Abstract 6504
-
Iveson, T.; Donehower, R.C.; Davidenko, I.; Tjulandin, S.; Deptala, A.; Harrison, M.; Loh, E.; Jiang, Y.; Oliner, K.; Dubey, S. Safety and Efficacy of Epirubicin, Cis, and Capecitabine (ECX) Plus Rilotumumab (R) as First-line Treatment for Unresectable Locally Advanced (LA) or Metastatic (M) Gastric or Esophagogastric Junction (EGJ) Adenocarcinoma. European Society of Medical Oncology Congress (ESMO) 2011, Abstract 6504.
-
(2011)
European Society of Medical Oncology Congress (ESMO)
-
-
Iveson, T.1
Donehower, R.C.2
Davidenko, I.3
Tjulandin, S.4
Deptala, A.5
Harrison, M.6
Loh, E.7
Jiang, Y.8
Oliner, K.9
Dubey, S.10
-
115
-
-
80054071524
-
Molecularly targeted therapies in unresectable-metastatic gastric cancer. A systematic review
-
Zagouri, F.; Papadimitriou, C.A.; Dimopoulos, M.A.; Pectasides, D. Molecularly targeted therapies in unresectable-metastatic gastric cancer. A systematic review. Cancer Treat. Rev. 2011, 37, 599-610.
-
(2011)
Cancer Treat. Rev
, vol.37
, pp. 599-610
-
-
Zagouri, F.1
Papadimitriou, C.A.2
Dimopoulos, M.A.3
Pectasides, D.4
-
116
-
-
73449107243
-
Advanced Gastric Cancer: An Update and Future Directions
-
Benson, A.B. Advanced Gastric Cancer: An Update and Future Directions. Gastrointest. Cancer Res. 2008, 4, S47-S53
-
(2008)
Gastrointest. Cancer Res
, vol.4
-
-
Benson, A.B.1
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