Synthesis and evaluation of nicotinamide derivative as anti-angiogenic agents

Bioorganic and Medicinal Chemistry Letters

Volumn 23, Issue 7, 2013, Pages 2083-2088

  Choi, Hye Eun ^a   Choi, Jung Hye ^a   Lee, Jae Yeol ^a   Kim, Je Hak ^b   Kim, Ji Han ^b   Lee, Joon Kwang ^b   Kim, Gyu Il ^b   Park, Yong ^b   Chi, Yong Ha ^b   Paik, Soo Heui ^b   Lee, Joo Han ^b   Lee, Kyung Tae ^a  

^a Kyung Hee University   (South Korea)

^b Boryung Pharm Co Ltd   (South Korea)

Author keywords

Anti angiogenesis; HUVECs; Nicotinamide; Receptor tyrosine kinase; VEGFR

Indexed keywords

ANGIOGENESIS INHIBITOR; BRN 137; BRN 201; BRN 242; BRN 244; BRN 250; BRN 267; BRN 442; NICOTINAMIDE; NICOTINAMIDE DERIVATIVE; PROTEIN TYROSINE KINASE; UNCLASSIFIED DRUG; VASCULOTROPIN; VASCULOTROPIN RECEPTOR 2;

ANGIOGENESIS; ARTICLE; CELL MIGRATION; CELL PROLIFERATION; DRUG SCREENING; DRUG SYNTHESIS; ENDOTHELIUM CELL; ENZYME ACTIVITY; HUMAN; HUMAN CELL; PROTEIN PHOSPHORYLATION;

ANGIOGENESIS INHIBITORS; CELL MOVEMENT; CELL PROLIFERATION; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIAL CELLS; HUMANS; MOLECULAR STRUCTURE; NEOVASCULARIZATION, PHYSIOLOGIC; NIACINAMIDE; SIGNAL TRANSDUCTION; STRUCTURE-ACTIVITY RELATIONSHIP; VASCULAR ENDOTHELIAL GROWTH FACTORS;

EID: 84875229055     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2013.01.125     Document Type: Article

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