The effects of temporal unpredictability in anticipation of negative events in combat veterans with PTSD

Journal of Affective Disorders

Volumn 146, Issue 3, 2013, Pages 426-432

  Simmons, Alan N ^a,b,d   Flagan, Taru M ^d   Wittmann, Marc ^a,d,e   Strigo, Irina A ^a,b,d   Matthews, Scott C ^a,c,d   Donovan, Heather ^a,b,d   Lohr, James B ^a,b,d   Paulus, Martin P ^a,b,d  

^a VA SAN DIEGO HEALTHCARE SYSTEM   (United States)

^b VA Center of Excellence for Stress and Mental Health (CESAMH)   (United States)

^c Mental Illness Research Education and Clinical Center (MIRECC)   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e UNIVERSITY OF FREIBURG   (Germany)

Author keywords

Anticipation; FMRI; Insula; Posttraumatic stress disorder; Predictability; Time

Indexed keywords

ADULT; ANTICIPATION; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; EMOTION; HUMAN; INSULA; MALE; POSTTRAUMATIC STRESS DISORDER; PREDICTION; PRIORITY JOURNAL; TEMPORAL PREDICTABILITY; VETERAN;

ADULT; ANTICIPATION, PSYCHOLOGICAL; CEREBRAL CORTEX; COMBAT DISORDERS; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; STRESS DISORDERS, POST-TRAUMATIC; TIME FACTORS; VETERANS; YOUNG ADULT;

EID: 84875228522     PISSN: 01650327     EISSN: 15732517     Source Type: Journal    
DOI: 10.1016/j.jad.2012.08.006     Document Type: Article

References (50)

1. American Thoracic Society Dyspnea. Mechanisms, assessment, and management: a consensus statement American Journal of Respiratory and Critical Care Medicine 159 1999 321 340
2. E.B. Blanchard, J. Jones-Alexander, T.C. Buckley, and C.A. Forneris Psychometric properties of the PTSD checklist (PCL) Behaviour Research and Therapy 34 1996 669 673
3. M.J. Bohn, T.F. Babor, and H.R. Kranzler The alcohol-use disorders identification test (audit) - validation of a screening instrument for use in medical settings Journal of Studies on Alcohol 56 1995 423 432
4. J.D. Bremner, M. Vythilingam, E. Vermetten, J. Adil, S. Khan, A. Nazeer, N. Afzal, T. McGlashan, B. Elzinga, G.M. Anderson, G. Heninger, S.M. Southwick, and D.S. Charney Cortisol response to a cognitive stress challenge in posttraumatic stress disorder (PTSD) related to childhood abuse Psychoneuroendocrinology 28 2003 733 750
5. C.H. Brunia, B.M. de Jong, M.M. van den Berg-Lenssen, and A.M. Paans Visual feedback about time estimation is related to a right hemisphere activation measured by PET Experimental Brain Research 130 2000 328 337
6. A.D. Craig Emotional moments across time: a possible neural basis for time perception in the anterior insula Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences 364 2009 1933 1942
7. Delis, D.C., Kaplan, E., Kramer, J.H., 2001. Delis-Kaplan Executive Function System. The Psychological Corporation.
8. A. Etkin, and T.D. Wager Functional neuroimaging of anxiety: a meta-analysis of emotional processing in PTSD, social anxiety disorder, and specific phobia The American Journal of Psychiatry 164 2007 1476 1488
9. J.L. Falk, and D. Bindra Judgment of time as a function of serial position and stress Journal of Experimental Psychology 47 1954 279 282
10. J. Fan, R. Kolster, J. Ghajar, M. Suh, R.T. Knight, R. Sarkar, and B.D. McCandliss Response anticipation and response conflict: an event-related potential and functional magnetic resonance imaging study Journal of Neuroscience 27 2007 2272 2282
11. J.R. Fann, C.H. Bombardier, S. Dikmen, P. Esselman, C.A. Warms, E. Pelzer, H. Rau, and N. Temkin Validity of the patient health questionnaire-9 in assessing depression following traumatic brain injury The Journal of Head Trauma Rehabilitation 20 2005 501 511
12. M.B. First, R.L. Spitzer, M. Gibbon, and J.B.W. Williams Structured Clinical Interview for DSM-IV Axis I Disorders - Clinician Version (SCID-1) 1997 American Psychiatric Press, Inc. Washington, D.C
13. E.B. Foa, R. Zinbarg, and B.O. Rothbaum Uncontrollability and unpredictability in post-traumatic stress disorder: an animal model Psychological Bulletin 112 1992 218 238
14. T. Gan, N. Wang, Z. Zhang, H. Li, and Y.J. Luo Emotional influences on time perception: evidence from event-related potentials Neuroreport 20 2009 839 843
15. C. Grillon Models and mechanisms of anxiety: evidence from startle studies Psychopharmacology 199 2008 421 437
16. C. Grillon, S. Lissek, S. Rabin, D. McDowell, S. Dvir, and D.S. Pine Increased anxiety during anticipation of unpredictable but not predictable aversive stimuli as a psychophysiologic marker of panic disorder The American Journal of Psychiatry 165 2008 898 904
17. C. Grillon, D.S. Pine, S. Lissek, S. Rabin, O. Bonne, and M. Vythilingam Increased anxiety during anticipation of unpredictable aversive stimuli in posttraumatic stress disorder but not in generalized anxiety disorder Biological Psychiatry 66 2009 47 53
18. D.W. Grupe, and J.B. Nitschke Uncertainty is associated with biased expectancies and heightened responses to aversion. Emotion. Washington, D.C. 11 2011 413 424
19. P. Hancock, and J. Weaver On time distortion under stress Theoretical Issues in Ergonomics Science 6 2005 193 211
20. D. Harrington, J. Malec, K. Cicerone, and H. Katz Current perceptions of rehabilitation professionals towards mild traumatic brain injury Archives of Physical Medicine and Rehabilitation 74 1993 579
21. L.A. King, D.W. King, D.S. Vogt, J. Knight, and R.E. Samper Deployment risk and resilience inventory: a collection of measures for studying deployment-related experiences of military personnel and veterans Military Psychology 18 2006 89 120
22. J.I. Lake, and K.S. Labar Unpredictability and uncertainty in anxiety: a new direction for emotional timing research Frontiers in Integrative Neuroscience 5 2011 55
23. P.A. Lewis, and R.C. Miall Brain activation patterns during measurement of sub- and supra-second intervals Neuropsychologia 41 2003 1583 1592
24. K.L. Lovero, A.N. Simmons, J.L. Aron, and M.P. Paulus Anterior insular cortex anticipates impending stimulus significance NeuroImage 45 2009 976 983
25. W.H. Meck, and C.J. Macdonald Amygdala inactivation reverses fear's ability to impair divided attention and make time stand still Behavioral Neuroscience 121 2007 707 720
26. N. Mella, L. Conty, and V. Pouthas The role of physiological arousal in time perception: psychophysiological evidence from an emotion regulation paradigm Brain and Cognition 75 2011 182 187
27. B. Morillon, C.A. Kell, and A.L. Giraud Three stages and four neural systems in time estimation Journal of Neuroscience 29 2009 14803 14811
28. H.E. Nelson, and J. Willison National Adult Reading Test (NART): Test Manual 1991 Windsor UK: NFER
29. J.B. Nitschke, I. Sarinopoulos, K.L. Mackiewicz, H.S. Schaefer, and R.J. Davidson Functional neuroanatomy of aversion and its anticipation NeuroImage 29 2006 106 116
30. M.P. Paulus, and M.B. Stein An insular view of anxiety Biological Psychiatry 60 2006 383 387
31. I. Sarinopoulos, D.W. Grupe, K.L. Mackiewicz, J.D. Herrington, M. Lor, E.E. Steege, and J.B. Nitschke Uncertainty during anticipation modulates neural responses to aversion in human insula and amygdala Cerebral Cortex 20 2010 929 940
32. A. Simmons, S.C. Matthews, J.S. Feinstein, C. Hitchcock, M.P. Paulus, and M.B. Stein Anxiety vulnerability is associated with altered anterior cingulate response to an affective appraisal task Neuroreport 19 2008 1033 1037
33. A. Simmons, S.C. Matthews, M.P. Paulus, and M.B. Stein Intolerance of uncertainty correlates with insula activation during affective ambiguity Neuroscience Letters 430 2008 92 97
34. A. Simmons, S.C. Matthews, M.B. Stein, and M.P. Paulus Anticipation of emotionally aversive visual stimuli activates right insula Neuroreport 15 2004 2261 2265
35. A. Simmons, I. Strigo, S.C. Matthews, M.P. Paulus, and M.B. Stein Anticipation of aversive visual stimuli is associated with increased insula activation in anxiety-prone subjects Biological Psychiatry 60 2006 402 409
36. A. Simmons, I.A. Strigo, S.C. Matthews, M.P. Paulus, and M.B. Stein Initial evidence of a failure to activate right anterior insula during affective set shifting in posttraumatic stress disorder Psychosomatic Medicine 71 2009 373 377
37. A.N. Simmons, S. Fitzpatrick, I.A. Strigo, E.G. Potterat, D.C. Johnson, S.C. Matthews, K.F. Van Orden, J.L. Swain, and M.P. Paulus Altered insula activation in anticipation of changing emotional states: neural mechanisms underlying cognitive flexibility in special operations forces personnel Neuroreport 23 2012 234 239
38. A.N. Simmons, and S.C. Matthews Neural circuitry of PTSD with or without mild traumatic brain injury: a meta-analysis Neuropharmacology 62 2012 598 606
39. A.N. Simmons, M.P. Paulus, S.R. Thorp, S.C. Matthews, S.B. Norman, and M.B. Stein Functional activation and neural networks in women with posttraumatic stress disorder related to intimate partner violence Biological Psychiatry 64 2008 681 690
40. A.N. Simmons, M.B. Stein, I.A. Strigo, E. Arce, C. Hitchcock, and M.P. Paulus Anxiety positive subjects show altered processing in the anterior insula during anticipation of negative stimuli Human Brain Mapping 32 2011 1836 1846
41. A. Smith, E. Taylor, K. Lidzba, and K. Rubia A right hemispheric frontocerebellar network for time discrimination of several hundreds of milliseconds NeuroImage 20 2003 344 350
42. I.A. Strigo, A.N. Simmons, S.C. Matthews, A.D. Craig, and M.P. Paulus Association of major depressive disorder with altered functional brain response during anticipation and processing of heat pain Archives of General Psychiatry 65 2008 1275 1284
43. I.A. Strigo, A.N. Simmons, S.C. Matthews, E.M. Grimes, C.B. Allard, L.E. Reinhardt, M.P. Paulus, and M.B. Stein Neural correlates of altered pain response in women with posttraumatic stress disorder from intimate partner violence Biological Psychiatry 68 2010 442 450
44. A. von Leupoldt, T. Sommer, S. Kegat, H.J. Baumann, H. Klose, B. Dahme, and C. Buchel The unpleasantness of perceived dyspnea is processed in the anterior insula and amygdala American Journal of Respiratory and Critical Care Medicine 177 2008 1026 1032
45. M. Wiener, P. Turkeltaub, and H.B. Coslett The image of time: a voxel-wise meta-analysis NeuroImage 49 2010 1728 1740
46. M. Wittmann The inner experience of time Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences 364 2009 1955 1967
47. M. Wittmann, K.L. Lovero, S.D. Lane, and M.P. Paulus Now or later? Striatum and insula activation to immediate versus delayed rewards Journal of Neuroscience, Psychology, and Economics 3 2010 15 26
48. M. Wittmann, and V. van Wassenhove The experience of time: neural mechanisms and the interplay of emotion, cognition and embodiment Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences 364 2009 1809 1813
49. M. Wittmann, V. van Wassenhove, A.D. Craig, and M.P. Paulus The neural substrates of subjective time dilation Frontiers in Human Neuroscience 4 2010 2
50. M.J. Zvolensky, C.W. Lejuez, and G.H. Eifert Prediction and control: operational definitions for the experimental analysis of anxiety Behaviour Research and Therapy 38 2000 653 663