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Bioorganic and Medicinal Chemistry Letters

Volumn 23, Issue 7, 2013, Pages 2052-2055

Potential CRF1R PET imaging agents: 1-Fluoroalkylsubstituted 5-halo-3-(arylamino)pyrazin-2(1H)-ones

(14) Denhart, Derek J a Zuev, Dmitry a Ditta, Jonathan L a Hartz, Richard A a Ahuja, Vijay T a Mattson, Ronald J a Huang, Hong a Mattson, Gail K a Zueva, Larisa b Nielsen, Julia M b Kozlowski, Edward S a Lodge, Nicholas J a Bronson, Joanne J a MacOr, John E a

a BRISTOL MYERS SQUIBB (United States)

b Spectrix Analytical Services (United States)

Author keywords

CRF; Depression; Fluoroalkyl; PET; Pyrazinones

Indexed keywords

CORTICOTROPIN RELEASING FACTOR ANTAGONIST; CORTICOTROPIN RELEASING FACTOR RECEPTOR 1; PYRAZINE DERIVATIVE; CORTICOTROPIN RELEASING FACTOR RECEPTOR; DIAGNOSTIC AGENT;

ARTICLE; BINDING AFFINITY; IC 50; IN VIVO STUDY; LIPOPHILICITY; PHYSICAL CHEMISTRY; POSITRON EMISSION TOMOGRAPHY; ANIMAL; BRAIN; CHEMICAL STRUCTURE; CHEMISTRY; DRUG ANTAGONISM; HUMAN; RAT;

ANIMALS; BRAIN; HUMANS; MOLECULAR STRUCTURE; POSITRON-EMISSION TOMOGRAPHY; PYRAZINES; RATS; RECEPTORS, CORTICOTROPIN-RELEASING HORMONE;

EID: 84875227375 PISSN: 0960894X EISSN: 14643405 Source Type: Journal
DOI: 10.1016/j.bmcl.2013.02.009 Document Type: Article

Times cited : (4)

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