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Volumn 28, Issue 2, 2001, Pages 187-195

Synthesis and characterization of fluorinated and iodinated pyrrolopyrimidines as PET/SPECT ligands for the CRF1 receptor

(7) Martarello, Laurent a Kilts, Clinton D a Ely, Timothy a Owens, Michael J a Nemeroff, Charles B a Camp, Mel a Goodman, Mark M a

a EMORY UNIVERSITY SCHOOL OF MEDICINE (United States)

Author keywords

CRF receptor; Fluorine 18; Iodine 123; Radiolabeling

Indexed keywords

BUTYL[2,5 DIMETHYL 7 (4 IODO 2,6 DIMETHYLPHENYL) 7H PYRROLO[2,3 D]PYRIMIDIN 4 YL]ETHYLAMINE I 123; CORTICOTROPIN RELEASING FACTOR RECEPTOR; FLUOROBUTYL[2,5 DIMETHYL 7 (2,4,6 TRIMETHYLPHENYL) 7H PYRROLO[2,3 D]PYRIMIDIN 4 YL]ETHYLAMINE F 18; LIGAND; TRACER; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BLOOD BRAIN BARRIER; CHEMICAL REACTION; CONTROLLED STUDY; HYPOPHYSIS; ISOTOPE LABELING; MALE; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; RADIOACTIVITY; RADIOCHEMISTRY; RAT; RECEPTOR BINDING; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; SYNTHESIS; TISSUE DISTRIBUTION;

ANIMALS; BRAIN; FLUORINE RADIOISOTOPES; IODINE RADIOISOTOPES; LIGANDS; MALE; PITUITARY GLAND; PYRIMIDINES; PYRROLES; RADIOLIGAND ASSAY; RADIOPHARMACEUTICALS; RATS; RATS, INBRED F344; RATS, SPRAGUE-DAWLEY; RECEPTORS, CORTICOTROPIN-RELEASING HORMONE; TISSUE DISTRIBUTION; TOMOGRAPHY, EMISSION-COMPUTED; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON;

EID: 0035057666 PISSN: 09698051 EISSN: None Source Type: Journal
DOI: 10.1016/S0969-8051(00)00199-2 Document Type: Article

Times cited : (27)

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