Clamp loading, unloading and intrinsic stability of the PCNA, β and gp45 sliding clamps of human, E. coli and T4 replicases

Genes to Cells

Volumn 1, Issue 1, 1996, Pages 101-113

  Yao, Nina ^a   Turner, Jennifer ^a   Kelman, Zvi ^a,c   Todd Stukenberg, P ^b,d   Dean, Frank ^a   Shechter, David ^a   Pan, Zhen Qiang ^b   Hurwitz, Jerard ^b   O'Donnell, Mike ^a  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

^b MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^c JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLINE; DNA; DNA DIRECTED DNA POLYMERASE; DNA REPLICASE; GENE 45 PROTEIN, ENTEROBACTERIA PHAGE T4; TRANSACTIVATOR PROTEIN; VIRUS PROTEIN;

ARTICLE; BACTERIOPHAGE T4; CHEMISTRY; DNA REPLICATION; ENZYME STABILITY; ESCHERICHIA COLI; HUMAN; IN VITRO STUDY; METABOLISM; PROTEIN CONFORMATION; SOLUTION AND SOLUBILITY;

BACTERIOPHAGE T4; DNA; DNA REPLICATION; DNA-DIRECTED DNA POLYMERASE; ENZYME STABILITY; ESCHERICHIA COLI; HUMANS; PROLIFERATING CELL NUCLEAR ANTIGEN; PROTEIN CONFORMATION; SOLUTIONS; TRANS-ACTIVATORS; VIRAL PROTEINS;

EID: 0029678248     PISSN: 13569597     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2443.1996.07007.x     Document Type: Article

References (13)

1. Burgers, P.M.J. (1991) Saccharomyces cerevisiae Replication Factor C: II. Formation and activity of complexes with the proliferating cell nuclear antigen and with DNA polymerase δ and ∈. J. Biol. Chem. 266, 22698-22706.
2. Burgers, P.M.J. & Yoder, B.L. (1993) ATP-independent loading of the proliferating cell nuclear antigen requires DNA ends. J. Biol. Chem. 268, 19923-19926.
3. Capson, T.L., Benkovic, S.J. & Nossal, N.G. (1991) Protein-DNA cross-linking demonstrates stepwise ATP-dependent assembly of the T4 DNA polymerase and its accessory proteins on the primer-template. Cell 65, 249-258.
4. Flores-Rozas, H., Keiman, Z., Dean, F.B., Pan, Z.-Q., Harper, J.W., Elledge, S.J., O'Donnell, M. & Hurwitz, J. (1994) Cdk-interacting protein-1 (Cip1, WAF1) directly binds with proliferating cell nuclear antigen and inhibits DNA replication catalyzed by polymerase 6 holoenzyme. Proc. Natl Acad. Sci. USA 91, 8655-8659.
5. Frappier, L., and O'Donnell, M. (1991) Overproduction, purification, and characterization of EBNA-1, the origin binding protein of Epstein-Barr virus. J. Biol. Chem. 266, 7819-7826.
6. Gogol, E.P., Young, M.C., Kubasek, W.L., Jarvis, T.C. & von Hippel, P.H. (1992) Cryoelectron microscopic visualization of functional subassemblies of the bacteriophage T4 DNA replication complex. J. Mol. Biol. 224, 395-412.
7. Hacker, K.J., and Alberts, B.M. (1994a) The rapid dissociation of the T4 DNA polymerase holoenzyme when stopped by a DNA hairpin helix. J. Biol. Chem. 269, 24221-24228.
8. Hacker, K.J. & Alberts, B.M. (1994b) The slow dissociation of the T4 DNA polymerase. holoenzyme when stalled by nucleotide omission. An indication of a highly processive enzyme. J. Biol. Chem. 269, 24209-24220.
9. Herendeen, D.R., Kassavetis, G.A., Barry, J., Alberts, B.M. & Geiduschek, E.P. (1989) Enhancement of bacteriophage T4 late transcription by components of the T4 DNA replication apparatus. Science 245, 952-958.
10. Jarvis, T.C., Paul, L.S. & von Hippel, P.H. (1989) Structural and enzymatic studies of the T4 DNA replication system. J. Biol. Chem. 264, 12709-12716.
11. Waga, S., Hannon, G.J., Beach, D. & Stillman, B. (1994) The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA. Nature 369, 574-578.
12. Xiong, Y., Zhang, H. & Beach, D. (1992) D type cyclins associate with multiple protein kinases and the DNA replication and repair factor PCNA. Cell 71, 505-514.
13. Zhang, P., Zhang, S.-J., Zhang, Z., Woessner, J.F. & Lee, M.Y.W.T. (1995) Expression and physiochemical characterization of human proliferating cell nuclear antigen. Biochemistry 34, 10703-10712.