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Bioorganic and Medicinal Chemistry

Volumn 21, Issue 7, 2013, Pages 1621-1627

Novel leucine ureido derivatives as inhibitors of aminopeptidase N (APN)

(6) Ma, Chunhua a Jin, Kang a Cao, Jiangying a Zhang, Lei a Li, Xiaoguang a Xu, Wenfang a

a SHANDONG UNIVERSITY (China)

Author keywords

Aminopeptidase N; Inhibitors; Leucine ureido derivatives; Synthesis

Indexed keywords

2 [3 (2 BROMOBENZYL)UREIDO] 4 METHYL PENTANOIC ACID HYDROXYAMIDE; 2 [3 (2 BROMOPHENYL)UREIDO] 4 METHYL PENTANOIC ACID HYDROXYAMIDE; 2 [3 (2 CHLOROBENZYL)UREIDO] 4 METHYL PENTANOIC ACID HYDROXYAMIDE; 2 [3 (2 CHLOROPHENYL)UREIDO] 4 METHYL PENTANOIC ACID HYDROXYAMIDE; 2 [3 (2 FLUOROBENZYL)UREIDO] 4 METHYL PENTANOIC ACID HYDROXYAMIDE; 2 [3 (2 FLUOROPHENYL)UREIDO] 4 METHYL PENTANOIC ACID HYDROXYAMIDE; 2 [3 (2 HYDROXYPHENYL)UREIDO] 4 METHYL PENTANOIC ACID HYDROXYAMIDE; 2 [3 (2 METHOXYPHENYL)UREIDO] 4 METHYL PENTANOIC ACID HYDROXYAMIDE; 2 [3 (3 BROMOPHENYL)UREIDO] 4 METHYL PENTANOIC ACID HYDROXYAMIDE; 2 [3 (3 CHLOROBENZYL)UREIDO] 4 METHYL PENTANOIC ACID HYDROXYAMIDE; 2 [3 (3 CHLOROPHENYL)UREIDO] 4 METHYL PENTANOIC ACID HYDROXYAMIDE; 2 [3 (3 FLUOROPHENYL)UREIDO] 4 METHYL PENTANOIC ACID HYDROXYAMIDE; 2 [3 (3 HYDROXYPHENYL)UREIDO] 4 METHYL PENTANOIC ACID HYDROXYAMIDE; 2 [3 (3 METHOXYPHENYL)UREIDO] 4 METHYL PENTANOIC ACID HYDROXYAMIDE; 4 METHYL 2 (3 M TOLYL UREIDO)PENTANOIC ACID PENTANOIC ACID HYDROXYAMIDE; 4 METHYL 2 (3 O TOLYL UREIDO)PENTANOIC ACID PENTANOIC ACID HYDROXYAMIDE; 4 METHYL 2 [3 (2 METHYLBENZYL)UREIDO]PENTANOIC ACID HYDROXYAMIDE; 4 METHYL 2 [3 (2 TRIFLUOROMETHYL PHENYL)UREIDO]PENTANOIC ACID HYDROXYAMIDE; 4 METHYL 2 [3 (3 METHYLBENZYL)UREIDO]PENTANOIC ACID HYDROXYAMIDE; 4 METHYL 2 [3 (3 TRIFLUOROMETHYL PHENYL)UREIDO]PENTANOIC ACID HYDROXYAMIDE; BESTATIN; HISTONE DEACETYLASE 1; HISTONE DEACETYLASE 3; HISTONE DEACETYLASE 5; HISTONE DEACETYLASE 8; LEUCINE UREIDO DERIVATIVE; MICROSOMAL AMINOPEPTIDASE; PEPTIDE HYDROLASE INHIBITOR; UNCLASSIFIED DRUG; VORINOSTAT;

ARTICLE; CELL ASSAY; CHEMICAL MODIFICATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG DESIGN; DRUG POTENCY; DRUG SYNTHESIS; ENZYME INHIBITION; HUMAN; HUMAN CELL; IC 50; STRUCTURE ACTIVITY RELATION;

ANIMALS; ANTIGENS, CD13; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; DRUG DESIGN; HUMANS; INHIBITORY CONCENTRATION 50; LEUCINE; MOLECULAR DOCKING SIMULATION; NEOPLASMS; PROTEASE INHIBITORS; SWINE;

EID: 84875218168 PISSN: 09680896 EISSN: 14643391 Source Type: Journal
DOI: 10.1016/j.bmc.2013.01.068 Document Type: Article

Times cited : (15)

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