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Volumn 38, Issue 5, 2013, Pages 802-816

Candidate gene studies of a promising intermediate phenotype: Failure to replicate

Author keywords

candidate gene; D amphetamine; genetic association; intermediate phenotype; replication

Indexed keywords

AMPHETAMINE; DNA; PLACEBO;

EID: 84875216334     PISSN: 0893133X     EISSN: 1740634X     Source Type: Journal    
DOI: 10.1038/npp.2012.245     Document Type: Article
Times cited : (62)

References (60)
  • 1
    • 0030297902 scopus 로고    scopus 로고
    • Quantitative trait loci contributing to phencyclidine-induced and amphetamine-induced locomotor behavior in inbred mice
    • Alexander RC, Wright R, Freed W (1996). Quantitative trait loci contributing to phencyclidine-induced and amphetamine-induced locomotor behavior in inbred mice. Neuropsychopharmacology 15: 484-490.
    • (1996) Neuropsychopharmacology , vol.15 , pp. 484-490
    • Alexander, R.C.1    Wright, R.2    Freed, W.3
  • 3
    • 27644554698 scopus 로고    scopus 로고
    • Framework for a fully powered risk engine
    • Anonymous
    • Anonymous (2005). Framework for a fully powered risk engine. Nat Genet 37: 1153.
    • (2005) Nat Genet , vol.37 , pp. 1153
  • 5
    • 80051817533 scopus 로고    scopus 로고
    • Neural correlates of interspecies perspective taking in the post-Mortem Atlantic Salmon: An argument for proper multiple comparisons correction
    • Bennett C, Baird AA, Miller MB, Wolford GL (2011). Neural correlates of interspecies perspective taking in the post-Mortem Atlantic Salmon: an argument for proper multiple comparisons correction. J Serendipitous Unexpected Results 1: 1-5.
    • (2011) J Serendipitous Unexpected Results , vol.1 , pp. 1-5
    • Bennett, C.1    Baird, A.A.2    Miller, M.B.3    Wolford, G.L.4
  • 7
    • 78649548051 scopus 로고    scopus 로고
    • Poor replication of candidate genes for major depressive disorder using genome-wide association data
    • Bosker FJ, Hartman CA, Nolte IM, Prins BP, Terpstra P, Posthuma D et al (2011). Poor replication of candidate genes for major depressive disorder using genome-wide association data. Mol Psychiatry 16: 516-532.
    • (2011) Mol Psychiatry , vol.16 , pp. 516-532
    • Bosker, F.J.1    Hartman, C.A.2    Nolte, I.M.3    Prins, B.P.4    Terpstra, P.5    Posthuma, D.6
  • 8
    • 0021836865 scopus 로고
    • 'Hangover' effects the morning after marijuana smoking
    • Chait L, Fischman MW, Schuster CR (1985). 'Hangover' effects the morning after marijuana smoking. Drug Alcohol Depend 15: 229-238.
    • (1985) Drug Alcohol Depend , vol.15 , pp. 229-238
    • Chait, L.1    Fischman, M.W.2    Schuster, C.R.3
  • 10
    • 77949756362 scopus 로고    scopus 로고
    • Genome-wide association studies in pharmacogenomics
    • Daly AK (2010). Genome-wide association studies in pharmacogenomics. Nat Rev Genet 11: 241-246.
    • (2010) Nat Rev Genet , vol.11 , pp. 241-246
    • Daly, A.K.1
  • 11
    • 34248215695 scopus 로고    scopus 로고
    • Norepinephrine transporter gene variation modulates acute response to D-amphetamine
    • Dlugos A, Freitag C, Hohoff C, McDonald J, Cook E, Deckert J et al (2007). Norepinephrine transporter gene variation modulates acute response to D-amphetamine. Biol Psychiatry 61: 1296-1305.
    • (2007) Biol Psychiatry , vol.61 , pp. 1296-1305
    • Dlugos, A.1    Freitag, C.2    Hohoff, C.3    McDonald, J.4    Cook, E.5    Deckert, J.6
  • 13
    • 75749113226 scopus 로고    scopus 로고
    • More aroused, less fatigued: Fatty acid amide hydrolase gene polymorphisms influence acute response to amphetamine
    • Dlugos AM, Hamidovic A, Hodgkinson CA, Goldman D, Palmer AA, de Wit H (2010). More aroused, less fatigued: fatty acid amide hydrolase gene polymorphisms influence acute response to amphetamine. Neuropsychopharmacology 35: 613-622.
    • (2010) Neuropsychopharmacology , vol.35 , pp. 613-622
    • Dlugos, A.M.1    Hamidovic, A.2    Hodgkinson, C.A.3    Goldman, D.4    Palmer, A.A.5    De Wit, H.6
  • 14
    • 70349561331 scopus 로고    scopus 로고
    • Further evidence of association between amphetamine response and SLC6A2 gene variants
    • Dlugos AM, Hamidovic A, Palmer AA, Wit H (2009). Further evidence of association between amphetamine response and SLC6A2 gene variants. Psychopharmacology (Berl) 206: 501-511.
    • (2009) Psychopharmacology (Berl , vol.206 , pp. 501-511
    • Dlugos, A.M.1    Hamidovic, A.2    Palmer, A.A.3    Wit, H.4
  • 15
    • 84975742565 scopus 로고    scopus 로고
    • A map of human genome variation from population-scale sequencing
    • Durbin R, Abecasis G, Altshuler D, Auton A, Brooks L, Gibbs R et al (2010). A map of human genome variation from population-scale sequencing. Nature 467: 1061-1073.
    • (2010) Nature , vol.467 , pp. 1061-1073
    • Durbin, R.1    Abecasis, G.2    Altshuler, D.3    Auton, A.4    Brooks, L.5    Gibbs, R.6
  • 16
    • 80052322958 scopus 로고    scopus 로고
    • Trans-eQTLs reveal that independent genetic variants associated with a complex phenotype converge on intermediate genes, with a major role for the HLA
    • Fehrmann RSN, Jansen RC, Veldink JH, Westra H-J, Arends D, Bonder MJ et al (2011). Trans-eQTLs reveal that independent genetic variants associated with a complex phenotype converge on intermediate genes, with a major role for the HLA. Plos Genet 7: e1002197.
    • (2011) Plos Genet , vol.7
    • Rsn, F.1    Jansen, R.C.2    Veldink, J.H.3    Westra, H.-J.4    Arends, D.5    Bonder, M.J.6
  • 17
    • 33748948061 scopus 로고    scopus 로고
    • An association study of the brain-derived neurotrophic factor Val66Met polymorphism and amphetamine response
    • Flanagin B, Cook Jr E, de Wit H (2006). An association study of the brain-derived neurotrophic factor Val66Met polymorphism and amphetamine response. Am J Med Genet B 141: 576-583.
    • (2006) Am J Med Genet B , vol.141 , pp. 576-583
    • Flanagin, B.1    Cook Jr., E.2    De Wit, H.3
  • 19
  • 20
    • 84875480197 scopus 로고    scopus 로고
    • Enrichment of cis-regulatory gene expression SNPs and methylation quantitative trait loci among bipolar disorder susceptibility variants
    • Gamazon ER, Badner JA, Cheng L, Zhang C, Zhang D, Cox NJ et al (2012). Enrichment of cis-regulatory gene expression SNPs and methylation quantitative trait loci among bipolar disorder susceptibility variants. Mol Psychiatryhttp://www.blackwellpublishing. com/pdf/G2B-Association-Studies.pdf.
    • (2012) Mol Psychiatry
    • Gamazon, E.R.1    Badner, J.A.2    Cheng, L.3    Zhang, C.4    Zhang, D.5    Cox, N.J.6
  • 21
    • 37249087373 scopus 로고    scopus 로고
    • Deconstruction of vulnerability to complex diseases: Enhanced effect sizes and power of intermediate phenotypes
    • Goldman D, Ducci F (2007). Deconstruction of vulnerability to complex diseases: enhanced effect sizes and power of intermediate phenotypes. ScientificWorldJournal 7: 124-130.
    • (2007) ScientificWorldJournal , vol.7 , pp. 124-130
    • Goldman, D.1    Ducci, F.2
  • 22
    • 0038823525 scopus 로고    scopus 로고
    • The endophenotype concept in psychiatry: Etymology and strategic intentions
    • Gottesman II, Gould TD (2003). The endophenotype concept in psychiatry: etymology and strategic intentions. Am J Psychiatry 160: 636-645.
    • (2003) Am J Psychiatry , vol.160 , pp. 636-645
    • Gottesman, I.I.1    Gould, T.D.2
  • 23
    • 0031021297 scopus 로고    scopus 로고
    • Quantitative trait loci affecting methamphetamine responses in BXD recombinant inbred mouse strains
    • Grisel JE, Belknap JK, O'Toole LA, Helms ML, Wenger CD, Crabbe JC (1997). Quantitative trait loci affecting methamphetamine responses in BXD recombinant inbred mouse strains. J Neurosci 17: 745-754.
    • (1997) J Neurosci , vol.17 , pp. 745-754
    • Grisel, J.E.1    Belknap, J.K.2    O'Toole, L.A.3    Helms, M.L.4    Wenger, C.D.5    Crabbe, J.C.6
  • 24
    • 77953809083 scopus 로고    scopus 로고
    • Catechol-Omethyltransferase val158met genotype modulates sustained attention in both the drug-free state and in response to amphetamine
    • Hamidovic A, Dlugos A, Palmer A, de Wit H (2010a). Catechol- Omethyltransferase val158met genotype modulates sustained attention in both the drug-free state and in response to amphetamine. Psychiatr Genet 20: 85.
    • (2010) Psychiatr Genet , vol.20 , pp. 85
    • Hamidovic, A.1    Dlugos, A.2    Palmer, A.3    De Wit, H.4
  • 25
    • 77949265506 scopus 로고    scopus 로고
    • Polymorphisms in dopamine transporter (SLC6A3) are associated with stimulant effects of d-amphetamine: An exploratory pharmacogenetic study using healthy volunteers
    • Hamidovic A, Dlugos A, Palmer AA, de Wit H (2010b). Polymorphisms in dopamine transporter (SLC6A3) are associated with stimulant effects of d-amphetamine: an exploratory pharmacogenetic study using healthy volunteers. Behav Genet 40: 255-261.
    • (2010) Behav Genet , vol.40 , pp. 255-261
    • Hamidovic, A.1    Dlugos, A.2    Palmer, A.A.3    De Wit, H.4
  • 26
    • 72549113599 scopus 로고    scopus 로고
    • Evaluation of genetic variability in the dopamine receptor D2 in relation to behavioral inhibition and impulsivity/sensation seeking: An exploratory study with d-amphetamine in healthy participants
    • Hamidovic A, Dlugos A, Skol A, Palmer AA, de Wit H (2009). Evaluation of genetic variability in the dopamine receptor D2 in relation to behavioral inhibition and impulsivity/sensation seeking: an exploratory study with d-amphetamine in healthy participants. Exp Clin Psychopharmacol 17: 374-383.
    • (2009) Exp Clin Psychopharmacol , vol.17 , pp. 374-383
    • Hamidovic, A.1    Dlugos, A.2    Skol, A.3    Palmer, A.A.4    De Wit, H.5
  • 27
    • 84865457476 scopus 로고    scopus 로고
    • Genome-wide association study of d-amphetamine response in healthy volunteers identifies putative associations, including cadherin 13 (CDH13
    • Hart AB, Engelhardt BE, Wardle MC, Sokoloff G, Stephens M, de Wit H et al (2012). Genome-wide association study of d-amphetamine response in healthy volunteers identifies putative associations, including cadherin 13 (CDH13). PLoS ONE 7: e42646.
    • (2012) PLoS ONE , vol.7
    • Hart, A.B.1    Engelhardt, B.E.2    Wardle, M.C.3    Sokoloff, G.4    Stephens, M.5    De Wit, H.6
  • 28
    • 84856676280 scopus 로고    scopus 로고
    • Editorial policy on candidate gene association and candidate gene-by-environment interaction studies of complex traits
    • Hewitt JK (2012). Editorial policy on candidate gene association and candidate gene-by-environment interaction studies of complex traits. Behav Genet 42: 1-2.
    • (2012) Behav Genet , vol.42 , pp. 1-2
    • Hewitt, J.K.1
  • 31
    • 51749102111 scopus 로고    scopus 로고
    • Addictions biology: Haplotype-based analysis for 130 candidate genes on a single array
    • Hodgkinson CA, Yuan Q, Xu K, Shen P-H, Heinz E, Lobos EA et al (2008). Addictions biology: haplotype-based analysis for 130 candidate genes on a single array. Alcohol Alcohol 43: 505-515.
    • (2008) Alcohol Alcohol , vol.43 , pp. 505-515
    • Hodgkinson, C.A.1    Yuan, Q.2    Xu, K.3    Shen, P.-H.4    Heinz, E.5    Lobos, E.A.6
  • 32
    • 27644583300 scopus 로고    scopus 로고
    • Interindividual variation in anxiety response to amphetamine: Possible role for adenosine A 2Areceptor gene variants
    • Hohoff C, Mcdonald JM, Baune BT, Cook EH, Deckert J, de Wit H (2005). Interindividual variation in anxiety response to amphetamine: possible role for adenosine A 2Areceptor gene variants. Am J Med Genet 139B: 42-44.
    • (2005) Am J Med Genet , vol.139 B , pp. 42-44
    • Hohoff, C.1    McDonald, J.M.2    Baune, B.T.3    Cook, E.H.4    Deckert, J.5    De Wit, H.6
  • 33
    • 67651222400 scopus 로고    scopus 로고
    • A flexible and accurate genotype imputation method for the next generation of genomewide association studies
    • Howie BN, Donnelly P, Marchini J (2009). A flexible and accurate genotype imputation method for the next generation of genomewide association studies. Plos Genet 5: e1000529.
    • (2009) Plos Genet , vol.5
    • Howie, B.N.1    Donnelly, P.2    Marchini, J.3
  • 34
    • 0019130292 scopus 로고
    • Drug preference and mood in humans: Diazepam
    • Johanson C, Uhlenhuth E (1980). Drug preference and mood in humans: diazepam. Psychopharmacology (Berl) 71: 269-273.
    • (1980) Psychopharmacology (Berl , vol.71 , pp. 269-273
    • Johanson, C.1    Uhlenhuth, E.2
  • 35
    • 34248993332 scopus 로고    scopus 로고
    • Dopamine transporter 3'-UTR VNTR genotype and ADHD: A pharmaco-behavioural genetic study with methylphenidate
    • Joober R, Grizenko N, Sengupta S, Amor LB, Schmitz N, Schwartz G et al (2007). Dopamine transporter 3'-UTR VNTR genotype and ADHD: a pharmaco-behavioural genetic study with methylphenidate. Neuropsychopharmacology 32: 1370-1376.
    • (2007) Neuropsychopharmacology , vol.32 , pp. 1370-1376
    • Joober, R.1    Grizenko, N.2    Sengupta, S.3    Amor, L.B.4    Schmitz, N.5    Schwartz, G.6
  • 38
    • 0021414449 scopus 로고
    • On the ability to inhibit simple and choice reaction time responses: A model and a method
    • Logan G, Cowan W, Davis K (1984). On the ability to inhibit simple and choice reaction time responses: a model and a method. J Exp Psychol 10: 276-291.
    • (1984) J Exp Psychol , vol.10 , pp. 276-291
    • Logan, G.1    Cowan, W.2    Davis, K.3
  • 39
    • 13944267955 scopus 로고    scopus 로고
    • Dopamine transporter gene associated with diminished subjective response to amphetamine
    • Lott D, Kim S, Cook E, de Wit H (2005). Dopamine transporter gene associated with diminished subjective response to amphetamine. Neuropsychopharmacology 30: 602-609.
    • (2005) Neuropsychopharmacology , vol.30 , pp. 602-609
    • Lott, D.1    Kim, S.2    Cook, E.3    De Wit, H.4
  • 40
    • 33748554013 scopus 로고    scopus 로고
    • Serotonin transporter genotype and acute subjective response to amphetamine
    • Lott D, Kim S, Cook E Jr, de Wit H (2006). Serotonin transporter genotype and acute subjective response to amphetamine. Amer J Addiction 15: 327-335.
    • (2006) Amer J Addiction , vol.15 , pp. 327-335
    • Lott, D.1    Kim, S.2    Cook Jr., E.3    De Wit, H.4
  • 41
    • 58749100314 scopus 로고    scopus 로고
    • Associations of ADH and ALDH2 gene variation with self report alcohol reactions, consumption and dependence: An integrated analysis
    • Macgregor S, Lind PA, Bucholz KK, Hansell NK, Madden PAF, Richter MM et al (2009). Associations of ADH and ALDH2 gene variation with self report alcohol reactions, consumption and dependence: an integrated analysis. Hum Mol Genet 18: 580-593.
    • (2009) Hum Mol Genet , vol.18 , pp. 580-593
    • MacGregor, S.1    Lind, P.A.2    Bucholz, K.K.3    Hansell, N.K.4    Madden, P.A.F.5    Richter, M.M.6
  • 42
    • 0015026728 scopus 로고
    • Physiologic, subjective, and behavioral effects of amphetamine, methamphetamine, ephedrine, phenmetrazine, and methylphenidate in man
    • Martin W, Sloan J, Sapira J, Jasinski D (1971). Physiologic, subjective, and behavioral effects of amphetamine, methamphetamine, ephedrine, phenmetrazine, and methylphenidate in man. Clin Pharmacol Ther 12: 245-258.
    • (1971) Clin Pharmacol Ther , vol.12 , pp. 245-258
    • Martin, W.1    Sloan, J.2    Sapira, J.3    Jasinski, D.4
  • 43
    • 84861458242 scopus 로고    scopus 로고
    • Meta-analysis indicates that common variants at the DISC1 locus are not associated with schizophrenia
    • Mathieson I, Munafò MR, Flint J (2012). Meta-analysis indicates that common variants at the DISC1 locus are not associated with schizophrenia. Mol Psychiatry 17: 634-641.
    • (2012) Mol Psychiatry , vol.17 , pp. 634-641
    • Mathieson, I.1    Munafò, M.R.2    Flint, J.3
  • 45
    • 41449100841 scopus 로고    scopus 로고
    • Serotonin transporter (5-HTTLPR) genotype and amygdala activation: A meta-analysis
    • Munafò MR, Brown SM, Hariri AR (2008). Serotonin transporter (5-HTTLPR) genotype and amygdala activation: a meta-analysis. Biol Psychiatry 63: 852-857.
    • (2008) Biol Psychiatry , vol.63 , pp. 852-857
    • Munafò, M.R.1    Brown, S.M.2    Hariri, A.R.3
  • 46
    • 34247542196 scopus 로고    scopus 로고
    • Association of the DRD2 gene Taq1A polymorphism and alcoholism: A meta-analysis of case-control studies and evidence of publication bias
    • Munafò MR, Matheson IJ, Flint J (2007). Association of the DRD2 gene Taq1A polymorphism and alcoholism: a meta-analysis of case-control studies and evidence of publication bias. Mol Psychiatry 12: 454-461.
    • (2007) Mol Psychiatry , vol.12 , pp. 454-461
    • Munafò, M.R.1    Matheson, I.J.2    Flint, J.3
  • 47
    • 84875414517 scopus 로고    scopus 로고
    • The effect of the serotonin transporter polymorphism (5-HTTLPR) on amygdala function: A metaanalysis
    • e-pub ahead of print
    • Murphy SE, Norbury R, Godlewska BR, Cowen PJ, Mannie ZM, Harmer CJ et al (2012). The effect of the serotonin transporter polymorphism (5-HTTLPR) on amygdala function: a metaanalysis. Mol Psychiatry (e-pub ahead of print).
    • (2012) Mol Psychiatry
    • Murphy, S.E.1    Norbury, R.2    Godlewska, B.R.3    Cowen, P.J.4    Mannie, Z.M.5    Harmer, C.J.6
  • 48
    • 77951439152 scopus 로고    scopus 로고
    • Trait-associated SNPs are more likely to be eQTLs: Annotation to enhance discovery from GWAS
    • Nicolae DL, Gamazon E, Zhang W, Duan S, Dolan ME, Cox NJ (2010). Trait-associated SNPs are more likely to be eQTLs: annotation to enhance discovery from GWAS. Plos Genet 6: e1000888.
    • (2010) Plos Genet , vol.6
    • Nicolae, D.L.1    Gamazon, E.2    Zhang, W.3    Duan, S.4    Dolan, M.E.5    Cox, N.J.6
  • 49
    • 0019944541 scopus 로고
    • Behavioral, biochemical and neuroendocrine responses to amphetamine in normal twins and 'well-state' bipolar patients
    • Nurnberger J, Gershon ES, Simmons S, Ebert M, Kessler L, Dibble E et al (1982). Behavioral, biochemical and neuroendocrine responses to amphetamine in normal twins and 'well-state' bipolar patients. Psychoneuroendocrinology 7: 163-176.
    • (1982) Psychoneuroendocrinology , vol.7 , pp. 163-176
    • Nurnberger, J.1    Gershon, E.S.2    Simmons, S.3    Ebert, M.4    Kessler, L.5    Dibble, E.6
  • 51
    • 66749120706 scopus 로고    scopus 로고
    • Independence in ROI analysis: Where is the voodoo?
    • Poldrack RA, Mumford JA (2009). Independence in ROI analysis: where is the voodoo? Soc Cogn Affect Neurosci 4: 208-213.
    • (2009) Soc Cogn Affect Neurosci , vol.4 , pp. 208-213
    • Poldrack, R.A.1    Mumford, J.A.2
  • 55
    • 34247642751 scopus 로고    scopus 로고
    • Spurious genetic associations
    • Sullivan PF (2007). Spurious genetic associations. Biol Psychiatry 61: 1121-1126.
    • (2007) Biol Psychiatry , vol.61 , pp. 1121-1126
    • Sullivan, P.F.1
  • 56
    • 33646153300 scopus 로고    scopus 로고
    • Association between the Casein Kinase 1 Epsilon gene region and subjective response to D-amphetamine
    • Veenstra-VanderWeele J, Qaadir A, Palmer AA, Cook EH, de Wit H (2006). Association between the Casein Kinase 1 Epsilon gene region and subjective response to D-amphetamine. Neuropsychopharmacology 31: 1056-1063.
    • (2006) Neuropsychopharmacology , vol.31 , pp. 1056-1063
    • Veenstra-VanderWeele, J.1    Qaadir, A.2    Palmer, A.A.3    Cook, E.H.4    De Wit, H.5
  • 57
    • 24144456193 scopus 로고    scopus 로고
    • Genetic associations of alcohol dehydrogenase with alcohol use disorders and endophenotypes in white college students
    • Wall TL, Shea SH, Luczak SE, Cook TAR, Carr LG (2005). Genetic associations of alcohol dehydrogenase with alcohol use disorders and endophenotypes in white college students. J Abnorm Psychol 114: 456-465.
    • (2005) J Abnorm Psychol , vol.114 , pp. 456-465
    • Wall, T.L.1    Shea, S.H.2    Luczak, S.E.3    Tar, C.4    Carr, L.G.5
  • 58
    • 84875232305 scopus 로고
    • The measurement and appraisal of adult intelligence
    • Wechsler D (1958). The measurement and appraisal of adult intelligence. J Med Educ 33: 706.
    • (1958) J Med Educ , vol.33 , pp. 706
    • Wechsler, D.1
  • 59
    • 0036830157 scopus 로고    scopus 로고
    • Differential subjective effects of d-amphetamine by gender, hormone levels and menstrual cycle phase
    • White TL, Justice AJH, de Wit H (2002). Differential subjective effects of d-amphetamine by gender, hormone levels and menstrual cycle phase. Pharmacology, Biochemistry and Behavior 73: 729-741.
    • (2002) Pharmacology, Biochemistry and Behavior , vol.73 , pp. 729-741
    • White, T.L.1    Justice, A.J.H.2    De Wit, H.3
  • 60
    • 78349238866 scopus 로고    scopus 로고
    • Acute locomotor responses to cocaine in adolescents vs adults from four divergent inbred mouse strains
    • Zombeck JA, Swearingen SP, Rhodes JS (2010). Acute locomotor responses to cocaine in adolescents vs adults from four divergent inbred mouse strains. Genes Brain Behav 9: 892-898.
    • (2010) Genes Brain Behav , vol.9 , pp. 892-898
    • Zombeck, J.A.1    Swearingen, S.P.2    Rhodes, J.S.3


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