Development and assessment of a complete-detoxication strategy for Fuzi (lateral root of Aconitum carmichaeli) and its application in rheumatoid arthritis therapy

Journal of Ethnopharmacology

Volumn 146, Issue 2, 2013, Pages 562-571

  Tong, Peijian ^a,b   Wu, Chengliang ^a   Wang, Xiaofen ^c   Hu, Hongzhou ^d   Jin, Hongting ^a   Li, Changyu ^a   Zhu, Ying ^a   Shan, Letian ^a   Xiao, Luwei ^a  

^a ZHEJIANG CHINESE MEDICAL UNIVERSITY   (China)

^b ZHEJIANG PROVINCIAL PEOPLE'S HOSPITAL   (China)

^c Wenzhou Hospital of Traditional Chinese Medicine   (China)

^d Nanxing Community Health Service Center   (China)

Author keywords

Aconitine; Acute toxicity; Adjuvant arthritis; Decoction; Detoxication; Fuzi

Indexed keywords

ACONITINE; FREUND ADJUVANT; HYPACONITINE; INTERLEUKIN 1; MESACONITINE; TUMOR NECROSIS FACTOR ALPHA;

ACONITE; ACONITUM CARMICHAELI; ACUTE TOXICITY; ADJUVANT ARTHRITIS; ANIMAL EXPERIMENT; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; DRUG ANALYSIS; DRUG DETERMINATION; DRUG DETOXIFICATION; DRUG EFFICACY; DRUG SURVEILLANCE PROGRAM; FEMALE; FOOD INTAKE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IMMUNOLOGICAL PARAMETERS; LD 50; MALE; MEDICINAL PLANT; MOUSE; NONHUMAN; RAT; RHEUMATOID ARTHRITIS; THERAPY EFFECT; TITRIMETRY; TOXICITY TESTING; WISTAR RAT;

ACONITINE; ACONITUM; ANIMALS; ANTI-INFLAMMATORY AGENTS; ARTHRITIS, EXPERIMENTAL; ARTHRITIS, RHEUMATOID; FEMALE; INTERLEUKIN-1; LETHAL DOSE 50; MALE; MEDICINE, CHINESE TRADITIONAL; MICE; NO-OBSERVED-ADVERSE-EFFECT LEVEL; PLANT PREPARATIONS; PLANT ROOTS; RATS; RATS, WISTAR; TUMOR NECROSIS FACTOR-ALPHA;

ACONITUM CARMICHAELI; ANIMALIA; MUS; RATTUS; RATTUS NORVEGICUS;

EID: 84875214189     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2013.01.025     Document Type: Article

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