Single and Combined Inhibition of Tumor Necrosis Factor, Interleukin-1, and RANKL Pathways in Tumor Necrosis Factor-Induced Arthritis: Effects on Synovial Inflammation, Bone Erosion, and Cartilage Destruction

Arthritis and Rheumatism

Volumn 50, Issue 1, 2004, Pages 277-290

  Zwerina, Jochen ^a   Hayer, Silvia ^a   Tohidast Akrad, Makiyeh ^b   Bergmeister, Helga ^a   Redlich, Kurt ^a   Feige, Ulrich ^c   Dunstan, Colin ^c   Kollias, Giorgos ^d   Steiner, Günter ^a   Smolen, Josef ^a   Schett, Georg ^a,e  

^a UNIVERSITY OF VIENNA   (Austria)

^b LUDWIG BOLTZMANN INSTITUTE FOR LUNG VASCULAR RESEARCH   (Austria)

^c AMGEN INC   (United States)

^d BIOMEDICAL SCIENCES RESEARCH CENTER ALEXANDER FLEMING   (Greece)

^e MEDICAL UNIVERSITY OF VIENNA   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

INFLIXIMAB; INTERLEUKIN 1; OSTEOCLAST DIFFERENTIATION FACTOR; OSTEOPROTEGERIN; RECOMBINANT INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; TUMOR NECROSIS FACTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE EROSION; CARTILAGE DEGENERATION; COMBINATION CHEMOTHERAPY; CONTROLLED STUDY; DISEASE MODEL; DRUG EFFECT; DRUG EFFICACY; DRUG INDICATION; HISTOLOGY; MONOTHERAPY; MOUSE; NONHUMAN; OSTEOCLAST; PRIORITY JOURNAL; REMISSION; RHEUMATOID ARTHRITIS; SYNOVITIS; SYNOVIUM;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIRHEUMATIC AGENTS; ARTHRITIS, RHEUMATOID; BONE AND BONES; CARRIER PROTEINS; CARTILAGE; DRUG SYNERGISM; DRUG THERAPY, COMBINATION; GLYCOPROTEINS; HUMANS; IMMUNOGLOBULIN G; INTERLEUKIN 1 RECEPTOR ANTAGONIST PROTEIN; INTERLEUKIN-1; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; OSTEOCLASTS; OSTEOPROTEGERIN; RANK LIGAND; RECEPTOR ACTIVATOR OF NUCLEAR FACTOR-KAPPA B; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RECEPTORS, TUMOR NECROSIS FACTOR; SIALOGLYCOPROTEINS; SYNOVITIS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 9144261181     PISSN: 00043591     EISSN: None     Source Type: Journal    
DOI: 10.1002/art.11487     Document Type: Article

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