Acute toxicity and sub-chronic toxicity of steroidal saponins from Dioscorea zingiberensis C.H.Wright in rodents

Journal of Ethnopharmacology

Volumn 126, Issue 3, 2009, Pages 543-550

  Qin, Yuan ^a   Wu, Xiaohua ^a   Huang, Wen ^a   Gong, Guohua ^a   Li, Dan ^a   He, Yang ^a   Zhao, Yinlan ^a  

^a Cancer Center   (China)

Author keywords

Acute and sub chronic dosing; Dioscorea zingiberensis C.H.Wright; Metabolite; Oral toxicity; Steroidal saponins

Indexed keywords

ALANINE AMINOTRANSFERASE; ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; BILIRUBIN; BILIRUBIN GLUCURONIDE; DIOSGENIN; GLUTATHIONE; GLUTATHIONE REDUCTASE; GLUTATHIONE TRANSFERASE; SAPONIN DERIVATIVE;

ACUTE TOXICITY; ADULT ANIMAL; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; BILIARY EXCRETION; BILIRUBIN BLOOD LEVEL; CELL VACUOLE; CHOLESTASIS; CHRONIC TOXICITY; CONTROLLED STUDY; CYTOPLASM; DIOSCOREA ZINGIBERENSIS; DIOSCOREACEAE; DOSE RESPONSE; DRUG OVERDOSE; DRUG SAFETY; ETHNOPHARMACOLOGY; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HISTOPATHOLOGY; HYPERBILIRUBINEMIA; IN VIVO STUDY; INTRAHEPATIC BILE DUCT; LIVER; LIVER CELL; LIVER LEVEL; LIVER TOXICITY; MALE; MASS SPECTROMETRY; METABOLITE; MORTALITY; MOUSE; NONHUMAN; RAT; RHIZOME; SINGLE DRUG DOSE; SPRAGUE DAWLEY RAT; TOXICITY TESTING; YAM;

ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DIOSCOREA; ENZYMES; FEMALE; LIVER; MALE; MICE; PLANT EXTRACTS; SAPONINS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; STEROIDS;

DIOSCOREA ZINGIBERENSIS; MUS; RATTUS; RODENTIA;

EID: 70450222919     PISSN: 03788741     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jep.2009.08.047     Document Type: Article

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