메뉴 건너뛰기




Volumn 47, Issue 4, 2009, Pages 279-285

Aconite poisoning

Author keywords

Aconite roots; Aconitine; Aconitum species; Cardiotoxins; Herbal medicines; Neurotoxins; Ventricular arrhythmias

Indexed keywords

ACETYLCHOLINE; ACONITINE; ACONITUM EXTRACT; ALKALOID; AMIODARONE; ANTIARRHYTHMIC AGENT; ATROPINE; CARDIOTOXIN; CHARCOAL; FLECAINIDE; HYPACONITINE; JESACONITINE; MESACONITINE; MEXILETINE; NEUROTOXIN; PROCAINAMIDE; UNCLASSIFIED DRUG; VOLTAGE GATED SODIUM CHANNEL; YUNACONITINE; PLANT TOXIN;

EID: 67649172262     PISSN: 15563650     EISSN: 15569519     Source Type: Journal    
DOI: 10.1080/15563650902904407     Document Type: Review
Times cited : (327)

References (56)
  • 1
    • 0019779164 scopus 로고
    • Arrow poisons in China. Part II. Aconitum - Botany, chemistry, and pharmacology
    • Bisset NG. Arrow poisons in China. Part II. Aconitum - botany, chemistry, and pharmacology. J Ethnopharmacol 1981; 4:247-336.
    • (1981) J Ethnopharmacol , vol.4 , pp. 247-336
    • Bisset, N.G.1
  • 2
    • 41749099932 scopus 로고    scopus 로고
    • Salade malade: Malignant ventricular arrhythmias due to an accidental intoxification with Aconitum napellus
    • Weijters BJ, Verbunt RJAM, Hoogsteen J, Visser RF. Salade malade: malignant ventricular arrhythmias due to an accidental intoxification with Aconitum napellus. Neth Heart J 2008; 16:96-99.
    • (2008) Neth Heart J , vol.16 , pp. 96-99
    • Weijters, B.J.1    Rjam, V.2    Hoogsteen, J.3    Visser, R.F.4
  • 4
    • 0027980234 scopus 로고
    • Aconitine poisoning: A global perspective
    • Chan TYK. Aconitine poisoning: a global perspective. Vet Hum Toxicol 1994; 36:326-328.
    • (1994) Vet Hum Toxicol , vol.36 , pp. 326-328
    • Chan, T.Y.K.1
  • 8
    • 25844481084 scopus 로고    scopus 로고
    • Herbal aconite tea and refractory ventricular tachycardia (letter)
    • Lowe L, Matteucci MJ, Schneir AB. Herbal aconite tea and refractory ventricular tachycardia (letter). N Engl J Med 2005; 353:1532.
    • (2005) N Engl J Med , vol.353 , pp. 1532
    • Lowe, L.1    Matteucci, M.J.2    Schneir, A.B.3
  • 9
    • 0024983495 scopus 로고
    • Aconite in homeopathic relief of post-operative pain and agitation in children [in French]
    • Alibeu JP. Jobert J. Aconite in homeopathic relief of post-operative pain and agitation in children [in French]. Pediatrie 1990; 45:465-466.
    • (1990) Pediatrie , vol.45 , pp. 465-466
    • Alibeu, J.P.1    Jobert, J.2
  • 10
    • 0032711209 scopus 로고    scopus 로고
    • Bradycardia, reversible panconduction defect and syncope following self-medication
    • Guha S, Dawn B, Dutta G, Chakraborty T, Pain S. Bradycardia, reversible panconduction defect and syncope following self-medication. Cardiology 1999; 91:268-271.
    • (1999) Cardiology , vol.91 , pp. 268-271
    • Guha, S.1    Dawn, B.2    Dutta, G.3    Chakraborty, T.4    Pain, S.5
  • 12
    • 0014538586 scopus 로고
    • Cardiovascular aspects of aconite poisoning in human beings
    • Kapoor SC, Sen AK. Cardiovascular aspects of aconite poisoning in human beings. Indian Heart J 1969; 21:329-338.
    • (1969) Indian Heart J , vol.21 , pp. 329-338
    • Kapoor, S.C.1    Sen, A.K.2
  • 14
    • 0023707507 scopus 로고
    • Hypaconitine the dominant constituent responsible for the neuromuscular blocking action of the Japanese-Sino medicine "bushi" (aconite root)
    • Kimura M, Muroi M, Kimura I, Sakai S, Kitagawa I. Hypaconitine, the dominant constituent responsible for the neuromuscular blocking action of the Japanese-Sino medicine "Bushi" (aconite root). Jpn J Pharmacol 1988; 48:290-293.
    • (1988) Jpn J Pharmacol , vol.48 , pp. 290-293
    • Kimura, M.1    Muroi, M.2    Kimura, I.3    Sakai, S.4    Kitagawa, I.5
  • 15
    • 33748549639 scopus 로고    scopus 로고
    • Hidden aconite poisoning: Identification of yunaconitine and related Aconitum alkaloids in urine by liquid chromatography - Tandem mass spectrometry
    • Lai CK, Poon WT, Chan AYW. Hidden aconite poisoning: identification of yunaconitine and related Aconitum alkaloids in urine by liquid chromatography - tandem mass spectrometry. J Anal Toxicol 2006; 30:426-433.
    • (2006) J Anal Toxicol , vol.30 , pp. 426-433
    • Lai, C.K.1    Poon, W.T.2    Chan, A.Y.W.3
  • 16
    • 0030020364 scopus 로고    scopus 로고
    • Determination of Aconitum alkaloids in the tubers of Aconitum japonicum using gas chromatography/selected ion monitoring
    • Ito K, Ohyama Y, Hishinuma T, Mizugaki M. Determination of Aconitum alkaloids in the tubers of Aconitum japonicum using gas chromatography/selected ion monitoring. Planta Med 1996; 62:57-59.
    • (1996) Planta Med , vol.62 , pp. 57-59
    • Ito, K.1    Ohyama, Y.2    Hishinuma, T.3    Mizugaki, M.4
  • 17
    • 34548497641 scopus 로고    scopus 로고
    • Simultaneous determination of three Aconitum alkaloids in urine by LC-MS-MS
    • Wang ZH, Wang ZP, Wen J, He Y. Simultaneous determination of three Aconitum alkaloids in urine by LC-MS-MS. J Pharm Biomed Anal 2007; 45:145-148.
    • (2007) J Pharm Biomed Anal , vol.45 , pp. 145-148
    • Wang, Z.H.1    Wang, Z.P.2    Wen, J.3    He, Y.4
  • 18
    • 0031984883 scopus 로고    scopus 로고
    • Cardiac effects of lappaconitine and N-deacetyllappaconitine, two diterpenoid alkaloids from plants of the Aconitum and Delphinium species
    • Heubach JF, Schute A. Cardiac effects of lappaconitine and N-deacetyllappaconitine, two diterpenoid alkaloids from plants of the Aconitum and Delphinium species. Planta Med 1998; 64:22-26.
    • (1998) Planta Med , vol.64 , pp. 22-26
    • Heubach, J.F.1    Schute, A.2
  • 19
    • 0030697406 scopus 로고    scopus 로고
    • Aconitum sp. alkaloids: The modulation of voltage-dependent Na+ channels, toxicity and antinociceptive properties
    • Friese J, Gleitz J, Gutser UT, Heubach JF, Matthiesen T, Wilffert B, Selve N. Aconitum sp. alkaloids: the modulation of voltage-dependent Na+ channels, toxicity and antinociceptive properties. Eur J Pharmacol 1997; 337:165-174.
    • (1997) Eur J Pharmacol , vol.337 , pp. 165-174
    • Friese, J.1    Gleitz, J.2    Gutser, U.T.3    Heubach, J.F.4    Matthiesen, T.5    Wilffert, B.6    Selve, N.7
  • 20
    • 0028006669 scopus 로고
    • Positive chronotropic and inotropic effects of higenamine and its enhancing action on the aconitine-induced tachyarrhythmia in isolated murine atria
    • Kimura I, Makino M, Takamura Y, Islam MA, Kimura M. Positive chronotropic and inotropic effects of higenamine and its enhancing action on the aconitine-induced tachyarrhythmia in isolated murine atria. Jpn J Pharmacol 1994; 66:75-80.
    • (1994) Jpn J Pharmacol , vol.66 , pp. 75-80
    • Kimura, I.1    Makino, M.2    Takamura, Y.3    Islam, M.A.4    Kimura, M.5
  • 21
    • 2342441642 scopus 로고    scopus 로고
    • Clinical features and management of herb-induced aconitine poisoning
    • Lin CC, Chan TYK, Deng JF. Clinical features and management of herb-induced aconitine poisoning. Ann Emerg Med 2004; 43:574-579.
    • (2004) Ann Emerg Med , vol.43 , pp. 574-579
    • Lin, C.C.1    Chan, T.Y.K.2    Deng, J.F.3
  • 22
    • 0021428542 scopus 로고
    • Quantitative determination of total alkaloids and aconitine in the root of Aconitum carmichaeli and Aconitum kusnezoffii [in Chinese]
    • Sun WJ. Quantitative determination of total alkaloids and aconitine in the root of Aconitum carmichaeli and Aconitum kusnezoffii [in Chinese]. Chung Yao Tung Pao 1984; 9:125-127.
    • (1984) Chung Yao Tung Pao , vol.9 , pp. 125-127
    • Sun, W.J.1
  • 23
    • 0027598221 scopus 로고
    • Determination of aconitine in wutou and related herbal drugs (roots of Aconitum) and their processed products in Hong Kong market [in Chinese]
    • 318
    • Cao H. Determination of aconitine in wutou and related herbal drugs (roots of Aconitum) and their processed products in Hong Kong market [in Chinese]. Chung-Kuo Chung Yao Tsa Chih 1993; 18:279-281, 318.
    • (1993) Chung-Kuo Chung Yao Tsa Chih , vol.18 , pp. 279-281
    • Cao, H.1
  • 25
    • 0028237320 scopus 로고
    • Three fatal cases of herbal aconite poisoning
    • But PPH, Tai YT, Young K. Three fatal cases of herbal aconite poisoning. Vet Hum Toxicol 1994; 38:212-215.
    • (1994) Vet Hum Toxicol , vol.38 , pp. 212-215
    • But, P.P.H.1    Tai, Y.T.2    Young, K.3
  • 26
    • 0029914105 scopus 로고    scopus 로고
    • Effects of antiarrhythmic agents and Mg2+ on aconitine-induced arrhythmias
    • Sawanobori T, Adaniya H, Hirano Y, Hiraoka M. Effects of antiarrhythmic agents and Mg2+ on aconitine-induced arrhythmias. Jpn Heart J 1996; 37:709-718.
    • (1996) Jpn Heart J , vol.37 , pp. 709-718
    • Sawanobori, T.1    Adaniya, H.2    Hirano, Y.3    Hiraoka, M.4
  • 27
    • 0027196554 scopus 로고
    • R56865, a Na+/Ca2+-overload inhibitor, protects against aconitine-induced cardiac arrhythmias in vivo
    • Lu HR, De Clerck F. R56865, a Na+/Ca2+-overload inhibitor, protects against aconitine-induced cardiac arrhythmias in vivo. J Cardiovasc Pharmacol 1993; 22:120-125.
    • (1993) J Cardiovasc Pharmacol , vol.22 , pp. 120-125
    • Lu, H.R.1    De Clerck, F.2
  • 28
    • 3042688163 scopus 로고    scopus 로고
    • Effects of sodium-calcium exchange inhibitors, KB-R7943 and SEA0400, on aconitine-induced arrhythmias in guinea pigs in vivo, in vitro, and in computer simulation studies
    • Amran MS, Hashimoto K, Homma N. Effects of sodium-calcium exchange inhibitors, KB-R7943 and SEA0400, on aconitine-induced arrhythmias in guinea pigs in vivo, in vitro, and in computer simulation studies. J Pharmacol Exp Ther 2004; 310:83-89.
    • (2004) J Pharmacol Exp Ther , vol.310 , pp. 83-89
    • Amran, M.S.1    Hashimoto, K.2    Homma, N.3
  • 30
    • 0020683966 scopus 로고
    • The positive inotropic effect of aconitine
    • Honerjäger P, Meissner A. The positive inotropic effect of aconitine. N-S Arch Pharmacol 1983; 322:49-58.
    • (1983) N-S Arch Pharmacol , vol.322 , pp. 49-58
    • Honerjäger, P.1    Meissner, A.2
  • 31
    • 0036177561 scopus 로고    scopus 로고
    • Aconitine facilitates spontaneous transmitter release at rat ventromedial hypothalamic neurons
    • Yamanaka H, Doi A, Ishibashi H, Akaike N. Aconitine facilitates spontaneous transmitter release at rat ventromedial hypothalamic neurons. Br J Pharmacol 2002; 135:816-822.
    • (2002) Br J Pharmacol , vol.135 , pp. 816-822
    • Yamanaka, H.1    Doi, A.2    Ishibashi, H.3    Akaike, N.4
  • 32
    • 0032557925 scopus 로고    scopus 로고
    • Activity of ventromedial hypothalamic neurons suppressing heart rate is associated with paradoxical sleep in the rat
    • Hirasawa M, Nishihara M, Takahashi M. Activity of ventromedial hypothalamic neurons suppressing heart rate is associated with paradoxical sleep in the rat. Brain Res 1998; 797:103-108.
    • (1998) Brain Res , vol.797 , pp. 103-108
    • Hirasawa, M.1    Nishihara, M.2    Takahashi, M.3
  • 33
    • 0025281528 scopus 로고
    • Blocking effects of hypaconitine and aconitine on nerve action potentials in phrenic nerve-diaphragm muscles of mice
    • Muroi M, Kimura I, Kimura M. Blocking effects of hypaconitine and aconitine on nerve action potentials in phrenic nerve-diaphragm muscles of mice. Neuropharmacology 1990; 29:567-572.
    • (1990) Neuropharmacology , vol.29 , pp. 567-572
    • Muroi, M.1    Kimura, I.2    Kimura, M.3
  • 35
    • 0031857541 scopus 로고    scopus 로고
    • Quantitative analysis of Aconitum alkaloids in the urine and serum of a male attempting suicide by oral intake of aconite extract
    • Mizugaki M, Ito K, Ohyama Y, Konishi Y, Tanaka S, Kurasawa K. Quantitative analysis of Aconitum alkaloids in the urine and serum of a male attempting suicide by oral intake of aconite extract. J Anal Toxicol 1998; 22:336-340.
    • (1998) J Anal Toxicol , vol.22 , pp. 336-340
    • Mizugaki, M.1    Ito, K.2    Ohyama, Y.3    Konishi, Y.4    Tanaka, S.5    Kurasawa, K.6
  • 36
    • 33746102573 scopus 로고    scopus 로고
    • Effect of cytochromes P450 chemical inhibitors and monoclonal antibodies on human microsomal esterase activity
    • Polsky-Fisher SL, Cao H, Lu P, Gibson CR. Effect of cytochromes P450 chemical inhibitors and monoclonal antibodies on human microsomal esterase activity. Drug Metab Dispos 2006; 34:1361-1366.
    • (2006) Drug Metab Dispos , vol.34 , pp. 1361-1366
    • Polsky-Fisher, S.L.1    Cao, H.2    Lu, P.3    Gibson, C.R.4
  • 37
    • 24344504895 scopus 로고    scopus 로고
    • Separation and identification of Aconitum alkaloids and their metabolites in human urine
    • Zhang HG, Sun Y, Duan MY, Chen YJ, Zhong DF, Zhang HQ. Separation and identification of Aconitum alkaloids and their metabolites in human urine. Toxicon 2005; 46:500-506.
    • (2005) Toxicon , vol.46 , pp. 500-506
    • Zhang, H.G.1    Sun, Y.2    Duan, M.Y.3    Chen, Y.J.4    Zhong, D.F.5    Zhang, H.Q.6
  • 39
    • 33751215189 scopus 로고    scopus 로고
    • Characterization of metabolites and cytochrome P450 isoforms involved in the microsomal metabolism of aconitine
    • Wang Y, Wang S, Liu Y, Yan L, Dou G, Gao Y. Characterization of metabolites and cytochrome P450 isoforms involved in the microsomal metabolism of aconitine. J Chromatogr B 2006; 844:292-300.
    • (2006) J Chromatogr B , vol.844 , pp. 292-300
    • Wang, Y.1    Wang, S.2    Liu, Y.3    Yan, L.4    Dou, G.5    Gao, Y.6
  • 40
    • 0033931165 scopus 로고    scopus 로고
    • Distribution of Aconitum alkaloids in body fluids and tissues in a suicidal case of aconite ingestion
    • Ito K, Tanaka S, Funayama M, Mizugaki M. Distribution of Aconitum alkaloids in body fluids and tissues in a suicidal case of aconite ingestion. J Anal Toxicol 2000; 24:348-353.
    • (2000) J Anal Toxicol , vol.24 , pp. 348-353
    • Ito, K.1    Tanaka, S.2    Funayama, M.3    Mizugaki, M.4
  • 41
    • 67649945653 scopus 로고    scopus 로고
    • Two survival cases of severe aconite poisoning by percutaneous cardiopulmonary support system and cardiopulmonary bypass for fatal arrhythmia: A case report
    • Niinuma H, Aoki H, Suzuki T, Shibata M, Moriai Y, Suzuki T, Ohuchi S, Kawazoe K, Hiramori K. Two survival cases of severe aconite poisoning by percutaneous cardiopulmonary support system and cardiopulmonary bypass for fatal arrhythmia: a case report. Internet J Emerg Intens Care Med 2003; 6(2).
    • (2003) Internet J Emerg Intens Care Med , vol.6 , Issue.2
    • Niinuma, H.1    Aoki, H.2    Suzuki, T.3    Shibata, M.4    Moriai, Y.5    Suzuki, T.6    Ohuchi, S.7    Kawazoe, K.8    Hiramori, K.9
  • 45
    • 0026479908 scopus 로고
    • Cardiotoxicity after herb-induced aconite poison
    • Tai YT, But PBH, Young K, Lau CP. Cardiotoxicity after herb-induced aconite poison. Lancet 1992; 340:1254-1256.
    • (1992) Lancet , vol.340 , pp. 1254-1256
    • Tai, Y.T.1    But, P.B.H.2    Young, K.3    Lau, C.P.4
  • 46
    • 0028345157 scopus 로고
    • Herb-induced aconitine poisoning presenting as tetraplegia
    • Chan TYK, Tomlinson B, Critchley JAJH, Cockram CS. Herb-induced aconitine poisoning presenting as tetraplegia. Vet Hum Toxicol 1994; 36:133-134.
    • (1994) Vet Hum Toxicol , vol.36 , pp. 133-134
    • Chan, T.Y.K.1    Tomlinson, B.2    Jajh, C.3    Cockram, C.S.4
  • 49
    • 13244264664 scopus 로고    scopus 로고
    • A multidisciplinary approach to the toxicologic problems associated with the use of herbal medicines
    • Chan TYK, Tam HP, Lai CK, Chan AYW. A multidisciplinary approach to the toxicologic problems associated with the use of herbal medicines. Ther Drug Monit 2005; 27:53-57.
    • (2005) Ther Drug Monit , vol.27 , pp. 53-57
    • Chan, T.Y.K.1    Tam, H.P.2    Lai, C.K.3    Chan, A.Y.W.4
  • 51
    • 2542478454 scopus 로고    scopus 로고
    • Oral class III antiarrhythmics: What is new?
    • Khan MH. Oral class III antiarrhythmics: what is new? Curr Opin Cardiol 2004; 19:47-51.
    • (2004) Curr Opin Cardiol , vol.19 , pp. 47-51
    • Khan, M.H.1
  • 53
    • 0036144594 scopus 로고    scopus 로고
    • Acute aconitine poisoned patients with ventricular arrhythmias successfully reversed by charcoal hemoperfusion (letter)
    • Lin CC, Chou HL, Lin JL. Acute aconitine poisoned patients with ventricular arrhythmias successfully reversed by charcoal hemoperfusion (letter). Am J Emerg Med 2002; 20:66-67.
    • (2002) Am J Emerg Med , vol.20 , pp. 66-67
    • Lin, C.C.1    Chou, H.L.2    Lin, J.L.3
  • 54
    • 0036312402 scopus 로고    scopus 로고
    • Percutaneous cardiopulmonary bypass for cardiac emergencies
    • Kurusz M, Zwischenberger JB. Percutaneous cardiopulmonary bypass for cardiac emergencies. Perfusion 2002; 17:269-277.
    • (2002) Perfusion , vol.17 , pp. 269-277
    • Kurusz, M.1    Zwischenberger, J.B.2
  • 55
    • 0026576728 scopus 로고
    • Aconite: A lethal Chinese herb
    • Fatovich DM. Aconite: a lethal Chinese herb. Ann Emerg Med 1992; 21:309-311.
    • (1992) Ann Emerg Med , vol.21 , pp. 309-311
    • Fatovich, D.M.1
  • 56
    • 0036395232 scopus 로고    scopus 로고
    • Incidence of herb-induced aconitine poisoning in Hong Kong: Impact of publicity measures to promote awareness among the herbalists and the public
    • Chan TYK. Incidence of herb-induced aconitine poisoning in Hong Kong: impact of publicity measures to promote awareness among the herbalists and the public. Drug Saf 2002; 25:823-828.
    • (2002) Drug Saf , vol.25 , pp. 823-828
    • Chan, T.Y.K.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.