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Bioorganic and Medicinal Chemistry

Volumn 21, Issue 7, 2013, Pages 1680-1684

Discovery of dopamine D4 receptor antagonists with planar chirality

(6) Sanna, Fabrizio a Ortner, Birgit a Hübner, Harald a Löber, Stefan a Tschammer, Nuska a Gmeiner, Peter a

a UNIVERSITY OF ERLANGEN NUREMBERG (Germany)

Author keywords

Dopamine; GPCR; Ligand efficacy; Paracyclophane; Planar chirality; Subtype selectivity

Indexed keywords

1 (1 PARACYCLOPHANE 4 YL 1H PYRAZOLE 4 YLMETHYL) 4 PHENYL PIPERAZINE; 1 (1 PHENYL 1H PYRAZOL 4 YLMETHYL) 4 [2.2]PARACYCLOPHAN 4 YL PIPERAZINE; 1 PHENYLPIPERAZINE DERIVATIVE; DOPAMINE 2 RECEPTOR; DOPAMINE 3 RECEPTOR; DOPAMINE 4 RECEPTOR; DOPAMINE RECEPTOR; PARACYCLOPHANE 4 YL 1H PYRAZOLE; PARACYCLOPHANE 4 YL 1H PYRAZOLE 4 CARBALDEHYDE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; BIOLUMINESCENCE; CHIRALITY; DRUG EFFICACY; DRUG STRUCTURE; DRUG SYNTHESIS; ENANTIOMER; METALLATION; RECEPTOR BINDING; SYNTHESIS; THIN LAYER CHROMATOGRAPHY;

ANIMALS; CHO CELLS; CRICETINAE; DOPAMINE ANTAGONISTS; HUMANS; PIPERAZINES; RECEPTORS, DOPAMINE D4; STEREOISOMERISM;

EID: 84875212940 PISSN: 09680896 EISSN: 14643391 Source Type: Journal
DOI: 10.1016/j.bmc.2013.01.065 Document Type: Article

Times cited : (7)

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