Pioglitazone Improves Cognitive Function via Increasing Insulin Sensitivity and Strengthening Antioxidant Defense System in Fructose-Drinking Insulin Resistance Rats

PLoS ONE

Volumn 8, Issue 3, 2013, Pages

  Yin, Qing Qing ^a   Pei, Jin Jing ^b   Xu, Song ^a   Luo, Ding Zhen ^a   Dong, Si Qing ^a   Sun, Meng Han ^a   You, Li ^a   Sun, Zhi Jian ^a   Liu, Xue Ping ^a  

^a SHANDONG PROVINCIAL HOSPITAL AFFILIATED TO SHANDONG UNIVERSITY   (China)

^b KAROLINSKA INSTITUTE   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCHOLINE; ACETYLCHOLINESTERASE; CATALASE; FRUCTOSE; GLUCOSE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; INSULIN; PIOGLITAZONE; REACTIVE OXYGEN METABOLITE; SUPEROXIDE DISMUTASE; THIOBARBITURIC ACID REACTIVE SUBSTANCE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT DEFENSE SYSTEM; ARTICLE; BRAIN CORTEX; BRAIN DAMAGE; BRAIN TISSUE; CHOLINERGIC SYSTEM; COGNITIVE DEFECT; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFICACY; GLUCOSE BLOOD LEVEL; HIPPOCAMPUS; HISTOPATHOLOGY; INSULIN BLOOD LEVEL; INSULIN RESISTANCE; INSULIN SENSITIVITY; LEARNING DISORDER; LIPID PEROXIDATION; MALE; MAZE TEST; MEMORY DISORDER; METABOLISM; NONHUMAN; OXIDATIVE STRESS; RAT; TREATMENT DURATION;

ANALYSIS OF VARIANCE; ANIMALS; BRAIN DISEASES; FRUCTOSE; HYPERINSULINISM; INSULIN; INSULIN RESISTANCE; MALE; MAZE LEARNING; MEMORY; PPAR GAMMA; RATS; RATS, WISTAR; REACTIVE OXYGEN SPECIES; THIAZOLIDINEDIONES; THIOBARBITURIC ACID REACTIVE SUBSTANCES;

EID: 84875135190     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0059313     Document Type: Article

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