-
1
-
-
84859404868
-
Role of obesity and lipotoxicity in the development of nonalcoholic steatohepatitis: Pathophysiology and clinical implications
-
Cusi K. Role of obesity and lipotoxicity in the development of nonalcoholic steatohepatitis: pathophysiology and clinical implications. Gastroenterology 2012;142:711-725.
-
(2012)
Gastroenterology
, vol.142
, pp. 711-725
-
-
Cusi, K.1
-
2
-
-
70349764468
-
Role of insulin resistance and lipotoxicity in non-Alcoholic steatohepatitis
-
Cusi K. Role of insulin resistance and lipotoxicity in non-Alcoholic steatohepatitis. Clin Liver Dis 2009;13:545-563.
-
(2009)
Clin Liver Dis
, vol.13
, pp. 545-563
-
-
Cusi, K.1
-
3
-
-
84863098121
-
Inflammation and fibrogenesis in steatohepatitis
-
Fujii H, Kawada N. Inflammation and fibrogenesis in steatohepatitis. J Gastroenterol 2012;47:215-225.
-
(2012)
J Gastroenterol
, vol.47
, pp. 215-225
-
-
Fujii, H.1
Kawada, N.2
-
4
-
-
79951517874
-
From chronic overfeeding to hepatic injury: Role of endoplasmic reticulum stress and inflammation
-
Mollica MP, Lionetti L, Putti R, Cavaliere G, Gaita M, Barletta A. From chronic overfeeding to hepatic injury: role of endoplasmic reticulum stress and inflammation. Nutr Metab Cardiovasc Dis 2011;21:222-230.
-
(2011)
Nutr Metab Cardiovasc Dis
, vol.21
, pp. 222-230
-
-
Mollica, M.P.1
Lionetti, L.2
Putti, R.3
Cavaliere, G.4
Gaita, M.5
Barletta, A.6
-
5
-
-
17244368548
-
Insulin resistance in NASH
-
Choudhury J, Sanyal AJ. Insulin resistance in NASH. Front Biosci 2005;10:1520-1533.
-
(2005)
Front Biosci
, vol.10
, pp. 1520-1533
-
-
Choudhury, J.1
Sanyal, A.J.2
-
6
-
-
0036783050
-
The metabolic abnormalities associated with non-Alcoholic fatty liver disease
-
Haque M, Sanyal AJ. The metabolic abnormalities associated with non-Alcoholic fatty liver disease. Best Pract Res Clin Gastroenterol 2002;16:709-731.
-
(2002)
Best Pract Res Clin Gastroenterol
, vol.16
, pp. 709-731
-
-
Haque, M.1
Sanyal, A.J.2
-
7
-
-
33745418743
-
Insulin resistance in non-Alcoholic fatty liver disease
-
Park JH. Insulin resistance in non-Alcoholic fatty liver disease. Korean J Hepatol 2006;12:16-30.
-
(2006)
Korean J Hepatol
, vol.12
, pp. 16-30
-
-
Park, J.H.1
-
8
-
-
30944455145
-
Insulin resistance: A metabolic pathway to chronic liver disease
-
Bugianesi E, McCullough AJ, Marchesini G. Insulin resistance: a metabolic pathway to chronic liver disease. Hepatology 2005;42:987-1000.
-
(2005)
Hepatology
, vol.42
, pp. 987-1000
-
-
Bugianesi, E.1
McCullough, A.J.2
Marchesini, G.3
-
9
-
-
61349140201
-
Nonalcoholic fatty liver disease: The pathogenetic roles of insulin resistance and adipocytokines
-
Polyzos SA, Kountouras J, Zavos C. Nonalcoholic fatty liver disease: the pathogenetic roles of insulin resistance and adipocytokines. Curr Mol Med 2009;9:299-314.
-
(2009)
Curr Mol Med
, vol.9
, pp. 299-314
-
-
Polyzos, S.A.1
Kountouras, J.2
Zavos, C.3
-
10
-
-
34250356015
-
Inhibiting triglyceride synthesis improves hepatic steatosis but exacerbates liver damage and fibrosis in obese mice with nonalcoholic steatohepatitis
-
Yamaguchi K, Yang L, McCall S, et al. Inhibiting triglyceride synthesis improves hepatic steatosis but exacerbates liver damage and fibrosis in obese mice with nonalcoholic steatohepatitis. Hepatology 2007;45:1366-1374.
-
(2007)
Hepatology
, vol.45
, pp. 1366-1374
-
-
Yamaguchi, K.1
Yang, L.2
McCall, S.3
-
11
-
-
77953893410
-
Dissociation between intrahepatic triglyceride content and insulin resistance in familial hypobetalipoproteinemia
-
Amaro A, Fabbrini E, Kars M, et al. Dissociation between intrahepatic triglyceride content and insulin resistance in familial hypobetalipoproteinemia. Gastroenterology 2010;139:149-153.
-
(2010)
Gastroenterology
, vol.139
, pp. 149-153
-
-
Amaro, A.1
Fabbrini, E.2
Kars, M.3
-
12
-
-
65549136260
-
Hepatic lipid partitioning and liver damage in nonalcoholic fatty liver disease: Role of stearoyl-CoA desaturase
-
Li ZZ, Berk M, McIntyre TM, Feldstein AE. Hepatic lipid partitioning and liver damage in nonalcoholic fatty liver disease: role of stearoyl-CoA desaturase. J Biol Chem 2009;284:5637-5644.
-
(2009)
J Biol Chem
, vol.284
, pp. 5637-5644
-
-
Li, Z.Z.1
Berk, M.2
McIntyre, T.M.3
Feldstein, A.E.4
-
13
-
-
79960693454
-
Plasma-based approach to measure target engagement for liver-targeting stearoyl-CoA desaturase 1 inhibitors
-
Landry F, Chan CC, Huang Z, et al. Plasma-based approach to measure target engagement for liver-targeting stearoyl-CoA desaturase 1 inhibitors. J Lipid Res 2011;52:1494-1499.
-
(2011)
J Lipid Res
, vol.52
, pp. 1494-1499
-
-
Landry, F.1
Chan, C.C.2
Huang, Z.3
-
14
-
-
80052430139
-
Cloning and expression of stearoyl-CoA desaturase 1 (SCD-1) in the liver of the Sichuan white goose and landes goose responding to overfeeding
-
Pan ZX, Han CC, Wang JW, et al. Cloning and expression of stearoyl-CoA desaturase 1 (SCD-1) in the liver of the Sichuan white goose and landes goose responding to overfeeding. Mol Biol Rep 2011;38:3417-3425.
-
(2011)
Mol Biol Rep
, vol.38
, pp. 3417-3425
-
-
Pan, Z.X.1
Han, C.C.2
Wang, J.W.3
-
15
-
-
33747626511
-
Mitochondrial free cholesterol loading sensitizes to TNF- and Fas-mediated steatohepatitis
-
Mari M, Caballero F, Colell A, et al. Mitochondrial free cholesterol loading sensitizes to TNF- and Fas-mediated steatohepatitis. Cell Metab 2006;4:185-198.
-
(2006)
Cell Metab
, vol.4
, pp. 185-198
-
-
Mari, M.1
Caballero, F.2
Colell, A.3
-
16
-
-
0030768236
-
The pharmacology of the antioxidant lipoic acid
-
Biewenga GP, Haenen GR, Bast A. The pharmacology of the antioxidant lipoic acid. Gen Pharmacol 1997;29:315-331.
-
(1997)
Gen Pharmacol
, vol.29
, pp. 315-331
-
-
Biewenga, G.P.1
Haenen, G.R.2
Bast, A.3
-
18
-
-
0026846825
-
Determination of lipoic acid in meat of commercial quality
-
Mattulat A, Baltes W. Determination of lipoic acid in meat of commercial quality. Z Lebensm Unters Forsch 1992;194:326-329.
-
(1992)
Z Lebensm Unters Forsch
, vol.194
, pp. 326-329
-
-
Mattulat, A.1
Baltes, W.2
-
19
-
-
0031409636
-
Analysis of lipoic acid by gas chromatography with flame photometric detection
-
Kataoka H, Hirabayashi N, Makita M. Analysis of lipoic acid by gas chromatography with flame photometric detection. Methods Enzymol 1997;279:166-176.
-
(1997)
Methods Enzymol
, vol.279
, pp. 166-176
-
-
Kataoka, H.1
Hirabayashi, N.2
Makita, M.3
-
20
-
-
47249106357
-
Lipoic acid: A novel therapeutic approach for multiple sclerosis and other chronic inflammatory diseases of the CNS
-
Salinthone S, Yadav V, Bourdette DN, Carr DW. Lipoic acid: a novel therapeutic approach for multiple sclerosis and other chronic inflammatory diseases of the CNS. Endocr Metab Immune Disord Drug Targets 2008;8:132-142.
-
(2008)
Endocr Metab Immune Disord Drug Targets
, vol.8
, pp. 132-142
-
-
Salinthone, S.1
Yadav, V.2
Bourdette, D.N.3
Carr, D.W.4
-
21
-
-
33845726964
-
Increased ROS generation and p53 activation in alpha-lipoic acid-induced apoptosis of hepatoma cells
-
Simbula G, Columbano A, Ledda-Columbano GM, et al. Increased ROS generation and p53 activation in alpha-lipoic acid-induced apoptosis of hepatoma cells. Apoptosis 2007;12:113-123.
-
(2007)
Apoptosis
, vol.12
, pp. 113-123
-
-
Simbula, G.1
Columbano, A.2
Ledda-Columbano, G.M.3
-
22
-
-
84858324850
-
Alpha lipoic acid for symptomatic peripheral neuropathy in patients with diabetes: A meta-Analysis of randomized controlled trials
-
Mijnhout GS, Kollen BJ, Alkhalaf A, Kleefstra N, Bilo HJ. Alpha lipoic acid for symptomatic peripheral neuropathy in patients with diabetes: a meta-Analysis of randomized controlled trials. Int J Endocrinol 2012;2012:456279.
-
(2012)
Int J Endocrinol
, vol.2012
, pp. 456279
-
-
Mijnhout, G.S.1
Kollen, B.J.2
Alkhalaf, A.3
Kleefstra, N.4
Bilo, H.J.5
-
23
-
-
84856065932
-
Maltezos E. Alpha-Lipoic acid, diabetic neuropathy, and Nathan's prophecy
-
Papanas N, Maltezos E. alpha-Lipoic acid, diabetic neuropathy, and Nathan's prophecy. Angiology 2012;63:81-83.
-
(2012)
Angiology
, vol.63
, pp. 81-83
-
-
Papanas, N.1
-
24
-
-
84860323365
-
Critical appraisal of the use of alpha lipoic acid (thioctic acid) in the treatment of symptomatic diabetic polyneuropathy
-
McIlduff CE, Rutkove SB. Critical appraisal of the use of alpha lipoic acid (thioctic acid) in the treatment of symptomatic diabetic polyneuropathy. Ther Clin Risk Manag 2011;7:377-385.
-
(2011)
Ther Clin Risk Manag
, vol.7
, pp. 377-385
-
-
McIlduff, C.E.1
Rutkove, S.B.2
-
25
-
-
84871432569
-
Efficacy and safety of high-dose alpha-lipoic acid in the treatment of diabetic polyneuropathy
-
Gu XM, Zhang SS, Wu JC, et al. Efficacy and safety of high-dose alpha-lipoic acid in the treatment of diabetic polyneuropathy. Zhonghua Yi Xue Za Zhi 2010;90:2473-2476.
-
(2010)
Zhonghua Yi Xue Za Zhi
, vol.90
, pp. 2473-2476
-
-
Gu, X.M.1
Zhang, S.S.2
Wu, J.C.3
-
26
-
-
77951943315
-
Alpha lipoic acid a new treatment for neuropathic pain in patients with diabetes?
-
Mijnhout GS, Alkhalaf A, Kleefstra N, Bilo HJ. Alpha lipoic acid: a new treatment for neuropathic pain in patients with diabetes? Neth J Med 2010;68:158-162.
-
(2010)
Neth J Med
, vol.68
, pp. 158-162
-
-
Mijnhout, G.S.1
Alkhalaf, A.2
Kleefstra, N.3
Bilo, H.J.4
-
27
-
-
79952987715
-
Sun H. alpha-lipoic acid can improve endothelial dysfunction in subjects with impaired fasting glucose
-
Xiang G, Pu J, Yue L, Hou J, Sun H. alpha-lipoic acid can improve endothelial dysfunction in subjects with impaired fasting glucose. Metabolism 2011;60:480-485.
-
(2011)
Metabolism
, vol.60
, pp. 480-485
-
-
Xiang, G.1
Pu, J.2
Yue, L.3
Hou, J.4
-
28
-
-
75149165328
-
Alpha-lipoic acid improves vascular endothelial function in patients with type 2 diabetes: A placebo-controlled randomized trial
-
Heinisch BB, Francesconi M, Mittermayer F, et al. Alpha-lipoic acid improves vascular endothelial function in patients with type 2 diabetes: a placebo-controlled randomized trial. Eur J Clin Invest 2010;40:148-154.
-
(2010)
Eur J Clin Invest
, vol.40
, pp. 148-154
-
-
Heinisch, B.B.1
Francesconi, M.2
Mittermayer, F.3
-
29
-
-
42149158811
-
Lipoic acid supplementation and endothelial function
-
Tardif JC, Rhéaume E. Lipoic acid supplementation and endothelial function. Br J Pharmacol 2008;153:1587-1588.
-
(2008)
Br J Pharmacol
, vol.153
, pp. 1587-1588
-
-
Tardif, J.C.1
Rhéaume, E.2
-
30
-
-
84856093034
-
Alpha-lipoic acid attenuates methionine choline deficient diet-induced steatohepatitis in C57BL/6 mice
-
Min AK, Kim MK, Kim HS, et al. Alpha-lipoic acid attenuates methionine choline deficient diet-induced steatohepatitis in C57BL/6 mice. Life Sci 2012;90:200-205.
-
(2012)
Life Sci
, vol.90
, pp. 200-205
-
-
Min, A.K.1
Kim, M.K.2
Kim, H.S.3
-
32
-
-
80052543705
-
Prevention of free fatty acid-induced hepatic lipotoxicity by carnitine via reversal of mitochondrial dysfunction
-
Jun DW, Cho WK, Jun JH, et al. Prevention of free fatty acid-induced hepatic lipotoxicity by carnitine via reversal of mitochondrial dysfunction. Liver Int 2011;31:1315-1324.
-
(2011)
Liver Int
, vol.31
, pp. 1315-1324
-
-
Jun, D.W.1
Cho, W.K.2
Jun, J.H.3
-
33
-
-
77955495426
-
Effects of carnitine on peripheral blood mitochondrial DNA copy number and liver function in non-Alcoholic fatty liver disease
-
Lim CY, Jun DW, Jang SS, Cho WK, Chae JD, Jun JH. Effects of carnitine on peripheral blood mitochondrial DNA copy number and liver function in non-Alcoholic fatty liver disease. Korean J Gastroenterol 2010;55:384-389.
-
(2010)
Korean J Gastroenterol
, vol.55
, pp. 384-389
-
-
Lim, C.Y.1
Jun, D.W.2
Jang, S.S.3
Cho, W.K.4
Chae, J.D.5
Jun, J.H.6
-
34
-
-
51449084024
-
Lipoic acid as an anti-inflammatory and neuroprotective treatment for Alzheimer's disease
-
Maczurek A, Hager K, Kenklies M, et al. Lipoic acid as an anti-inflammatory and neuroprotective treatment for Alzheimer's disease. Adv Drug Deliv Rev 2008;60:1463-1470.
-
(2008)
Adv Drug Deliv Rev
, vol.60
, pp. 1463-1470
-
-
MacZurek, A.1
Hager, K.2
Kenklies, M.3
-
35
-
-
84866732263
-
Lipoic acid improves mitochondrial function in nonalcoholic steatosis through the stimulation of sirtuin 1 and sirtuin 3
-
Valdecantos MP, Pérez-Matute P, González-Muniesa P, Prieto-Hontoria PL, Moreno-Aliaga MJ, Martínez JA. Lipoic acid improves mitochondrial function in nonalcoholic steatosis through the stimulation of sirtuin 1 and sirtuin 3. Obesity (Silver Spring) 2012;20:1974-1983.
-
(2012)
Obesity (Silver Spring)
, vol.20
, pp. 1974-1983
-
-
Valdecantos, M.P.1
Pérez-Matute, P.2
González-Muniesa, P.3
Prieto-Hontoria, P.L.4
Moreno-Aliaga, M.J.5
Martínez, J.A.6
-
36
-
-
1642471491
-
Effects of intraperitoneally administered lipoic acid, vitamin E, and linalool on the level of total lipid and fatty acids in guinea pig brain with oxidative stress induced by H2O2
-
Celik S, Ozkaya A. Effects of intraperitoneally administered lipoic acid, vitamin E, and linalool on the level of total lipid and fatty acids in guinea pig brain with oxidative stress induced by H2O2. J Biochem Mol Biol 2002;35:547-552.
-
(2002)
J Biochem Mol Biol
, vol.35
, pp. 547-552
-
-
Celik, S.1
Ozkaya, A.2
-
37
-
-
0036942182
-
Effects of alpha lipoic acid, ascorbic acid-6-palmitate, and fish oil on the glutathione, malonaldehyde, and fatty acids levels in erythrocytes of streptozotocin induced diabetic male rats
-
Yilmaz O, Ozkan Y, Yildirim M, Oztürk AI, Er?an Y. Effects of alpha lipoic acid, ascorbic acid-6-palmitate, and fish oil on the glutathione, malonaldehyde, and fatty acids levels in erythrocytes of streptozotocin induced diabetic male rats. J Cell Biochem 2002;86:530-539.
-
(2002)
J Cell Biochem
, vol.86
, pp. 530-539
-
-
Yilmaz, O.1
Ozkan, Y.2
Yildirim, M.3
Oztürk, A.I.4
Eran, Y.5
-
38
-
-
66249083144
-
Mitochondrial cholesterol loading exacerbates amyloid beta peptide-induced inflammation and neurotoxicity
-
Fernández A, Llacuna L, Fernández-Checa JC, Colell A. Mitochondrial cholesterol loading exacerbates amyloid beta peptide-induced inflammation and neurotoxicity. J Neurosci 2009;29:6394-6405.
-
(2009)
J Neurosci
, vol.29
, pp. 6394-6405
-
-
Fernández, A.1
Llacuna, L.2
Fernández-Checa, J.C.3
Colell, A.4
|