High-Intensity Endurance Training Results in Faster Vessel-Specific Rate of Vasorelaxation in Type 1 Diabetic Rats

PLoS ONE

Volumn 8, Issue 3, 2013, Pages

  Murias, Juan M ^a   Dey, Adwitia ^a   Campos, Oscar A ^a   Estaki, Mehrbod ^a   Hall, Katharine E ^a   Melling, Christopher W J ^a   Noble, Earl G ^a  

^a UNIVERSITY OF WESTERN ONTARIO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ENDOTHELIAL NITRIC OXIDE SYNTHASE; GLUCOSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD VESSEL REACTIVITY; CONTROLLED STUDY; ENDURANCE TRAINING; EXERCISE INTENSITY; FEMORAL ARTERY; GLUCOSE BLOOD LEVEL; ILIAC ARTERY; INSULIN DEPENDENT DIABETES MELLITUS; MALE; NONHUMAN; PROTEIN CONTENT; RAT; RESISTANCE TRAINING; STEADY STATE; VASODILATATION; WESTERN BLOTTING;

ANALYSIS OF VARIANCE; ANIMALS; AORTA; BLOTTING, WESTERN; DIABETES MELLITUS, EXPERIMENTAL; FEMORAL ARTERY; HISTOLOGICAL TECHNIQUES; ILIAC ARTERY; MALE; MODELS, BIOLOGICAL; PHYSICAL CONDITIONING, ANIMAL; PHYSICAL ENDURANCE; RATS; RATS, SPRAGUE-DAWLEY; VASODILATION;

EID: 84875119672     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0059678     Document Type: Article

References (52)

1. Avogaro A, Albiero M, Menegazzo L, de Kreutzenberg S, Fadini GP, (2011) Endothelial dysfunction in diabetes: the role of reparatory mechanisms. Diabetes Care 34Suppl 2: S285-290.
2. Ding H, Triggle CR, (2010) Endothelial dysfunction in diabetes: multiple targets for treatment. Pflugers Arch 459: 977-994.
3. Hadi HA, Suwaidi JA, (2007) Endothelial dysfunction in diabetes mellitus. Vasc Health Risk Manag 3: 853-876.
4. Johnstone MT, Creager SJ, Scales KM, Cusco JA, Lee BK, et al. (1993) Impaired endothelium-dependent vasodilation in patients with insulin-dependent diabetes mellitus. Circulation 88: 2510-2516.
5. Merimee TJ, (1990) Diabetic retinopathy. A synthesis of perspectives. N Engl J Med 322: 978-983.
6. Reusch JE, Wang CC, (2011) Cardiovascular disease in diabetes: where does glucose fit in? J Clin Endocrinol Metab 96: 2367-2376.
7. Furchgott RF, Zawadzki JV, (1980) The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine. Nature 288: 373-376.
8. Stamler JS, Loh E, Roddy MA, Currie KE, Creager MA, (1994) Nitric oxide regulates basal systemic and pulmonary vascular resistance in healthy humans. Circulation 89: 2035-2040.
9. Behnke BJ, Delp MD, (2010) Aging blunts the dynamics of vasodilation in isolated skeletal muscle resistance vessels. J Appl Physiol 108: 14-20.
10. Murias JM, Campos OA, Hall KE, McDonald MW, Melling CJ, et al. (2013) Vessel-specific rate of vasorelaxation is slower in diabetic rats. Diab Vasc Dis Res 10: 179-186.
11. Melling CWJ, Grise KN, Hasilo CP, Frier BC, Milne KJ, et al. (2013) A model of poorly controlled type 1 diabetes mellitus and its treatment with aerobic exercise training. Diabetes Metab.
12. Fuchsjager-Mayrl G, Pleiner J, Wiesinger GF, Sieder AE, Quittan M, et al. (2002) Exercise training improves vascular endothelial function in patients with type 1 diabetes. Diabetes Care 25: 1795-1801.
13. Goto C, Higashi Y, Kimura M, Noma K, Hara K, et al. (2003) Effect of different intensities of exercise on endothelium-dependent vasodilation in humans: role of endothelium-dependent nitric oxide and oxidative stress. Circulation 108: 530-535.
14. Green DJ, Maiorana A, O'Driscoll G, Taylor R, (2004) Effect of exercise training on endothelium-derived nitric oxide function in humans. J Physiol 561: 1-25.
15. Maiorana A, O'Driscoll G, Cheetham C, Dembo L, Stanton K, et al. (2001) The effect of combined aerobic and resistance exercise training on vascular function in type 2 diabetes. J Am Coll Cardiol 38: 860-866.
16. da Silva CA, Ribeiro JP, Canto JC, da Silva RE, Silva Junior GB, et al. (2012) High-intensity aerobic training improves endothelium-dependent vasodilation in patients with metabolic syndrome and type 2 diabetes mellitus. Diabetes Res Clin Pract 95: 237-245.
17. Sallam N, Khazaei M, Laher I, (2010) Effect of moderate-intensity exercise on plasma C-reactive protein and aortic endothelial function in type 2 diabetic mice. Mediators Inflamm 2010: 149678.
18. Kesaniemi YK, Danforth E Jr, Jensen MD, Kopelman PG, Lefebvre P, et al. (2001) Dose-response issues concerning physical activity and health: an evidence-based symposium. Med Sci Sports Exerc 33: S351-358.
19. Liao F, Li M, Han D, Cao J, Chen K, (2006) Biomechanopharmacology: a new borderline discipline. Trends Pharmacol Sci 27: 287-289.
20. Harrison DG, Widder J, Grumbach I, Chen W, Weber M, et al. (2006) Endothelial mechanotransduction, nitric oxide and vascular inflammation. J Intern Med 259: 351-363.
21. Kadi F, Eriksson A, Holmner S, Butler-Browne GS, Thornell LE, (1999) Cellular adaptation of the trapezius muscle in strength-trained athletes. Histochem Cell Biol 111: 189-195.
22. Maiorana A, O'Driscoll G, Dembo L, Goodman C, Taylor R, et al. (2001) Exercise training, vascular function, and functional capacity in middle-aged subjects. Med Sci Sports Exerc 33: 2022-2028.
23. Rakobowchuk M, McGowan CL, de Groot PC, Hartman JW, Phillips SM, et al. (2005) Endothelial function of young healthy males following whole body resistance training. J Appl Physiol 98: 2185-2190.
24. Rakobowchuk M, McGowan CL, de Groot PC, Bruinsma D, Hartman JW, et al. (2005) Effect of whole body resistance training on arterial compliance in young men. Exp Physiol 90: 645-651.
25. Poelkens F, Rakobowchuk M, Burgomaster KA, Hopman MT, Phillips SM, et al. (2007) Effect of unilateral resistance training on arterial compliance in elderly men. Appl Physiol Nutr Metab 32: 670-676.
26. Rodrigues GJ, Lunardi CN, Lima RG, Santos CX, Laurindo FR, et al. (2008) Vitamin C improves the effect of a new nitric oxide donor on the vascular smooth muscle from renal hypertensive rats. Nitric Oxide 18: 176-183.
27. Ulker S, McKeown PP, Bayraktutan U, (2003) Vitamins reverse endothelial dysfunction through regulation of eNOS and NAD(P)H oxidase activities. Hypertension 41: 534-539.
28. Haram PM, Adams V, Kemi OJ, Brubakk AO, Hambrecht R, et al. (2006) Time-course of endothelial adaptation following acute and regular exercise. Eur J Cardiovasc Prev Rehabil 13: 585-591.
29. Kim E, Sohn S, Lee M, Jung J, Kineman RD, et al. (2006) Differential responses of the growth hormone axis in two rat models of streptozotocin-induced insulinopenic diabetes. J Endocrinol 188: 263-270.
30. Ianuzzo CD, Noble EG, Hamilton N, Dabrowski B, (1982) Effects of streptozotocin diabetes, insulin treatment, and training on the diaphragm. J Appl Physiol 52: 1471-1475.
31. Bedford TG, Tipton CM, Wilson NC, Oppliger RA, Gisolfi CV, (1979) Maximum oxygen consumption of rats and its changes with various experimental procedures. J Appl Physiol 47: 1278-1283.
32. Hornberger TA Jr, Farrar RP, (2004) Physiological hypertrophy of the FHL muscle following 8 weeks of progressive resistance exercise in the rat. Can J Appl Physiol 29: 16-31.
33. Hattori Y, Kawasaki H, Abe K, Kanno M, (1991) Superoxide dismutase recovers altered endothelium-dependent relaxation in diabetic rat aorta. Am J Physiol 261: H1086-1094.
34. Abraham P, Saumet JL, Chevalier JM, (1997) External iliac artery endofibrosis in athletes. Sports Med 24: 221-226.
35. Bergholm R, Makimattila S, Valkonen M, Liu ML, Lahdenpera S, et al. (1999) Intense physical training decreases circulating antioxidants and endothelium-dependent vasodilatation in vivo. Atherosclerosis 145: 341-349.
36. Boule NG, Kenny GP, Haddad E, Wells GA, Sigal RJ, (2003) Meta-analysis of the effect of structured exercise training on cardiorespiratory fitness in Type 2 diabetes mellitus. Diabetologia 46: 1071-1081.
37. Gass G, Gass E, Wicks J, Browning J, Bennett G, et al. (2004) Rate and amplitude of adaptation to two intensities of exercise in men aged 65-75 yr. Med Sci Sports Exerc 36: 1811-1818.
38. Gibala MJ, Little JP, Macdonald MJ, Hawley JA, (2012) Physiological adaptations to low-volume, high-intensity interval training in health and disease. J Physiol 590: 1077-1084.
39. Murias JM, Grise KN, Jiang M, Kowalchuk H, Melling CW, et al. (2013) Acute endurance exercise induces changes in vasorelaxation responses that are vessel-specific. Am J Physiol Regul Integr Comp Physiol.
40. Laughlin MH, Roseguini B, (2008) Mechanisms for exercise training-induced increases in skeletal muscle blood flow capacity: differences with interval sprint training versus aerobic endurance training. J Physiol Pharmacol 59Suppl 7: 71-88.
41. Roseguini BT, Davis MJ, Harold Laughlin M, (2010) Rapid vasodilation in isolated skeletal muscle arterioles: impact of branch order. Microcirculation 17: 83-93.
42. Wagenseil JE, Mecham RP, (2009) Vascular extracellular matrix and arterial mechanics. Physiol Rev 89: 957-989.
43. Johnson LR, Rush JW, Turk JR, Price EM, Laughlin MH, (2001) Short-term exercise training increases ACh-induced relaxation and eNOS protein in porcine pulmonary arteries. J Appl Physiol 90: 1102-1110.
44. Muller-Delp JM, Spier SA, Ramsey MW, Delp MD, (2002) Aging impairs endothelium-dependent vasodilation in rat skeletal muscle arterioles. Am J Physiol Heart Circ Physiol 283: H1662-1672.
45. Fisslthaler B, Dimmeler S, Hermann C, Busse R, Fleming I, (2000) Phosphorylation and activation of the endothelial nitric oxide synthase by fluid shear stress. Acta Physiol Scand 168: 81-88.
46. Matsumoto A, Hirata Y, Momomura S, Fujita H, Yao A, et al. (1994) Increased nitric oxide production during exercise. Lancet 343: 849-850.
47. Beckman JA, Goldfine AB, Gordon MB, Garrett LA, Keaney JF Jr, et al. (2003) Oral antioxidant therapy improves endothelial function in Type 1 but not Type 2 diabetes mellitus. Am J Physiol Heart Circ Physiol 285: H2392-2398.
48. Timimi FK, Ting HH, Haley EA, Roddy MA, Ganz P, et al. (1998) Vitamin C improves endothelium-dependent vasodilation in patients with insulin-dependent diabetes mellitus. J Am Coll Cardiol 31: 552-557.
49. Ting HH, Timimi FK, Boles KS, Creager SJ, Ganz P, et al. (1996) Vitamin C improves endothelium-dependent vasodilation in patients with non-insulin-dependent diabetes mellitus. J Clin Invest 97: 22-28.
50. Mahajan H, Richards SM, Rattigan S, Clark MG, (2004) Local methacholine but not bradykinin potentiates insulin-mediated glucose uptake in muscle in vivo by augmenting capillary recruitment. Diabetologia 47: 2226-2234.
51. Thijssen DH, Willems L, van den Munckhof I, Scholten R, Hopman MT, et al. (2011) Impact of wall thickness on conduit artery function in humans: is there a "Folkow" effect? Atherosclerosis 217: 415-419.
52. McAllister RM, Newcomer SC, Laughlin MH, (2008) Vascular nitric oxide: effects of exercise training in animals. Appl Physiol Nutr Metab 33: 173-178.