RNA-Dependent Protein Kinase Is Essential for 2-Methoxyestradiol-Induced Autophagy in Osteosarcoma Cells

PLoS ONE

Volumn 8, Issue 3, 2013, Pages

  Yang, Caihong ^a,b   Shogren, Kristen L ^a   Goyal, Ribu ^a   Bravo, Dalibel ^a   Yaszemski, Michael J ^a   Maran, Avudaiappan ^a  

^a MAYO CLINIC   (United States)

^b HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

2 METHOXYESTRADIOL; CELL PROTEIN; MICROTUBULE ASSOCIATED PROTEIN; MICROTUBULE ASSOCIATED PROTEIN LC3 I; MICROTUBULE ASSOCIATED PROTEIN LC3 II; PROTEIN ATG7; PROTEIN KINASE; RNA DEPENDENT PROTEIN KINASE; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; CANCER MORPHOLOGY; CONCENTRATION RESPONSE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DOWN REGULATION; DRUG MECHANISM; ENZYME ACTIVITY; HUMAN; HUMAN CELL; IN VITRO STUDY; MUTANT; OSTEOSARCOMA CELL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; TRANSMISSION ELECTRON MICROSCOPY; WESTERN BLOTTING;

ANALYSIS OF VARIANCE; AUTOPHAGY; BLOTTING, WESTERN; CELL LINE, TUMOR; EIF-2 KINASE; ESTRADIOL; HUMANS; IMMUNOPRECIPITATION; MICROSCOPY, ELECTRON, TRANSMISSION; MICROTUBULE-ASSOCIATED PROTEINS; OSTEOSARCOMA; RNA, SMALL INTERFERING; UBIQUITIN-ACTIVATING ENZYMES;

EID: 84875103029     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0059406     Document Type: Article

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