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Volumn 109, Issue 5, 2010, Pages 950-956

2-Methoxyestradiol-mediated anti-tumor effect increases osteoprotegrin expression in osteosarcoma cells

Author keywords

2 Methoxyestradiol; Bone cancer; OPG. OPGL; Osteosarcoma

Indexed keywords

16ALPHA HYDROXYESTRONE; 2 METHOXYESTRADIOL; ANTINEOPLASTIC AGENT; ESTRADIOL; MESSENGER RNA; OSTEOPROTEGERIN;

EID: 77950454179     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.22473     Document Type: Article
Times cited : (13)

References (42)
  • 3
    • 0034319084 scopus 로고    scopus 로고
    • Osteoprotegerin inhibits tumor-induced osteoclastogenesis and bone tumor growth in osteopetrotic mice
    • Clohisy DR, Ramnaraine ML, Scully S, Qi M, Van G, Tan HL, Lacey DL. 2000. Osteoprotegerin inhibits tumor-induced osteoclastogenesis and bone tumor growth in osteopetrotic mice. J Orthop Res 18:967-976.
    • (2000) J Orthop Res , vol.18 , pp. 967-976
    • Clohisy, D.R.1    Ramnaraine, M.L.2    Scully, S.3    Qi, M.4    Van, G.5    Tan, H.L.6    Lacey, D.L.7
  • 5
    • 1942443234 scopus 로고    scopus 로고
    • Serum osteoprotegerin (OPG) levels are associated with disease progression and response to androgen ablation in patients with prostate cancer
    • Eaton CL, Wells JM, Holen I, Croucher PI, Hamdy FC. 2004. Serum osteoprotegerin (OPG) levels are associated with disease progression and response to androgen ablation in patients with prostate cancer. Prostate 59:304-310.
    • (2004) Prostate , vol.59 , pp. 304-310
    • Eaton, C.L.1    Wells, J.M.2    Holen, I.3    Croucher, P.I.4    Hamdy, F.C.5
  • 7
    • 0028220858 scopus 로고
    • The endogenous oestrogen metabolite 2-methoxyoestradiol inhibits angiogenesis and suppresses tumour growth
    • Fotsis T, Zhang Y, Pepper MS, Adlercreutz H, Montesano R, Nawroth PP, Schweigerer L. 1994. The endogenous oestrogen metabolite 2-methoxyoestradiol inhibits angiogenesis and suppresses tumour growth. Nature 368:237-239.
    • (1994) Nature , vol.368 , pp. 237-239
    • Fotsis, T.1    Zhang, Y.2    Pepper, M.S.3    Adlercreutz, H.4    Montesano, R.5    Nawroth, P.P.6    Schweigerer, L.7
  • 8
    • 32944476631 scopus 로고    scopus 로고
    • 2-Methoxyestradiol inhibits prostate tumor development in transgenic adenocarcinoma of mouse prostate: Role of tumor necrosis factor-alpha-stimulated gene 6
    • Garcia GE, Wisniewski HG, Lucia MS, Arevalo N, Slaga TJ, Kraft SL, Strange R, Kumar AP. 2006. 2-Methoxyestradiol inhibits prostate tumor development in transgenic adenocarcinoma of mouse prostate: Role of tumor necrosis factor-alpha-stimulated gene 6. Clin Cancer Res 12:980-988.
    • (2006) Clin Cancer Res , vol.12 , pp. 980-988
    • Garcia, G.E.1    Wisniewski, H.G.2    Lucia, M.S.3    Arevalo, N.4    Slaga, T.J.5    Kraft, S.L.6    Strange, R.7    Kumar, A.P.8
  • 12
    • 4043064387 scopus 로고    scopus 로고
    • Comparison of 10 serum bone turnover markers in prostate carcinoma patients with bone metastatic spread: Diagnostic and prognostic implications
    • Jung K, Lein M, Stephan C, Von Hosslin K, Semjonow A, Sinha P, Loening SA, Schnorr D. 2004. Comparison of 10 serum bone turnover markers in prostate carcinoma patients with bone metastatic spread: Diagnostic and prognostic implications. Int J Cancer 111:783-791.
    • (2004) Int J Cancer , vol.111 , pp. 783-791
    • Jung, K.1    Lein, M.2    Stephan, C.3    Von Hosslin, K.4    Semjonow, A.5    Sinha, P.6    Loening, S.A.7    Schnorr, D.8
  • 14
    • 0035206443 scopus 로고    scopus 로고
    • Minireview: The OPG/RANKL/RANK system
    • Khosla S. 2001. Minireview: The OPG/RANKL/RANK system. Endocrinology 142:5050-5055.
    • (2001) Endocrinology , vol.142 , pp. 5050-5055
    • Khosla, S.1
  • 22
    • 50249178462 scopus 로고    scopus 로고
    • 2-methoxyestradiol-induced cell death in osteosarcoma cells is preceded by cell cycle arrest
    • Maran A, Shogren KL, Benedikt M, Sarkar G, Turner RT, Yaszemski MJ. 2008. 2-methoxyestradiol-induced cell death in osteosarcoma cells is preceded by cell cycle arrest. J Cell Biochem 104:1937-1945.
    • (2008) J Cell Biochem , vol.104 , pp. 1937-1945
    • Maran, A.1    Shogren, K.L.2    Benedikt, M.3    Sarkar, G.4    Turner, R.T.5    Yaszemski, M.J.6
  • 24
    • 0037200838 scopus 로고    scopus 로고
    • Estradiol metabolism and malignant disease
    • Mueck AO, Seeger H, Lippert TH. 2002. Estradiol metabolism and malignant disease. Maturitas 43:1-10.
    • (2002) Maturitas , vol.43 , pp. 1-10
    • Mueck, A.O.1    Seeger, H.2    Lippert, T.H.3
  • 25
    • 0031037067 scopus 로고    scopus 로고
    • Induction of apoptosis in human lung cancer cells after wild-type p53 activation by methoxyestradiol
    • Mukhopadhyay T, Roth JA. 1997. Induction of apoptosis in human lung cancer cells after wild-type p53 activation by methoxyestradiol. Oncogene 14:379-384.
    • (1997) Oncogene , vol.14 , pp. 379-384
    • Mukhopadhyay, T.1    Roth, J.A.2
  • 26
    • 0032537850 scopus 로고    scopus 로고
    • Superinduction of wild-type p53 protein after 2-methoxyestradiol treatment of Ad5p53-transduced cells induces tumor cell apoptosis
    • Mukhopadhyay T, Roth JA. 1998. Superinduction of wild-type p53 protein after 2-methoxyestradiol treatment of Ad5p53-transduced cells induces tumor cell apoptosis. Oncogene 17:241-246.
    • (1998) Oncogene , vol.17 , pp. 241-246
    • Mukhopadhyay, T.1    Roth, J.A.2
  • 31
    • 11144239579 scopus 로고    scopus 로고
    • 2-Methoxyestradiol inhibits hypoxia-inducible factor 1a, tumor growth, and angigenesis and augments paclitaxel efficacy in head and neck squamous cell carcinoma
    • Ricker JL, Chen Z, Yang XP, Pribluda VS, Swartz GM, Waes C. 2004. 2-Methoxyestradiol inhibits hypoxia-inducible factor 1a, tumor growth, and angigenesis and augments paclitaxel efficacy in head and neck squamous cell carcinoma. Clin Cancer Res 10:8665-8673.
    • (2004) Clin Cancer Res , vol.10 , pp. 8665-8673
    • Ricker, J.L.1    Chen, Z.2    Yang, X.P.3    Pribluda, V.S.4    Swartz, G.M.5    Waes, C.6
  • 32
    • 0030924819 scopus 로고    scopus 로고
    • Estrogen regulation of human osteoblastic cell proliferation and differentiation
    • Robinson JA, Harris SA, Riggs BL, Spelsberg TC. 1997. Estrogen regulation of human osteoblastic cell proliferation and differentiation. Endocrinology 138:2919-2927.
    • (1997) Endocrinology , vol.138 , pp. 2919-2927
    • Robinson, J.A.1    Harris, S.A.2    Riggs, B.L.3    Spelsberg, T.C.4
  • 33
    • 0032994838 scopus 로고    scopus 로고
    • Potent antitumor activity of 2-methoxyestradiol in human pancreatic cancer cell lines
    • Schumacher G, Kataoka M, Roth JA, Mukhopadhyay T. 1999. Potent antitumor activity of 2-methoxyestradiol in human pancreatic cancer cell lines. Clin Cancer Res 5:493-499.
    • (1999) Clin Cancer Res , vol.5 , pp. 493-499
    • Schumacher, G.1    Kataoka, M.2    Roth, J.A.3    Mukhopadhyay, T.4
  • 35
    • 33845919594 scopus 로고    scopus 로고
    • Double-stranded RNA-dependent protein kinase is involved in 2-methoxyestradiol-mediated cell death of osteosarcoma cells
    • Shogren KL, Turner RT, Yaszemski MJ, Maran A. 2007. Double-stranded RNA-dependent protein kinase is involved in 2-methoxyestradiol-mediated cell death of osteosarcoma cells. J Bone Miner Res 22:29-36.
    • (2007) J Bone Miner Res , vol.22 , pp. 29-36
    • Shogren, K.L.1    Turner, R.T.2    Yaszemski, M.J.3    Maran, A.4
  • 36
    • 16344381892 scopus 로고    scopus 로고
    • 2-methoxyestradiol is an estrogen receptor agonist that supports tumor growth in murine xenograft models of breast cancer [see comment]
    • Sutherland TE, Schuliga M, Harris T, Eckhardt BL, Anderson RL, Quan L, Stewart AG. 2005. 2-methoxyestradiol is an estrogen receptor agonist that supports tumor growth in murine xenograft models of breast cancer [see comment]. Clin Cancer Res 11:1722-1732.
    • (2005) Clin Cancer Res , vol.11 , pp. 1722-1732
    • Sutherland, T.E.1    Schuliga, M.2    Harris, T.3    Eckhardt, B.L.4    Anderson, R.L.5    Quan, L.6    Stewart, A.G.7
  • 37
    • 0035870297 scopus 로고    scopus 로고
    • The antiangiogenic property of docetaxel is synergistic with a recombinant humanized monoclonal antibody against vascular endothelial growth factor or 2-methoxyestradiol but antagonized by endothelial growth factors
    • Sweeney CJ, Miller KD, Sissons SE, Nozaki S, Heilman DK, Shen J, Sledge GW, Jr. 2001. The antiangiogenic property of docetaxel is synergistic with a recombinant humanized monoclonal antibody against vascular endothelial growth factor or 2-methoxyestradiol but antagonized by endothelial growth factors. Cancer Res 61:3369-3372.
    • (2001) Cancer Res , vol.61 , pp. 3369-3372
    • Sweeney, C.J.1    Miller, K.D.2    Sissons, S.E.3    Nozaki, S.4    Heilman, D.K.5    Shen, J.6    Sledge Jr., G.W.7
  • 38
    • 9244252016 scopus 로고    scopus 로고
    • The molecular triad OPG/RANK/RANKL: Involvement in the orchestration of pathophysiological bone remodeling
    • Theoleyre S, Wittrant Y, Tat SK, Fortun Y, Redini F, Heymann D. 2004. The molecular triad OPG/RANK/RANKL: Involvement in the orchestration of pathophysiological bone remodeling. Cytokine Growth Factor Rev 15:457-475.
    • (2004) Cytokine Growth Factor Rev , vol.15 , pp. 457-475
    • Theoleyre, S.1    Wittrant, Y.2    Tat, S.K.3    Fortun, Y.4    Redini, F.5    Heymann, D.6
  • 39
    • 0034682834 scopus 로고    scopus 로고
    • The osteoblast-specific transcription factor Cbfa1 contributes to the expression of osteoprotegerin, a potent inhibitor of osteoclast differentiation and function
    • Thirunavukkarasu K, Halladay DL, Miles RR, Yang X, Galvin RJ, Chandrasekhar S, Martin TJ, Onyia JE. 2000. The osteoblast-specific transcription factor Cbfa1 contributes to the expression of osteoprotegerin, a potent inhibitor of osteoclast differentiation and function. J Biol Chem 275:25163-25172.
    • (2000) J Biol Chem , vol.275 , pp. 25163-25172
    • Thirunavukkarasu, K.1    Halladay, D.L.2    Miles, R.R.3    Yang, X.4    Galvin, R.J.5    Chandrasekhar, S.6    Martin, T.J.7    Onyia, J.E.8
  • 42
    • 0000317180 scopus 로고    scopus 로고
    • Is 2-methoxyestradiol an endogenous estrogen metabolite that inhibits mammary carcinogenesis?
    • Zhu BT, Conney AH. 1998. Is 2-methoxyestradiol an endogenous estrogen metabolite that inhibits mammary carcinogenesis? Cancer Res 58:2269-2277.
    • (1998) Cancer Res , vol.58 , pp. 2269-2277
    • Zhu, B.T.1    Conney, A.H.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.