-
1
-
-
0037059914
-
A lipophilic thioflavin-T derivative for positron emission tomography (PET) imaging of amyloid in brain
-
Mathis CA, Bacskai BJ, Kajdasz ST, et al. A lipophilic thioflavin-T derivative for positron emission tomography (PET) imaging of amyloid in brain. Bioorg Med Chem Lett. 2002;12:295-298.
-
(2002)
Bioorg Med Chem Lett.
, vol.12
, pp. 295-298
-
-
Mathis, C.A.1
Bacskai, B.J.2
Kajdasz, S.T.3
-
2
-
-
0037444535
-
The binding of 2-(49-methylaminophenyl) benzothiazole to postmortem brain homogenates is dominated by the amyloid component
-
Klunk WE, Wang Y, Huang GF, et al. The binding of 2-(49-methylaminophenyl) benzothiazole to postmortem brain homogenates is dominated by the amyloid component. J Neurosci. 2003;23:2086-2092.
-
(2003)
J Neurosci.
, vol.23
, pp. 2086-2092
-
-
Klunk, W.E.1
Wang, Y.2
Huang, G.F.3
-
3
-
-
10744232413
-
Imaging brain amyloid in Alzheimer's disease with Pittsburgh compound-B
-
Klunk WE, Engler H, Nordberg A, et al. Imaging brain amyloid in Alzheimer's disease with Pittsburgh compound-B. Ann Neurol. 2004;55:306-319.
-
(2004)
Ann Neurol.
, vol.55
, pp. 306-319
-
-
Klunk, W.E.1
Engler, H.2
Nordberg, A.3
-
6
-
-
78751546481
-
Use of florbetapir-PET for imaging beta-amyloid pathology
-
Clark CM, Schneider JA, Bedell BJ, et al. Use of florbetapir-PET for imaging beta-amyloid pathology. JAMA. 2011;305:275-283.
-
(2011)
JAMA.
, vol.305
, pp. 275-283
-
-
Clark, C.M.1
Schneider, J.A.2
Bedell, B.J.3
-
7
-
-
77956384880
-
18F-flutemetamol amyloid imaging in Alzheimer disease and mild cognitive impairment: a phase 2 trial
-
18F-flutemetamol amyloid imaging in Alzheimer disease and mild cognitive impairment: a phase 2 trial. Ann Neurol. 2010;68:319-329.
-
(2010)
Ann Neurol.
, vol.68
, pp. 319-329
-
-
Vandenberghe, R.1
Van Laere, K.2
Ivanoiu, A.3
-
8
-
-
79954748692
-
18F) in patients with Alzheimer's disease and healthy controls: a multicentre phase 2 diagnostic study
-
18F) in patients with Alzheimer's disease and healthy controls: a multicentre phase 2 diagnostic study. Lancet Neurol. 2011;10:424-435.
-
(2011)
Lancet Neurol.
, vol.10
, pp. 424-435
-
-
Barthel, H.1
Gertz, H.J.2
Dresel, S.3
-
10
-
-
33646437238
-
Neuropathologic outcome of mild cognitive impairment following progression to clinical dementia
-
Jicha GA, Parisi JE, Dickson DW, et al. Neuropathologic outcome of mild cognitive impairment following progression to clinical dementia. Arch Neurol. 2006;63:674-681.
-
(2006)
Arch Neurol.
, vol.63
, pp. 674-681
-
-
Jicha, G.A.1
Parisi, J.E.2
Dickson, D.W.3
-
11
-
-
0033859794
-
The epidemic of Alzheimer's disease: how can we manage the costs?
-
Johnson N, Davis T, Bosanquet N. The epidemic of Alzheimer's disease: how can we manage the costs? Pharmacoeconomics. 2000;18:215-223.
-
(2000)
Pharmacoeconomics
, vol.18
, pp. 215-223
-
-
Johnson, N.1
Davis, T.2
Bosanquet, N.3
-
12
-
-
77949300796
-
11C-PiB PET assessment of change in fibrillar amyloid-beta load in patients with Alzheimer's disease treated with bapineuzumab: a phase 2, double-blind, placebo-controlled, ascending-dose study
-
11C-PiB PET assessment of change in fibrillar amyloid-beta load in patients with Alzheimer's disease treated with bapineuzumab: a phase 2, double-blind, placebo-controlled, ascending-dose study. Lancet Neurol. 2010;9:363-372.
-
(2010)
Lancet Neurol.
, vol.9
, pp. 363-372
-
-
Rinne, J.O.1
Brooks, D.J.2
Rossor, M.N.3
-
13
-
-
0031593592
-
Neuropathology of Alzheimer's disease: a critical update
-
Jellinger KA, Bancher C. Neuropathology of Alzheimer's disease: a critical update. J Neural Transm Suppl. 1998;54:77-95.
-
(1998)
J Neural Transm Suppl.
, vol.54
, pp. 77-95
-
-
Jellinger, K.A.1
Bancher, C.2
-
14
-
-
33750904708
-
Neuropathology of Alzheimer's disease
-
Burns A, O'Brien J, Ames D, eds. 3rd ed. London, U.K.: Hodder Arnold
-
Masters CL. Neuropathology of Alzheimer's disease. In: Burns A, O'Brien J, Ames D, eds. Dementia. 3rd ed. London, U.K.: Hodder Arnold; 2005:393-407.
-
(2005)
Dementia
, pp. 393-407
-
-
Masters, C.L.1
-
15
-
-
0031302684
-
Staging of Alzheimer-related cortical destruction
-
Braak H, Braak E. Staging of Alzheimer-related cortical destruction. Int Psychogeriatr. 1997;9(suppl 1):257-261.
-
(1997)
Int Psychogeriatr.
, vol.9
, Issue.SUPPL. 1
, pp. 257-261
-
-
Braak, H.1
Braak, E.2
-
16
-
-
0030805991
-
Frequency of stages of Alzheimer-related lesions in different age categories
-
Braak H, Braak E. Frequency of stages of Alzheimer-related lesions in different age categories. Neurobiol Aging. 1997;18:351-357.
-
(1997)
Neurobiol Aging.
, vol.18
, pp. 351-357
-
-
Braak, H.1
Braak, E.2
-
17
-
-
0026740795
-
Neurofibrillary tangles but not senile plaques parallel duration and severity of Alzheimer's disease
-
Arriagada PV, Growdon JH, Hedley-Whyte ET, Hyman BT. Neurofibrillary tangles but not senile plaques parallel duration and severity of Alzheimer's disease. Neurology. 1992;42:631-639.
-
(1992)
Neurology.
, vol.42
, pp. 631-639
-
-
Arriagada, P.V.1
Growdon, J.H.2
Hedley-Whyte, E.T.3
Hyman, B.T.4
-
18
-
-
0038117796
-
Correlation between elevated levels of amyloid beta-peptide in the brain and cognitive decline
-
Näslund J, Haroutunian V, Mohs R, et al. Correlation between elevated levels of amyloid beta-peptide in the brain and cognitive decline. JAMA. 2000;283: 1571-1577.
-
(2000)
JAMA.
, vol.283
, pp. 1571-1577
-
-
Näslund, J.1
Haroutunian, V.2
Mohs, R.3
-
19
-
-
0032590054
-
Soluble pool of Ab amyloid as a determinant of severity of neurodegeneration in Alzheimer's disease
-
McLean CA, Cherny RA, Fraser FW, et al. Soluble pool of Ab amyloid as a determinant of severity of neurodegeneration in Alzheimer's disease. Ann Neurol. 1999;46:860-866.
-
(1999)
Ann Neurol.
, vol.46
, pp. 860-866
-
-
McLean, C.A.1
Cherny, R.A.2
Fraser, F.W.3
-
20
-
-
33745027879
-
Molecular mechanisms for Alzheimer's disease: implications for neuroimaging and therapeutics
-
Masters CL, Cappai R, Barnham KJ, Villemagne VL. Molecular mechanisms for Alzheimer's disease: implications for neuroimaging and therapeutics. J Neurochem. 2006;97:1700-1725.
-
(2006)
J Neurochem.
, vol.97
, pp. 1700-1725
-
-
Masters, C.L.1
Cappai, R.2
Barnham, K.J.3
Villemagne, V.L.4
-
21
-
-
0026597063
-
Alzheimer's disease: the amyloid cascade hypothesis
-
Hardy JA, Higgins GA. Alzheimer's disease: the amyloid cascade hypothesis. Science. 1992;256:184-185.
-
(1992)
Science.
, vol.256
, pp. 184-185
-
-
Hardy, J.A.1
Higgins, G.A.2
-
22
-
-
0031052381
-
Amyloid, the presenilins and Alzheimer's disease
-
Hardy J. Amyloid, the presenilins and Alzheimer's disease. Trends Neurosci. 1997;20:154-159.
-
(1997)
Trends Neurosci.
, vol.20
, pp. 154-159
-
-
Hardy, J.1
-
23
-
-
0035950188
-
New frontiers in Alzheimer's disease genetics
-
Tanzi RE, Bertram L. New frontiers in Alzheimer's disease genetics. Neuron. 2001;32:181-184.
-
(2001)
Neuron.
, vol.32
, pp. 181-184
-
-
Tanzi, R.E.1
Bertram, L.2
-
24
-
-
0021271971
-
Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease
-
McKhann G, Drachman D, Folstein M, Katzman R, Price D, Stadlan EM. Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology. 1984;34:939-944.
-
(1984)
Neurology.
, vol.34
, pp. 939-944
-
-
McKhann, G.1
Drachman, D.2
Folstein, M.3
Katzman, R.4
Price, D.5
Stadlan, E.M.6
-
25
-
-
0035826782
-
Practice parameter: diagnosis of dementia (an evidence based review)-report of the Quality Standards Subcommittee of the American Academy of Neurology
-
Knopman DS, DeKosky ST, Cummings JL, et al. Practice parameter: diagnosis of dementia (an evidence based review)-report of the Quality Standards Subcommittee of the American Academy of Neurology. Neurology. 2001;56:1143-1153.
-
(2001)
Neurology.
, vol.56
, pp. 1143-1153
-
-
Knopman, D.S.1
DeKosky, S.T.2
Cummings, J.L.3
-
26
-
-
79956142378
-
The diagnosis of dementia due to Alzheimer's disease: recommendations from the National Institute on Aging- Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease
-
McKhann GM, Knopman DS, Chertkow H, et al. The diagnosis of dementia due to Alzheimer's disease: recommendations from the National Institute on Aging- Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease. Alzheimers Dement. 2011;7:263-269.
-
(2011)
Alzheimers Dement.
, vol.7
, pp. 263-269
-
-
McKhann, G.M.1
Knopman, D.S.2
Chertkow, H.3
-
27
-
-
37349048311
-
Biomarkers for early detection of Alzheimer pathology
-
Clark CM, Davatzikos C, Borthakur A, et al. Biomarkers for early detection of Alzheimer pathology. Neurosignals. 2008;16:11-18.
-
(2008)
Neurosignals.
, vol.16
, pp. 11-18
-
-
Clark, C.M.1
Davatzikos, C.2
Borthakur, A.3
-
28
-
-
33644832047
-
Inverse relation between in vivo amyloid imaging load and cerebrospinal fluid Abeta(42) in humans
-
Fagan AM, Mintun MA, Mach RH, et al. Inverse relation between in vivo amyloid imaging load and cerebrospinal fluid Abeta(42) in humans. Ann Neurol. 2006;59:512-519.
-
(2006)
Ann Neurol.
, vol.59
, pp. 512-519
-
-
Fagan, A.M.1
Mintun, M.A.2
Mach, R.H.3
-
29
-
-
72049130805
-
Hypothetical model of dynamic biomarkers of the Alzheimer's pathological cascade
-
Jack CR Jr, Knopman DS, Jagust WJ, et al. Hypothetical model of dynamic biomarkers of the Alzheimer's pathological cascade. Lancet Neurol. 2010;9:119-128.
-
(2010)
Lancet Neurol.
, vol.9
, pp. 119-128
-
-
Jack Jr., C.R.1
Knopman, D.S.2
Jagust, W.J.3
-
30
-
-
33947729229
-
Biomarkers of neurodegeneration for diagnosis and monitoring therapeutics
-
Shaw LM, Korecka M, Clark CM, Lee VM, Trojanowski JQ. Biomarkers of neurodegeneration for diagnosis and monitoring therapeutics. Nat Rev Drug Discov. 2007;6:295-303.
-
(2007)
Nat Rev Drug Discov.
, vol.6
, pp. 295-303
-
-
Shaw, L.M.1
Korecka, M.2
Clark, C.M.3
Lee, V.M.4
Trojanowski, J.Q.5
-
31
-
-
10044248896
-
Contribution of structural neuroimaging to the early diagnosis of Alzheimer's disease
-
de Leon MJ, Convit A, DeSanti S, et al. Contribution of structural neuroimaging to the early diagnosis of Alzheimer's disease. Int Psychogeriatr. 1997;9:183-190.
-
(1997)
Int Psychogeriatr.
, vol.9
, pp. 183-190
-
-
de Leon, M.J.1
Convit, A.2
DeSanti, S.3
-
32
-
-
0034127931
-
Use of structural magnetic resonance imaging to predict who will get Alzheimer's disease
-
Killiany RJ, Gomez-Isla T, Moss M, et al. Use of structural magnetic resonance imaging to predict who will get Alzheimer's disease. Ann Neurol. 2000; 47:430-439.
-
(2000)
Ann Neurol.
, vol.47
, pp. 430-439
-
-
Killiany, R.J.1
Gomez-Isla, T.2
Moss, M.3
-
33
-
-
0034624914
-
Usefulness of MRI measures of entorhinal cortex versus hippocampus in AD
-
Xu Y, Jack CR Jr, O'Brien PC, et al. Usefulness of MRI measures of entorhinal cortex versus hippocampus in AD. Neurology. 2000;54:1760-1767.
-
(2000)
Neurology.
, vol.54
, pp. 1760-1767
-
-
Xu, Y.1
Jack Jr., C.R.2
O'Brien, P.C.3
-
34
-
-
0035824167
-
Positron emission tomography in evaluation of dementia: regional brain metabolism and long-term outcome
-
Silverman DH, Small GW, Chang CY, et al. Positron emission tomography in evaluation of dementia: regional brain metabolism and long-term outcome. JAMA. 2001;286:2120-2127.
-
(2001)
JAMA.
, vol.286
, pp. 2120-2127
-
-
Silverman, D.H.1
Small, G.W.2
Chang, C.Y.3
-
36
-
-
34248579291
-
Imaging beta-amyloid burden in aging and dementia
-
Rowe CC, Ng S, Ackermann U, et al. Imaging beta-amyloid burden in aging and dementia. Neurology. 2007;68:1718-1725.
-
(2007)
Neurology.
, vol.68
, pp. 1718-1725
-
-
Rowe, C.C.1
Ng, S.2
Ackermann, U.3
-
37
-
-
0032988610
-
Mild cognitive impairment: clinical characterization and outcome
-
Petersen RC, Smith GE, Waring SC, Ivnik RJ, Tangalos EG, Kokmen E. Mild cognitive impairment: clinical characterization and outcome. Arch Neurol. 1999; 56:303-308.
-
(1999)
Arch Neurol.
, vol.56
, pp. 303-308
-
-
Petersen, R.C.1
Smith, G.E.2
Waring, S.C.3
Ivnik, R.J.4
Tangalos, E.G.5
Kokmen, E.6
-
38
-
-
0034087231
-
Mild cognitive impairment: transition between aging and Alzheimer's disease
-
Petersen RC. Mild cognitive impairment: transition between aging and Alzheimer's disease. Neurologia. 2000;15:93-101.
-
(2000)
Neurologia.
, vol.15
, pp. 93-101
-
-
Petersen, R.C.1
-
39
-
-
77957951112
-
Revising the definition of Alzheimer's disease: a new lexicon
-
Dubois B, Feldman HH, Jacova C, et al. Revising the definition of Alzheimer's disease: a new lexicon. Lancet Neurol. 2010;9:1118-1127.
-
(2010)
Lancet Neurol.
, vol.9
, pp. 1118-1127
-
-
Dubois, B.1
Feldman, H.H.2
Jacova, C.3
-
40
-
-
79956084514
-
The diagnosis of mild cognitive impairment due to Alzheimer's disease: Recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease
-
Albert MS, Dekosky ST, Dickson D, et al. The diagnosis of mild cognitive impairment due to Alzheimer's disease: Recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease. Alzheimers Dement. 2011;7:270-279.
-
(2011)
Alzheimers Dement.
, vol.7
, pp. 270-279
-
-
Albert, M.S.1
Dekosky, S.T.2
Dickson, D.3
-
41
-
-
0035826925
-
Practice parameter: early detection of dementia: mild cognitive impairment (an evidence-based review). Report of the Quality Standards Subcommittee of the American Academy of Neurology
-
Petersen RC, Stevens JC, Ganguli M, Tangalos EG, Cummings JL, DeKosky ST. Practice parameter: early detection of dementia: mild cognitive impairment (an evidence-based review). Report of the Quality Standards Subcommittee of the American Academy of Neurology. Neurology. 2001;56:1133-1142.
-
(2001)
Neurology.
, vol.56
, pp. 1133-1142
-
-
Petersen, R.C.1
Stevens, J.C.2
Ganguli, M.3
Tangalos, E.G.4
Cummings, J.L.5
DeKosky, S.T.6
-
42
-
-
33846906502
-
Mild cognitive impairment: current research and clinical implications
-
Petersen RC. Mild cognitive impairment: current research and clinical implications. Semin Neurol. 2007;27:22-31.
-
(2007)
Semin Neurol.
, vol.27
, pp. 22-31
-
-
Petersen, R.C.1
-
43
-
-
0032989712
-
Tangles and plaques in nondemented aging and "preclinical" Alzheimer's disease
-
Price JL, Morris JC. Tangles and plaques in nondemented aging and "preclinical" Alzheimer's disease. Ann Neurol. 1999;45:358-368.
-
(1999)
Ann Neurol.
, vol.45
, pp. 358-368
-
-
Price, J.L.1
Morris, J.C.2
-
44
-
-
33745876233
-
Neuropathology of older persons without cognitive impairment from two community-based studies
-
Bennett DA, Schneider JA, Arvanitakis Z, et al. Neuropathology of older persons without cognitive impairment from two community-based studies. Neurology. 2006;66:1837-1844.
-
(2006)
Neurology.
, vol.66
, pp. 1837-1844
-
-
Bennett, D.A.1
Schneider, J.A.2
Arvanitakis, Z.3
-
45
-
-
77954033257
-
Amyloid imaging results from the Australian Imaging, Biomarkers and Lifestyle (AIBL) study of aging
-
Rowe CC, Ellis KA, Rimajova M, et al. Amyloid imaging results from the Australian Imaging, Biomarkers and Lifestyle (AIBL) study of aging. Neurobiol Aging. 2010;31:1275-1283.
-
(2010)
Neurobiol Aging.
, vol.31
, pp. 1275-1283
-
-
Rowe, C.C.1
Ellis, K.A.2
Rimajova, M.3
-
46
-
-
79551495391
-
Longitudinal assessment of Abeta and cognition in aging and Alzheimer disease
-
Villemagne VL, Pike KE, Chetelat G, et al. Longitudinal assessment of Abeta and cognition in aging and Alzheimer disease. Ann Neurol. 2011;69:181-192.
-
(2011)
Ann Neurol.
, vol.69
, pp. 181-192
-
-
Villemagne, V.L.1
Pike, K.E.2
Chetelat, G.3
-
47
-
-
79956098248
-
Toward defining the preclinical stages of Alzheimer's disease: recommendations from the National Institute on Aging- Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease
-
Sperling RA, Aisen PS, Beckett LA, et al. Toward defining the preclinical stages of Alzheimer's disease: recommendations from the National Institute on Aging- Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease. Alzheimers Dement. 2011;7:280-292.
-
(2011)
Alzheimers Dement.
, vol.7
, pp. 280-292
-
-
Sperling, R.A.1
Aisen, P.S.2
Beckett, L.A.3
-
48
-
-
33750603844
-
Alzheimer's centennial legacy: prospects for rational therapeutic intervention targeting the Abeta amyloid pathway
-
Masters CL, Beyreuther K. Alzheimer's centennial legacy: prospects for rational therapeutic intervention targeting the Abeta amyloid pathway. Brain. 2006; 129:2823-2839.
-
(2006)
Brain.
, vol.129
, pp. 2823-2839
-
-
Masters, C.L.1
Beyreuther, K.2
-
49
-
-
14844303913
-
Evidence for the presence of three distinct binding sites for the thioflavin T class of Alzheimer's disease PET imaging agents on beta-amyloid peptide fibrils
-
Lockhart A, Ye L, Judd DB, et al. Evidence for the presence of three distinct binding sites for the thioflavin T class of Alzheimer's disease PET imaging agents on beta-amyloid peptide fibrils. J Biol Chem. 2005;280:7677-7684.
-
(2005)
J Biol Chem.
, vol.280
, pp. 7677-7684
-
-
Lockhart, A.1
Ye, L.2
Judd, D.B.3
-
50
-
-
21244492425
-
Delineation of positron emission tomography imaging agent binding sites on beta-amyloid peptide fibrils
-
Ye L, Morgenstern JL, Gee AD, Hong G, Brown J, Lockhart A. Delineation of positron emission tomography imaging agent binding sites on beta-amyloid peptide fibrils. J Biol Chem. 2005;280:23599-23604.
-
(2005)
J Biol Chem.
, vol.280
, pp. 23599-23604
-
-
Ye, L.1
Morgenstern, J.L.2
Gee, A.D.3
Hong, G.4
Brown, J.5
Lockhart, A.6
-
51
-
-
34447326955
-
Amyloid imaging in Alzheimer's disease
-
Nordberg A. Amyloid imaging in Alzheimer's disease. Curr Opin Neurol. 2007; 20:398-402.
-
(2007)
Curr Opin Neurol.
, vol.20
, pp. 398-402
-
-
Nordberg, A.1
-
52
-
-
33947223454
-
Cerebrospinal fluid tau/beta-amyloid(42) ratio as a prediction of cognitive decline in nondemented older adults
-
Fagan AM, Roe CM, Xiong C, Mintun MA, Morris JC, Holtzman DM. Cerebrospinal fluid tau/beta-amyloid(42) ratio as a prediction of cognitive decline in nondemented older adults. Arch Neurol. 2007;64:343-349.
-
(2007)
Arch Neurol.
, vol.64
, pp. 343-349
-
-
Fagan, A.M.1
Roe, C.M.2
Xiong, C.3
Mintun, M.A.4
Morris, J.C.5
Holtzman, D.M.6
-
53
-
-
35648932901
-
Beta-amyloid imaging and memory in non-demented individuals: evidence for preclinical Alzheimer's disease
-
Pike KE, Savage G, Villemagne VL, et al. Beta-amyloid imaging and memory in non-demented individuals: evidence for preclinical Alzheimer's disease. Brain. 2007;130:2837-2844.
-
(2007)
Brain.
, vol.130
, pp. 2837-2844
-
-
Pike, K.E.1
Savage, G.2
Villemagne, V.L.3
-
54
-
-
43849084404
-
Abeta deposits in older non-demented individuals with cognitive decline are indicative of preclinical Alzheimer's disease
-
Villemagne VL, Pike KE, Darby D, et al. Abeta deposits in older non-demented individuals with cognitive decline are indicative of preclinical Alzheimer's disease. Neuropsychologia. 2008;46:1688-1697.
-
(2008)
Neuropsychologia.
, vol.46
, pp. 1688-1697
-
-
Villemagne, V.L.1
Pike, K.E.2
Darby, D.3
-
55
-
-
33947198109
-
Molecular imaging with Pittsburgh compound B confirmed at autopsy: a case report
-
Bacskai BJ, Frosch MP, Freeman SH, et al. Molecular imaging with Pittsburgh compound B confirmed at autopsy: a case report. Arch Neurol. 2007;64:431-434.
-
(2007)
Arch Neurol.
, vol.64
, pp. 431-434
-
-
Bacskai, B.J.1
Frosch, M.P.2
Freeman, S.H.3
-
56
-
-
43849083580
-
Post-mortem correlates of in vivo PiB-PET amyloid imaging in a typical case of Alzheimer's disease
-
Ikonomovic MD, Klunk WE, Abrahamson EE, et al. Post-mortem correlates of in vivo PiB-PET amyloid imaging in a typical case of Alzheimer's disease. Brain. 2008;131:1630-1645.
-
(2008)
Brain.
, vol.131
, pp. 1630-1645
-
-
Ikonomovic, M.D.1
Klunk, W.E.2
Abrahamson, E.E.3
-
57
-
-
54049120245
-
Assessment of beta-amyloid in a frontal cortical brain biopsy specimen and by positron emission tomography with carbon 11-labeled Pittsburgh compound B
-
Leinonen V, Alafuzoff I, Aalto S, et al. Assessment of beta-amyloid in a frontal cortical brain biopsy specimen and by positron emission tomography with carbon 11-labeled Pittsburgh compound B. Arch Neurol. 2008;65:1304-1309.
-
(2008)
Arch Neurol.
, vol.65
, pp. 1304-1309
-
-
Leinonen, V.1
Alafuzoff, I.2
Aalto, S.3
-
58
-
-
33747048954
-
11C]PIB in a nondemented population: potential antecedent marker of Alzheimer disease
-
11C]PIB in a nondemented population: potential antecedent marker of Alzheimer disease. Neurology. 2006;67:446-452.
-
(2006)
Neurology.
, vol.67
, pp. 446-452
-
-
Mintun, M.A.1
Larossa, G.N.2
Sheline, Y.I.3
-
59
-
-
55949117032
-
Frequent amyloid deposition without significant cognitive impairment among the elderly
-
Aizenstein HJ, Nebes RD, Saxton JA, et al. Frequent amyloid deposition without significant cognitive impairment among the elderly. Arch Neurol. 2008;65:1509-1517.
-
(2008)
Arch Neurol.
, vol.65
, pp. 1509-1517
-
-
Aizenstein, H.J.1
Nebes, R.D.2
Saxton, J.A.3
-
60
-
-
0027407565
-
Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease
-
Strittmatter WJ, Saunders AM, Schmechel D, et al. Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease. Proc Natl Acad Sci USA. 1993;90:1977-1981.
-
(1993)
Proc Natl Acad Sci USA.
, vol.90
, pp. 1977-1981
-
-
Strittmatter, W.J.1
Saunders, A.M.2
Schmechel, D.3
-
61
-
-
66149084048
-
Fibrillar amyloid-beta burden in cognitively normal people at 3 levels of genetic risk for Alzheimer's disease
-
Reiman EM, Chen K, Liu X, et al. Fibrillar amyloid-beta burden in cognitively normal people at 3 levels of genetic risk for Alzheimer's disease. Proc Natl Acad Sci USA. 2009;106:6820-6825.
-
(2009)
Proc Natl Acad Sci USA.
, vol.106
, pp. 6820-6825
-
-
Reiman, E.M.1
Chen, K.2
Liu, X.3
-
63
-
-
27544513056
-
Kinetic modeling of amyloid binding in humans using PET imaging and Pittsburgh compound-B
-
Price JC, Klunk WE, Lopresti BJ, et al. Kinetic modeling of amyloid binding in humans using PET imaging and Pittsburgh compound-B. J Cereb Blood Flow Metab. 2005;25:1528-1547.
-
(2005)
J Cereb Blood Flow Metab.
, vol.25
, pp. 1528-1547
-
-
Price, J.C.1
Klunk, W.E.2
Lopresti, B.J.3
-
64
-
-
49349092320
-
PET imaging of amyloid deposition in patients with mild cognitive impairment
-
Forsberg A, Engler H, Almkvist O, et al. PET imaging of amyloid deposition in patients with mild cognitive impairment. Neurobiol Aging. 2008;29:1456-1465.
-
(2008)
Neurobiol Aging.
, vol.29
, pp. 1456-1465
-
-
Forsberg, A.1
Engler, H.2
Almkvist, O.3
-
66
-
-
34948819200
-
Imaging of amyloid burden and distribution in cerebral amyloid angiopathy
-
Johnson KA, Gregas M, Becker JA, et al. Imaging of amyloid burden and distribution in cerebral amyloid angiopathy. Ann Neurol. 2007;62:229-234.
-
(2007)
Ann Neurol.
, vol.62
, pp. 229-234
-
-
Johnson, K.A.1
Gregas, M.2
Becker, J.A.3
-
67
-
-
76649142080
-
11C-PIB binding is increased in patients with cerebral amyloid angiopathy-related hemorrhage
-
11C-PIB binding is increased in patients with cerebral amyloid angiopathy-related hemorrhage. Neurology. 2010; 74:487-493.
-
(2010)
Neurology.
, vol.74
, pp. 487-493
-
-
Ly, J.V.1
Donnan, G.A.2
Villemagne, V.L.3
-
68
-
-
34249984684
-
Amyloid deposition begins in the striatum of presenilin-1 mutation carriers from two unrelated pedigrees
-
Klunk WE, Price JC, Mathis CA, et al. Amyloid deposition begins in the striatum of presenilin-1 mutation carriers from two unrelated pedigrees. J Neurosci. 2007;27:6174-6184.
-
(2007)
J Neurosci.
, vol.27
, pp. 6174-6184
-
-
Klunk, W.E.1
Price, J.C.2
Mathis, C.A.3
-
69
-
-
46849093845
-
11C]PIB uptake shows predominantly striatal increase in variant Alzheimer's disease
-
11C]PIB uptake shows predominantly striatal increase in variant Alzheimer's disease. Brain. 2008;131:1845-1853.
-
(2008)
Brain.
, vol.131
, pp. 1845-1853
-
-
Koivunen, J.1
Verkkoniemi, A.2
Aalto, S.3
-
70
-
-
73549108133
-
High striatal amyloid beta-peptide deposition across different autosomal Alzheimer disease mutation types
-
Villemagne VL, Ataka S, Mizuno T, et al. High striatal amyloid beta-peptide deposition across different autosomal Alzheimer disease mutation types. Arch Neurol. 2009;66:1537-1544.
-
(2009)
Arch Neurol.
, vol.66
, pp. 1537-1544
-
-
Villemagne, V.L.1
Ataka, S.2
Mizuno, T.3
-
71
-
-
84875025763
-
-
FDA Advisory Committee Briefing Document: NDA #202-008-Florbetapir F18 Injection. U.S. Food and Drug Administration Web site
-
FDA Advisory Committee Briefing Document: NDA #202-008-Florbetapir F18 Injection. U.S. Food and Drug Administration Web site. http://www.fda.gov/downloads/AdvisoryCommittees/CommitteesMeetingMateria ls/Drugs/PeripheralandCentralNervousSystemDrugsAdvisoryCommittee/UCM2402 66.pdf.
-
-
-
-
72
-
-
73549123897
-
Absence of Pittsburgh compound B detection of cerebral amyloid beta in a patient with clinical, cognitive, and cerebrospinal fluid markers of Alzheimer disease: a case report
-
Cairns NJ, Ikonomovic MD, Benzinger T, et al. Absence of Pittsburgh compound B detection of cerebral amyloid beta in a patient with clinical, cognitive, and cerebrospinal fluid markers of Alzheimer disease: a case report. Arch Neurol. 2009;66:1557-1562.
-
(2009)
Arch Neurol.
, vol.66
, pp. 1557-1562
-
-
Cairns, N.J.1
Ikonomovic, M.D.2
Benzinger, T.3
-
73
-
-
36149001032
-
Imaging of amyloid plaques and cerebral glucose metabolism in semantic dementia and Alzheimer's disease
-
Drzezga A, Grimmer T, Henriksen G, et al. Imaging of amyloid plaques and cerebral glucose metabolism in semantic dementia and Alzheimer's disease. Neuroimage. 2008;39:619-633.
-
(2008)
Neuroimage.
, vol.39
, pp. 619-633
-
-
Drzezga, A.1
Grimmer, T.2
Henriksen, G.3
-
75
-
-
34247196532
-
11C-PIB PET imaging in Alzheimer disease and frontotemporal lobar degeneration
-
11C-PIB PET imaging in Alzheimer disease and frontotemporal lobar degeneration. Neurology. 2007;68:1205-1212.
-
(2007)
Neurology
, vol.68
, pp. 1205-1212
-
-
Rabinovici, G.D.1
Furst, A.J.2
O'Neil, J.P.3
|